scholarly journals Explainable COVID-19 Detection on Chest X-rays Using an End-to-End Deep Convolutional Neural Network Architecture

2021 ◽  
Vol 5 (4) ◽  
pp. 73
Author(s):  
Mohamed Chetoui ◽  
Moulay A. Akhloufi ◽  
Bardia Yousefi ◽  
El Mostafa Bouattane
Keyword(s):  
Deep Learning ◽  
Medical Imaging ◽  
Network Architecture ◽  
Learning Algorithm ◽  
Binary Classification ◽  
X Rays ◽  
Deep Learning Algorithm ◽  
Binary Model ◽  
Chest X Ray ◽  
Multi Class Classification

The coronavirus pandemic is spreading around the world. Medical imaging modalities such as radiography play an important role in the fight against COVID-19. Deep learning (DL) techniques have been able to improve medical imaging tools and help radiologists to make clinical decisions for the diagnosis, monitoring and prognosis of different diseases. Computer-Aided Diagnostic (CAD) systems can improve work efficiency by precisely delineating infections in chest X-ray (CXR) images, thus facilitating subsequent quantification. CAD can also help automate the scanning process and reshape the workflow with minimal patient contact, providing the best protection for imaging technicians. The objective of this study is to develop a deep learning algorithm to detect COVID-19, pneumonia and normal cases on CXR images. We propose two classifications problems, (i) a binary classification to classify COVID-19 and normal cases and (ii) a multiclass classification for COVID-19, pneumonia and normal. Nine datasets and more than 3200 COVID-19 CXR images are used to assess the efficiency of the proposed technique. The model is trained on a subset of the National Institute of Health (NIH) dataset using swish activation, thus improving the training accuracy to detect COVID-19 and other pneumonia. The models are tested on eight merged datasets and on individual test sets in order to confirm the degree of generalization of the proposed algorithms. An explainability algorithm is also developed to visually show the location of the lung-infected areas detected by the model. Moreover, we provide a detailed analysis of the misclassified images. The obtained results achieve high performances with an Area Under Curve (AUC) of 0.97 for multi-class classification (COVID-19 vs. other pneumonia vs. normal) and 0.98 for the binary model (COVID-19 vs. normal). The average sensitivity and specificity are 0.97 and 0.98, respectively. The sensitivity of the COVID-19 class achieves 0.99. The results outperformed the comparable state-of-the-art models for the detection of COVID-19 on CXR images. The explainability model shows that our model is able to efficiently identify the signs of COVID-19.

scholarly journals Detecting Coronavirus from Chest X-rays Using Transfer Learning

COVID ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 403-415
Author(s):  
Abeer Badawi ◽  
Khalid Elgazzar
Keyword(s):  
Deep Learning ◽  
Binary Classification ◽  
Healthcare Providers ◽  
Large Set ◽  
X Rays ◽  
Learning Models ◽  
X Ray ◽  
Chest X Ray ◽  
Multi Class Classification ◽  
Novel Coronavirus

Coronavirus disease (COVID-19) is an illness caused by a novel coronavirus family. One of the practical examinations for COVID-19 is chest radiography. COVID-19 infected patients show abnormalities in chest X-ray images. However, examining the chest X-rays requires a specialist with high experience. Hence, using deep learning techniques in detecting abnormalities in the X-ray images is presented commonly as a potential solution to help diagnose the disease. Numerous research has been reported on COVID-19 chest X-ray classification, but most of the previous studies have been conducted on a small set of COVID-19 X-ray images, which created an imbalanced dataset and affected the performance of the deep learning models. In this paper, we propose several image processing techniques to augment COVID-19 X-ray images to generate a large and diverse dataset to boost the performance of deep learning algorithms in detecting the virus from chest X-rays. We also propose innovative and robust deep learning models, based on DenseNet201, VGG16, and VGG19, to detect COVID-19 from a large set of chest X-ray images. A performance evaluation shows that the proposed models outperform all existing techniques to date. Our models achieved 99.62% on the binary classification and 95.48% on the multi-class classification. Based on these findings, we provide a pathway for researchers to develop enhanced models with a balanced dataset that includes the highest available COVID-19 chest X-ray images. This work is of high interest to healthcare providers, as it helps to better diagnose COVID-19 from chest X-rays in less time with higher accuracy.

