scholarly journals Cascaded Regression-Based Segmentation of Cardiac CT under Probabilistic Correspondences

2020 ◽  
Vol 10 (14) ◽  
pp. 4947
Author(s):  
Jang Pyo Bae ◽  
Malinda Vania ◽  
Siyeop Yoon ◽  
Sojeong Cheon ◽  
Chang Hwan Yoon ◽  
...  

The creation of 3D models for cardiac mapping systems is time-consuming, and the models suffer from issues with repeatability among operators. The present study aimed to construct a double-shaped model composed of the left ventricle and left atrium. We developed cascaded-regression-based segmentation software with probabilistic point and appearance correspondence. Group-wise registration of point sets constructs the point correspondence from probabilistic matches, and the proposed method also calculates appearance correspondence from these probabilistic matches. Final point correspondence of group-wise registration constructed independently for three surfaces of the double-shaped model. Stochastic appearance selection of cascaded regression enables the effective construction in the aspect of memory usage and computation time. The two correspondence construction methods of active appearance models were compared in terms of the paired segmentation of the left atrium (LA) and left ventricle (LV). The proposed method segmented 35 cardiac CTs in six-fold cross-validation, and the symmetric surface distance (SSD), Hausdorff distance (HD), and Dice coefficient (DC), were used for evaluation. The proposed method produced 1.88 ± 0.37 mm of LV SSD, 2.25 ± 0.51 mm* of LA SSD, and 2.06 ± 0.34 mm* of the left heart (LH) SSD. Additionally, DC was 80.45% ± 4.27%***, where * p < 0.05, ** p < 0.01, and *** p < 0.001. All p values derive from paired t-tests comparing iterative closest registration with the proposed method. In conclusion, the authors developed a cascaded regression framework for 3D cardiac CT segmentation.

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Drasutiene ◽  
V Janusauskas ◽  
G Speziali ◽  
D Zakarkaite ◽  
M Budra ◽  
...  

Abstract Introduction Various minimally invasive mitral valve (MV) repair techniques are available to treat degenerative mitral regurgitation (MR). Transapical implantation of artificial chordae on a beating heart is performed using the NeoChord DS1000 device with real-time TEE guidance. Purpose 1)To assess preoperative and the mid-term follow-up echocardiographic data in patients after MV repair using the NeoChord DS1000 device; 2)to investigate the changes of left ventricle (LV), left atrium (LA) and mitral annulus dimensions during the follow-up period; 3)to assess the difference of baseline echocardiographic parameters between successful and not-successful (severe residual MR) MV repair groups; 4)to identify the preoperative echocardiographic variables that may be associated with recurrence of MR at mid-term follow. Methods All patients after transapical MV repair with Neochord implantation in Vilnius University hospital were prospectively entered into the study. The acquired preoperative and follow-up echocardiographic datasets were analysed. According to the residual MR at follow-up, patients were stratified to 2 groups: group A – successful durable MV repair (residual MR ≤2); group B – MV repair failure (recurrence of severe MR or reintervention). Values were expressed as Mean±SD. Univariable regression analysis was used to identify anatomical predictors of residual MR. Results 53 (70.67%) patients had a residual MR ≤2 (Group A) and 22 (29.33%) residual MR≥2+ (Group B) at 26±6 months follow-up. At baseline, Group B patients had significantly larger left ventricle end diastolic diameter (LVEDD) (mean difference 5.67±1.29mm, p&lt;0.0001) left ventricle end systolic diameter (LVESD) (mean difference 4.08±1.57mm, p=0.012), LA volume index (mean difference 21.57±5.003 p&lt;0.0001) and higher systolic pulmonary pressure values (mean difference 10.46±3.34, p&lt;0.003) compared with group A. Overall, a significant reduction in LA volume index (mean change 15.69±4.15ml/m2, p&lt;0.001), LA diameter (mean change 3.15±1.24, p=0.012), LV diameter (mean change in LVEDD 4.78±0.88mm p&lt;0.000) was observed at 24 months follow up. There was no significant changes in MV annular parameters at follow up. Left atrium volume (OR 1.018; 95% CI 1.006–1.035; p=0.009), left atrium volume index (OR 1.038; 95% CI 1.013–1.072; p=0.010), LVEDD (OR 1.201; 95% CI 1.088–1.353; p=0.0008), LVESD (OR 1.122; 95% CI 1.02–1.248); p=0.0236) and sPAP (OR 1.418; 95% CI 1.139–2.016; p=0.0014) were all significantly associated with the worse outcome (MR &gt;2) after mini-invasive MV repair in univariable regression analysis. Conclusions Minimaly invasive MV repair with Neochord system on beating heart is effective in patients with degenerative MR. Baseline echocardiographic characteristics predictive for a worse middle term outcome are mainly related to LV and LA remodeling. Reverse remodeling of LV and LA is observed during the follow-up period with no significant changes in MV annulus. Funding Acknowledgement Type of funding source: None


