scholarly journals Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China

2019 ◽  
Vol 9 (6) ◽  
pp. 1078 ◽  
Author(s):  
Quancai Peng ◽  
Jinming Song ◽  
Xuegang Li ◽  
Huamao Yuan ◽  
Guang Yang
Keyword(s):  
North China ◽  
Solid Phase ◽  
Total Concentration ◽  
Jiaozhou Bay ◽  
Aquatic Organisms ◽  
Individual Risk ◽  
Scientific Management ◽  
Pharmaceutically Active Compounds ◽  
Long Distance ◽  
Active Compounds

The occurrence and distribution of 110 pharmaceutically active compounds (PhACs) were investigated in snow near Jiaozhou Bay (JZB), North China. All target substances were analyzed using solid phase extraction followed by liquid chromatography coupled to tandem mass spectrometry.A total of 38 compounds were detected for the first time in snow, including 23 antibiotics, eight hormones, three nonsteroidal anti-inflammatory drugs, two antipsychotics, one beta-adrenergic receptor and one hypoglycemic drug. The total concentration of PhACs in snow ranged from 52.80 ng/L to 1616.02 ng/L. The compounds found at the highest mean concentrations included tetracycline (125.81 ng/L), desacetylcefotaxime (17.73 ng/L), ronidazole (8.79 ng/L) and triamcinolone diacetate (2.84 ng/L). The contribution of PhACs in the vicinity of JZB to the PhACs in the snow is far greater than the contribution of those transmitted over a long distance. PhACs are mainly derived from drugs applied to local humans and animals. Based on the individual risk quotient (RQ) values, tetracycline poses high risks to the relevant aquatic organisms (algae and invertebrates). The rational application and scientific management of PhACs is an effective approach to reduce the ecological risks in JZB.

Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China

2020 ◽  
Vol 266 ◽  
pp. 115245
Author(s):  
Quancai Peng ◽  
Jinming Song ◽  
Xuegang Li ◽  
Huamao Yuan ◽  
Mengtan Liu ◽  
...  
Keyword(s):  
North China ◽  
Surface Sediments ◽  
Jiaozhou Bay ◽  
Pharmaceutically Active Compounds ◽  
Active Compounds

scholarly journals Characterization of Five Portuguese Wastewater Treatment Plants: Removal Efficiency of Pharmaceutical Active Compounds through Conventional Treatment Processes and Environmental Risk

2021 ◽  
Vol 11 (16) ◽  
pp. 7388
Author(s):  
Sofia Silva ◽  
Vitor Vale Cardoso ◽  
Lúcia Duarte ◽  
Rui Neves Carneiro ◽  
Cristina Maria Martins Almeida
Keyword(s):  
Wastewater Treatment ◽  
Surface Waters ◽  
Wastewater Treatment Plants ◽  
Solid Phase ◽  
Aquatic Organisms ◽  
Ultra Performance Liquid Chromatography ◽  
Mass Detection ◽  
Active Compounds ◽  
Treatment Processes ◽  
Removal Efficiencies

Due to the high consumption and incorrect disposal of pharmaceutical active compounds (PhACs), they are recognized as contaminants of emerging concern. Wastewater treatment plants (WWTPs) may be inefficient in removing PhACs, therefore discharging them into surface waters. The removal efficiencies of five WWTPs located in the south of Portugal (Alentejo) were evaluated in 2020. Twenty-six PhACs were analyzed in wastewater influents, effluents, and surface waters, upstream and downstream of the WWTPs by solid-phase extraction (SPE) and ultra-performance liquid chromatography coupled with tandem mass detection (UPLC–MS/MS). The most representative PhACs in influents were acetaminophen, caffeine, naproxen, ibuprofen, and diclofenac with minimum-maximum concentrations of 49–225 µg/L, 26–46 µg/L, 5.9–13 µg/L, 5.2–22 µg/L, and 1.3–2.5 µg/L, respectively. For effluents, it was acetaminophen, caffeine, and diclofenac with minimum-maximum concentrations of 0.054–7.8 µg/L, 0.084–4.8 µg/L, and 0.28–3.3 µg/L, respectively. The highest removal efficiencies were observed for acetaminophen, sulfadiazine, cortisone, testosterone, metoprolol, and propranolol (100%). The lowest removal efficiencies were observed for carbamazepine (2.7%) and diclofenac (−13.2%). The risk quotient of sulfamethoxazole and diclofenac were higher than 1 for receiving waters, indicating they probably pose high risks to aquatic organisms.