scholarly journals CheXaid: deep learning assistance for physician diagnosis of tuberculosis using chest x-rays in patients with HIV

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Pranav Rajpurkar ◽  
Chloe O’Connell ◽  
Amit Schechter ◽  
Nishit Asnani ◽  
Jason Li ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Algorithm ◽  
Clinical Information ◽  
Hiv Positive ◽  
X Rays ◽  
Web Based ◽  
X Ray ◽  
Deep Learning Algorithm ◽  
Learning Assistance ◽  
Chest X Ray

Abstract Tuberculosis (TB) is the leading cause of preventable death in HIV-positive patients, and yet often remains undiagnosed and untreated. Chest x-ray is often used to assist in diagnosis, yet this presents additional challenges due to atypical radiographic presentation and radiologist shortages in regions where co-infection is most common. We developed a deep learning algorithm to diagnose TB using clinical information and chest x-ray images from 677 HIV-positive patients with suspected TB from two hospitals in South Africa. We then sought to determine whether the algorithm could assist clinicians in the diagnosis of TB in HIV-positive patients as a web-based diagnostic assistant. Use of the algorithm resulted in a modest but statistically significant improvement in clinician accuracy (p = 0.002), increasing the mean clinician accuracy from 0.60 (95% CI 0.57, 0.63) without assistance to 0.65 (95% CI 0.60, 0.70) with assistance. However, the accuracy of assisted clinicians was significantly lower (p < 0.001) than that of the stand-alone algorithm, which had an accuracy of 0.79 (95% CI 0.77, 0.82) on the same unseen test cases. These results suggest that deep learning assistance may improve clinician accuracy in TB diagnosis using chest x-rays, which would be valuable in settings with a high burden of HIV/TB co-infection. Moreover, the high accuracy of the stand-alone algorithm suggests a potential value particularly in settings with a scarcity of radiological expertise.

scholarly journals An Investigation into the Application of Deep Learning in the Detection and Mitigation of DDOS Attack on SDN Controllers

Technologies ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 14
Author(s):  
James Dzisi Gadze ◽  
Akua Acheampomaa Bamfo-Asante ◽  
Justice Owusu Agyemang ◽  
Henry Nunoo-Mensah ◽  
Kwasi Adu-Boahen Opare
Keyword(s):  
Deep Learning ◽  
Network Architecture ◽  
Learning Algorithm ◽  
Single Point ◽  
Denial Of Service ◽  
Specific Work ◽  
Learning Models ◽  
Ddos Attack ◽  
Deep Learning Algorithm ◽  
Proposed Model

Software-Defined Networking (SDN) is a new paradigm that revolutionizes the idea of a software-driven network through the separation of control and data planes. It addresses the problems of traditional network architecture. Nevertheless, this brilliant architecture is exposed to several security threats, e.g., the distributed denial of service (DDoS) attack, which is hard to contain in such software-based networks. The concept of a centralized controller in SDN makes it a single point of attack as well as a single point of failure. In this paper, deep learning-based models, long-short term memory (LSTM) and convolutional neural network (CNN), are investigated. It illustrates their possibility and efficiency in being used in detecting and mitigating DDoS attack. The paper focuses on TCP, UDP, and ICMP flood attacks that target the controller. The performance of the models was evaluated based on the accuracy, recall, and true negative rate. We compared the performance of the deep learning models with classical machine learning models. We further provide details on the time taken to detect and mitigate the attack. Our results show that RNN LSTM is a viable deep learning algorithm that can be applied in the detection and mitigation of DDoS in the SDN controller. Our proposed model produced an accuracy of 89.63%, which outperformed linear-based models such as SVM (86.85%) and Naive Bayes (82.61%). Although KNN, which is a linear-based model, outperformed our proposed model (achieving an accuracy of 99.4%), our proposed model provides a good trade-off between precision and recall, which makes it suitable for DDoS classification. In addition, it was realized that the split ratio of the training and testing datasets can give different results in the performance of a deep learning algorithm used in a specific work. The model achieved the best performance when a split of 70/30 was used in comparison to 80/20 and 60/40 split ratios.

scholarly journals Ensemble Deep Learning for Cervix Image Selection toward Improving Reliability in Automated Cervical Precancer Screening

