scholarly journals Design of Three-Dimensional Scaffolds with Tunable Matrix Stiffness for Directing Stem Cell Lineage Specification: An In Silico Study

2017 ◽  
Vol 4 (4) ◽  
pp. 66 ◽  
Author(s):  
Sanjairaj Vijayavenkataraman ◽  
Zhang Shuo ◽  
Jerry Fuh ◽  
Wen Lu
Keyword(s):  
Stem Cell ◽  
In Silico ◽  
Three Dimensional ◽  
Cell Lineage ◽  
Matrix Stiffness ◽  
Lineage Specification ◽  
Stem Cell Lineage ◽  
In Silico Study

Hematopoietic stem cell lineage specification

2016 ◽  
Vol 23 (4) ◽  
pp. 311-317 ◽  
Author(s):  
Marie Pouzolles ◽  
Leal Oburoglu ◽  
Naomi Taylor ◽  
Valérie S. Zimmermann
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell ◽  
Cell Lineage ◽  
Lineage Specification ◽  
Hematopoietic Stem ◽  
Stem Cell Lineage

scholarly journals Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis

2017 ◽  
Vol 1860 (4) ◽  
pp. 438-449 ◽  
Author(s):  
Hai Wu ◽  
Jonathan A.R. Gordon ◽  
Troy W. Whitfield ◽  
Phillip W.L. Tai ◽  
Andre J. van Wijnen ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Lineage ◽  
Lineage Specification ◽  
Chromatin Dynamics ◽  
Stem Cell Lineage

scholarly journals Stem Cell Lineage Specification: You Become What You Eat

2014 ◽  
Vol 20 (3) ◽  
pp. 389-391 ◽  
Author(s):  
Clifford D.L. Folmes ◽  
Andre Terzic
Keyword(s):  
Stem Cell ◽  
Cell Lineage ◽  
Lineage Specification ◽  
Stem Cell Lineage

scholarly journals Biomimetic three-dimensional microenvironment for controlling stem cell fate

2011 ◽  
Vol 1 (5) ◽  
pp. 792-803 ◽  
Author(s):  
Hu Zhang ◽  
Sheng Dai ◽  
Jingxiu Bi ◽  
Kuo-Kang Liu
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Three Dimensional ◽  
Cell Lineage ◽  
Cell Interaction ◽  
Stem Cell Fate ◽  
Cell Microenvironment ◽  
Stem Cell Lineage ◽  
Matrix Cell ◽  
The Individual

Stem cell therapy is an emerging technique which is being translated into treatment of degenerated tissues. However, the success of translation relies on the stem cell lineage commitment in the degenerated regions of interest. This commitment is precisely controlled by the stem cell microenvironment. Engineering a biomimetic three-dimensional microenvironment enables a thorough understanding of the mechanisms of governing stem cell fate. We review the individual microenvironment components, including soluble factors, extracellular matrix, cell–cell interaction and mechanical stimulation. The perspectives in creating the biomimetic microenvironments are discussed with emerging techniques.

Sign in / Sign up

Export Citation Format

Share Document