scholarly journals Franken-CT: Head and Neck MR-Based Pseudo-CT Synthesis Using Diverse Anatomical Overlapping MR-CT Scans

2021 ◽  
Vol 11 (8) ◽  
pp. 3508
Author(s):  
Pedro Miguel Martinez-Girones ◽  
Javier Vera-Olmos ◽  
Mario Gil-Correa ◽  
Ana Ramos ◽  
Lina Garcia-Cañamaque ◽  
...  

Typically, pseudo-Computerized Tomography (CT) synthesis schemes proposed in the literature rely on complete atlases acquired with the same field of view (FOV) as the input volume. However, clinical CTs are usually acquired in a reduced FOV to decrease patient ionization. In this work, we present the Franken-CT approach, showing how the use of a non-parametric atlas composed of diverse anatomical overlapping Magnetic Resonance (MR)-CT scans and deep learning methods based on the U-net architecture enable synthesizing extended head and neck pseudo-CTs. Visual inspection of the results shows the high quality of the pseudo-CT and the robustness of the method, which is able to capture the details of the bone contours despite synthesizing the resulting image from knowledge obtained from images acquired with a completely different FOV. The experimental Zero-Normalized Cross-Correlation (ZNCC) reports 0.9367 ± 0.0138 (mean ± SD) and 95% confidence interval (0.9221, 0.9512); the experimental Mean Absolute Error (MAE) reports 73.9149 ± 9.2101 HU and 95% confidence interval (66.3383, 81.4915); the Structural Similarity Index Measure (SSIM) reports 0.9943 ± 0.0009 and 95% confidence interval (0.9935, 0.9951); and the experimental Dice coefficient for bone tissue reports 0.7051 ± 0.1126 and 95% confidence interval (0.6125, 0.7977). The voxel-by-voxel correlation plot shows an excellent correlation between pseudo-CT and ground-truth CT Hounsfield Units (m = 0.87; adjusted R2 = 0.91; p < 0.001). The Bland–Altman plot shows that the average of the differences is low (−38.6471 ± 199.6100; 95% CI (−429.8827, 352.5884)). This work serves as a proof of concept to demonstrate the great potential of deep learning methods for pseudo-CT synthesis and their great potential using real clinical datasets.

2021 ◽  
Vol 38 (5) ◽  
pp. 1361-1368
Author(s):  
Fatih M. Senalp ◽  
Murat Ceylan

The thermal camera systems can be used in all kinds of applications that require the detection of heat change, but thermal imaging systems are highly costly systems. In recent years, developments in the field of deep learning have increased the success by obtaining quality results compared to traditional methods. In this paper, thermal images of neonates (healthy - unhealthy) obtained from a high-resolution thermal camera were used and these images were evaluated as high resolution (ground truth) images. Later, these thermal images were downscaled at 1/2, 1/4, 1/8 ratios, and three different datasets consisting of low-resolution images in different sizes were obtained. In this way, super-resolution applications have been carried out on the deep network model developed based on generative adversarial networks (GAN) by using three different datasets. The successful performance of the results was evaluated with PSNR (peak signal to noise ratio) and SSIM (structural similarity index measure). In addition, healthy - unhealthy classification application was carried out by means of a classifier network developed based on convolutional neural networks (CNN) to evaluate the super-resolution images obtained using different datasets. The obtained results show the importance of combining medical thermal imaging with super-resolution methods.


2021 ◽  
Vol 20 ◽  
pp. 153303382110624
Author(s):  
Xudong Xue ◽  
Yi Ding ◽  
Jun Shi ◽  
Xiaoyu Hao ◽  
Xiangbin Li ◽  
...  

Objective: To generate synthetic CT (sCT) images with high quality from CBCT and planning CT (pCT) for dose calculation by using deep learning methods. Methods: 169 NPC patients with a total of 20926 slices of CBCT and pCT images were included. In this study the CycleGAN, Pix2pix and U-Net models were used to generate the sCT images. The Mean Absolute Error (MAE), Root Mean Squared Error (RMSE), Peak Signal to Noise Ratio (PSNR), and Structural Similarity Index (SSIM) were used to quantify the accuracy of the proposed models in a testing cohort of 34 patients. Radiation dose were calculated on pCT and sCT following the same protocol. Dose distributions were evaluated for 4 patients by comparing the dose-volume-histogram (DVH) and 2D gamma index analysis. Results: The average MAE and RMSE values between sCT by three models and pCT reduced by 15.4 HU and 26.8 HU at least, while the mean PSNR and SSIM metrics between sCT by different models and pCT added by 10.6 and 0.05 at most, respectively. There were only slight differences for DVH of selected contours between different plans. The passing rates of 2D gamma index analysis under 3 mm/3% 3 mm/2%, 2 mm/3%and 2 mm/2% criteria were all higher than 95%. Conclusions: All the sCT had achieved better evaluation metrics than those of original CBCT, while the performance of CycleGAN model was proved to be best among three methods. The dosimetric agreement confirmed the HU accuracy and consistent anatomical structures of sCT by deep learning methods.