2003 ◽  
Author(s):  
Hans C. van Assen ◽  
Rob J. van der Geest ◽  
Mikhail G. Danilouchkine ◽  
Hildo J. Lamb ◽  
Johan H. C. Reiber ◽  
...  

2009 ◽  
Vol 11 (3) ◽  
pp. 250-256 ◽  
Author(s):  
S. Caselli ◽  
E. Canali ◽  
M. L. Foschi ◽  
D. Santini ◽  
E. Di Angelantonio ◽  
...  

2013 ◽  
Vol 44 (5) ◽  
pp. e341-e342 ◽  
Author(s):  
Arnaud Rodriguez ◽  
François Roubertie ◽  
Matthieu Thumerel ◽  
Jacques Jougon

2011 ◽  
Vol 5 ◽  
pp. 909-913
Author(s):  
Stanisław Ostrowski ◽  
Anna Marcinkiewicz ◽  
Anna Kośmider ◽  
Witold Pawłowski ◽  
Alicja Nowakowska ◽  
...  
Keyword(s):  

Radiology ◽  
1965 ◽  
Vol 85 (4) ◽  
pp. 658-662 ◽  
Author(s):  
K. Ostergaard Petersen ◽  
G. Harrington ◽  
Nils Magnus Ohlsson ◽  
Guido Ascanio ◽  
M. J. Oppenheimer

2011 ◽  
Vol 12 (8) ◽  
pp. 584-584 ◽  
Author(s):  
Jesús Zarauza ◽  
Jose A. Vázquez de Prada ◽  
Jose M. Cuesta ◽  
Pilar Ortiz ◽  
Salvador Diez-Aja ◽  
...  

Author(s):  
Jérôme Limido ◽  
Mohamed Trabia ◽  
Shawoon Roy ◽  
Brendan O’Toole ◽  
Richard Jennings ◽  
...  

A series of experiments were performed to study plastic deformation of metallic plates under hypervelocity impact at the University of Nevada, Las Vegas (UNLV) Center for Materials and Structures using a two-stage light gas gun. In these experiments, cylindrical Lexan projectiles were fired at A36 steel target plates with velocities range of 4.5–6.0 km/s. Experiments were designed to produce a front side impact crater and a permanent bulging deformation on the back surface of the target without inducing complete perforation of the plates. Free surface velocities from the back surface of target plate were measured using the newly developed Multiplexed Photonic Doppler Velocimetry (MPDV) system. To simulate the experiments, a Lagrangian-based smooth particle hydrodynamics (SPH) is typically used to avoid the problems associated with mesh instability. Despite their intrinsic capability for simulation of violent impacts, particle methods have a few drawbacks that may considerably affect their accuracy and performance including, lack of interpolation completeness, tensile instability, and existence of spurious pressure. Moreover, computational time is also a strong limitation that often necessitates the use of reduced 2D axisymmetric models. To address these shortcomings, IMPETUS Afea Solver® implemented a newly developed SPH formulation that can solve the problems regarding spurious pressures and tensile instability. The algorithm takes full advantage of GPU Technology for parallelization of the computation and opens the door for running large 3D models (20,000,000 particles). The combination of accurate algorithms and drastically reduced computation time now makes it possible to run a high fidelity hypervelocity impact model.


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