scholarly journals Valorisation of Exhausted Olive Pomace by an Eco-Friendly Solvent Extraction Process of Natural Antioxidants

Antioxidants ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 1010 ◽  
Author(s):  
Irene Gómez-Cruz ◽  
Cristóbal Cara ◽  
Inmaculada Romero ◽  
Eulogio Castro ◽  
Beatriz Gullón
Keyword(s):  
Bioactive Compounds ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Industrial Applications ◽  
Antioxidant Compounds ◽  
Olive Pomace ◽  
Operational Parameters ◽  
Food Borne ◽  
High Antioxidant Activity ◽  
Gallic Acid Equivalent

Exhausted olive pomace (EOP) is the waste generated from the drying and subsequent extraction of residual oil from the olive pomace. In this work, the effect of different aqueous solvents on the recovery of antioxidant compounds from this lignocellulosic biomass was assessed. Water extraction was selected as the best option for recovering bioactive compounds from EOP, and the influence of the main operational parameters involved in the extraction was evaluated by response surface methodology. Aqueous extraction of EOP under optimised conditions (10% solids, 85 ºC, and 90 min) yielded an extract with concentrations (per g EOP) of phenolic compounds and flavonoids of 44.5 mg gallic acid equivalent and 114.9 mg rutin equivalent, respectively. Hydroxytyrosol was identified as the major phenolic compound in EOP aqueous extracts. Moreover, these extracts showed high antioxidant activity, as well as moderate bactericidal action against some food-borne pathogens. In general, these results indicate the great potential of EOP as a source of bioactive compounds, with potential uses in several industrial applications.

scholarly journals Enhanced Recovery of Antioxidant Compounds from Hazelnut (Corylus avellana L.) Involucre Based on Extraction Optimization: Phytochemical Profile and Biological Activities

Antioxidants ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 460 ◽  
Author(s):  
Rusu ◽  
Fizeșan ◽  
Pop ◽  
Gheldiu ◽  
Mocan ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Enhanced Recovery ◽  
Biological Activities ◽  
Natural Antioxidants ◽  
Antioxidant Compounds ◽  
Cancerous Cell ◽  
Wide Range ◽  
Quantitative Analyses ◽  
Corylus Avellana L

Tree nut by-products could contain a wide range of phytochemicals, natural antioxidants, which might be used as a natural source for dietary supplements. The aim of the present study was to evaluate the phenolic and sterolic composition, as well as the antioxidant and other biological activities, of hazelnut involucre (HI) extracts. Experimental designs were developed in order to select the optimum extraction conditions (solvent, temperature, time) using turbo-extraction by Ultra-Turrax for obtaining extracts rich in bioactive compounds. Qualitative and quantitative analyses were performed by LC-MS and LC-MS/MS and they revealed important amounts of individual polyphenols and phytosterols, molecules with antioxidant potential. The richest polyphenolic HI extract with the highest antioxidant activity by TEAC assay was further evaluated by other in vitro antioxidant tests (DPPH, FRAP) and enzyme inhibitory assays. Additionally, the cytotoxic and antioxidant effects of this extract on two cancerous cell lines and on normal cells were tested. This is the first study to analyze the composition of both hydrophilic and lipophilic bioactive compounds in HI extracts. Our findings reveal that this plant by-product presents strong biological activities, justifying further research, and it could be considered an inexpensive source of natural antioxidants for food, pharmaceutical, or cosmetic industry.

scholarly journals Valorization of Natural Antioxidants for Nutritional and Health Applications

2021 ◽  
Author(s):  
Pedro Ferreira-Santos ◽  
Zlatina Genisheva ◽  
Claudia Botelho ◽  
Cristina Rocha ◽  
José António Teixeira
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Chemical Properties ◽  
Health Benefit ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Extraction Methods ◽  
In Vivo Studies

The significant increase in the world population age, 47 years in 1950 to 73 years in 2020, resulted in an increase in aging related diseases as well as in degenerative diseases. In consequence, researchers have been focusing in the development of new therapies, with a particular emphasis on the use of compounds with antioxidant properties, namely phytochemicals, such as polyphenols and carotenoids. Several in vitro and in vivo studies have demonstrated the phytochemicals antioxidant capacity. Their use is broad, as they can be part of food supplements, medicine and cosmetics. The health benefit of antioxidant phytochemicals is an indisputable question. Phytochemical properties are highly influenced by the natural matrix as well as by extraction process, which have a key role. There are several extraction methods that can be applied depending on the chemical properties of the bioactive compounds. There is a wide range of solvents with different polarities, which allows a selective extraction of the desired target family of compounds. Greener technologies have the advantage to reduce extraction time and solvent quantity in comparison to the most traditional methods. This chapter will focus on the different green extraction strategies related to the recovery of antioxidant bioactive compounds from natural sources, their nutritional and health potential.

