scholarly journals New Resorbable Membrane Materials for Guided Bone Regeneration

2018 ◽  
Vol 8 (11) ◽  
pp. 2157 ◽  
Author(s):  
You-Young Jo ◽  
Ji-Hyeon Oh
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
Guided Bone Regeneration ◽  
New Materials ◽  
Secondary Surgery ◽  
Aliphatic Polyesters ◽  
Inflammatory Reactions ◽  
Platelet Rich Fibrin ◽  
Clinical Research Data ◽  
Fibrin Membrane

Membranes are used for guided bone regeneration (GBR) in bone defects. Resorbable membranes of collagen or aliphatic polyesters that do not require secondary surgery for removal, unlike non-resorbable membranes, have been marketed for GBR. Platelet rich fibrin membrane and silk-based membranes have recently been assessed as membranes for GBR. Studies have been conducted on resorbable membranes with new materials to improve physical properties and bone regeneration without any adverse inflammatory reactions. However, clinical research data remain limited. More studies are needed to commercialize such membranes.

Simultaneous Implant Placement and Guided Bone Regeneration Using a Platelet-Rich Fibrin Membrane: Case Report

2017 ◽  
Vol 7 (1) ◽  
pp. 19-24
Author(s):  
Yung-Ting Hsu ◽  
Yu-Hsiang Chou ◽  
Tzu-Hsuan Yang ◽  
Yi-Min Wu ◽  
Chiung-Lin Huang ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Platelet Rich Fibrin ◽  
Implant Placement ◽  
Fibrin Membrane

scholarly journals Guided bone regeneration in staged vertical and horizontal bone augmentation using platelet-rich fibrin associated with bone grafts: a retrospective clinical study

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Carlos Alberto Amaral Valladão ◽  
Mabelle Freitas Monteiro ◽  
Julio Cesar Joly
Keyword(s):  
Bone Regeneration ◽  
Bone Grafts ◽  
Bone Defects ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Bone Augmentation ◽  
Platelet Rich Fibrin ◽  
Link Type ◽  
Retrospective Clinical Study ◽  
Bone Gain

Abstract Background The use of guided bone regeneration (GBR) for vertical and horizontal bone gain is a predictable approach to correct the bone defects before implant installation; however, the use of different protocols is associated with different clinical results. It is suggested that platelet-rich fibrin (PRF) could improve the outcomes of regenerative procedures. Thus, this study aimed to describe the bone gain associated with GBR procedures combining membranes, bone grafts, and PRF for vertical and horizontal bone augmentation. Materials and methods Eighteen patients who needed vertical or horizontal bone regeneration before installing dental implants were included in the study. The horizontal bone defects were treated with a GBR protocol that includes the use of a mixture of particulate autogenous and xenogenous grafts in the proportion of 1:1, injectable form of PRF (i-PRF) to agglutinate the graft, an absorbable collagen membrane covering the regenerated region, and leukocyte PRF (L-PRF) membrane covering the GBR membrane. The vertical bone defects were treated with the same grafted mixture protected by a titanium-reinforced non-resorbable high-density polytetrafluoroethylene (d-PTFE-Ti) membrane and covered by L-PRF. The bone gain was measured using a cone-beam computed tomography at baseline and after a period of 7.5 (± 1.0) months. Results All patients underwent surgery to install implants after this regenerative protocol. The GBR produces an increase in bone thickness (p < 0.001) and height (p < 0.005) after treatment, with a bone gain of 5.9 ± 2.4 for horizontal defects and 5.6 ± 2.6 for vertical defects. In horizontal defects, the gain was higher in the maxilla than in mandible (p = 0.014) and in anterior than the posterior region (p = 0.033). No differences related to GBR location were observed in vertical defects (p > 0.05). Conclusion GBR associated with a mixture of particulate autogenous and xenogenous grafts and i-PRF is effective for vertical and horizontal bone augmentation in maxillary and mandibular regions, permitting sufficient bone gain to future implant placement. Trial registration REBEC, RBR-3CSG3J. Date of registration—19 July 2019, retrospectively registered. http://www.ensaiosclinicos.gov.br/rg/RBR-3csg3j/

scholarly journals Localized Bone Augmentation and Implant Site Development-Review with a case

2019 ◽  
Vol 2 (1) ◽  
pp. 47-52
Author(s):  
Pramod Kumar Koirala ◽  
S Pradhan ◽  
RS Gorkhali
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
Bone Augmentation ◽  
Titanium Mesh ◽  
Platelet Rich Fibrin ◽  
Osteogenic Cells ◽  
Site Development ◽  
Membrane Exposure ◽  
Regeneration Of Bone ◽  
Fibrin Membrane

Guided bone regeneration (GBR) has been used for the regeneration of bone in conjunction with the placement of dental implants, for augmentation of resorbed alveolar crests, and to treat localized ridge deformities. It is based on the principle of protecting bone regeneration against overgrowth of tissues formed by rapidly proliferating non-osteogenic cells. In this case, the space created by the Titanium mesh supported platelet rich fibrin membrane was filled by tissues with features of newly formed bone. No residual bone defects were observed and an increase of the alveolar width and height was observed. No untoward effects on bone regeneration were observed except membrane exposure after 4 and 1/2months. This case shows a satisfactory result concerning GBR technique or implant site development.  

