scholarly journals Analysis of Association between Intake of Red Wine Polyphenols and Oxidative Stress Parameters in the Liver of Growing Male Rats

2020 ◽  
Vol 10 (18) ◽  
pp. 6389
Author(s):  
Aleksandra Kołota ◽  
Dominika Głąbska ◽  
Michał Oczkowski ◽  
Joanna Gromadzka-Ostrowska
Keyword(s):  
Red Wine ◽  
Sinapic Acid ◽  
Protein Carbonyl ◽  
Male Rats ◽  
Carbonyl Groups ◽  
Coumaric Acid ◽  
Oxidative Stress Parameters ◽  
Protein Carbonyl Groups ◽  
Stress Parameters ◽  
Oxidative Effect

Red wine is a complex alcoholic beverage containing various substances, including those of a potential health-promoting properties, such as polyphenols, responsible for the sensory features of wine. Their potential positive influence is associated with possibility of antioxidative, anti-inflammatory, anticancer, immunomodulating, and antiallergenic effects, but at the same time, there is a possibility of their pro-oxidative effect. In spite of the fact that in adolescence alcohol may be highly damaging, as it may disturb the development, it is abused frequently. The aim of the study was to verify the association between red wine consumption as well as dietary polyphenol intake with wine and the oxidative stress parameters in the liver of growing male rats. The growing male Wistar rats were studied, while divided into three groups of six animals, receiving red wine in a solution characterized by 10% of ethanol content since 30th day of life, for two, four, and six weeks. The alcohol intake was controlled and the content of total phenolic compounds, selected phenolic acids (hydroxybenzoic acid, caffeic acid, p-coumaric acid, ferulic acid, and sinapic acid), total anthocyanidins and selected anthocyanins (cyanidin, cyanidin 3-glucoside, cyanidin 3-rutinoside, delphinidin, and pelargonidin) were assessed. At the same time, for the liver homogenates, the levels of Thiobarbituric Acid Reactive Substances (TBARS) and protein carbonyl groups were verified. The analysis revealed statistically significant influence of red wine intake, as well as of supply of phenolic acids (hydroxybenzoic acid, caffeic acid, p-coumaric acid, ferulic acid, and sinapic acid), and anthocyanins (cyanidin, cyanidin 3-glucoside, cyanidin 3-rutinoside, delphinidin, and pelargonidin) on TBARS and protein carbonyl groups level (R > 0.80; p < 0.05), but the influence was stated only for the period of two weeks. The obtained results may suggest pro-oxidative effect of both ethanol and polyphenols for the liver of the growing male rats. At the same time, for the periods of four and six weeks, no influence on TBARS and protein carbonyl groups level was observed (p > 0.05), which may allow to suppose an adaptive mechanism of the growing organism while the ethanol and polyphenols exposition is prolonged. Further studies are required to confirm the mechanism of the pro-oxidative effect of polyphenols contained in red wine for the liver of growing organism.

scholarly journals Protein carbonyl group content in patients affected by familiar chronic nail candidiasis

2003 ◽  
Vol 12 (4) ◽  
pp. 247-249 ◽  
Author(s):  
S. Gangemi ◽  
A. Saija ◽  
A. Tomaino ◽  
F. Cimino ◽  
R. A. Merendino ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Defense Mechanisms ◽  
Protein Carbonyl ◽  
Intercellular Adhesion Molecule ◽  
Carbonyl Groups ◽  
Intercellular Adhesion Molecule 1 ◽  
Protein Carbonyl Groups ◽  
Halide System ◽  
Reactive Nitrogen Intermediates ◽  
Hands And Feet

Familiar chronic nail candidiasis (FCNC) is a rare disorder characterized by early-onset infections caused by different species of Candida, restricted to the nail of the hands and feet, and associated with a low serum concentration of intercellular adhesion molecule 1. Host defense mechanisms against candidiasis require the cooperation of many immune cells through several candidacidal mechanisms, including oxygen-dependent killing mechanisms, mediated by a superoxide anion radical myeloperoxidase-H2O2-halide system, and reactive nitrogen intermediates. We analyzed protein carbonyl groups (considered a useful marker of oxidative stress) in the serum of patients belonging to a five-generation Italian family with an isolated form of FCNC.Serum protein carbonyl groups in FCNC patients were significantly lower than those measured in healthy donors.Also, if this hypothesis is merely speculative, we could suggest that the decreased circulating level of protein carbonyl groups in these patients is not a marker of a lower oxidative stress condition, but might be linked to a lower protease activity.

scholarly journals Behaviour of protein carbonyl groups in juvenile myocardial infarction

2013 ◽  
Vol 53 (4) ◽  
pp. 297-302 ◽  
Author(s):  
Gregorio Caimi ◽  
Baldassare Canino ◽  
Egle Incalcaterra ◽  
Eleonora Ferrera ◽  
Maria Montana ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Protein Carbonyl ◽  
Carbonyl Groups ◽  
Protein Carbonyl Groups