Diagnostics ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 451 ◽  
Author(s):  
Peng Guo ◽  
Zhiyun Xue ◽  
Zac Mtema ◽  
Karen Yeates ◽  
Ophira Ginsburg ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Algorithm ◽  
Binary Classification ◽  
Digital Camera ◽  
Deep Learning Algorithm ◽  
Average Accuracy ◽  
Acceptable Quality ◽  
Cervical Precancer ◽  
One Class Classification ◽  
Learning Architectures

Automated Visual Examination (AVE) is a deep learning algorithm that aims to improve the effectiveness of cervical precancer screening, particularly in low- and medium-resource regions. It was trained on data from a large longitudinal study conducted by the National Cancer Institute (NCI) and has been shown to accurately identify cervices with early stages of cervical neoplasia for clinical evaluation and treatment. The algorithm processes images of the uterine cervix taken with a digital camera and alerts the user if the woman is a candidate for further evaluation. This requires that the algorithm be presented with images of the cervix, which is the object of interest, of acceptable quality, i.e., in sharp focus, with good illumination, without shadows or other occlusions, and showing the entire squamo-columnar transformation zone. Our prior work has addressed some of these constraints to help discard images that do not meet these criteria. In this work, we present a novel algorithm that determines that the image contains the cervix to a sufficient extent. Non-cervix or other inadequate images could lead to suboptimal or wrong results. Manual removal of such images is labor intensive and time-consuming, particularly in working with large retrospective collections acquired with inadequate quality control. In this work, we present a novel ensemble deep learning method to identify cervix images and non-cervix images in a smartphone-acquired cervical image dataset. The ensemble method combined the assessment of three deep learning architectures, RetinaNet, Deep SVDD, and a customized CNN (Convolutional Neural Network), each using a different strategy to arrive at its decision, i.e., object detection, one-class classification, and binary classification. We examined the performance of each individual architecture and an ensemble of all three architectures. An average accuracy and F-1 score of 91.6% and 0.890, respectively, were achieved on a separate test dataset consisting of more than 30,000 smartphone-captured images.

scholarly journals Evaluation of Scalability and Degree of Fine-Tuning of Deep Convolutional Neural Networks for COVID-19 Screening on Chest X-ray Images Using Explainable Deep-Learning Algorithm

2020 ◽  
Vol 10 (4) ◽  
pp. 213 ◽  
Author(s):  
Ki-Sun Lee ◽  
Jae Young Kim ◽  
Eun-tae Jeon ◽  
Won Suk Choi ◽  
Nan Hee Kim ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Strategies ◽  
Transfer Learning ◽  
Learning Algorithm ◽  
Fine Tuning ◽  
Deep Convolutional Neural Networks ◽  
X Ray ◽  
Backbone Network ◽  
Deep Learning Algorithm ◽  
Chest X Ray

According to recent studies, patients with COVID-19 have different feature characteristics on chest X-ray (CXR) than those with other lung diseases. This study aimed at evaluating the layer depths and degree of fine-tuning on transfer learning with a deep convolutional neural network (CNN)-based COVID-19 screening in CXR to identify efficient transfer learning strategies. The CXR images used in this study were collected from publicly available repositories, and the collected images were classified into three classes: COVID-19, pneumonia, and normal. To evaluate the effect of layer depths of the same CNN architecture, CNNs called VGG-16 and VGG-19 were used as backbone networks. Then, each backbone network was trained with different degrees of fine-tuning and comparatively evaluated. The experimental results showed the highest AUC value to be 0.950 concerning COVID-19 classification in the experimental group of a fine-tuned with only 2/5 blocks of the VGG16 backbone network. In conclusion, in the classification of medical images with a limited number of data, a deeper layer depth may not guarantee better results. In addition, even if the same pre-trained CNN architecture is used, an appropriate degree of fine-tuning can help to build an efficient deep learning model.

scholarly journals An Effective Convolutional Neural Network Model for the Early Detection of COVID-19 Using Chest X-ray Images

2021 ◽  
Vol 11 (21) ◽  
pp. 10301
Author(s):  
Muhammad Shoaib Farooq ◽  
Attique Ur Rehman ◽  
Muhammad Idrees ◽  
Muhammad Ahsan Raza ◽  
Jehad Ali ◽  
...  
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Real World ◽  
Early Stage ◽  
Binary Classification ◽  
X Rays ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray

COVID-19 has been difficult to diagnose and treat at an early stage all over the world. The numbers of patients showing symptoms for COVID-19 have caused medical facilities at hospitals to become unavailable or overcrowded, which is a major challenge. Studies have recently allowed us to determine that COVID-19 can be diagnosed with the aid of chest X-ray images. To combat the COVID-19 outbreak, developing a deep learning (DL) based model for automated COVID-19 diagnosis on chest X-ray is beneficial. In this research, we have proposed a customized convolutional neural network (CNN) model to detect COVID-19 from chest X-ray images. The model is based on nine layers which uses a binary classification method to differentiate between COVID-19 and normal chest X-rays. It provides COVID-19 detection early so the patients can be admitted in a timely fashion. The proposed model was trained and tested on two publicly available datasets. Cross-dataset studies are used to assess the robustness in a real-world context. Six hundred X-ray images were used for training and two hundred X-rays were used for validation of the model. The X-ray images of the dataset were preprocessed to improve the results and visualized for better analysis. The developed algorithm reached 98% precision, recall and f1-score. The cross-dataset studies also demonstrate the resilience of deep learning algorithms in a real-world context with 98.5 percent accuracy. Furthermore, a comparison table was created which shows that our proposed model outperforms other relative models in terms of accuracy. The quick and high-performance of our proposed DL-based customized model identifies COVID-19 patients quickly, which is helpful in controlling the COVID-19 outbreak.

scholarly journals Development of Deep Learning Algorithm using Convolutional Neural Network for Medical Imaging

2020 ◽  
Vol 9 (3) ◽  
pp. 139-142
Keyword(s):  
Deep Learning ◽  
Medical Imaging ◽  
Brain Tumors ◽  
Learning Algorithm ◽  
Internal Organs ◽  
Clinical Images ◽  
Methodology Development ◽  
Deep Learning Algorithm ◽  
Graphical Illustration ◽  
Research Analysis

Medical imaging is the procedure and approach of formulating graphic models of the peculiarity of a body system for medical investigation and treatment, and also graphical illustration of the function of several internal organs or structures. To identify the affected tissues of the brain in a case of brain tumors, it is important to get high precision and accuracy to locate exact pixels. Manual analysis may be erroneous and so it is important to use deep learning image segmentation technique. Segmentation of graphic is the technique of dividing a graphic in to several group of pixels. The earlier objective of the segmentation is actually to produce details much easier and enhance the manifestation of clinical images into significant content. Segmentation is a complicated activity due to the excessive variability in the graphics. The computational intelligence is modern way for application automation. Existing studies shows need of deep learning research for fast and accurate medical imaging solutions. Hence, this paper presents the CNN framework (for an analysis of brain tumors) as a base for further research methodology development. The paper also provides a pilot research analysis that can further be used to develop improved precision and visibility

scholarly journals Performance of a deep learning CNN model for the automated detection of 13 common conditions on Chest X-rays

2021 ◽  
Author(s):  
Tirupathi Karthik ◽  
Vijayalakshmi Kasiraman ◽  
Bhavani Paski ◽  
Kashyap Gurram ◽  
Amit Talwar ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Algorithm ◽  
Delayed Diagnosis ◽  
Cost Effective ◽  
Radiology Workflow ◽  
X Rays ◽  
Term Care ◽  
X Ray ◽  
Intelligence System ◽  
Deep Learning Algorithm

Background and aims: Chest X-rays are widely used, non-invasive, cost effective imaging tests. However, the complexity of interpretation and global shortage of radiologists have led to reporting backlogs, delayed diagnosis and a compromised quality of care. A fully automated, reliable artificial intelligence system that can quickly triage abnormal images for urgent radiologist review would be invaluable in the clinical setting. The aim was to develop and validate a deep learning Convoluted Neural Network algorithm to automate the detection of 13 common abnormalities found on Chest X-rays. Method: In this retrospective study, a VGG 16 deep learning model was trained on images from the Chest-ray 14, a large publicly available Chest X-ray dataset, containing over 112,120 images with annotations. Images were split into training, validation and testing sets and trained to identify 13 specific abnormalities. The primary performance measures were accuracy and precision. Results: The model demonstrated an overall accuracy of 88% in the identification of abnormal X-rays and 87% in the detection of 13 common chest conditions with no model bias. Conclusion: This study demonstrates that a well-trained deep learning algorithm can accurately identify multiple abnormalities on X-ray images. As such models get further refined, they can be used to ease radiology workflow bottlenecks and improve reporting efficiency. Napier Healthcare’s team that developed this model consists of medical IT professionals who specialize in AI and its practical application in acute & long-term care settings. This is currently being piloted in a few hospitals and diagnostic labs on a commercial basis.

