scholarly journals Measurement and Analysis of Vibration Levels for Truck Transport Environment in Korea

2020 ◽  
Vol 10 (19) ◽  
pp. 6754 ◽  
Author(s):  
Jongmin Park ◽  
Sangil Choi ◽  
Hyun Mo Jung
Keyword(s):  
Travel Speed ◽  
International Standards ◽  
Statistical Characteristics ◽  
Leaf Spring ◽  
Low Level ◽  
Simulation Protocol ◽  
Truck Transport ◽  
Heavy Tailed ◽  
The Right ◽  
High Level

The first step in the appropriate packaging design of food, agricultural and industrial products is to conduct an accurate simulation of the vehicle transport environment, in which a power spectral density (PSD) profile is applied. Although several researchers have mentioned the limitations of PSD-based simulation, it is still widely used because accelerated test conditions can be easily generated from the PSD acquired from a particular transport section. In this study, three representative trucks and transport test routes of domestic freight transport were selected to develop a simulation protocol for a truck transport environment in Korea. These studies are needed to compare domestic transport vibration levels with those presented by the International Standards (ASTM: West Conshohocken, USA, ISTA: Chicago, USA) and to simulate damage to packaged products by domestic transport environments. The composite PSD profile for the truck transport environment was established by dividing it into high-and low-level composite PSD profiles representing the top 30% and lower 70%, respectively, of the measured vibration events based on the root-mean-square acceleration (rms G) of the measured vibration events. Also, the effects of these variables on the truck vibration level were analyzed by extracting data corresponding to the truck’s pre-planned travel speed and road conditions in the vibration records measured on the test route. Moreover, kurtosis, skewness, and normal quantile-quantity (Q-Q) analyses were conducted to understand the statistical characteristics of Korea’s truck transport environment. Statistical analysis showed that the measured vibration events had a heavy-tailed distribution and skewed to the right, causing dissymmetry. The overall rms G of the developed high-level and low-level composite PSD profiles in the range from 1 to 250 Hz were 0.47 and 0.32 for leaf-spring trucks and 0.30 and 0.14 for air-ride trucks, respectively.

scholarly journals Comparison of Methods for Extraction of Tobacco Alkaloids

2001 ◽  
Vol 84 (2) ◽  
pp. 309-316 ◽  
Author(s):  
Nadiá M Jones ◽  
M Gabriela Bernardo-Gil ◽  
M Graço Lourenco
Keyword(s):  
Ultrasonic Method ◽  
Extraction Methods ◽  
International Standards ◽  
Low Level ◽  
Aoac Method ◽  
Tobacco Alkaloids ◽  
Microwave Techniques ◽  
High Level ◽  
International Standards Organization ◽  
Solvent Volume

Abstract Ultrasound and microwave techniques were used to extract tobacco alkaloids, and response surface methodology was used to optimize extraction conditions. Ultrasonic technique factors were temperature, 30–85°C; time, 3–45 min; solvent volume, 8–80 mL. Microwave extraction factors were pressure, 15–75 psi; time, 3–40 min; power, 30–90% of the maximum magnetron power of 650 W. Soxhlet and solvent AOAC-modified extraction methods were also applied after some improvements. Nicotine, nornicotine, anabasine, and anatabine were quantified by gas chromatography. A steam distillation International Standards Organization method for total alkaloid evaluation was used as reference. The results obtained by the different methods were compared using a least squares deviation test. The ultrasonic and the proposed modified-AOAC extraction method were the more convenient with regard to practicability and precision. The relative deviations (n = 5) were as follows: For the ultrasonic method in low-level alkaloid tobaccos, 0.7% nicotine and 1.4–14% minor alkaloids; in high-level alkaloid tobaccos, 2.4% nicotine and 4.5–5.1% minor alkaloids. For the modified AOAC method in low-level alkaloid tobaccos, 0.9% nicotine and 2.4–11.6% minor alkaloids; and in high-level alkaloid tobaccos, 1.7% nicotine and 2.0–2.4% minor alkaloids.

scholarly journals Abstracting Causal Models

2019 ◽  
Vol 33 ◽  
pp. 2678-2685 ◽  
Author(s):  
Sander Beckers ◽  
Joseph Y. Halpern
Keyword(s):  
Causal Models ◽  
Low Level ◽  
The Right ◽  
High Level ◽  
Macro Variables

We consider a sequence of successively more restrictive definitions of abstraction for causal models, starting with a notion introduced by Rubenstein et al. (2017) called exact transformation that applies to probabilistic causal models, moving to a notion of uniform transformation that applies to deterministic causal models and does not allow differences to be hidden by the “right” choice of distribution, and then to abstraction, where the interventions of interest are determined by the map from low-level states to high-level states, and strong abstraction, which takes more seriously all potential interventions in a model, not just the allowed interventions. We show that procedures for combining micro-variables into macro-variables are instances of our notion of strong abstraction, as are all the examples considered by Rubenstein et al.

