scholarly journals The New York City COVID-19 Spread in the 2020 Spring: A Study on the Potential Role of Particulate Using Time Series Analysis and Machine Learning

2021 ◽  
Vol 11 (3) ◽  
pp. 1177
Author(s):  
Silvia Mirri ◽  
Marco Roccetti ◽  
Giovanni Delnevo

This study investigates the potential association between the daily distribution of the PM2,5 air pollutant and the initial spreading of COVID-19 in New York City. We study the period from 4 March to 22 March 2020, and apply our analysis to all five counties, including the city, plus seven neighboring counties, including both urban and peripheral districts. Using the Granger causality methodology, and considering the maximum lag period (14 days) between infection and the correspondent diagnosis, we found that the time series of the new daily infections registered in those 12 counties appear to correlate to the time series of the concentrations of the PM2.5 particulate circulating in the air, with 33 over 36 statistical tests with a p-value less than 0.005, thus confirming such a hypothesis. Moreover, looking for further confirmation of this association, we train four different machine learning algorithms on a portion of those time series. These are able to predict that the number of the new daily infections would have surpassed a given infections threshold for the remaining portion of the series, with an average accuracy ranging from 84% to 95%, depending on the algorithm and/or on the specific county under observation. This is similar to other results obtained from several polluted urban areas, e.g., Wuhan, Xiaogan, and Huanggang in China, and Northern Italy. Our study provides further evidence that ambient air pollutants can be associated with a daily COVID-19 infection incidence.

2012 ◽  
Vol 03 (09) ◽  
pp. 1102-1116 ◽  
Author(s):  
Carlos E. Restrepo ◽  
Jeffrey S. Simonoff ◽  
George D. Thurston ◽  
Rae Zimmerman

Author(s):  
Akhil Vaid ◽  
Sulaiman Somani ◽  
Adam J Russak ◽  
Jessica K De Freitas ◽  
Fayzan F Chaudhry ◽  
...  

AbstractCoronavirus 2019 (COVID-19), caused by the SARS-CoV-2 virus, has become the deadliest pandemic in modern history, reaching nearly every country worldwide and overwhelming healthcare institutions. As of April 20, there have been more than 2.4 million confirmed cases with over 160,000 deaths. Extreme case surges coupled with challenges in forecasting the clinical course of affected patients have necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods for achieving this are lacking. In this paper, we use electronic health records from over 3,055 New York City confirmed COVID-19 positive patients across five hospitals in the Mount Sinai Health System and present a decision tree-based machine learning model for predicting in-hospital mortality and critical events. This model is first trained on patients from a single hospital and then externally validated on patients from four other hospitals. We achieve strong performance, notably predicting mortality at 1 week with an AUC-ROC of 0.84. Finally, we establish model interpretability by calculating SHAP scores to identify decisive features, including age, inflammatory markers (procalcitonin and LDH), and coagulation parameters (PT, PTT, D-Dimer). To our knowledge, this is one of the first models with external validation to both predict outcomes in COVID-19 patients with strong validation performance and identify key contributors in outcome prediction that may assist clinicians in making effective patient management decisions.One-Sentence SummaryWe identify clinical features that robustly predict mortality and critical events in a large cohort of COVID-19 positive patients in New York City.


Epidemiology ◽  
2006 ◽  
Vol 17 (Suppl) ◽  
pp. S266 ◽  
Author(s):  
C Restrepo ◽  
J Simonoff ◽  
G Thurston ◽  
R Zimmerman

2014 ◽  
Vol 24 (5) ◽  
pp. 497-500 ◽  
Author(s):  
Michael Johns ◽  
Shannon M Farley ◽  
Deepa T Rajulu ◽  
Susan M Kansagra ◽  
Harlan R Juster

2006 ◽  
Vol 40 (10) ◽  
pp. 788-795 ◽  
Author(s):  
Prasanna Venkatachari ◽  
Liming Zhou ◽  
Philip K. Hopke ◽  
James J. Schwab ◽  
Kenneth L. Demerjian ◽  
...  

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