scholarly journals A Bibliometric Review of the Keap1/Nrf2 Pathway and its Related Antioxidant Compounds

Antioxidants ◽  
2019 ◽  
Vol 8 (9) ◽  
pp. 353 ◽  
Author(s):  
Ana Paunkov ◽  
Dionysios V. Chartoumpekis ◽  
Panos G. Ziros ◽  
Gerasimos P. Sykiotis
Keyword(s):  
Web Of Science ◽  
Research Field ◽  
Antioxidant Compounds ◽  
Nrf2 Pathway ◽  
The Past ◽  
Reverse Pattern ◽  
The Usa ◽  
Bibliometric Review ◽  
The Subject ◽  
Active Research

Nrf2 is a master transcriptional regulator of antioxidant and cytoprotective pathways. Currently in its third decade, research on Nrf2 has expanded to encompass not only basic but also clinical studies. In the present bibliometric review, we employed the VOSviewer tool to describe the existing Nrf2 literature landscape. As of July 2019, 11,931 papers on Nrf2 were listed in the “Web of Science” database, with more than 1000 new papers published each year. As expected, terms related to oxidative stress and antioxidant molecules occur very often in the Nrf2 literature throughout the years. Interestingly, there is also a gradual increase in the occurrence of terms related to diseases or to natural compounds, the most prominent being sulforaphane, curcumin, and resveratrol that modulate the Nrf2 pathway. Going beyond molecular biology/biochemistry and related fields, Nrf2 research has begun to spread into more clinical areas like endocrinology/metabolism, cardiology, and nephrology, likely reflecting an increased interest in clinical applications of Nrf2 pathway activators. China has become the most prolific producer of Nrf2 papers the last five years followed by the USA and Japan, a reverse pattern compared to the past. In conclusion, Nrf2 is the subject of a globally active research field that keeps growing and extends from bench to bedside.

scholarly journals A Bibliometric Review of Publications on Oxidative Stress and Chemobrain: 1990–2019

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 439
Author(s):  
Taylor McElroy ◽  
Antiño R. Allen
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Central Nervous System ◽  
Web Of Science ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
The Usa ◽  
Bibliometric Review ◽  
The Subject ◽  
The Web

Oxidative stress is considered one of the possible mechanisms behind chemobrain or the cognitive dysfunction persistent after chemotherapy treatment. Breast cancer patients have reported chemobrain symptoms since the 1990s. In this present bibliometric review, we employed the VOSviewer tool to describe the existing landscape on literature concerning oxidative stress, breast cancer chemotherapies, and chemobrain. As of 2019, 8799 papers were listed in the Web of Science database, with more than 900 papers published each year. As expected, terms relating to oxidative stress, mitochondria, breast cancer, and antioxidants have occurred very often in the literature throughout the years. In recent years, there has been an increase in the occurrence of terms related to nanomedicine. Only within the last decade do the keywords ‘brain’, ‘blood-brain barrier’, and ‘central nervous system’ appear, reflecting an increased interest in chemobrain. China has become the most prolific producer of oxidative stress and chemotherapy related papers in the last decade followed by the USA and India. In conclusion, the subject of oxidative stress as a mechanism behind chemotherapies’ toxicities is an active area of research.

scholarly journals Top-100 Most Cited Publications Concerning Network Pharmacology: A Bibliometric Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Cuncun Lu ◽  
Zhitong Bing ◽  
Zhijiang Bi ◽  
Ming Liu ◽  
Tingting Lu ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Web Of Science ◽  
Drug Research ◽  
Research Field ◽  
Current Status ◽  
Network Pharmacology ◽  
The Past ◽  
The Usa ◽  
Number Of Citations

Background. Network pharmacology (NP) has become an increasingly important focus in the drug research field over the past decade. However, no study to date has mapped the current status of NP. Therefore, we performed a bibliometric study to evaluate the top 100 cited papers on NP. Methods. We searched the Web of Science Core Collection from its inception to February 25, 2019, using the terms “network pharmacology” and “systems pharmacology.” Key data, including title, publication year, number of citations, authors, countries/regions, organizations, and journals, were retrieved and analyzed using Excel 2016 and VOSviewer 1.6.10. Results. The total number of citations for the 100 cited papers ranged from 21 to 1,238, published in 53 journals, from 2005 to 2017. The top three journals with the most publications on NP were Clinical Pharmacology & Therapeutics (n = 8, IF2017 = 6.544), Journal of Ethnopharmacology (n = 8, IF2017 = 3.115), and PLoS One (n = 7, IF2017 = 2.766). Most published articles were from the USA (n = 41) and China (n = 35). The most active author was Wang Yonghua from the Northwest A&F University, and of the 100 publications, 14 listing his name. The most frequently used substantive terms included “drug discovery,” “traditional Chinese medicine (TCM),” “in-vitro,” “cancer,” and “cardiovascular disease.” Conclusions. The USA and China made the greatest contribution to NP research. The current NP research mainly focused on NP methods (including experimental validation) and using them to explore the molecular mechanisms of TCM for some critical diseases such as cardiovascular diseases and cancers. Furthermore, we believe some guidelines should be developed to regulate NP studies.

