scholarly journals Intra-System Reliability Assessment of 2-Dimensional Shear Wave Elastography

2021 ◽  
Vol 11 (7) ◽  
pp. 2992
Author(s):  
Christopher Edwards ◽  
Erika Cavanagh ◽  
Sailesh Kumar ◽  
Vicki Clifton ◽  
Davide Fontanarosa
Keyword(s):  
Shear Wave ◽  
System Reliability ◽  
Soft Tissues ◽  
Reliability Assessment ◽  
Sampling Technique ◽  
Shear Wave Elastography ◽  
Medical Ultrasound ◽  
Measurement Variability ◽  
Pathological Conditions ◽  
System Variability

The availability of 2-Dimensional Shear Wave Elastography (2D-SWE) technology on modern medical ultrasound systems is becoming increasingly common. The technology is now being used to investigate a range of soft tissues and related pathological conditions. This work investigated the reliability of a single commercial 2D-SWE system using a tissue-mimicking elastography phantom to understand the major causes of intra-system variability. Sources of shear wave velocity (SWV) measurement variability relates to imaging depth, target stiffness, sampling technique and the operator. Higher SWV measurement variability was evident with increasing depth and stiffness of the phantom targets. The influence of the operator was minimal, and variations in sampling technique had little impact on the SWV.

scholarly journals Evaluation of Inter-System Variability in Liver Stiffness Measurements

2018 ◽  
Vol 40 (01) ◽  
pp. 64-75 ◽  
Author(s):  
Giovanna Ferraioli ◽  
Annalisa De Silvestri ◽  
Raffaella Lissandrin ◽  
Laura Maiocchi ◽  
Carmine Tinelli ◽  
...  
Keyword(s):  
Shear Wave ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Mean Difference ◽  
Observer Agreement ◽  
Concordance Correlation ◽  
Limits Of Agreement ◽  
Inter Observer Variability ◽  
System Variability ◽  
The Mean

Abstract Aim The primary aim of this study was to determine the inter-system variability of liver stiffness measurements (LSMs) in patients with varying degrees of liver stiffness. The secondary aim was to determine the inter-observer variability of measurements. Materials and Methods 21 individuals affected by chronic hepatitis C and 5 healthy individuals were prospectively enrolled. The assessment of LSMs was performed using six ultrasound (US) systems, four of which with point shear wave elastography (p-SWE) and two with 2 D shear wave elastography (2D-SWE) systems. The Fibroscan (Echosens, France) was used as the reference standard. Four observers performed the measurements in pairs (A-B, C-D). The agreement between different observers or methods was calculated using Lin’s concordance correlation coefficient. The Bland-Altman limits of agreement (LOA) were calculated as well. Results There was agreement above 0.80 for all pairs of systems. The mean difference between the values of the systems with 2D-SWE technique was 1.54 kPa, whereas the maximum mean difference between the values of three out of four systems with the pSWE technique was 0.79 kPa. The intra-patient concordance for all systems was 0.89 (95 % CI: 0.83 – 0.94). Inter-observer agreement was 0.96 (95 % CI: 0.94 – 0.98) for the pair of observers A-B and 0.93 (95 % CI: 0.89 – 0.96) for the pair of observers C-D. Conclusion The results of this study show that the agreement between LSMs performed with different US systems is good to excellent and the overall inter-observer agreement in “ideal conditions” is above 0.90 in expert hands.

scholarly journals A Diagnostic Imaging Method – Shear Wave Elastography

2018 ◽  
Vol 1 (1) ◽  
pp. 14-22
Author(s):  
Marketa Zemanova
Keyword(s):  
Diagnostic Imaging ◽  
Shear Wave ◽  
Elastic Properties ◽  
Soft Tissues ◽  
Shear Wave Elastography ◽  
Biological Tissues ◽  
Utilization Rate ◽  
Quantitative Aspect ◽  
Imaging Method ◽  
Endocrine Orbitopathy