scholarly journals Residual pharmaceutically active compounds (PhACs) in aquatic environment – status, toxicity and kinetics: a review

2009 ◽  
Vol 54 (No. 7) ◽  
pp. 295-314 ◽  
Author(s):  
Z.H. Li ◽  
T. Randak
Keyword(s):  
Aquatic Environment ◽  
Current Knowledge ◽  
Influence Factors ◽  
Aquatic Organisms ◽  
Future Research ◽  
Pharmacokinetic Parameters ◽  
Pharmaceutically Active Compounds ◽  
Active Compounds ◽  
Environmental Evaluation ◽  
Detection Techniques

Awareness of residual pharmaceutically active compounds (PhACs) in aquatic ecosystems is growing as research into these pollutants increases and analytical detection techniques improve. For most pharmaceuticals analyzed, the effects on aquatic organisms have usually been investigated by toxic assays in the laboratory. However, little is known about integral analysis of pharmacokinetics in aquatic organisms and specific relations between pharmacokinetic parameters and influence factors. Moreover, the influence of the organisms involved and numerous other external factors complicates development of standard tests for environmental evaluation. Current knowledge about residual pharmaceuticals in the aquatic environment, including status, toxic effects, and pharmacokinetics in aquatic organisms, are reviewed. Based on the above, we identify major gaps in the current knowledge and some directions for future research, such as improvement of techniques to remove residual pharmaceuticals from wastewater, and the establishment of standard pharmaceutical modes of action.

Pharmaceutically Active Compounds Degradation Using Doped TiO2 Functionalized Zeolite Photocatalyst

2018 ◽  
Vol 69 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Monica Ihos ◽  
Corneliu Bogatu ◽  
Carmen Lazau ◽  
Florica Manea ◽  
Rodica Pode
Keyword(s):  
Organic Carbon ◽  
Active Compound ◽  
Uv Spectra ◽  
Pharmaceutically Active Compounds ◽  
Mineralization Process ◽  
Active Compounds ◽  
Spectra Analysis ◽  
Doped Tio2 ◽  
Toc Removal ◽  
Pharmaceutically Active Compound

The aim of this study was the investigation of photocatalytic degradation of pharmaceutically active compounds using doped TiO2 functionalized zeolite photocatalyst. Diclofenac (DCF), a non-steroidal anti-inflammatory drug, that represents a biorefractory micropollutant, was chosen as model of pharmaceutically active compound. The photocatalyst was Z-TiO2-Ag. The concentration of DCF in the working solutions was 10 mg/L,50 mg/L,100 mg/L and 200 mg/L and of photocatalyst 1 g/L in any experiments. The process was monitored by recording the UV spectra of the treated solutions and total organic carbon (TOC) determination. The UV spectra analysis and TOC removal proved that along the advanced degradation of DCF also a mineralization process occurred. The carried out research provided useful information envisaging the treatment of pharmaceutical effluents by photocatalysis.

Methodology of Research in Micropollutants – Heavy Metals

1982 ◽  
Vol 14 (12) ◽  
pp. 107-125 ◽  
Author(s):  
Roland Wollast
Keyword(s):  
Heavy Metals ◽  
Mathematical Models ◽  
Aqueous Phase ◽  
Suspended Matter ◽  
Solid Phase ◽  
Aquatic Organisms ◽  
Biological Processes ◽  
Particulate Phase ◽  
Sources Of Pollution ◽  
Adsorption Desorption

A comparison of the concentration of dissolved and of particulate heavy metals in the aquatic system indicates that these elements are strongly enriched in the suspended matter. The transfer between the aqueous phase and the solid phase may be due to dissolution-precipitation reactions, adsorption-desorption processes or biological processes. When these processes are identified, it is further possible to develop mathematical models which describe the behaviour of these elements. The enrichment of heavy metals in the particulate phase suspended or deposited and in aquatic organisms constitutes a powerful tool in order to evaluate sources of pollution.

Sign in / Sign up

Export Citation Format

Share Document