Increase in serum protein carbonyl groups is associated with more advanced stage of disease in multiple myeloma patients

Biomarkers ◽  
2011 ◽  
Vol 16 (8) ◽  
pp. 718-719 ◽  
Author(s):  
Caterina Musolino ◽  
Andrea Alonci ◽  
Alessandro Allegra ◽  
Antonella Saija ◽  
Giuseppa Penna ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Serum Protein ◽  
Protein Carbonyl ◽  
Advanced Stage ◽  
Carbonyl Groups ◽  
Stage Of Disease ◽  
Protein Carbonyl Groups

Activities of brain antioxidant enzymes, lipid and protein peroxidation

Open Medicine ◽  
2011 ◽  
Vol 6 (5) ◽  
pp. 588-594 ◽  
Author(s):  
Anna Łukaszewicz-Hussain
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Antioxidant Enzymes ◽  
Protein Carbonyl ◽  
Organophosphate Pesticides ◽  
Carbonyl Groups ◽  
Chronic Intoxication ◽  
Protein Carbonyl Groups ◽  
Protein Peroxidation ◽  
Antioxidant Enzymes Activities

AbstractOrganophosphate pesticides are known to induce oxidative stress and cause oxidative tissue damage, as has been reported in studies concerning acute and chronic intoxication with these compounds.Our objective was to investigate the activities of brain antioxidant enzymes and malonyldialdehyde, as well as the level of carbonyl groups, in rats sub-chronically intoxicated with chlorpyrifos at doses of 0.2, 2 and 5 mg per kg of body weight per day. It was found that chlorpyrifos induces change in brain antioxidant enzymes, such as superoxide dismutase, catalase and glutathione peroxidise, but to a different degree in comparison to proper control values; however, the elevated antioxidant enzymes activities failed to check lipid and protein peroxidation in the brains of rats. Thus, in sub-chronic intoxication with chlorpyrifos, as evidenced by increased level of malonyldialdehyde and carbonyl groups, oxidative stress is induced.Measurements of protein carbonyl groups appeared to give more consistent responses in the rats’ brains when compared to the malonyldialdehyde level after sub-chronic chlorpyrifos treatment.

Decrease in Serum Protein Carbonyl Groups Concentration and Maintained Hyperhomocysteinemia in Patients Undergoing Bariatric Surgery

2008 ◽  
Vol 19 (3) ◽  
pp. 321-326 ◽  
Author(s):  
T. Sledzinski ◽  
E. Goyke ◽  
R. T. Smolenski ◽  
Z. Sledzinski ◽  
J. Swierczynski
Keyword(s):  
Bariatric Surgery ◽  
Serum Protein ◽  
Protein Carbonyl ◽  
Carbonyl Groups ◽  
Protein Carbonyl Groups

scholarly journals Effects of Transport and Altitude on Hormones and Oxidative Stress Parameters in Sheep

2020 ◽  
Author(s):  
Hilal Tozlu Çelık ◽  
Fatih Ahmet Aslan ◽  
Diler Us Altay ◽  
Metehan Eser Kahvecı ◽  
Kalbiye Konanç ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sea Level ◽  
Live Weight ◽  
Protein Carbonyl ◽  
Stress Effects ◽  
Oxidative Stress Parameters ◽  
Transport Stress ◽  
And Oxidative Stress ◽  
Stress Parameters ◽  
Made In

AbstractWith this study, it was aimed to determine the stress effects that can be caused by transporting and altitude in sheep. Karayaka sheep were used in the study. The live weight of the sheep (n=30) while hungry was determined before transport and sea level. Average live weight was determined as 55.64 ± 4.66 kg. Blood samples were collected just before (sea level) and just after transport (1500 meters above sea level). Transportation distance was approximately 182 km and duration was 5 hours. According to the findings, cortisol was not affected by transport stress and altitude (p>0.05) and Triiyodotironin (T3) (p<0.039) and Tyrosine (T4) (p<0.000) were affected significantly. Malondialchehyche (MDA), which is one of the oxidative stress parameters, was significantly affected (p<0.039) and Protein Carbonyl (PC) values were not affected by transport and altitude (p>0.184). As a result of this study, it was determined that transportation and altitude in sheep causes stress. Stress-reducing measures should be taken in the exposure of sheep to altitude differences and in transportation. Antioxidant nutritional supplements should be made in order not to negatively affect the meat quality in sheep.

Effects of combined exposure to heat and psychological stress on oxidative stress parameters of adult male rats

2021 ◽  
Author(s):  
Faezeh Abbasi Balochkhaneh ◽  
Somayeh Farhang Dehghan ◽  
Abbas Haghparast ◽  
Mohammad Hossein Vaziri ◽  
Mehrdad Helmi Kohanehshari ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Psychological Stress ◽  
Adult Male ◽  
Male Rats ◽  
Combined Exposure ◽  
Oxidative Stress Parameters ◽  
Stress Parameters
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