scholarly journals TRACKING AND PREDICTING COVID-19 RADIOLOGICAL TRAJECTORY USING DEEP LEARNING ON CHEST X-RAYS: INITIAL ACCURACY TESTING

2020 ◽  
Author(s):  
S. Duchesne ◽  
D. Gourdeau ◽  
P. Archambault ◽  
C. Chartrand-Lefebvre ◽  
L. Dieumegarde ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Algorithm ◽  
Roc Curves ◽  
Quantitative Information ◽  
Lung Lesion ◽  
Imaging Features ◽  
X Rays ◽  
Disease Trajectory ◽  
Deep Learning Algorithm ◽  
Deep Learning Features

ABSTRACTBackgroundDecision scores and ethically mindful algorithms are being established to adjudicate mechanical ventilation in the context of potential resources shortage due to the current onslaught of COVID-19 cases. There is a need for a reproducible and objective method to provide quantitative information for those scores.PurposeTowards this goal, we present a retrospective study testing the ability of a deep learning algorithm at extracting features from chest x-rays (CXR) to track and predict radiological evolution.Materials and MethodsWe trained a repurposed deep learning algorithm on the CheXnet open dataset (224,316 chest X-ray images of 65,240 unique patients) to extract features that mapped to radiological labels. We collected CXRs of COVID-19-positive patients from two open-source datasets (last accessed on April 9, 2020)(Italian Society for Medical and Interventional Radiology and MILA). Data collected form 60 pairs of sequential CXRs from 40 COVID patients (mean age ± standard deviation: 56 ± 13 years; 23 men, 10 women, seven not reported) and were categorized in three categories: “Worse”, “Stable”, or “Improved” on the basis of radiological evolution ascertained from images and reports. Receiver operating characteristic analyses, Mann-Whitney tests were performed.ResultsOn patients from the CheXnet dataset, the area under ROC curves ranged from 0.71 to 0.93 for seven imaging features and one diagnosis. Deep learning features between “Worse” and “Improved” outcome categories were significantly different for three radiological signs and one diagnostic (“Consolidation”, “Lung Lesion”, “Pleural effusion” and “Pneumonia”; all P < 0.05). Features from the first CXR of each pair could correctly predict the outcome category between “Worse” and “Improved” cases with 82.7% accuracy.ConclusionCXR deep learning features show promise for classifying the disease trajectory. Once validated in studies incorporating clinical data and with larger sample sizes, this information may be considered to inform triage decisions.

scholarly journals Deep Learning Approach for COVID-19 Diagnosis Using X-Ray Images

2020 ◽  
Author(s):  
Muntasir Al-Asfoor
Keyword(s):  
Deep Learning ◽  
Learning Algorithm ◽  
Normal Subjects ◽  
Learning Approach ◽  
Computer Aided Detection ◽  
X Ray ◽  
Deep Learning Algorithm ◽  
Chest X Ray ◽  
The Times

Abstract During the times of pandemics, faster diagnosis plays a key role in the response efforts to contain the disease as well as reducing its spread. Computer-aided detection would save time and increase the quality of diagnosis in comparison with manual human diagnosis. Artificial Intelligence (AI) through deep learning is considered as a reliable method to design such systems. In this research paper, an AI based diagnosis approach has been suggested to tackle the COVID-19 pandemic. The proposed system employs a deep learning algorithm on chest x-ray images to detect the infected subjects. An enhanced Convolutional Neural Network (CNN) architecture has been designed with 22 layers which is then trained over a chest x-ray dataset. More after, a classification component has been introduced to classify the x-ray images into two categories (Covid-19 and not Covid-19) of infection. The system has been evaluated through a series of observations and experimentation. The experimental results have shown a promising performance in terms of accuracy. The system has diagnosed Covid-19 with accuracy of 95.7% and normal subjects with accuracy of 93.1 while it showed 96.7 accuracy on Pneumonia.

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