scholarly journals Correction: Gómez-Cruz et al. Valorisation of Exhausted Olive Pomace by an Eco-Friendly Solvent Extraction Process of Natural Antioxidants. Antioxidants 2020, 9, 1010

Antioxidants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 948
Author(s):  
Irene Gómez-Cruz ◽  
Cristóbal Cara ◽  
Inmaculada Romero ◽  
Eulogio Castro ◽  
Beatriz Gullón
Keyword(s):  
Solvent Extraction ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Olive Pomace

The author wishes to make the following correction to this paper [...]

scholarly journals Ekstraksi kulit petai sebagai sumber antioksidan alami dengan metode domestic microwave maceration

2018 ◽  
Vol 12 (2) ◽  
pp. 237
Author(s):  
A Agnes ◽  
Lois Olivia Widjaja ◽  
Aning Ayucitra ◽  
Nani Indraswati
Keyword(s):  
Free Radicals ◽  
Phenolic Compound ◽  
Ethanol Concentration ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Total Phenolic ◽  
Antioxidant Compounds ◽  
Solvent Ratio ◽  
Total Phenolic Compound ◽  
Radiation Time

Extraction of petai peels as natural antioxidants source by domestic microwave macerationPetai (Parkia speciosa) contains antioxidants that can prevent free radicals. Research also proves that petai is able to prevent and even overcome diseases because its seeds contain polyphenols and flavonoids which are known as antioxidant compounds. Flavonoids may serve as a catcher of superoxide anion and lipid superoxide radicals, and also may reduce the activity of superoxide free radicals. The objective of this research was to study the effects of solid to solvent ratio, ethanol concentration, and radiation time on the yield and Total Phenolic Compound (TPC) of extracts. Petai peels was firstly crushed without the addition of water. Petai peels was then used for extraction process in a domestic microwave. Solid to solvent ratio, ethanol concentration, and radiation time were varied. Following extraction, solvent was separated from the solid and then evaporated. The resulting extract powders were analyzed for yield and TPC. Antioxidant activity of extract was also studied as IC50. As result, petai peels extracted at solid to solvent ratio of 1:5, ethanol concentration of 96%, and extraction time of 150 second gave the highest TPC value of 41,43 g GAE /100 g petai peel extracts with IC50 of 364 µg/mL.Keywords: petai peels, domestic microwave, antioxidants, phenolics AbstrakPenelitian membuktikan bahwa petai (Parkia speciosa) mengandung antioksidan berupa polifenol dan flavonoid yang bisa menangkal radikal bebas dan mampu mencegah bahkan mengatasi beberapa macam penyakit serta dapat berfungsi sebagai penangkap anion superoksida dan lipid superoksida radikal, serta mengurangi aktivitas radikal bebas superoksida. Tujuan dari penelitian ini adalah untuk mempelajari pengaruh perbandingan padatan dan pelarut, konsentrasi etanol, dan waktu radiasi terhadap perolehan dan kadar senyawa fenolik atau Total Phenolic Compound (TPC) ekstrak kulit petai yang diperoleh dengan metode ekstraksi domestic microwave maceration. Mula-mula kulit petai diblender tanpa penambahan air. Proses ekstraksi kulit petai dengan pelarut etanol dilakukan dengan bantuan microwave pada variasi perbandingan padatan dan pelarut, konsentrasi etanol dan waktu radiasi. Setelah itu, padatan dipisahkan dengan pelarutnya. Pelarut diuapkan untuk mendapatkan ekstrak serbuk kulit petai. Ekstrak serbuk kulit petai dianalisis untuk mengetahui perolehan dan TPC. Aktivitas antioksidan ekstrak juga dianalisis dan dinyatakan dalam nilai Inhibisi 50% (IC50). Proses ekstraksi kulit petai yang menghasilkan TPC tertinggi adalah pada perbandingan padatan dan pelarut 1:5, konsentrasi etanol 96%, dan waktu radiasi 150 detik dengan nilai TPC yang diperoleh sebesar 41,43 g GAE (ekivalen asam galat) /100 g ekstrak kulit petai dan IC50 sebesar 364 µg/mL.Kata kunci: kulit petai, domestic microwave, antioksidan, fenolik

scholarly journals Optimization of Ultrasonic Extraction to Obtain Erinacine A and Polyphenols with Antioxidant Activity from the Fungal Biomass of Hericium erinaceus

Foods ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1889
Author(s):  
Mihai-Vlad Valu ◽  
Liliana Cristina Soare ◽  
Nicoleta Anca Sutan ◽  
Catalin Ducu ◽  
Sorin Moga ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Extraction Procedure ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Fungal Species ◽  
Extraction Yield ◽  
Ultrasonic Extraction ◽  
Hericium Erinaceus ◽  
High Antioxidant Activity ◽  
Erinacine A

