scholarly journals Reliability and Validity of the Ground Reaction Force Asymmetric Index at Seat-Off as a Measure of Lower Limb Functional Muscle Strength: A Preliminary Study

2021 ◽  
Vol 11 (14) ◽  
pp. 6527
Author(s):  
Ae-Ryoung Kim ◽  
Dougho Park ◽  
Yang-Soo Lee
Keyword(s):  
Muscle Strength ◽  
Grip Strength ◽  
Ground Reaction Force ◽  
Walking Speed ◽  
Reaction Force ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Intrarater Reliability ◽  
Hand Grip ◽  
The Right

This study examined the reliability of the newly developed ground reaction force asymmetry index (GRF AI) at seat-off using a low-cost force plate and the validity of this new test by comparing it with other muscle strength-measuring methods and walking speed. This study was a cross-sectional design in general hospital setting. A convenience sample of 47 community-dwelling adults aged ≥40 years was performed. GRF AI is the measurement value obtained by shifting the weight to the right and left while performing sit-to-stand (STS). GRF AI assessed using GRF data at seat-off during an STS test with maximal weight shift to the right and left side and repeated 4 weeks later. Hip and knee extensor strength were measured using hand-held dynamometry; hand grip strength and walking speed were measured using a standardized method. Intrasessional intrarater reliability of the right and left side at Sessions 1 and 2 were high (intraclass correlation coefficients [ICC] = 0.947 and 0.974; 0.931 and 0.970, respectively). In addition, the intersessional intrarater reliability of a single test trial (ICC = 0.911 and 0.930) and the mean of three test trials (ICC = 0.965 and 0.979) was also high. There was a low correlation between right-side GRF AI and right hand grip strength (r = 0.268) and between left-side GRF AI and left hand grip strength (r = 0.316). No significant correlations were found between the GRF AI and other parameters. Although the reliability of the GRF AI was high, the validity was poor. To be clinically useful, this test should be further refined by modifying the test protocol.

Abstract 12981: Association of Serum Growth Differentiation Factor-15 With Egfr, Hemoglobin and Sarcopenia in Healthy Community-dwelling Older Females

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Taira Fukuda ◽  
Shigeru Toyoda ◽  
Shichiro Abe ◽  
Teruo Inoue ◽  
Toshiaki Nakajima
Keyword(s):  
Renal Dysfunction ◽  
Grip Strength ◽  
Walking Speed ◽  
Bioelectrical Impedance ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Enzyme Linked Immunosorbent Assay ◽  
Older Individuals ◽  
Hand Grip ◽  
Healthy Community

Introduction: Anemia and sarcopenia with renal dysfunction caused by cytokine imbalance can contribute to decreased quality of life for older individuals. Several studies showed that serum GDF-15 level, a member of the TGF-β cytokine superfamily, was negatively correlated with eGFR. In this study, we examined the association of GDF-15 with eGFR, hemoglobin (Hb) and sarcopenia in healthy community-dwelling older females. Methods: A total of 66 healthy older community-dwelling females (age: 75.8 ± 6.2 years) were enrolled for this study. Skeletal muscle mass index (SMI) by bioelectrical impedance analysis, hand-grip strength and walking speed were assessed, and sarcopenia was evaluated. Serum GDF-15 concentration was determined by enzyme-linked immunosorbent assay. Hb, serum iron (Fe), serum albumin (Alb) and high-sensitive C reactive protein (hsCRP) levels were measured and estimated glomerular filtration rate (eGFR) was evaluated. Multiple linear regression analyses with serum GDF-15 concentration, eGFR and Hb as the dependent variable were performed to identify influencing independent factors. Results: Among the study subjects, 4 (6%) had sarcopenia. The serum GDF-15 level was positively correlated with age (r = 0.486, p < 0.001) and negatively correlated with walking speed (r = -0.363, p = 0.003), but there was no correlation between GDF-15 level and hand-grip strength or SMI. Serum GDF-15 level was also negatively correlated with eGFR (r = -0.535, p < 0.001) and serum Fe level, but had no correlation with hsCRP, Hb or Alb levels. In multiple regression analysis, eGFR and Hb were independent variables to predict serum GDF-15 level, even after adjusting for age and body mass index (eGFR: β = -0.423, p <0.001; Hb: β = -0.363, p=0.004). Serum GDF-15 level was an independent variable to predict eGFR and Hb. Conclusions: Serum GDF-15 level was negatively correlated with eGFR, although it had no correlation with muscle strength or mass. Both Hb and eGFR were predictors for serum GDF-15 concentration in healthy older females. In these community-dwelling older females, renal dysfunction via GDF-15 might be accompanied by anemia, but not sarcopenia.