Shear Wave Elastography (SWE) is a non-invasive diagnostic imaging technique, that maps the elastic properties of tissues. Nowadays this modality develops increasingly in medicine across its disciplines and opens a new era of high-quality ultrasound examination because it increases the specificity and thus improves diagnostic assurance. This method is similar to manual palpation, shows elastic properties of biological tissues and provides a kind of reconstruction of the internal structure of soft tissues based on measurement of the response of tissue compression. Results: This method is already used routinely in the detection and diagnosis of breast cancer and thyroid cancer, prostate cancer, in hepatology, cardiology, view of the carotid arteries and lymphatic nodules. Standards of elasticity values for human tissues such as the mammary gland, liver, prostate or thyroid gland are progressively being created across the medical fields. Finally, the article examines its unquestioned benefit in ophthalmology. In ophthalmology, it already appears as an up-and-coming method in diagnostics and in evaluating the changes in oculomotor muscles and orbital tissues in patients with endocrine orbitopathy. Conclusion: Shear wave elastography offers three main innovations: the quantitative aspect, dimensional resolution, and real-time imaging ability. Determination of the utilization rate of this method and its inclusion into the diagnostics of endocrine orbitopathy is still a question and the subject of presently conducted clinical studies.

Two-dimensional shear wave elastography with propagation-based reliability assessment for grading hepatic fibrosis and portal hypertension

2016 ◽  
Vol 23 (9) ◽  
pp. 595-602 ◽  
Author(s):  
Hitoshi Maruyama ◽  
Kazufumi Kobayashi ◽  
Soichiro Kiyono ◽  
Tadashi Sekimoto ◽  
Tatsuo Kanda ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Shear Wave ◽  
Hepatic Fibrosis ◽  
Reliability Assessment ◽  
Shear Wave Elastography ◽  
Two Dimensional

scholarly journals Limitations of Muscle Ultrasound Shear Wave Elastography for Clinical Routine—Positioning and Muscle Selection

Sensors ◽  
2021 ◽  
Vol 21 (24) ◽  
pp. 8490
Author(s):  
Alyssa Romano ◽  
Deborah Staber ◽  
Alexander Grimm ◽  
Cornelius Kronlage ◽  
Justus Marquetand
Keyword(s):  
Shear Wave ◽  
Biceps Brachii ◽  
Imaging Modality ◽  
Shear Wave Elastography ◽  
Mechanical Anisotropy ◽  
Tissue Elasticity ◽  
Measurement Variability ◽  
Individual Patient Level ◽  
Measurement Protocol ◽  
Paravertebral Muscles

Shear wave elastography (SWE) is a clinical ultrasound imaging modality that enables non-invasive estimation of tissue elasticity. However, various methodological factors—such as vendor-specific implementations of SWE, mechanical anisotropy of tissue, varying anatomical position of muscle and changes in elasticity due to passive muscle stretch—can confound muscle SWE measurements and increase their variability. A measurement protocol with a low variability of reference measurements in healthy subjects is desirable to facilitate diagnostic conclusions on an individual-patient level. Here, we present data from 52 healthy volunteers in the areas of: (1) Characterizing different limb and truncal muscles in terms of inter-subject variability of SWE measurements. Superficial muscles with little pennation, such as biceps brachii, exhibit the lowest variability whereas paravertebral muscles show the highest. (2) Comparing two protocols with different limb positioning in a trade-off between examination convenience and SWE measurement variability. Repositioning to achieve low passive extension of each muscle results in the lowest SWE variability. (3) Providing SWE shear wave velocity (SWV) reference values for a specific ultrasound machine/transducer setup (Canon Aplio i800, 18 MHz probe) for a number of muscles and two positioning protocols. We argue that methodological issues limit the current clinical applicability of muscle SWE.

scholarly journals Viscoelasticity Imaging of Biological Tissues and Single Cells Using Shear Wave Propagation

2021 ◽  
Vol 9 ◽  
Author(s):  
Hongliang Li ◽  
Guillaume Flé ◽  
Manish Bhatt ◽  
Zhen Qu ◽  
Sajad Ghazavi ◽  
...  
Keyword(s):  
Wave Propagation ◽  
Shear Wave ◽  
Soft Tissues ◽  
Acoustic Radiation ◽  
Single Cells ◽  
Shear Waves ◽  
Mechanical Vibration ◽  
Shear Wave Elastography ◽  
Biomechanical Properties ◽  
Biological Tissues

