scholarly journals Antimicrobial Poly (methyl methacrylate) with Silver Nanoparticles for Dentistry: A Systematic Review

2020 ◽  
Vol 10 (11) ◽  
pp. 4007 ◽  
Author(s):  
Flores-Arriaga Juan Carlos ◽  
García-Contreras Rene ◽  
Villanueva-Sánchez Germán ◽  
Acosta-Torres Laura Susana
Keyword(s):  
Silver Nanoparticles ◽  
Methyl Methacrylate ◽  
Biofilm Formation ◽  
Dental Materials ◽  
Etiologic Factor ◽  
Poly Methyl Methacrylate ◽  
Oral Infections ◽  
Dental Prostheses ◽  
Antibacterial And Antifungal ◽  
Dental Applications

Poly(methyl methacrylate) (PMMA) is a widely used polymer for dental applications, and it is mainly used in the fabrication of dental prostheses. In an increasing number of these applications, the risk of suffering bacterial or fungal infection is higher than 60% among oral-prosthesis users. Some authors have reported the failure of other implants in the human body due to biofilm formation on the surface (mainly for total hip implants). In the dental field, the formation of bacterial and fungal biofilms on prosthesis’s surface is the etiologic factor for stomatitis, mainly caused by Candida albicans and bacteria such as Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa and Enterococcus faecalis, as well as many others. The antibacterial and antifungal properties of silver nanoparticles (AgNPs) have been widely reported, and their use in dental materials can prevent oral infections, such as candidiasis and stomatitis, and promote better oral health in dental-prosthesis users. They can even be used in other biomedical applications that require controlling biofilm formation on surfaces. In this review, the reported studies that use composites of PMMA and AgNPs (PMMA-AgNPs) for dental applications are listed and checked, with the aim of gaining a wider perspective of the use and application of this approach in the dental field.

scholarly journals Al2O3 Preforms Infiltrated with Poly(methyl methacrylate) for Dental Prosthesis Manufacturing

2021 ◽  
Vol 11 (16) ◽  
pp. 7583
Author(s):  
Olimpia Crispim da Silveira ◽  
Alisson Mendes Rodrigues ◽  
Maziar Montazerian ◽  
Hélio de Lucena Lira ◽  
Francesco Baino ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Mechanical Characteristics ◽  
Great Promise ◽  
Biocompatible Polymers ◽  
Interpenetrating Network ◽  
Poly Methyl Methacrylate ◽  
Dental Crowns ◽  
Dental Prostheses ◽  
Dental Applications ◽  
Potential Use

The combination of biocompatible polymers and ceramics shows great promise in the development of composites with suitable mechanical properties for dental applications. In an attempt to further expand this research line, Al2O3 commercial powders (Vitro-ceram, Alglass, In-ceram) were sintered at 1400 °C for 2 h and infiltrated with poly(methyl methacrylate) for potential use in dental prostheses. The infiltration was performed using a homemade apparatus under a pressure of 7 bar for 6 and 12 h. The microstructure (studied using a scanning electron microscope), Archimedes density, 3-point bending flexural strength and Vickers hardness of the prepared composites were assessed and quantitatively compared. In general, microstructural analyses showed ceramic- and polymer-based interpenetrating network in all materials. The preforms infiltrated for 12 h showed superior properties; among them, the Vitro-ceram-based composite also demonstrated a near-zero open porosity and optimum mechanical characteristics. Specifically, its density, strength and hardness were 2.6 ± 0.07 g/cm3, 119.3 ± 5.0 MPa and 1055.1 ± 111.0 HV, respectively, passing the acceptance criteria of ISO 6872 and making it suitable for consideration as a metal-free structure for dental crowns and fixed partial prostheses until three anterior units.

scholarly journals Silver Nanoparticles Addition in Poly(Methyl Methacrylate) Dental Matrix: Topographic and Antimycotic Studies

2019 ◽  
Vol 20 (19) ◽  
pp. 4691 ◽  
Author(s):  
Valeria De Matteis ◽  
Mariafrancesca Cascione ◽  
Chiara Cristina Toma ◽  
Giovanni Albanese ◽  
Maria Luisa De Giorgi ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Methyl Methacrylate ◽  
Chemical Properties ◽  
Pathogenic Yeast ◽  
Poly Methyl Methacrylate ◽  
Oral Infections ◽  
Yeast Viability ◽  
Treatment And Prevention ◽  
Opportunistic Pathogenic ◽  
Citrate Capping