Hericium erinaceus is a medicinal fungal species that produces the active biological metabolite erinacine A with strong antioxidant activity. The classical extraction techniques used to date to obtain metabolites from this fungal species require high consumption of resources and energy and, in the end, prove to be expensive and inefficient, especially on a biomedical scale. The aim of this research is based on the development of an ultrasonic extraction (UE) method for the identification and extraction of biological compounds with high antioxidant activity from the mycelia of H. erinaceus biomass developed through a solid cultivation process. The extraction process was optimized by varying parameters to determine the best extraction yield of metabolites involved in such antioxidant activity, using the response surface methodology (RSM). The physicochemical analyses were oriented towards the investigation of polyphenols, flavonoids, and the diterpenoid erinacine A. It is highlighted that there is a very good mutual connection between the concentration of polyphenols and flavonoids in the extracts studied and the diterpenoid erinacine A. Also, this study describes an efficient and qualitative extraction method for extracting natural antioxidants from the H. erinaceus mushroom, since toxic solvents were not used in the developed extraction procedure. This biomass can be used both as a food source and as a possible phytotherapeutic tool in the prevention or treatment of various neurodegenerative disorders that require drugs with strong antioxidant activity.

scholarly journals Promises and Challenges of Microalgal Antioxidant Production

Antioxidants ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 199 ◽  
Author(s):  
Clementina Sansone ◽  
Christophe Brunet
Keyword(s):  
Phenolic Compounds ◽  
Functional Food ◽  
Higher Plants ◽  
Health Benefits ◽  
Natural Antioxidants ◽  
Industrial Applications ◽  
Natural Antioxidant ◽  
Antioxidant Compounds ◽  
Food Ingredients

The exploration of natural antioxidants for nutraceuticals and pharmaceuticals industries has recently increased. This communication aims to grasp the relevance of microalgae in the panorama of natural antioxidant molecules supply to industrial applications as alternatives and/or complements to those typically used from higher plants. Microalgal richness in antioxidant compounds and scavenging ability compared to higher plants is discussed in the context of microalgal biodiversity. We mainly focus on families of powerful antioxidant compounds that have been scarcely investigated in microalgae, such as phenolic compounds, sterols, or vitamins, discussing the promise and challenges of microalgae as providers of health benefits, for instance, through their use as functional food ingredients.

Natural Antioxidants, Health Effects and Bioactive Properties of Wild Allium Species

2020 ◽  
Vol 26 (16) ◽  
pp. 1816-1837 ◽  
Author(s):  
Spyridon A. Petropoulos ◽  
Francesco Di Gioia ◽  
Nikos Polyzos ◽  
Nikos Tzortzakis
Keyword(s):  
Health Effects ◽  
Bioactive Compounds ◽  
Wild Species ◽  
Genetic Material ◽  
Natural Antioxidants ◽  
Antioxidant Compounds ◽  
Allium Species ◽  
Vast Number ◽  
Allium Ampeloprasum ◽  
Bioactive Properties

Background: There is an increasing interest from the pharmaceutical and food industry in natural antioxidant and bioactive compounds derived from plants as substitutes for synthetic compounds. The genus Allium is one of the largest genera, with more than 900 species, including important cultivated and wild species, having beneficial health effects. Objective: The present review aims to unravel the chemical composition of wild Allium species and their healthrelated effects, focusing on the main antioxidant compounds. For this purpose, a thorough study of the literature was carried out to compile reports related to health effects and the principal bioactive compounds. Considering the vast number of species, this review is divided into subsections where the most studied species are presented, namely Allium ampeloprasum, A. flavum, A. hookeri, A. jesdianum, A. neapolitanum, A. roseum, A. stipitatum, A. tricoccum, and A. ursinum, with an additional composite section for less studied species. Methods: The information presented in this review was obtained from worldwide accepted databases such as Scopus, ScienceDirect, PubMed, Google Scholar and Researchgate, using as keywords the respective names of the studied species (both common and Latin names) and the additional terms of “antioxidants” “health effects” and “bioactive properties”. Conclusion: The genus Allium includes several wild species, many of which are commonly used in traditional and folklore medicine while others are lesser known or are of regional interest. These species can be used as sources of natural bioactive compounds with remarkable health benefits. Several studies have reported these effects and confirmed the mechanisms of action in several cases, although more research is needed in this field. Moreover, considering that most of the studies refer to the results obtained from species collected in the wild under uncontrolled conditions, further research is needed to elucidate the effects of growing conditions on bioactive compounds and to promote the exploitation of this invaluable genetic material.

scholarly journals Cinnamomum zeylanicum: Morphology, Antioxidant Properties and Bioactive Compounds