scholarly journals Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yuan-Yuei Chen ◽  
Yi-Lin Chiu ◽  
Tung-Wei Kao ◽  
Tao-Chun Peng ◽  
Hui-Fang Yang ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Mrna Expression ◽  
Grip Strength ◽  
Muscle Mass ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Cutoff Point ◽  
Walking Distance ◽  
Skeletal Mass ◽  
Hand Grip

Abstract Background Sarcopenia is a multifactorial pathophysiologic condition of skeletal muscle mass and muscle strength associated with aging. However, biomarkers for predicting the occurrence of sarcopenia are rarely discussed in recent studies. The aim of the study was to elucidate the relationship between sarcopenia and several pertinent biomarkers. Methods Using the Gene Expression Omnibus (GEO) profiles of the National Center for Biotechnology Information, the associations between mRNA expression of biomarkers and sarcopenia were explored, including high temperature requirement serine protease A1 (HtrA1), procollagen type III N-terminal peptide (P3NP), apelin, and heat shock proteins 70 (Hsp72). We enrolled 408 community-dwelling adults aged 65 years and older with sarcopenia and nonsarcopenia based on the algorithm proposed by the Asian Working Group for Sarcopenia (AWGS). Muscle strength is identified by hand grip strength using an analogue isometric dynamometer. Muscle mass is estimated by skeletal mass index (SMI) using a bioelectrical impedance analysis. Physical performance is measured by gait speed using 6 m walking distance. The associations between these biomarkers and sarcopenia were determined using receiver operating characteristic (ROC) curve analysis and multivariate regression models. Results From the GEO profiles, the sarcopenia gene set variation analysis score was correlated significantly with the mRNA expression of APLNR (p < 0.001) and HSPA2 (p < 0.001). In our study, apelin was significantly associated with decreased hand grip strength with β values of − 0.137 (95%CI: − 0.229, − 0.046) in men. P3NP and HtrA1 were significantly associated with increased SMI with β values of 0.081 (95%CI: 0.010, 0.153) and 0.005 (95%CI: 0.001, 0.009) in men, respectively. Apelin and HtrA1 were inversely associated with the presence of sarcopenia with an OR of 0.543 (95%CI: 0.397–0.743) and 0.003 (95%CI: 0.001–0.890) after full adjustment. The cutoff point of HtrA1 was associated with the presence of sarcopenia with an OR of 0.254 (95%CI: 0.083–0.778) in men. The cutoff point of apelin was negatively associated with the presence of sarcopenia with an OR of 0.254 (95%CI: 0.083–0.778). Conclusion Our study highlights that P3NP, HtrA, and apelin are useful for diagnosis of sarcopenia in the clinical setting.

scholarly journals Association of Water Intake with Hand Grip Strength in Community-Dwelling Older Adults

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1756
Author(s):  
Hyeonmok Kim ◽  
Sun Hee Beom ◽  
Tae Ho Kim ◽  
Beom-Jun Kim
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Grip Strength ◽  
Water Intake ◽  
Population Based ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Hand Grip ◽  
The Difference

Although recent clinical studies have suggested that water intake enhances muscle mass, its impact on muscle strength remain unclear, especially in older adults. This cross-sectional, population-based study using a representative sample of Koreans investigated the relationship of water intake with hand grip strength (HGS) in 4443 older adults, including 2090 men aged ≥50 years and 2253 postmenopausal women. A digital grip strength dynamometer was used for HGS assessment. Low muscle strength was defined by the Korean-specific HGS cut-off value and adequate water intake was defined according to the Korean dietary reference intakes. In an unadjusted model, water intake was significantly higher in men and women without than with low muscle strength (both p < 0.001), but this difference disappeared after adjustment for confounding variables in both men (p = 0.050) and women (p = 0.245). Similarly, the correlation between water intake and HGS, the difference in HGS depending on adequate water intake status, and the risk of low muscle strength depending on water intake quartile were significant only in the unadjusted model. These data indicate that factors such as age, body size, and resistance exercise contribute to improvements in HGS in older adults, whereas water intake may not.

