scholarly journals Automatic Segmentation of Coronary Arteries in X-ray Angiograms using Multiscale Analysis and Artificial Neural Networks

2019 ◽  
Vol 9 (24) ◽  
pp. 5507 ◽  
Author(s):  
Fernando Cervantes-Sanchez ◽  
Ivan Cruz-Aceves ◽  
Arturo Hernandez-Aguirre ◽  
Martha Alicia Hernandez-Gonzalez ◽  
Sergio Eduardo Solorio-Meza

This paper presents a novel method for the automatic segmentation of coronary arteries in X-ray angiograms, based on multiscale analysis and neural networks. The multiscale analysis is performed by using Gaussian filters in the spatial domain and Gabor filters in the frequency domain, which are used as inputs by a multilayer perceptron (MLP) for the enhancement of vessel-like structures. The optimal design of the MLP is selected following a statistical comparative analysis, using a training set of 100 angiograms, and the area under the ROC curve ( A z ) for assessment of the detection performance. The detection results of the proposed method are compared with eleven state-of-the-art blood vessel enhancement methods, obtaining the highest performance of A z = 0.9775 , with a test set of 30 angiograms. The database of 130 X-ray coronary angiograms has been outlined by a specialist and approved by a medical ethics committee. On the other hand, the vessel extraction technique was selected from fourteen binary classification algorithms applied to the multiscale filter response. Finally, the proposed segmentation method is compared with twelve state-of-the-art vessel segmentation methods in terms of six binary evaluation metrics, where the proposed method provided the most accurate coronary arteries segmentation with a classification rate of 0.9698 and Dice coefficient of 0.6857 , using the test set of angiograms. In addition to the experimental results, the performance in the detection and segmentation steps of the proposed method have also shown that it can be highly suitable for systems that perform computer-aided diagnosis in X-ray imaging.

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Ivan Cruz-Aceves ◽  
Fernando Cervantes-Sanchez ◽  
Maria Susana Avila-Garcia

The accurate and efficient segmentation of coronary arteries in X-ray angiograms represents an essential task for computer-aided diagnosis. This paper presents a new multiscale Gaussian-matched filter (MGMF) based on artificial neural networks. The proposed method consists of two different stages. In the first stage, MGMF is used for detecting vessel-like structures while reducing image noise. The results of MGMF are compared with those obtained using six GMF-based detection methods in terms of the area (Az) under the receiver operating characteristic (ROC) curve. In the second stage, ten thresholding methods of the state of the art are compared in order to classify the magnitude of the multiscale Gaussian response into vessel and nonvessel pixels, respectively. The accuracy measure is used to analyze the segmentation methods, by comparing the results with a set of 100 X-ray coronary angiograms, which were outlined by a specialist to form the ground truth. Finally, the proposed method is compared with seven state-of-the-art vessel segmentation methods. The vessel detection results using the proposed MGMF method achieved an Az=0.9357 with a training set of 50 angiograms and Az=0.9362 with the test set of 50 images. In addition, the segmentation results using the intraclass variance thresholding method provided a segmentation accuracy of 0.9568 with the test set of coronary angiograms.


Author(s):  
Jorge F. Lazo ◽  
Aldo Marzullo ◽  
Sara Moccia ◽  
Michele Catellani ◽  
Benoit Rosa ◽  
...  

Abstract Purpose Ureteroscopy is an efficient endoscopic minimally invasive technique for the diagnosis and treatment of upper tract urothelial carcinoma. During ureteroscopy, the automatic segmentation of the hollow lumen is of primary importance, since it indicates the path that the endoscope should follow. In order to obtain an accurate segmentation of the hollow lumen, this paper presents an automatic method based on convolutional neural networks (CNNs). Methods The proposed method is based on an ensemble of 4 parallel CNNs to simultaneously process single and multi-frame information. Of these, two architectures are taken as core-models, namely U-Net based in residual blocks ($$m_1$$ m 1 ) and Mask-RCNN ($$m_2$$ m 2 ), which are fed with single still-frames I(t). The other two models ($$M_1$$ M 1 , $$M_2$$ M 2 ) are modifications of the former ones consisting on the addition of a stage which makes use of 3D convolutions to process temporal information. $$M_1$$ M 1 , $$M_2$$ M 2 are fed with triplets of frames ($$I(t-1)$$ I ( t - 1 ) , I(t), $$I(t+1)$$ I ( t + 1 ) ) to produce the segmentation for I(t). Results The proposed method was evaluated using a custom dataset of 11 videos (2673 frames) which were collected and manually annotated from 6 patients. We obtain a Dice similarity coefficient of 0.80, outperforming previous state-of-the-art methods. Conclusion The obtained results show that spatial-temporal information can be effectively exploited by the ensemble model to improve hollow lumen segmentation in ureteroscopic images. The method is effective also in the presence of poor visibility, occasional bleeding, or specular reflections.