2021 ◽  
Author(s):  
Asel Chandula Weerasekera ◽  
Kanchana Samarasinghe ◽  
Heethaka Krishantha Sameera de Zoysa ◽  
Thushara Chathuranga Bamunuarachchige ◽  
Viduranga Yashasvi Waisundara
Keyword(s):  
Essential Oils ◽  
Bioactive Compounds ◽  
Insulin Signaling ◽  
Positive Impact ◽  
Antioxidant Properties ◽  
Antioxidant Compounds ◽  
Cinnamomum Zeylanicum ◽  
Food Borne ◽  
Spoilage Bacteria ◽  
Progression Of Disease

Cinnamomum zeylanicum is one of the oldest spices used for culinary purposes in Asian countries. Its extracts have demonstrated a positive impact on controlling the progression of disease pathologies due to antioxidant, anti-inflammatory, antimicrobial, anticancer, anti-mutagenic, anti-tyrosinase and antidiabetic characteristics. C. zeylanicum also has its unique variations which makes it necessary to distinguish it from other species of cinnamon. Phenolic compounds such as cinnamaldehyde, eugenol, carvacrol, cinnamic acetate and thymol are the main compounds that can be found in essential oils of C. zeylanicum. However, cinnamaldehyde and eugenol act as the main bioactive antioxidant compounds found in C. zeylanicum because of their active functional groups in the structures. There are many examples of the use of C. zeylanicum extracts for medicinal purposes, specifically cinnamon metabolite proanthocyanidins which suppress inflammatory compounds and help pathways such as insulin signaling. Moreover, the bioactive compounds in essential oils of this plant are used against many pathogenic (including food-borne) and spoilage bacteria.

scholarly journals Valorization of Tomato Waste as a Source of Carotenoids

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 5062
Author(s):  
Sonia Trombino ◽  
Roberta Cassano ◽  
Debora Procopio ◽  
Maria Luisa Di Gioia ◽  
Eugenio Barone
Keyword(s):  
Bioactive Compounds ◽  
Fruits And Vegetables ◽  
Low Cost ◽  
Scientific Evidence ◽  
Value Added ◽  
Extraction Methods ◽  
Industrial Applications ◽  
Point Of View ◽  
Antioxidant Compounds ◽  
Tomato Waste

Fast-accumulating scientific evidence from many studies has revealed that fruits and vegetables are the main source of bioactive compounds; in most cases, wastes and byproducts generated by the food processing industry present similar or a higher content of antioxidant compounds. In recent years, the ever-growing amount of agricultural and food wastes has raised serious concerns from an environmental point of view. Therefore, there is an increasing interest in finding new ways for their processing toward safely upgrading these wastes for recovering high-value-added products with a sustainable approach. Among food waste, the abundance of bioactive compounds in byproducts derived from tomato suggests possibility of utilizing them as a low-cost source of antioxidants as functional ingredients. This contribution gives an overview of latest studies on the extraction methods of carotenoids from tomato waste, along with an evaluation of their antioxidant activity, as well as their industrial applications.

scholarly journals Study on the Effect and Mechanism of Impurity Aluminum on the Solvent Extraction of Rare Earth Elements (Nd, Pr, La) by P204-P350 in Chloride Solution

Minerals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 61
Author(s):  
Wenjie Zhang ◽  
Xian Xie ◽  
Xiong Tong ◽  
Yunpeng Du ◽  
Qiang Song ◽  
...  
Keyword(s):  
Rare Earth ◽  
Solvent Extraction ◽  
Rare Earth Elements ◽  
Organic Phase ◽  
Extraction Process ◽  
Industrial Applications ◽  
Separation And Purification ◽  
Aluminum Ion ◽  
Hydrochloric Acid Medium ◽  
Impurity Ion

Solvent extraction is the most widely used method for separation and purification of rare earth elements, and organic extractants such as di(2-ethylhexyl) phosphoric acid (P204) and di(1-methyl-heptyl) methyl phosphonate (P350) are most commonly used for industrial applications. However, the presence of impurity ions in the feed liquid during extraction can easily emulsify the extractant and affect the quality of rare earth products. Aluminum ion is the most common impurity ion in the feed liquid, and it is an important cause of emulsification of the extractant. In this study, the influence of aluminum ion was investigated on the extraction of light rare earth elements by the P204-P350 system in hydrochloric acid medium. The results show that Al3+ competes with light rare earths in the extraction process, reducing the overall extraction rate. In addition, the Al3+ stripping rate is low and there is continuous accumulation of Al3+ in the organic phase during the stripping process, affecting the extraction efficiency and even causing emulsification. The slope method and infrared detection were utilized to explore the formation of an extraction compound of Al3+ and the extractant P204-P350 that entered the organic phase as AlCl[(HA)2]2P350(o).

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