The widespread use of nanoparticles (NPs) in medical devices has opened a new scenario in the treatment and prevention of many diseases and infections owing to unique physico-chemical properties of NPs. In this way, silver nanoparticles (AgNPs) are known to have a strong antimicrobial activity, even at low concentrations, due to their ability to selectively destroy cellular membranes. In particular, in the field of dental medicine, the use of AgNPs in different kinds of dental prosthesis matrixes could be a fundamental tool in immunodepressed patients that suffer of different oral infections. Candida albicans (C. albicans), an opportunistic pathogenic yeast with high colonization ability, is one of the causative agents of oral cavity infection. In our work, we added monodispersed citrate-capping AgNPs with a size of 20 nm at two concentrations (3 wt% and 3.5 wt%) in poly(methyl methacrylate) (PMMA), the common resin used to develop dental prostheses. After AgNPs characterization, we evaluated the topographical modification of PMMA and PMMA with the addition of AgNPs by means of atomic force microscopy (AFM), showing the reduction of surface roughness. The C. albicans colonization on PMMA surfaces was assessed by the Miles and Misra technique as well as by scanning electron microscopy (SEM) at 24 h and 48 h with encouraging results on the reduction of yeast viability after AgNPs exposure.

Green synthesised silver nanoparticles incorporated electrospun poly(methyl methacrylate) nanofibers with different architectures for ophthalmologic alternatives

2021 ◽  
Vol 36 (2) ◽  
pp. 93-110
Author(s):  
Princy Philip ◽  
Tomlal Jose ◽  
Sarath KS ◽  
Sunny Kuriakose
Keyword(s):  
Silver Nanoparticles ◽  
Methyl Methacrylate ◽  
Antibacterial Properties ◽  
Analytical Techniques ◽  
Morphological Properties ◽  
Gram Positive ◽  
Gram Negative ◽  
Poly Methyl Methacrylate ◽  
Antimicrobial Studies ◽  
Eye Problems

Silver nanoparticles with 5–10 nm diameters are synthesised using Couroupita guianensis flower extract. The synthesised silver nanoparticles found to show good antimicrobial activity against gram negative and gram positive bacteria. Poly(methyl methacrylate) nanofibers with pristine, surface roughened and coaxial hollow forms are prepared by electrospinning. The structural and morphological properties of these pure and structurally modified poly(methyl methacrylate) nanofibers are evidenced by various analytical techniques. The antimicrobial studies of poly(methyl methacrylate) nanofibers having different architectures incorporated with silver nanoparticles are carried out. It is found that, all the three forms of poly(methyl methacrylate) nanofibers incorporated with silver nanoparticles show antibacterial properties against both gram positive and gram negative bacteria. Among these, surface roughened poly(methyl methacrylate) nanofibers incorporated with silver nanoparticles show highest antibacterial activity than the other two structural forms. The present study offers an alternative to the existing optical lenses. People especially those who suffer from eye problems can protect their eyes in a better way from infectious agents by wearing optical lens made from C. guianensis stabilised silver nanoparticles incorporated poly(methyl methacrylate) nanofibers than that made from pure poly(methyl methacrylate) nanofibers or films.

scholarly journals Graphene-Doped Poly (Methyl-Methacrylate) (Pmma) Implants: A Micro-CT and Histomorphometrical Study in Rabbits

2021 ◽  
Vol 22 (3) ◽  
pp. 1441
Author(s):  
Antonio Scarano ◽  
Tiziana Orsini ◽  
Fabio Di Carlo ◽  
Luca Valbonetti ◽  
Felice Lorusso
Keyword(s):  
Methyl Methacrylate ◽  
Dental Implant ◽  
Animal Studies ◽  
White Male ◽  
Biological Response ◽  
Medullary Canal ◽  
Poly Methyl Methacrylate ◽  
Titanium Surfaces ◽  
Dental Applications

Background—the graphene-doping procedure represents a useful procedure to improve the mechanical, physical and biological response of several Polymethyl methacrylate (PMMA)-derived polymers and biomaterials for dental applications. The aim of this study was to evaluate osseointegration of Graphene doped Poly(methyl methacrylate) (GD-PMMA) compared with PMMA as potential materials for dental implant devices. Methods—eighteen adult New Zealand white male rabbits with a mean weight of approx. 3000 g were used in this research. A total of eighteen implants of 3.5 mm diameter and 11 mm length in GD-PMMA and eighteen implants in PMMA were used. The implants were placed into the articular femoral knee joint. The animals were sacrificed after 15, 30 and 60 days and the specimens were evaluated by µCT and histomorphometry. Results—microscopically, all 36 implants, 18 in PMMA and 18 in DG-PMMA were well-integrated into the bone. The implants were in contact with cortical bone along the upper threads, while the lower threads were in contact with either newly formed bone or with marrow spaces. The histomorphometry and µCT evaluation showed that the GP-PMMA and PMMA implants were well osseointegrated and the bone was in direct contact with large portions of the implant surfaces, including the space in the medullary canal. Conclusions—in conclusion, the results suggest that GD-PMMA titanium surfaces enhance osseointegration in rabbit femurs. This encourages further research to obtain GD-PMMA with a greater radiopacity. Also, further in vitro and vivo animal studies are necessary to evaluate a potential clinical usage for dental implant applications.