Stroke ◽  
2021 ◽  
Author(s):  
Girish Bathla ◽  
Yanan Liu ◽  
Honghai Zhang ◽  
Milan Sonka ◽  
Colin Derdeyn

Background and Purpose: We explored the feasibility of automated, arterial input function independent, vendor neutral prediction of core infarct, and penumbral tissue using complete and partial computed tomographic perfusion data sets through neural networks. Methods: Using retrospective computed tomographic perfusion data from 57 patients, split as training/validation (60%/40%), we developed and validated separate 2-dimensional U-net models for cerebral blood flow (CBF) and time to maximum (Tmax) maps calculation to predict core infarct and tissue at risk, respectively. Once trained, the full sets of 28 input images were sequentially reduced to equitemporal 14, 10, and 7 time points. The averaged structural similarity index measure between the model-derived images and ground truth perfusion maps was compared. Volumes for core infarct and Tmax were compared using the Pearson correlation coefficient. Results: Both CBF and Tmax maps derived using 28 and 14 time points had similar structural similarity index measure (0.80–0.81; P >0.05) when compared with ground truth images. The Pearson correlation for the CBF and Tmax volumes derived from the model using 28-tp with ground truth volumes derived from the RAPID software was 0.69 for CBF and 0.74 for Tmax. The predicted maps were fully concordant in terms of laterality to the commercial perfusion maps. The mean Dice scores were 0.54 for the core infarct and 0.63 for the hypoperfusion maps. Conclusion: Artificial intelligence model-derived volumes show good correlation with RAPID-derived volumes for CBF and Tmax. Within the constraints of a small sample size, the perfusion map quality is similar when using 14-tp instead of 28-tp. Our findings provide proof of concept that vendor neutral artificial intelligence models for computed tomographic perfusion processing using complete or partial image data sets appear feasible. The model accuracy could be further optimized using larger data sets.


2020 ◽  
Vol 25 (2) ◽  
pp. 86-97
Author(s):  
Sandy Suryo Prayogo ◽  
Tubagus Maulana Kusuma

DVB merupakan standar transmisi televisi digital yang paling banyak digunakan saat ini. Unsur terpenting dari suatu proses transmisi adalah kualitas gambar dari video yang diterima setelah melalui proses transimisi tersebut. Banyak faktor yang dapat mempengaruhi kualitas dari suatu gambar, salah satunya adalah struktur frame dari video. Pada tulisan ini dilakukan pengujian sensitifitas video MPEG-4 berdasarkan struktur frame pada transmisi DVB-T. Pengujian dilakukan menggunakan simulasi matlab dan simulink. Digunakan juga ffmpeg untuk menyediakan format dan pengaturan video akan disimulasikan. Variabel yang diubah dari video adalah bitrate dan juga group-of-pictures (GOP), sedangkan variabel yang diubah dari transmisi DVB-T adalah signal-to-noise-ratio (SNR) pada kanal AWGN di antara pengirim (Tx) dan penerima (Rx). Hasil yang diperoleh dari percobaan berupa kualitas rata-rata gambar pada video yang diukur menggunakan metode pengukuran structural-similarity-index (SSIM). Dilakukan juga pengukuran terhadap jumlah bit-error-rate BER pada bitstream DVB-T. Percobaan yang dilakukan dapat menunjukkan seberapa besar sensitifitas bitrate dan GOP dari video pada transmisi DVB-T dengan kesimpulan semakin besar bitrate maka akan semakin buruk nilai kualitas gambarnya, dan semakin kecil nilai GOP maka akan semakin baik nilai kualitasnya. Penilitian diharapkan dapat dikembangkan menggunakan deep learning untuk memperoleh frame struktur yang tepat di kondisi-kondisi tertentu dalam proses transmisi televisi digital.


Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3719
Author(s):  
Aoxin Ni ◽  
Arian Azarang ◽  
Nasser Kehtarnavaz

The interest in contactless or remote heart rate measurement has been steadily growing in healthcare and sports applications. Contactless methods involve the utilization of a video camera and image processing algorithms. Recently, deep learning methods have been used to improve the performance of conventional contactless methods for heart rate measurement. After providing a review of the related literature, a comparison of the deep learning methods whose codes are publicly available is conducted in this paper. The public domain UBFC dataset is used to compare the performance of these deep learning methods for heart rate measurement. The results obtained show that the deep learning method PhysNet generates the best heart rate measurement outcome among these methods, with a mean absolute error value of 2.57 beats per minute and a mean square error value of 7.56 beats per minute.


Author(s):  
Cuizhen Wang ◽  
Zhenxue Chen ◽  
Yan Wang ◽  
Zhifeng Wang

Three-dimensional reconstruction of teeth plays an important role in the operation of living dental implants. However, the tissue around teeth and the noise generated in the process of image acquisition bring a serious impact on the reconstruction results, which must be reduced or eliminated. Combined with the advantages of wavelet transform and bilateral filtering, this paper proposes an image denoising method based on the above methods. The method proposed in this paper not only removes the noise but also preserves the image edge details. The noise in high frequency subbands is denoised using a locally adaptive thresholding and the noise in low frequency subbands is filtered by the bilateral filtering. Peak signal-to-noise ratio (PSNR), structural similarity index measure (SSIM) and 3D reconstruction using the iso-surface extraction method are used to evaluate the denoising effect. The experimental results show that the proposed method is better than the wavelet denoising and bilateral filtering, and the reconstruction results meet the requirements of clinical diagnosis.


2021 ◽  
Vol 7 (2) ◽  
pp. 75
Author(s):  
Halim Bayuaji Sumarna ◽  
Ema Utami ◽  
Anggit Dwi Hartanto

Image enhancement merupakan prosedur yang digunakan untuk memproses gambar sehingga dapat memperbaiki atau meningkatkan kualitas gambar agar selanjutnya dapat dianalis untuk tujuan tertentu. Ada banyak algoritma image enhancement yang dapat diterapkan pada suatu gambar, salah satunya dapat menggunakan algoritma structural similarity index measure (SSIM), algoritma ini berfungsi sebagai alat ukur dalam menilai kualitas gambar, bekerja dengan membandingkan fitur structural dari gambar, dan kualitas gambar dijelaskan oleh kesamaan structural. Selain untuk menilai kualitas suatu gambar, SSIM dapat menjadi metode dalam menganalisis perbedaan gambar, sehingga diketahui anomali dari perbandingan dua gambar berdasarkan data structural dari sebuah gambar. Tinjauan literature sistematis ini digunakan untuk menganalisis dan fokus pada algoritma SSIM dalam mengetahui anomaly 2 gambar yang terlihat mirip secara human visual system. Hasil sistematis review menunjukkan bahwa penggunaan algoritma SSIM dalam menilai kualitas gambar berkorelasi kuat dengan HVS (Human Vision System) dan dalam deteksi anomaly gambar menghasilkan akurasi yang berbeda, karena terpengaruh intensitas cahaya dan posisi kamera dalam mengambil gambar sebagai dataset.Kata Kunci— SSIM, anomaly, gambar, deteksiImage enhancement is a procedure used to process images so that they can correct or improve image quality so that they can then be analyzed for specific purposes. Many image enhancement algorithms can be applied to an image. one of the usable methods is the structural similarity index measure (SSIM) algorithm, this algorithm serves as a measuring tool in assessing image quality. It works by comparing the structural features of images, and the image quality is explained by structural similarity. In addition to assessing the quality of an image, SSIM can be a method of analyzing image differences. So, the anomalies are known from the comparison of two images based on the structural data from an image. This systematic literature review is used to analyze and focus on the SSIM algorithm in knowing anomaly 2 images that look similar to the human visual system. Systematic review results show that the use of the SSIM algorithm in assessing image quality is strongly correlated with HVS (Human Vision System). In anomaly detection of images produces different accuracy because it is affected by light intensity and camera position in taking pictures as a dataset.Keywords— SSIM, anomaly, gambar, deteksi


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