scholarly journals Effects of Food Processing on In Vivo Antioxidant and Hepatoprotective Properties of Green Tea Extracts

Antioxidants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 572 ◽  
Author(s):  
Xiao-Yu Xu ◽  
Jie Zheng ◽  
Jin-Ming Meng ◽  
Ren-You Gan ◽  
Qian-Qian Mao ◽  
...  
Keyword(s):  
Green Tea ◽  
Food Processing ◽  
Antioxidant Activities ◽  
Ultrasound Treatment ◽  
Positive Effects ◽  
In Vivo Experiments ◽  
Study Results ◽  
Negative Effect

Food processing can affect the nutrition and safety of foods. A previous study showed that tannase and ultrasound treatment could significantly increase the antioxidant activities of green tea extracts according to in vitro evaluation methods. Since the results from in vitro and in vivo experiments may be inconsistent, the in vivo antioxidant activities of the extracts were studied using a mouse model of alcohol-induced acute liver injury in this study. Results showed that all the extracts decreased the levels of aspartate transaminase and alanine aminotransferase in serum, reduced the levels of malondialdehyde and triacylglycerol in the liver, and increased the levels of catalase and glutathione in the liver, which can alleviate hepatic oxidative injury. In addition, the differences between treated and original extracts were not significant in vivo. In some cases, the food processing can have a negative effect on in vivo antioxidant activities. That is, although tannase and ultrasound treatment can significantly increase the antioxidant activities of green tea extracts in vitro, it cannot improve the in vivo antioxidant activities, which indicates that some food processing might not always have positive effects on products for human benefits.

scholarly journals A Simple and a Reliable Method to Quantify Antioxidant Activity In Vivo

Antioxidants ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 142 ◽  
Author(s):  
María Pilar de Torre ◽  
Rita Yolanda Cavero ◽  
María Isabel Calvo ◽  
José Luis Vizmanos
Keyword(s):  
Antioxidant Activity ◽  
Green Tea ◽  
Reliable Method ◽  
Positive Control ◽  
Negative Control ◽  
In Vivo Model ◽  
In Vivo Experiments ◽  
Age Related

The characterization of compounds with antioxidant activity is of great interest due to their ability to reduce reactive oxygen species production and, therefore, prevent some age-related diseases. Its antioxidant capacity can be analyzed by different methods both in vitro and in vivo. Caenorhabditis elegans is an in vivo model widely used in ageing research. Until now, available tests analyze functional effects in the worms, so the antioxidant activity of the compound is indirectly monitored. We have developed a simple and a reliable method to quantify internal antioxidant activity in vivo. To validate this method, we analyzed an aqueous green tea extract and two other compounds with a well-known antioxidant activity and without this activity. The results obtained (EC50 green tea = 21.76 ± 1.28 µg/mL; EC50 positive control = 8.50 ± 0.33 µg/mL; negative control EC50 > 500 µg/mL) can help in the design of further in vivo experiments. Thus, our method can be used as a previous screening capable of reducing the gap between in vitro and in vivo assays.

scholarly journals Healthy drinks made from okra and green tea extract for reducing blood cholesterol

Food Research ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 468-473
Author(s):  
Melanie Cornelia ◽  
M. Anggraini
Keyword(s):  
Antioxidant Activity ◽  
Green Tea ◽  
Antioxidant Activities ◽  
Green Tea Extract ◽  
Blood Cholesterol ◽  
Activity Data ◽  
Cholesterol Levels ◽  
Tea Extract

Okra (Abelmoschus esculentus L.) seeds and green tea (Camellia sinensis) have been known have many beneficial functions for human’s health, because of the high antioxidant contents and anti-cholesterol activities that can prevent cardiovascular disease. This research is aimed to make the formulation of healthy drink from okra seed juice with the addition of green tea extract. Green tea used was selected from green tea that has the best antioxidant activity from ten samples of green tea in the market. The best antioxidant activity data was found in Jawa tea extract with IC50 85.28±0.21 µg/mL which was formulated with the extract of okra seeds, made in the ratio of 1: 4. Selected healthy drinks were tested for physical characteristics, antioxidant activities, and sensory tests, and have antioxidant activity IC50 222.16±1.38 µg/mL. Further research was to analyze the potential of drinks in reducing cholesterol in vitro and in vivo ways. In vitro, 500 ppm drinks were able to inhibit cholesterol up to 47.55±0.76% and in vivo, there was a significant decrease in cholesterol levels after drink for 21 days with cholesterol reduction to 35.50±2.37%, triglycerides decrease 19.39±3.10%, LDL decrease 34.76±2.62%, and an increase of HDL to 94.74±16.53%.

Anti-atherosclerotic effects of fruit bioactive compounds: A review of current scientific evidence

2012 ◽  
Vol 92 (3) ◽  
pp. 407-419 ◽  
Author(s):  
Surangi H. Thilakarathna ◽  
H. P. Vasantha Rupasinghe
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Scientific Evidence ◽  
Experimental Models ◽  
Lipid Lowering ◽  
Experimental Conditions ◽  
Beneficial Effects ◽  
Positive Effects

Thilakarathna, S. H. and Rupasinghe, H. P. V. 2012. Anti-atherosclerotic effects of fruit bioactive compounds: A review of current scientific evidence. Can. J. Plant Sci. 92: 407–419. Atherosclerosis is a condition which leads to a cascade of processes involved in thickening of arterial walls as a result of fatty deposition, which can increase the risk of cardiovascular diseases. Among numerous remedies, the consumption of fruits is believed to have beneficial effects on atherosclerosis development. Various bioactive compounds are present in fruits and they have been found to be responsible for exerting these beneficial effects. Fruit flavonoids and certain terpenoids are among the most efficacious fruit bioactive compounds that have shown positive effects on different in vitro as well as in vivo research models of atherosclerosis. The mechanisms of actions of these compounds vary from exerting antioxidant activities to anti-atherogenic and lipid lowering activities, based on different experimental models. This review article briefly explains how some of the fruit bioactive compounds have affected atherosclerosis under experimental conditions.