Design and Validation of a Torque Controllable Hip Exoskeleton for Walking Assistance

2018 ◽  
Author(s):  
Inseung Kang ◽  
Hsiang Hsu ◽  
Aaron J. Young
Keyword(s):  
Torque Control ◽  
Mechanical Power ◽  
Ball Screw ◽  
Leaf Spring ◽  
Accurate Information ◽  
Low Level ◽  
High Level ◽  
Hip Flexion ◽  
Human Augmentation ◽  
Power Assistance

Recent technological advancements have expanded the field of human augmentation. Specifically, lower limb exoskeletons have benefited many by providing assistance to increase mobility. The proposed study aims to develop a novel bilateral hip exoskeleton that provides mechanical power assistance in both hip flexion and extension during walking. Each actuation unit employs series elastic actuator for a high fidelity closed loop torque control utilizing a ball screw transmission incorporated with a fiberglass leaf spring. The control architecture was divided into three tiers and each tier implemented different control algorithms. The device was experimentally validated with both benchtop and human testing. Benchtop testing was done to tune required control parameters in the low-level controller and to validate the torque response. We tested five able-bodied subjects walking with our device. We analyzed their kinematic and kinetic data with different levels of mechanical power assistance during walking. Our benchtop testing results showed that the low-level PID gains were tuned to achieve desired bandwidth and torque tracking. Human testing results demonstrated that the high-level controller provided an accurate information for assistance onset timing that the hip exoskeleton was able to assist the user effectively.

scholarly journals PENERAPAN DATA MINING PADA JUMLAH PELANGGAN PERUSAHAAN AIR BERSIH MENURUT PROVINSI MENGGUNAKAN METODE K-MEANS CLUSTERING

2019 ◽  
Vol 2 (2) ◽  
pp. 119-125
Author(s):  
Lestari Sinaga ◽  
Abdullah Ahmad ◽  
Muhammad Safii
Keyword(s):  
Calculated Data ◽  
Clean Water ◽  
Low Level ◽  
Central Java ◽  
Medium Level ◽  
Centroid Point ◽  
Water Companies ◽  
The Right ◽  
High Level ◽  
Number Of Customers

Water is one of the primary needs for humans so that everyone has the right to get clean water for their daily needs. Along with increasing population, the need for water will increase. So with that the PDAM must sell clean / decent water to its customers, clean water becomes the focus of attention and has the greatest power compared to other problems. Because water is a basic necessity, most of the companies impose rates that can be reached by the community and prices are adjusted to the growth in demand. The purpose of this research is to get a grouping of the number of customers of clean water companies in all provinces using the K-Means Algorithm, K-Means is a method for grouping data into a cluster by calculating the closest distance from a data to a centroid point. Clusters used are high level clusters (C1), medium level clusters (C2), and for low level clusters (C3). Centroid data obtained is for high-level clusters (C1) which are as many as 7710154, for medium-level clusters as much as 929586, and for low-level clusters as much as 112462. Based on the calculated data obtained high-level results, namely the province of Indonesia, for the medium level namely province North Sumatra, DKI Jakarta, West Java, Central Java and East Java, and other provinces are low levels. So that this result can be a support for the company in order to increase water needs.

Some Comments on the Highest Attainable Standard of Health

2020 ◽  
Vol 26 (2) ◽  
pp. 134-140
Author(s):  
Gabriela Belova ◽  
Stanislav Pavlov
Keyword(s):  
Health Resources ◽  
Right To Health ◽  
International Standards ◽  
Special Rapporteur ◽  
Health It ◽  
Significant Development ◽  
Cultural Rights ◽  
Optional Protocol ◽  
The Social ◽  
The Right

AbstractThe last decades present a significant development of the economic, social and cultural rights and specifically, the right to health. Until 2000, the right to health has not been interpreted officially. By providing international standards, General Comment No.14 on the right to the Highest Attainable Standard of Health has led to wider agreement that the right to health includes the social determinants of health such as access to various conditions, services, goods or facilities that are crucial for its implementation. The Reports of the Special Rapporteur on the right to health within the UN human rights system have contributed to the process of gaining the greater clarity about the right to health. It is obvious that achieving the highest attainable level of health depends on the principle of progressive implementation and the availability of the necessary health resources. The possibility individual complaints to be considered by the Committee on Economic Social and Cultural Rights was introduced with the Optional Protocol to the International Covenant on Economic, Social and Cultural Rights, entered into force in 2013.