Ergonomics 4.0: A bibliometric review of human Factors research in Industrial revolution 4.0 (IR 4.0)

Work ◽  
2021 ◽  
pp. 1-14
Author(s):  
Mohammad Babamiri ◽  
Rashid Heidarimoghadam ◽  
Fakhrodin Ghasemi ◽  
Leili Tapak ◽  
Alireza Mortezapour
Keyword(s):  
Human Factors ◽  
Bibliometric Analysis ◽  
Industry 4.0 ◽  
Industrial Revolution ◽  
Web Of Science ◽  
Research Field ◽  
Related Field ◽  
Fourth Industrial Revolution ◽  
The Usa ◽  
Bibliometric Review

BACKGROUND: The scientometric study is a visualization method used to collect big data from databases, to explore the relationships between citing and co-cited documents and then visualize the results. Unlike the new term Ergonomics 4.0, bibliometric analysis has been studied in various related fields of Ergonomics. OBJECTIVE: The aim of this study was to create a bibliometric analysis in related field of Ergonomics and Fourth Industrial Revolution. This analysis can shed light on the new developed research field in both sides of the present study, occupational ergonomics and industry 4.0. METHODS: After selecting related keywords, Advance search was done in Scopus and Web of Science. Bibliometric results were presented by these databases’ analyzer and by exported data to VOS viewer software. No time or language restriction was applied. RESULTS: Retrieved Articles were 104 and 285 for Web of Science and Scopus respectively. The frequent co-occurrences for keywords were seen between “industry 4.0” and “Human Factors”. The USA and Germany were also the most productive countries in this field. Well-known Ergonomics journals had low participation in the Evolution of Ergonomics and Fourth Industrial Revolution topics. CONCLUSION: Due to more participation of industry 4.0-related researchers in this topic, it is recommended that ergonomists from around the world, and especially Eastern countries, attempt to conduct research in this field. Furthermore, devoting some forth-coming special issues in this field is recommended to top ergonomics journals.

scholarly journals A Theoretical Framework on the Determinants of Food Purchasing Behavior of the Elderly: A Bibliometric Review with Scientific Mapping in Web of Science

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 688
Author(s):  
Khaled Alhammadi ◽  
Luna Santos-Roldán ◽  
Luis Javier Cabeza-Ramírez
Keyword(s):  
Elderly Population ◽  
Web Of Science ◽  
The Elderly ◽  
Purchasing Behavior ◽  
Food Purchasing ◽  
The Past ◽  
Bibliometric Review ◽  
Food Market ◽  
The Common ◽  
Elderly Consumers

The past few years have seen significant demographic changes in most regions, including an increased elderly population. Subsequently, elderly citizens comprise an important market segment of consumers, with the food industry one of the most affected areas in this context. However, food market managers previously believed that elderly consumers’ needs were stereotyped in nature. The lack of focus on this sector, therefore, left elderly consumers as an untapped market, without realizing the financial independence of this segment regarding their nutrition. This research will attempt to provide the key determinant factors on elderly consumers’ behavior related to food. For that purpose, a complete literature review of more than 123 papers regarding these concepts has been carried out. Once analyzed, we highlight the common insights to give clear guidance for supermarket managers and food manufacturers to have a better knowledge of the reasons behind elderly people’s food acquisitions.

scholarly journals Energy Storage Ceramics: A Bibliometric Review of Literature

Materials ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3605
Author(s):  
Haiyan Hu ◽  
Aiping Liu ◽  
Yuehua Wan ◽  
Yuan Jing
Keyword(s):  
Energy Storage ◽  
Materials Science ◽  
Research Field ◽  
Highly Cited Papers ◽  
Research Areas ◽  
Productive Author ◽  
The Usa ◽  
Bibliometric Review ◽  
Leading Position ◽  
Highly Cited

Energy storage ceramics is among the most discussed topics in the field of energy research. A bibliometric analysis was carried out to evaluate energy storage ceramic publications between 2000 and 2020, based on the Web of Science (WOS) databases. This paper presents a detailed overview of energy storage ceramics research from aspects of document types, paper citations, h-indices, publish time, publications, institutions, countries/regions, research areas, highly cited papers, and keywords. A total of 3177 publications were identified after retrieval in WOS. The results show that China takes the leading position in this research field, followed by the USA and India. Xi An Jiao Tong Univ has the most publications, with the highest h-index. J.W. Zhai is the most productive author in energy storage ceramics research. Ceramics International, Journal of Materials Science-Materials in Electronics, and the Journal of Alloys and Compounds are the most productive journals in this field, and materials science—multidisciplinary is the most frequently used subject category. Keywords, highly cited papers, and the analysis of popular papers indicate that, in recent years, lead-free ceramics are prevalent, and researchers focus on fields such as the microstructure, thin films, and phase transition of ceramics.

scholarly journals Recent Advances in bis-Chalcone-Based Photoinitiators of Polymerization: From Mechanistic Investigations to Applications