Changes in biomechanical properties of biological soft tissues are often associated with physiological dysfunctions. Since biological soft tissues are hydrated, viscoelasticity is likely suitable to represent its solid-like behavior using elasticity and fluid-like behavior using viscosity. Shear wave elastography is a non-invasive imaging technology invented for clinical applications that has shown promise to characterize various tissue viscoelasticity. It is based on measuring and analyzing velocities and attenuations of propagated shear waves. In this review, principles and technical developments of shear wave elastography for viscoelasticity characterization from organ to cellular levels are presented, and different imaging modalities used to track shear wave propagation are described. At a macroscopic scale, techniques for inducing shear waves using an external mechanical vibration, an acoustic radiation pressure or a Lorentz force are reviewed along with imaging approaches proposed to track shear wave propagation, namely ultrasound, magnetic resonance, optical, and photoacoustic means. Then, approaches for theoretical modeling and tracking of shear waves are detailed. Following it, some examples of applications to characterize the viscoelasticity of various organs are given. At a microscopic scale, a novel cellular shear wave elastography method using an external vibration and optical microscopy is illustrated. Finally, current limitations and future directions in shear wave elastography are presented.

scholarly journals Shear wave elastography parameters of normal soft tissues of the neck

2017 ◽  
Vol 161 (3) ◽  
pp. 320-325 ◽  
Author(s):  
Jan Herman ◽  
Zuzana Sedlackova ◽  
Jaromir Vachutka ◽  
Tomas Furst ◽  
Richard Salzman ◽  
...  
Keyword(s):  
Shear Wave ◽  
Soft Tissues ◽  
Shear Wave Elastography

Characterization of tissue mimicking phantoms and soft tissues using ultrasound shear wave elastography and power-law models

2020 ◽  
Vol 148 (4) ◽  
pp. 2598-2598
Author(s):  
Matthew W. Urban ◽  
Piotr Kijanka ◽  
Benjamin Wood ◽  
Robert J. McGough
Keyword(s):  
Shear Wave ◽  
Power Law ◽  
Soft Tissues ◽  
Shear Wave Elastography

scholarly journals Reverberant Shear Wave Elastography: A Multi-Modal and Multi-Scale Approach to Measure the Viscoelasticity Properties of Soft Tissues

2021 ◽  
Vol 8 ◽  
Author(s):  
Juvenal Ormachea ◽  
Fernando Zvietcovich
Keyword(s):  
Wave Propagation ◽  
Shear Wave ◽  
Acoustic Waves ◽  
Guided Waves ◽  
Soft Tissues ◽  
Ex Vivo ◽  
Surface Acoustic Waves ◽  
Shear Wave Elastography ◽  
Biomechanical Properties

There are a variety of approaches used to create elastography images. Techniques based on shear wave propagation have received significant attention. However, there remain some limitations and problems due to shear wave reflections, limited penetration in highly viscous media, requirements for prior knowledge of wave propagation direction, and complicated propagation in layers where surface acoustic waves and guided waves are dominant. To overcome these issues, reverberant shear wave elastography (RSWE) was proposed as an alternative method which applies the concept of a narrow-band diffuse field of shear waves within the tissue. Since 2017, the RSWE approach has been implemented in ultrasound (US) and optical coherence tomography (OCT). Specifically, this approach has been implemented in these imaging modalities because they are similar in image formation principles and both share several approaches to estimate the biomechanical properties in tissues. Moreover, they cover different spatial-scale and penetration depth characteristics. RSWE has shown promising results in the elastic and viscoelastic characterization of multiple tissues including liver, cornea, and breast. This review summarizes the 4-year progress of the RSWE method in US and OCT. Theoretical derivations, numerical simulations, and applications in ex vivo and in vivo tissues are shown. Finally, we emphasize the current challenges of RSWE in terms of excitation methods and estimation of biomechanical parameters for tissue-specific cases and discuss future pathways for the in vivo and in situ clinical implementations.

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