scholarly journals Relationship between hand grip strength and peak VO2 in community-dwelling elderly outpatients

2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Masamitsu Sugie ◽  
Kazumasa Harada ◽  
Tetsuya Takahashi ◽  
Marina Nara ◽  
Joji Ishikawa ◽  
...  
Keyword(s):  
Grip Strength ◽  
Walking Speed ◽  
Multiple Logistic Regression Analysis ◽  
Peak Oxygen Uptake ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Dominant Hand ◽  
Hand Grip ◽  
Peak Vo2 ◽  
Elderly Outpatients

Background: Hand grip strength and peak oxygen uptake (VO2) are important components of frailty. However, the relationship between these two variables among community-dwelling elderly people is still unclear. The present study aimed to investigate this relationship.Methods: Participants were 190 Japanese community-dwelling elderly outpatients (61 men and 129 women, mean age 78.0 years). Hand grip strength of participants’ dominant hand was measured using a Smedley-type hand dynamometer. Peak VO2 levels were assessed with a cardiopulmonary exercise test. Skeletal muscle mass index (SMI) and usual walking speed were assessed physiologically and physically. Sample size was calculated using G*Power 3.1.9.2.Results: There were significant correlations between hand grip strength and age (r = −0.22), peak VO2 (r = 0.40), SMI (r = 0.51), and usual walking speed (r = 0.29). There were significant differences in age, peak VO2 and SMI after participants were divided into normal and low hand grip strength groups according to the Asian Working Group for Sarcopenia threshold, whether both sexes were combined or considered separately. Multiple logistic regression analysis showed that peak VO2, SMI and age were independent determinants of hand grip strength after adjusting for potential confounders (Exp(B) = 0.871; 0.475; 1.065). Longitudinal analysis after 6 months of exercise training showed the percentage of change in hand grip strength and peak VO2 were correlated positively (r = 0.22) for 92 participants. Conclusion: Peak VO2 is independently associated with hand grip strength among community-dwelling elderly outpatients.  

scholarly journals Malondialdehyde as a Useful Biomarker of Low Hand Grip Strength in Community-Dwelling Stroke Patients

2020 ◽  
Vol 17 (21) ◽  
pp. 7918
Author(s):  
Onchuma Mueangson ◽  
Parinya Vongvaivanichakul ◽  
Kornyok Kamdee ◽  
Chutima Jansakun ◽  
Wanatsanan Chulrik ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Grip Strength ◽  
Muscle Weakness ◽  
Serum Levels ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Stroke Patients ◽  
Post Stroke ◽  
Hand Grip ◽  
Stress Oxidative

The assessment of muscle strength by hand grip strength (HGS) is used to evaluate muscle weakness and wasting among stroke patients. This study aimed to investigate the association of oxidative stress/oxidative damage and inflammatory biomarkers with muscle strength and wasting, as evaluated by HGS, among community-dwelling post-stroke patients. The HGS of both paretic and non-paretic limbs was negatively associated with modified Rankin scale (mRS) values. The serum levels of catalase activity and malondialdehyde (MDA), and plasma tumor necrosis factor (TNF)-α levels were significantly increased in post-stroke patients compared with non-stroke controls. Further analysis highlighted that hydrogen peroxide was positively correlated with HGS in the paretic limbs. Interestingly, an elevated MDA level, excluding advanced age and high mRS, increased the risk of low HGS in the non-paretic limbs of stroke patients. This study suggests that there is a detrimental association between MDA and muscle strength and early muscle wasting among post-stroke patients. Hence, MDA is a potentially useful biomarker of muscle weakness and wasting in post-stroke patients living in the community.