scholarly journals Guided bone regeneration of chronic non‐contained bone defects using a volume stable porous block TiO2 scaffold: An experimental in vivo study

2021 ◽  
Author(s):  
Minh Khai Le Thieu ◽  
Håvard Jostein Haugen ◽  
Javier Sanz‐Esporrin ◽  
Mariano Sanz ◽  
Ståle Petter Lyngstadaas ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
Guided Bone Regeneration ◽  
In Vivo Study ◽  
Porous Block

scholarly journals Augmentation of Peri-implant Bone Defects with Different Bone Grafts and Guided Bone Regeneration:

2006 ◽  
Vol 15 (3) ◽  
pp. 82-88 ◽  
Author(s):  
Weijian Zhong ◽  
Guowu Ma ◽  
Yi Wang ◽  
Ryo Tamamura ◽  
Jing Xiao
Keyword(s):  
Bone Regeneration ◽  
Bone Grafts ◽  
Bone Defects ◽  
Guided Bone Regeneration

Guided Bone Regeneration in Calvarial Bone Defects Using Polytetrafluoroethylene Membranes

1995 ◽  
Vol 32 (4) ◽  
pp. 311-317 ◽  
Author(s):  
Carles Bosch ◽  
Birte Melsen ◽  
Karin Vargervik
Keyword(s):  
Bone Regeneration ◽  
Bone Defect ◽  
Dura Mater ◽  
Bone Defects ◽  
Guided Bone Regeneration ◽  
Parietal Bone ◽  
Bony Defect ◽  
Calvarial Bone ◽  
Double Membrane ◽  
Single Membrane

Guided bone regeneration is defined as controlled stimulation of new bone formation in a bony defect, either by osteogenesis, osteoinduction, or osteoconduction, re-establishing both structural and functional characteristics. Bony defects may be found as a result of congenital anomalies, trauma, neoplasms, or infectious conditions. Such conditions are often associated with severe functional and esthetic problems. Corrective treatment is often complicated by limitations in tissue adaptations. The aim of the investigation was to compare histologically the amount of bone formed in an experimentally created parietal bone defect protected with one or two polytetrafluoroethylene membranes with a contralateral control defect. A bony defect was created bilaterally in the parietal bone lateral to the sagittal suture in 29 6-month-old male Wistar rats. The animals were divided into two groups: (1) In the double membrane group (n=9), the left experimental bone defect was protected by an outer polytetrafluoroethylene membrane under the periosteum and parietal muscles and an inner membrane between the dura mater and the parietal bone. (2) In the single membrane group (n=20), only the outer membrane was placed. The right defect was not covered with any membrane and served as control. The animals were killed after 30 days. None of the control defects demonstrated complete or partial bone regeneration. In the single membrane group, the experimental site did not regenerate in 15 animals, partially in four, and completely in one. In the double membrane group, six of the experimental defects had complete closure with bone, two had partial closure, and one no closure. The use of two membranes protecting the bone edges of the parietal defect from the overlying tissues and underlying brain enhanced bone regeneration in experimental calvarial bone defects. The biologic role of the dura mater may not be of critical importance in new bone regeneration in these calvarial bone defects.

scholarly journals Effects of Platelet-Rich Fibrin on Hard Tissue Healing: A Histomorphometric Crossover Trial in Sheep

Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1695
Author(s):  
Esra Ondur ◽  
Nilufer Bolukbasi Balcioglu ◽  
Merva Soluk Tekkesin ◽  
Ozlem Guzel ◽  
Selim Ersanli
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
Collagen Membrane ◽  
Bovine Bone ◽  
Graft Material ◽  
Hard Tissue ◽  
Platelet Rich Fibrin ◽  
Tissue Healing ◽  
Significant Difference ◽  
Time Point

Bone defects lead to aesthetic and functional losses, causing dental rehabilitation to be more difficult. The objective of this work is to histologically assess the hard tissue healing of bone defects filled with platelet-rich fibrin (PRF) alone or as an adjuvant for mixing with and covering anorganic bovine bone (ABB), compared to ABB covered with a resorbable collagen membrane (CM). This study was designed as a crossover animal study. Four 5-mm tibia defects, 5 mm apart from each other, were surgically created on the tibias of 6 sheep. The defects were randomly filled with ABB + CM; PRF alone; ABB+PRF; or were left empty. The animals were euthanized on days 10, 20, and 40 post-operatively. No group showed any signs of bone necrosis. Inflammation was observed in 2 control and 3 test defects with no statistically significant difference between groups at each time point. The ABB + CM and ABB + PRF groups experienced the highest bone regeneration ratios. No differences between the empty-defect and PRF groups were observed in regard to bone regeneration. No statistical difference was observed between the ABB+PRF and ABB + CM groups in regard to bone regeneration and the amount of residual graft material at each time point. The use of PRF should be preferred due to its autogenous origin, low cost, and ease of use.

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