scholarly journals Study on the antioxidant activity of Portulaca oleracea L. in vitro by HPLCESR and in vivo on transgenic Drosophila melanogaster model

2015 ◽  
Vol 18 (4) ◽  
pp. 32-41
Author(s):  
Trang Thi Xuan Dai ◽  
Thao Thi Phuong Truong ◽  
Kaeko Kamei
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Activities ◽  
Portulaca Oleracea ◽  
In Vivo Experiments ◽  
Esr Spin Trapping ◽  
Before And After ◽  
High Antioxidant Activity ◽  
Ground Powder

A study in vitro on the antioxidant activity of Portulaca oleracea L. was carried out by HPLC-ESR Spin-trapping System. HPLCESR analysis is performed on monitoring ESR signal intensity of radicals adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO/O2). The ESR signal which is recorded from the Portulaca oleracea L. extracts in aqueous buffer by HPLC-ESR system showed that the high antioxidant activity of the extracts reduce the concentration of DMPO/O2 signal to 80 % and the absorbance of reactive oxygen species from 0.08 to 0.06. The ground powder and the extract of Portulaca oleracea were in vivo performed on GMRGAL4/ UAS-hDuox2 flies containing hDuox2 protein which induced high oxidative stress and expressed rough-eye phenotype. Antioxidant activities of Portulaca oleracea were evaluated by comparing the rough-eye area before and after the experiment. At the concentration of 20 %, the ground powder and the extracts induced antioxidant activities to 81.72 % and 87.33 %, respectively. The result showed that both the ground powder and the extracts had antioxidant activities which reduced symptoms of rough-eye phenotypes. In conclusion, the in vitro and in vivo experiments indicated that both ground power and aqueous extract of leaves of Portulaca oleracea possess effective antioxidative abilities.

scholarly journals Exercise-Induced Irisin, the Fat Browning Myokine, as a Potential Anticancer Agent

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
George-Emmanuel Maalouf ◽  
Diala El Khoury
Keyword(s):  
Insulin Resistance ◽  
Anticancer Agent ◽  
Metabolic Diseases ◽  
Fat Metabolism ◽  
Positive Effects ◽  
Different Types ◽  
Negative Effect ◽  
Exercise Induced

Irisin is a recently discovered myokine that plays an important role in fat metabolism through the browning of white adipose tissue. This myokine is usually secreted after exercise by improving energy balance and has shown great potential as a possible treatment for some metabolic diseases such as obesity, insulin resistance, and inflammation. Obesity has been linked to a higher incidence of some cancers. Furthermore, some studies have shown irisin to have direct positive effects on different types of cancers. Although it is hard to relay conclusions from in vitro to in vivo studies, the majority of the available data favor irisin as a potential substance for cancer regression through reducing proinflammatory markers linked to obesity. However, some controversies remain on the exact benefits of irisin on cancer with some studies showing no or even a negative effect of irisin on cancer. This review summarizes these 2 differing viewpoints and synthesizes them to form a clearer picture of exercise-induced irisin’s effects on cancer.

Effects of nitrogen fertilisation and two growing sites on biomass production and lignan content of linseed ( Linum usitatissimum L.): Second year

2007 ◽  
Vol 55 (2) ◽  
pp. 173-181 ◽  
Author(s):  
R. Zimmermann ◽  
U. Bauermann ◽  
C. Spedding
Keyword(s):  
Food Processing ◽  
Genetic Material ◽  
Human Colon ◽  
Raw Material ◽  
Positive Effects ◽  
Linum Usitatissimum L ◽  
Second Year ◽  
First Time

Mammary and prostatic carcinomas are the most frequently diagnosed in the population of Western Countries. Recent in vitro and in vivo studies have demonstrated the positive effects of mammalian lignans in retarding the development of these carcinomas. Mammalian lignans, such as enterolactone and enterodiol, originate in the human colon from precursors provided through food consumption. Linseed is currently one of the best sources of secoisolariciresinol (seco) and matairesinol (mata), which have been identified as the major precursors of enterolactone and enterodiol. Even though linseed contains outstanding amounts of these substances, knowledge about the ecophysiology of the active agents is very scarce. Therefore, it seemed necessary to investigate the variability in the formation and accumulation of lignans in linseed in order to provide stable, high-quality plant raw material for the food processing industry. The following paper presents the second growing year of a trial series showing the effects of two locations and enhanced N fertilisation at one site on 12 linseed varieties. Six of the varieties were selected from the previous years and six varieties were included for the first time. It could be shown that the variability of both lignans caused by the factor “cultivar” was much greater than either “location” or “fertiliser intensity”. The ranking of the cultivars was very consistent, however, indicating that the genotypic share of the expression was greater than the phenotypic share. The findings confirm the results of the previous year. It was possible to identify superior genetic material based on two growing periods.

In vitro and in vivo antioxidant activities of the leaves of Chrysophyllum albidum

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
AH Adebayo ◽  
AO Abolaji ◽  
OO Ayepola ◽  
TB Olorunfemi ◽  
OS Taiwo
Keyword(s):  
Antioxidant Activities

In vitro antioxidant activities of Bauhinia strychnifolia extracts: Comparison with green tea extracts

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
A Itharat ◽  
S Sayompark ◽  
P Hansakul ◽  
B Dechayont
Keyword(s):  
Green Tea ◽  
Antioxidant Activities
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