Author(s):  
Aleksei Aleksandrovich Rumyantsev ◽  
Farkhad Mansurovich Bikmuratov ◽  
Nikolai Pavlovich Pashin

The subject of this research is medical chest X-ray images. After fundamental pre-processing, the accumulated database of such images can be used for training deep convolutional neural networks that have become one of the most significant innovations in recent years. The trained network carries out preliminary binary classification of the incoming images and serve as an assistant to the radiotherapist. For this purpose, it is necessary to train the neural network to carefully minimize type I and type II errors. Possible approach towards improving the effectiveness of application of neural networks, by the criteria of reducing computational complexity and quality of image classification, is the auxiliary approaches: image pre-processing and preliminary calculation of entropy of the fragments. The article provides the algorithm for X-ray image pre-processing, its fragmentation, and calculation of the entropy of separate fragments. In the course of pre-processing, the region of lungs and spine is selected, which comprises approximately 30-40% of the entire image. Then the image is divided into the matrix of fragments, calculating the entropy of separate fragments in accordance with Shannon’s formula based pm the analysis of individual pixels. Determination of the rate of occurrence of each of the 255 colors allows calculating the total entropy. The use of entropy for detecting pathologies is based on the assumption that its values differ for separate fragments and overall picture of its distribution between the images with the norm and pathologies. The article analyzes the statistical values: standard deviation of error, dispersion. A fully connected neural network is used for determining the patterns in distribution of entropy and its statistical characteristics on various fragments of the chest X-ray image.


2014 ◽  
Vol 721 ◽  
pp. 783-787
Author(s):  
Shao Hu Peng ◽  
Hyun Do Nam ◽  
Yan Fen Gan ◽  
Xiao Hu

Automatic segmentation of the line-like regions plays a very important role in the automatic recognition system, such as automatic cracks recognition in X-ray images, automatic vessels segmentation in CT images. In order to automatically segment line-like regions in the X-ray/CT images, this paper presents a robust line filter based on the local gray level variation and multiscale analysis. The proposed line filter makes usage of the local gray level and its local variation to enhance line-like regions in the X-ray/CT image, which can well overcome the problems of the image noises and non-uniform intensity of the images. For detecting various sizes of line-like regions, an image pyramid is constructed based on different neighboring distances, which enables the proposed filter to analyze different sizes of regions independently. Experimental results showed that the proposed line filter can well segment various sizes of line-like regions in the X-ray/CT images, which are with image noises and non-uniform intensity problems.


2016 ◽  
Vol 22 (2) ◽  
pp. 44-56 ◽  
Author(s):  
Jan-Vidar Ølberg ◽  
Morten Goodwin

Abstract Teeth are some of the most resilient tissues of the human body. Because of their placement, teeth often yield intact indicators even when other metrics, such as finger prints and DNA, are missing. Forensics on dental identification is now mostly manual work which is time and resource intensive. Systems for automated human identification from dental X-ray images have the potential to greatly reduce the necessary efforts spent on dental identification, but it requires a system with high stability and accuracy so that the results can be trusted. This paper proposes a new system for automated dental X-ray identification. The scheme extracts tooth and dental work contours from the X-ray images and uses the Hausdorff-distance measure for ranking persons. This combination of state-of-the-art approaches with a novel lowest cost path-based method for separating a dental X-ray image into individual teeth, is able to achieve comparable and better results than what is available in the literature. The proposed scheme is fully functional and is used to accurately identify people within a real dental database. The system is able to perfectly separate 88.7% of the teeth in the test set. Further, in the verification process, the system ranks the correct person in top in 86% of the cases, and among the top five in an astonishing 94% of the cases. The approach has compelling potential to significantly reduce the time spent on dental identification.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Abu Mohammed Raisuddin ◽  
Elias Vaattovaara ◽  
Mika Nevalainen ◽  
Marko Nikki ◽  
Elina Järvenpää ◽  
...  