Indication of formation of charge density waves in silver nanoparticles dispersed poly(methyl methacrylate) thin films

2011 ◽  
Vol 161 (13-14) ◽  
pp. 1390-1399 ◽  
Author(s):  
Manisree Majumder ◽  
Aloke Kumar Chakraborty ◽  
Bipul Biswas ◽  
Avijit Chowdhury ◽  
Biswanath Mallik
Keyword(s):  
Thin Films ◽  
Silver Nanoparticles ◽  
Methyl Methacrylate ◽  
Charge Density ◽  
Charge Density Waves ◽  
Density Waves ◽  
Poly Methyl Methacrylate

scholarly journals Chemical Modification of Cellulose Microfibres to Reinforce Poly(methyl methacrylate) Used for Dental Application

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3807 ◽  
Author(s):  
Joanna Taczała ◽  
Jacek Sawicki ◽  
Joanna Pietrasik
Keyword(s):  
Methyl Methacrylate ◽  
Mechanical Performance ◽  
Average Length ◽  
General Procedure ◽  
Dental Materials ◽  
Poly Methyl Methacrylate ◽  
Active Filler ◽  
The Matrix ◽  
Dental Acrylic ◽  
Good Potential

The mechanical properties of dental acrylic resins have to be improved in the case of a thin denture plate. This can be achieved by cellulose addition, playing the role of active filler. But to provide the excellent dispersion of cellulose microfibres within the hydrophobic polymer matrix, its surface has to be modified. Cellulose microfibres with average length from 8 to 30 μm were modified with octyltriethoxysilane and (3-methacryloxypropyl)methyldimethoxysilane. The latter also participated in the polymerisation reaction of methyl methacrylate. Dental composites were prepared following the general procedure provided by the supplier. The successful modification of the microfibres led to the improved compatibility of the cellulose and poly(methyl methacrylate). The fibres after modification were uniformly distributed within the matrix, resulting in the improved mechanical performance of obtained materials. Cellulose microfibres are good candidates for the dental materials to be used as the active filler. The simple and straightforward approach for the cellulose modifications with silanes provides good potential for its future practical application.

scholarly journals Surface Functionalization of an Aluminum Alloy to Generate an Antibiofilm Coating Based on Poly(Methyl Methacrylate) and Silver Nanoparticles

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2747 ◽  
Author(s):  
Lisa Muñoz ◽  
Laura Tamayo ◽  
Miguel Gulppi ◽  
Franco Rabagliati ◽  
Marcos Flores ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Aluminum Alloy ◽  
Methyl Methacrylate ◽  
In Situ Polymerization ◽  
Polymerization Reaction ◽  
Experimental Protocol ◽  
Poly Methyl Methacrylate ◽  
Methacrylate Monomer ◽  
Methyl Methacrylate Monomer

An experimental protocol was studied to improve the adhesion of a polymeric poly(methyl methacrylate) coating that was modified with silver nanoparticles to an aluminum alloy, AA2024. The nanoparticles were incorporated into the polymeric matrix to add the property of inhibiting biofilm formation to the anticorrosive characteristics of the film, thus also making the coating antibiocorrosive. The protocol consists of functionalizing the surface through a pseudotransesterification treatment using a methyl methacrylate monomer that bonds covalently to the surface and leaves a terminal double bond that promotes and directs the polymerization reaction that takes place in the process that follows immediately after. This results in more compact and thicker poly(methyl methacrylate) (PMMA) coatings than those obtained without pseudotransesterification. The poly(methyl methacrylate) matrix modified with nanoparticles was obtained by incorporating both the nanoparticles and the methyl methacrylate in the reactor. The in situ polymerization involved combining the pretreated AA2024 specimens combined with the methyl methacrylate monomer and AgNps. The antibiofilm capacity of the coating was evaluated against P. aeruginosa, with an excellent response. Not only did the presence of bacteria decrease, but the formation of the exopolymer subunits was 99.99% lower than on the uncoated aluminum alloy or the alloy coated with unmodified poly(methyl methacrylate). As well and significantly, the potentiodynamic polarization measurements indicate that the PMMA-Ag coating has a good anticorrosive property in a 0.1-M NaCl medium.

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