Teknik Data Mining Dalam Clustering Produksi Susu Segar Di Indonesia Dengan Algoritma K-Means

2019 ◽  
Vol 1 (1) ◽  
pp. 31-39
Author(s):  
Ilham Safitra Damanik ◽  
Sundari Retno Andani ◽  
Dedi Sehendro
Keyword(s):  
Data Mining ◽  
Milk Production ◽  
Clustering Algorithm ◽  
Clustering Method ◽  
Data Mining Techniques ◽  
Low Level ◽  
Fresh Milk ◽  
Nutritional Needs ◽  
High Level ◽  
Level Cluster

Milk is an important intake to meet nutritional needs. Both consumed by children, and adults. Indonesia has many producers of fresh milk, but it is not sufficient for national milk needs. Data mining is a science in the field of computers that is widely used in research. one of the data mining techniques is Clustering. Clustering is a method by grouping data. The Clustering method will be more optimal if you use a lot of data. Data to be used are provincial data in Indonesia from 2000 to 2017 obtained from the Central Statistics Agency. The results of this study are in Clusters based on 2 milk-producing groups, namely high-dairy producers and low-milk producing regions. From 27 data on fresh milk production in Indonesia, two high-level provinces can be obtained, namely: West Java and East Java. And 25 others were added in 7 provinces which did not follow the calculation of the K-Means Clustering Algorithm, including in the low level cluster.

Challenges of Media Education Standards in Georgia

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Marine Vekua
Keyword(s):  
Working Conditions ◽  
Teaching Methods ◽  
International Standards ◽  
The Other ◽  
Historical Background ◽  
Journalism Education ◽  
Education Standards ◽  
Modern Media ◽  
The One ◽  
The Right

The main goal of this research is to determine whether the journalism education of the leading media schools inGeorgia is adequate to modern media market’s demands and challenges. The right answer to this main questionwas found after analyzing Georgian media market’s demands, on the one hand, and, on the other hand, differentaspects of journalism education in Georgia: the historical background, development trends, evaluation ofeducational programs and curricula designs, reflection of international standards in teaching methods, studyingand working conditions.

Determinants of Abuse of the Bodies of the Dead

2019 ◽  
pp. 71-77
Author(s):  
Margarita Khomyakova
Keyword(s):  
Low Income ◽  
Criminal Code ◽  
Value Judgments ◽  
Legal Norms ◽  
Low Level ◽  
Medical Institutions ◽  
Specific Object ◽  
The Subject ◽  
The Dead ◽  
High Level

The author analyzes definitions of the concepts of determinants of crime given by various scientists and offers her definition. In this study, determinants of crime are understood as a set of its causes, the circumstances that contribute committing them, as well as the dynamics of crime. It is noted that the Russian legislator in Article 244 of the Criminal Code defines the object of this criminal assault as public morality. Despite the use of evaluative concepts both in the disposition of this norm and in determining the specific object of a given crime, the position of criminologists is unequivocal: crimes of this kind are immoral and are in irreconcilable conflict with generally accepted moral and legal norms. In the paper, some views are considered with regard to making value judgments which could hardly apply to legal norms. According to the author, the reasons for abuse of the bodies of the dead include economic problems of the subject of a crime, a low level of culture and legal awareness; this list is not exhaustive. The main circumstances that contribute committing abuse of the bodies of the dead and their burial places are the following: low income and unemployment, low level of criminological prevention, poor maintenance and protection of medical institutions and cemeteries due to underperformance of state and municipal bodies. The list of circumstances is also open-ended. Due to some factors, including a high level of latency, it is not possible to reflect the dynamics of such crimes objectively. At the same time, identification of the determinants of abuse of the bodies of the dead will reduce the number of such crimes.