AbstractWrist Fracture is the most common type of fracture with a high incidence rate. Conventional radiography (i.e. X-ray imaging) is used for wrist fracture detection routinely, but occasionally fracture delineation poses issues and an additional confirmation by computed tomography (CT) is needed for diagnosis. Recent advances in the field of Deep Learning (DL), a subfield of Artificial Intelligence (AI), have shown that wrist fracture detection can be automated using Convolutional Neural Networks. However, previous studies did not pay close attention to the difficult cases which can only be confirmed via CT imaging. In this study, we have developed and analyzed a state-of-the-art DL-based pipeline for wrist (distal radius) fracture detection—DeepWrist, and evaluated it against one general population test set, and one challenging test set comprising only cases requiring confirmation by CT. Our results reveal that a typical state-of-the-art approach, such as DeepWrist, while having a near-perfect performance on the general independent test set, has a substantially lower performance on the challenging test set—average precision of 0.99 (0.99–0.99) versus 0.64 (0.46–0.83), respectively. Similarly, the area under the ROC curve was of 0.99 (0.98–0.99) versus 0.84 (0.72–0.93), respectively. Our findings highlight the importance of a meticulous analysis of DL-based models before clinical use, and unearth the need for more challenging settings for testing medical AI systems.


2021 ◽  
Vol 27 (3) ◽  
pp. 146045822110330
Author(s):  
Diedre Carmo ◽  
Israel Campiotti ◽  
Lívia Rodrigues ◽  
Irene Fantini ◽  
Gustavo Pinheiro ◽  
...  

The COVID-19 pandemic generated research interest in automated models to perform classification and segmentation from medical imaging of COVID-19 patients, However, applications in real-world scenarios are still needed. We describe the development and deployment of COVID-19 decision support and segmentation system. A partnership with a Brazilian radiologist consortium, gave us access to 1000s of labeled computed tomography (CT) and X-ray images from São Paulo Hospitals. The system used EfficientNet and EfficientDet networks, state-of-the-art convolutional neural networks for natural images classification and segmentation, in a real-time scalable scenario in communication with a Picture Archiving and Communication System (PACS). Additionally, the system could reject non-related images, using header analysis and classifiers. We achieved CT and X-ray classification accuracies of 0.94 and 0.98, respectively, and Dice coefficient for lung and covid findings segmentations of 0.98 and 0.73, respectively. The median response time was 7 s for X-ray and 4 min for CT.


2020 ◽  
Author(s):  
Antonios Makris ◽  
Ioannis Kontopoulos ◽  
Konstantinos Tserpes

AbstractThe COVID-19 pandemic in 2020 has highlighted the need to pull all available resources towards the mitigation of the devastating effects of such “Black Swan” events. Towards that end, we investigated the option to employ technology in order to assist the diagnosis of patients infected by the virus. As such, several state-of-the-art pre-trained convolutional neural networks were evaluated as of their ability to detect infected patients from chest X-Ray images. A dataset was created as a mix of publicly available X-ray images from patients with confirmed COVID-19 disease, common bacterial pneumonia and healthy individuals. To mitigate the small number of samples, we employed transfer learning, which transfers knowledge extracted by pre-trained models to the model to be trained. The experimental results demonstrate that the classification performance can reach an accuracy of 95% for the best two models.


2017 ◽  
Vol 23 (S1) ◽  
pp. 984-985
Author(s):  
Tia Plautz ◽  
Rosanne Boudreau ◽  
Jian-Hua Chen ◽  
Axel Ekman ◽  
Mark LeGros ◽  
...  

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