scholarly journals Conventional and Deep Learning Methods for Skull Stripping in Brain MRI

2020 ◽  
Vol 10 (5) ◽  
pp. 1773 ◽  
Author(s):  
Hafiz Zia Ur Rehman ◽  
Hyunho Hwang ◽  
Sungon Lee

Skull stripping in brain magnetic resonance volume has recently been attracting attention due to an increased demand to develop an efficient, accurate, and general algorithm for diverse datasets of the brain. Accurate skull stripping is a critical step for neuroimaging diagnostic systems because neither the inclusion of non-brain tissues nor removal of brain parts can be corrected in subsequent steps, which results in unfixed error through subsequent analysis. The objective of this review article is to give a comprehensive overview of skull stripping approaches, including recent deep learning-based approaches. In this paper, the current methods of skull stripping have been divided into two distinct groups—conventional or classical approaches, and convolutional neural networks or deep learning approaches. The potentials of several methods are emphasized because they can be applied to standard clinical imaging protocols. Finally, current trends and future developments are addressed giving special attention to recent deep learning algorithms.

2019 ◽  
Vol 9 (3) ◽  
pp. 569 ◽  
Author(s):  
Hyunho Hwang ◽  
Hafiz Zia Ur Rehman ◽  
Sungon Lee

Skull stripping in brain magnetic resonance imaging (MRI) is an essential step to analyze images of the brain. Although manual segmentation has the highest accuracy, it is a time-consuming task. Therefore, various automatic segmentation algorithms of the brain in MRI have been devised and proposed previously. However, there is still no method that solves the entire brain extraction problem satisfactorily for diverse datasets in a generic and robust way. To address these shortcomings of existing methods, we propose the use of a 3D-UNet for skull stripping in brain MRI. The 3D-UNet was recently proposed and has been widely used for volumetric segmentation in medical images due to its outstanding performance. It is an extended version of the previously proposed 2D-UNet, which is based on a deep learning network, specifically, the convolutional neural network. We evaluated 3D-UNet skull-stripping using a publicly available brain MRI dataset and compared the results with three existing methods (BSE, ROBEX, and Kleesiek’s method; BSE and ROBEX are two conventional methods, and Kleesiek’s method is based on deep learning). The 3D-UNet outperforms two typical methods and shows comparable results with the specific deep learning-based algorithm, exhibiting a mean Dice coefficient of 0.9903, a sensitivity of 0.9853, and a specificity of 0.9953.


Drones ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 52
Author(s):  
Thomas Lee ◽  
Susan Mckeever ◽  
Jane Courtney

With the rise of Deep Learning approaches in computer vision applications, significant strides have been made towards vehicular autonomy. Research activity in autonomous drone navigation has increased rapidly in the past five years, and drones are moving fast towards the ultimate goal of near-complete autonomy. However, while much work in the area focuses on specific tasks in drone navigation, the contribution to the overall goal of autonomy is often not assessed, and a comprehensive overview is needed. In this work, a taxonomy of drone navigation autonomy is established by mapping the definitions of vehicular autonomy levels, as defined by the Society of Automotive Engineers, to specific drone tasks in order to create a clear definition of autonomy when applied to drones. A top–down examination of research work in the area is conducted, focusing on drone navigation tasks, in order to understand the extent of research activity in each area. Autonomy levels are cross-checked against the drone navigation tasks addressed in each work to provide a framework for understanding the trajectory of current research. This work serves as a guide to research in drone autonomy with a particular focus on Deep Learning-based solutions, indicating key works and areas of opportunity for development of this area in the future.


2021 ◽  
Vol 11 (22) ◽  
pp. 10982
Author(s):  
Lakpa Dorje Tamang ◽  
Byung Wook Kim

Unprecedented breakthroughs in the development of graphical processing systems have led to great potential for deep learning (DL) algorithms in analyzing visual anatomy from high-resolution medical images. Recently, in digital pathology, the use of DL technologies has drawn a substantial amount of attention for use in the effective diagnosis of various cancer types, especially colorectal cancer (CRC), which is regarded as one of the dominant causes of cancer-related deaths worldwide. This review provides an in-depth perspective on recently published research articles on DL-based CRC diagnosis and prognosis. Overall, we provide a retrospective synopsis of simple image-processing-based and machine learning (ML)-based computer-aided diagnosis (CAD) systems, followed by a comprehensive appraisal of use cases with different types of state-of-the-art DL algorithms for detecting malignancies. We first list multiple standardized and publicly available CRC datasets from two imaging types: colonoscopy and histopathology. Secondly, we categorize the studies based on the different types of CRC detected (tumor tissue, microsatellite instability, and polyps), and we assess the data preprocessing steps and the adopted DL architectures before presenting the optimum diagnostic results. CRC diagnosis with DL algorithms is still in the preclinical phase, and therefore, we point out some open issues and provide some insights into the practicability and development of robust diagnostic systems in future health care and oncology.


2019 ◽  
Vol 1 (Supplement_1) ◽  
pp. i20-i21
Author(s):  
Min Zhang ◽  
Geoffrey Young ◽  
Huai Chen ◽  
Lei Qin ◽  
Xinhua Cao ◽  
...  