scholarly journals BODY COMPOSITION AND HAND GRIP STRENGTH IN HEALTHY COMMUNITY-DWELLING OLDER ADULTS IN SWEDEN

2015 ◽  
pp. 1-5
Author(s):  
A. Lindblad ◽  
S. Dahlin-Ivanoff ◽  
I. Bosaeus ◽  
E. Rothenberg
Keyword(s):  
Body Composition ◽  
Muscle Strength ◽  
Grip Strength ◽  
Muscle Mass ◽  
Hand Grip Strength ◽  
Community Dwelling ◽  
Consensus Definition ◽  
Hand Grip ◽  
European Consensus ◽  
Community Dwelling Older Adults

Background: Longevity increases worldwide but there are few studies on body composition and hand grip strength in populations over 80 years. Given high prevalence of chronic disease and functional disability in octogenarians, it may be difficult to distinguish effects of ageing from those imposed by disease. The European Consensus definition of sarcopenia recommends using both low muscle mass and function for diagnosis. Objectives: Examine body composition and hand grip strength in a selected group of community-dwelling older adults with high level of functional independence. In addition, longitudinal changes in handgrip strength were examined using previously collected data. Design: Cross-sectional body composition and hand grip strength with a four year retrospective analysis on previously assessed hand grip strength. Setting: Measurements were conducted by home visits. Participants: 102 community-dwelling 83-96 year-olds, 50 % women. Measurements: Hand grip strength was registered by a dynamometer and body composition analysis using bioimpedance spectroscopy. Results: According to European Consensus definition, only 6/102 had normal muscle mass - no men, although 78 % of men and 40 % of women had normal muscle strength. Since previously collected data four years earlier, men had lost strength (p<0.001), while women had not (p=0.202). Conclusions: Subject characteristics and health status support well-preserved body energy, protein stores and muscle strength. Low muscle mass was much more prevalent than low muscle strength. Results may give an indication of what constitutes a healthy body composition in oldest old and could serve as a starting point for reference values on healthy body composition in octogenarians.

Bioimpedance phase angle as a marker of sarcopenia in elderly women with multiple comorbidities

2020 ◽  
Vol 49 ◽  
Author(s):  
D. P. Kurmayev ◽  
S. V. Bulgakova ◽  
N. O. Zakharova
Keyword(s):  
Body Composition ◽  
Grip Strength ◽  
Phase Angle ◽  
Walking Speed ◽  
Elderly Women ◽  
Hand Grip Strength ◽  
Bioimpedance Analysis ◽  
Sit To Stand ◽  
Hand Grip ◽  
Hand Dynamometry

Rationale: The progressive decline in skeletal muscle strength and function during aging can lead to disability and premature death. It is of interest to evaluate the potential of bioimpedance phase angle (PhA) as an instrumental marker of sarcopenia in clinical practice.Aim: To identify an association between the phase angles determined by the bioimpedance analysis of body composition, with functional activity parameters in elderly women with multiple comorbidities.Materials and methods: The study included 146  elderly women (aged 75 to 84  years, mean age 79.44±2.56  years). Assessments consisted of the Charlson comorbidity index, “Vozrast ne pomekha” (Age is not a hindrance) questionnaire, the Barthel index, the sit-to-stand five-repeat test, the standardized 4-meter walking speed test, and bioimpedance analysis of body composition (ABC02, Medass, Russia). Muscle strength parameters were assessed by wrist dynamometry with a mechanical wrist dynamometer. The hand dynamometry index was calculated by dividing the hand grip strength by the patient's squared height. According to the EWGSOP2 guidelines for the critical cur-off for hand dynamometry, the patients were divided into two groups: those with the hand grip strength>16 kg (n=41) and those with<16 kg (n=105).Results: There were significant correlations of PhA with age (r=-0.369; p=0.017), the results of the screening questionnaire “Vozrast ne pomekha” (Age is not a hindrance) (r=-0.359; p=0.023), Barthel index (r=0.375; p=0.018), hand dynamometry (r=0.395; p=0.014), hand dynamometry index (r=0.340; p=0.021), lean body mass (r=0.414; p=0.009), musculoskeletal mass (r=0.819; p<0.001), proportion of musculoskeletal mass (r=0.796; p<0.001), walking speed (r=0.670; p<0.001), and the results of the sit-to-stand test (r=-0.541; p<0.001). Sarcopenia was diagnosed in 61 women (41.8%). There were also significant differences in age, hand dynamometry results, hand dynamometry index, walking speed and results of the sit-to-stand test between the two groups depending on their hand grip strength.Conclusion: The use of hand dynamometry, physical activity tests, and bioimpedance phase angle can be used in clinical practice to diagnose sarcopenia.