IMMUNOTHERAPY FOR NSCLC: THE RIGHT TREATMENT FOR THE RIGHT PERSON

2019 ◽  
Vol 65 (1) ◽  
pp. 27-41
Author(s):  
Yelena Artamonova
Keyword(s):  
Life Expectancy ◽  
Tumor Cells ◽  
Advanced Nsclc ◽  
Objective Response ◽  
Combination Group ◽  
Line Treatment ◽  
Phase 3 ◽  
Median Response ◽  
The Right ◽  
High Level

Lung cancer is the leading cause of mortality from malignant tumors all over the world. Since most patients at the time of diagnosis already have stage III-IV of the disease, the search for new effective treatment strategies for advanced NSCLC is the most important problem of modern oncology. The results of the study of the anti-PD1 monoclonal antibody pembrolizumab were a real breakthrough in the treatment of NSCLC. In the KEYN0TE-001 study, the expression of PD-L1 on tumor cells was validated as a predictive biomarker of the drug's efficiency. Pembrolizumab demonstrated the possibility of achieving long-term objective responses, and a 4-year 0S with all histological types in the subgroup of pre-treated patients with PD-L1 expression> 50% was 24.8% and 15.6% in the PD-L1> 1% group. In a phase 2/3 randomized study KEYN0TE-10 in the 2nd line treatment of NSCLC with PD-L1 expression > 1% pembrolizumab significantly increased life expectancy compared to docetaxel and confirmed the possibility of longterm duration of objective responses, even after cessation of treatment. Then the focus of research shifted to the 1st line of treatment. About 30% of patients with NSCLC have a high level of PD-L1 expression on tumor cells and demonstrate the most impressive response to pembrolizumab therapy. A randomized phase 3 study KEYN0TE-024 compared the effectiveness of pembrolizumab monotherapy with a standard platinum combination in patients with advanced NSCLC with a high level of PD-L1 expression without EGFR mutations or ALK translocation. Compared with the platinum doublet the administration of pembrolizumab significantly increased all estimated parameters, including the median of progression-free survival (mPFS was 10.3 months versus 6 months; HR = 0.50; 95% CI 0.37-0.68, p < 0.001), the objective response rate (ORR 44.8% versus 27.8%), duration of response (in the pembrolizumab arm the median was not reached, in the chemotherapy (CT) group - 6.3 months). Despite the approved crossover, the use of pembrolizumab in the 1st line of treatment more than doubled the life expectancy of NSCLC patients with high PD-L1 expression as compared to CT: the median overall survival (OS) was 30.0 months versus 14.2 months (HR = 0.63, p = 0.002), 1-year OS 70.3% versus 54.8%; 2-year OS - 51.5% versus 34.5%. The remaining population to study were untreated patients with any level of PD-L1 expression. A randomized phase 3 study KEYNOTE-189 evaluated the effectiveness of adding pembrolizumab to the platinum combination in the 1st line treatment of non-squamous NSCLC without EGFR and ALK mutations with any PD-L1 expression. The addition of pembrolizumab to the standard 1st line CT significantly increased all estimated efficacy indicators including OS, PFS and ORR. After a median follow-up of 10.5 months the median OS in the pembrolizumab combination group was not reached and in CT group was 11.3 months. The estimated 12-months survival was 69.2% and 49.4% respectively (HR = 0.49; 95% CI 0.38-0,64; p <0.001). The median PFS was 8.8 months versus 4.9 months, alive 1 year without progression 34.1% and 17.3% of patients respectively (HR = 0.52; p <0.001). The ORR in the group with pembrolizumab reached 47.6% versus 18.9% in CT group, moreover the tumor regressions were much longer. Finally a randomized 3-phase study KEYN0TE-407 evaluated the effectiveness of adding pembrolizumab to 1st-line CT of NSCLC with squamous histology with any PD-L1 expression. As the first analysis showed, the addition of permboli-zumab significantly increased OS of patients with squamous NSCLC, median OS 15.9 months versus 11.3 months in the groups of pembrolizumab + CT and placebo + CT respectively (HR = 0.64; 95% CI 0,49-0.95; p = 0.0006), median PFS 6.4 months and 4.8 months respectively (HR = 0.56; 95% CI 0.450.70; p <0, 0001) and OrR 57.9% versus 38.4%, the median response duration 7.7 months versus 4.8 months. Thus, the convincing advantages of using pembrolizumab in 1st line therapy were demonstrated in 3 randomized phase 3 studies: in monotherapy of NSCLC of any histological subtype with high PD-L1 expression, and in combination with CT in squamous and non-squamous hystologies regardless of the level of PD-L1 expression.

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