Abstract BACKGROUND AND OBJECTIVE: Brain metastases have been found to account for one-fourth of all cancer metastases seen in clinics. Magnetic resonance imaging (MRI) is widely used for detecting brain metastases. Accurate detection of the brain metastases is critical to design radiotherapy to treat the cancer and monitor their progression or response to the therapy and prognosis. However, finding metastases on brain MRI is very challenging as many metastases are small and manifest as objects of weak contrast on the images. In this work we present a deep learning approach integrated with a classification scheme to detect cancer metastases to the brain on MRI. MATERIALS AND METHODS: We retrospectively extracted 101 metastases patients, equal to 1535 metastases on 10192 slices of images in a total of 336 scans from our PACS and manually marked the lesions on T1-weighted contrast enhanced MRI as the ground-truth. We then randomly separated the cases into training, validation, and test sets for developing and optimizing the deep learning neural network. We designed a 2-step computer-aided detection (CAD) pipeline by first applying a fast region-based convolutional neural network method (R-CNN) to sequentially process each slice of an axial brain MRI to find abnormal hyper-intensity that may correspond to a brain metastasis and, second, applying a random under sampling boost (RUSBoost) classification method to reduce the false positive metastases. RESULTS: The computational pipeline was tested on real brain images. A sensitivity of 97.28% and false positive rate of 36.25 per scan over the images were achieved by using the proposed method. CONCLUSION: Our results demonstrated the deep learning-based method can detect metastases in very challenging cases and can serve as CAD tool to help radiologists interpret brain MRIs in a time-constrained environment.


2020 ◽  
Vol 14 ◽  
Author(s):  
Chenyi Zeng ◽  
Lin Gu ◽  
Zhenzhong Liu ◽  
Shen Zhao

In recent years, there have been multiple works of literature reviewing methods for automatically segmenting multiple sclerosis (MS) lesions. However, there is no literature systematically and individually review deep learning-based MS lesion segmentation methods. Although the previous review also included methods based on deep learning, there are some methods based on deep learning that they did not review. In addition, their review of deep learning methods did not go deep into the specific categories of Convolutional Neural Network (CNN). They only reviewed these methods in a generalized form, such as supervision strategy, input data handling strategy, etc. This paper presents a systematic review of the literature in automated multiple sclerosis lesion segmentation based on deep learning. Algorithms based on deep learning reviewed are classified into two categories through their CNN style, and their strengths and weaknesses will also be given through our investigation and analysis. We give a quantitative comparison of the methods reviewed through two metrics: Dice Similarity Coefficient (DSC) and Positive Predictive Value (PPV). Finally, the future direction of the application of deep learning in MS lesion segmentation will be discussed.


Intensification in the occurrence of brain diseases and the need for the initial diagnosis for ailments like Tumor, Alzheimer’s, Epilepsy and Parkinson’s has riveted the attention of researchers. Machine learning practices, specifically deep learning, is considered as a beneficial diagnostic tool. Deep learning approaches to neuroimaging will assist computer-aided analysis of neurological diseases. Feature extraction of neuroimages carried out using Artificial Neural Networks leads to better diagnoses. In this study, all the brain diseases are revisited to consolidate the methodologies carried out by various authors in the literature.


Brain tumor is an unusual intensification of cells inside the skull. The brain MRI scanned images is segmented to extract brain tumor to analyze type and depth of tumor. In order to reduce the time consumption of brain tumor extraction, an automatic method for detection of brain tumor is highly recommended. Deep machine learning methods are used for automatic detection of the brain tumor in soft tissues at an early stage which involves the following stages namely: image pre-processing, clustering and optimization. This paper addresses previously adduced pre-processing (Skull stripping, Contrast stretching, clustering (k-Means, Fuzzy c-means) and optimization (Cuckoo search optimization, Artificial Bee Colony optimization) strategies for abnormal brain tumor detection from MRI brain images. Performance evaluation is done based on computational time of clustering output and optimization algorithms are analyzed in terms of sensitivity, specificity, and accuracy


2020 ◽  
pp. 40-175
Author(s):  
Edmund T. Rolls

The brain processes involved in visual object recognition are described. Evidence is presented that what is computed are sparse distributed representations of objects that are invariant with respect to transforms including position, size, and even view in the ventral stream towards the inferior temporal visual cortex. Then biologically plausible unsupervised learning mechanisms that can perform this computation are described that use a synaptic modification rule what utilises a memory trace. These are compared with deep learning and other machine learning approaches that require supervision.


2021 ◽  
Vol 23 (07) ◽  
pp. 516-529
Author(s):  
Reshma L ◽  
◽  
Sai Priya Nalluri ◽  
Priya R Sankpal ◽  
◽  
...  

In this paper, a user-friendly system has been developed which will provide the result of medical analysis of digital images like magnetization resonance of image scan of the brain for detection and classification of dementia. The small structural differences in the brain can slowly and gradually become a major disease like dementia. The progression of dementia can be slowed when identified early. Hence, this paper aims at developing a robust system for classification and identifying dementia at the earliest. The method used in this paper for initial disclosure and diagnosis of dementia is deep learning since it can give important results in a shorter period of time. Deep Learning methods such as K-means clustering, Pattern Recognition, and Multi-class Support Vector Machine (SVM) have been used to classify different stages of dementia. The goal of this study is to provide a user interface for deep learning-based dementia classification using brain magnetic resonance imaging data. The results show that the created method has an accuracy of 96% and may be utilized to detect people who have dementia or are in the early stages of dementia.


2018 ◽  
Vol 17 (1) ◽  
pp. 115-130 ◽  
Author(s):  
Ricardo Pizarro ◽  
Haz-Edine Assemlal ◽  
Dante De Nigris ◽  
Colm Elliott ◽  
Samson Antel ◽  
...  

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