scholarly journals The Effects of Unit Exercises on the Hand Grip Strength of Arm Wrestlers

2017 ◽  
Vol 5 (6) ◽  
pp. 196
Author(s):  
Sezer S Yonca ◽  
Çelikel B Engin ◽  
Yücel A Serdar ◽  
Karadağ Mustafa ◽  
Savucu Yüksel
Keyword(s):  
Grip Strength ◽  
Exercise Program ◽  
Hand Grip Strength ◽  
Weight Lifting ◽  
Test Analysis ◽  
Significance Level ◽  
Left Hand ◽  
Hand Grip ◽  
Before And After ◽  
The Right

The aim of this research is to evaluate the change in the hand grip strength of the male arm wrestlers before and after a unit of exercise. The participants of the research consist of sportsmen (n=16) of Fırat University arm wrestling team in 18-25 age group.Within the scope of the research, all of the tests and measurements (age, length, body weight, sports age, hand grip strength) were carried out on the experimental group before they started training and the same tests were repeated just after the exercises. A unit of exercise program consisted of warm up, cool down, and 5 sets of weight lifting with 12 repetitions and intensity of 70% that were in that day’s plan and program applied by the trainer.While descriptive statistics were adopted in the statistical analysis, to identify the significance level between the hand grip strength before and after the exercise paired sample t-test analysis was used. The significance level was shown as α = 0.05 in the analyses. While the right hand grip strength of the sportsmen (n=16) was statistically significant at 51.1062 ± 1.69709 before and 49.0437 ± 1.71770 (p=0.000) after the exercise, the left hand grip strength was statistically significant at 46.9000 ± 1.16179 before and 45.8063 ± 1.30078 (p=0.000) after the exercise.In conclusion, it was observed that there is a statistically significant negative decline in the hand grip strength of the arm wrestling sportsmen after a unit of exercise and it can be said that it is because of the exhaustion expected after the exercise.

scholarly journals Measurement of Muscle Strength in Haemodialysis Patients by Pinch and Hand Grip Strength and Comparison to Lean Body Mass Measured by Multifrequency Bio-Electrical Impedance

2016 ◽  
Vol 68 (4) ◽  
pp. 268-275 ◽  
Author(s):  
Yukie Omichi ◽  
Methavee Srivareerat ◽  
Kwanpeemai Panorchan ◽  
George H.B. Greenhall ◽  
Sanjana Gupta ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Grip Strength ◽  
Cell Mass ◽  
Hand Grip Strength ◽  
Whole Body ◽  
Pinch Strength ◽  
Segmental Body ◽  
Hand Grip ◽  
Total Body ◽  
Venous Fistula

Background: Muscle weakness is a risk factor for mortality in haemodialysis (HD) patients; we wished to determine whether measuring the composition of the arm with bioimpedance was associated with arm muscle strength. Methods: We measured pinch strength (PS) and hand grip strength (HGS) in 250 adult HD patients with corresponding post-dialysis multifrequency bioelectrical assessments with segmental body analysis. Results: Mean age 64.0 ± 15.6, 66% male and 45.6% diabetic. The maximum HGS in the dominant or non-fistula arm was 18.9 ± 9.2 kg and PS 4.09 ± 1.96 kg respectively, with a correlation of r = 0.80, p < 0.001. HGS was associated with body cell mass (β 0.37, p < 0.001) and PS with appendicular muscle mass (β 0.06, p < 0.001). Both HGS and PS were independently associated with the ratio of extracellular water (ECW) to total body water (TBW); β -139.5, p = 0.024, β -44.8, p < 0.001 in the arm. The presence of an arterio-venous fistula increased the ECW/TBW ratio in the arm from 0.383 ± 0.009 to 0.390 ± 0.012, p < 0.05. Conclusion: Muscle strength measured by HGS and PS was associated with both markers of whole body and segmental body composition within the arm, particularly ECW/TBW. Bioimpedance measurements and assessment of muscle strength should be measured in the non-fistula arm.

Sign in / Sign up

Export Citation Format

Share Document