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3192
Author(s):  
Nicolas Giacoletto ◽  
Frédéric Dumur
Keyword(s):  
Free Radical ◽  
Radical Polymerization ◽  
Cationic Polymerization ◽  
Free Radical Polymerization ◽  
Research Field ◽  
4D Printing ◽  
Unique Structure ◽  
The Past ◽  
Mechanistic Investigations ◽  
Active Research

Over the past several decades, photopolymerization has become an active research field, and the ongoing efforts to develop new photoinitiating systems are supported by the different applications in which this polymerization technique is involved—including dentistry, 3D and 4D printing, adhesives, and laser writing. In the search for new structures, bis-chalcones that combine two chalcones’ moieties within a unique structure were determined as being promising photosensitizers to initiate both the free-radical polymerization of acrylates and the cationic polymerization of epoxides. In this review, an overview of the different bis-chalcones reported to date is provided. Parallel to the mechanistic investigations aiming at elucidating the polymerization mechanisms, bis-chalcones-based photoinitiating systems were used for different applications, which are detailed in this review.

scholarly journals ELIXIR and Toxicology: a community in development

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 1129
Author(s):  
Marvin Martens ◽  
Rob Stierum ◽  
Emma L. Schymanski ◽  
Chris T. Evelo ◽  
Reza Aalizadeh ◽  
...  
Keyword(s):  
Life Science ◽  
High Gain ◽  
Research Field ◽  
Predictive Toxicology ◽  
Chemical Risk Assessment ◽  
The Past ◽  
Government Involvement ◽  
Active Research ◽  
New Community ◽  
The Eu

Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.

scholarly journals Internet and People with Intellectual Disability: A Bibliometric Analysis

2020 ◽  
Vol 12 (23) ◽  
pp. 10051
Author(s):  
Santiago Mengual-Andrés ◽  
Esther Chiner ◽  
Marcos Gómez-Puerta
Keyword(s):  
Intellectual Disability ◽  
Scientific Collaboration ◽  
Systematic Approach ◽  
Web Of Science ◽  
Research Field ◽  
Journal Citation Reports ◽  
The United Kingdom ◽  
The Subject ◽  
People With Intellectual Disabilities ◽  
Use Of The Internet

The use of the Internet by people with intellectual disabilities is an area of study that has captured the interest of scientists in recent years. The studies have focused on analyzing specific aspects such as usability, the activities carried out online, and Internet benefits and risks, among others. The reviews published on this matter have been of a narrative or systematic approach. The present study aimed to examine the academic output in the field of Internet and people with intellectual disability from a bibliometric perspective. A sample of 95 documents related to the topic was retrieved from the core collection of Web of Science (WoS) and analyzed using the bibliometrix R-Tool. Findings show a recent increase in publications related to the subject and confirm Price’s and Bradford’s laws. The most relevant sources on the topic are devoted to the research field of intellectual disability and Spain, the United Kingdom and Sweden stand out as the most productive countries. Studies tend to be published by co-authorship in journals indexed at the Journal Citation Reports (JCR) achieving a global impact. However, international scientific collaboration is still scarce. Further bibliometric analyses are recommended to build a complete panorama of the research field.

scholarly journals Global palliative care research (2002-2020): bibliometric review and mapping analysis

2021 ◽  
pp. bmjspcare-2021-002982
Author(s):  
Hammoda Abu-Odah ◽  
Alex Molassiotis ◽  
Justina Yat Wa Liu
Keyword(s):  
Palliative Care ◽  
Low Income ◽  
Research Field ◽  
Cancer Prognosis ◽  
Inclusion Criteria ◽  
Middle Income ◽  
Global Trends ◽  
Related Research ◽  
The Usa ◽  
Bibliometric Review

Background and objectiveDespite the important benefits of a bibliometric approach on mapping a research field, relatively little efforts have previously been conducted to map and analyse the global trends of palliative care (PC)-related research. This bibliometric review aimed to provide an overall picture and systematic mapping of the state of research trends within the field of PC internationally.MethodsScopus and Web of Science databases were searched to retrieve original articles focusing on PC between 2002 and 2020. Searching was conducted on 5 May 2020, and was updated on 6 May 2021. All retrieved articles were assessed by title and abstract, and the bibliometric metadata of those that met the inclusion criteria were downloaded for analysis. The results were analysed by VOSviewer and Gephi software.ResultsA total of 19,199 articles met the inclusion criteria. Significant growth of the number of published articles was reported by around five-fold from 2002 to 2020. The USA and UK were the most productive countries in terms of the number of papers published and citations. Weak collaborations were observed between low-income or middle-income countries and high-income countries. Cancer-related PC research was the most common focus. Seven clusters of research were identified and included heart failure and cancer prognosis, nursing home, pain and symptoms management, PC knowledge and attitudes, quality improvement of services, PC ethics, and the ongoing assessment of PC services.ConclusionsThere is a need to expand PC-related research to non-cancer diseases. More international research and cross-institutional cooperation is required to address more global PC issues and benefit from wider sharing of expertees, potentially leading to higher quality or more impactful studies. Setting up research agendas and priorities from funding bodies and institutions may also enhance cooperation among researchers.

scholarly journals Big Data in Education. A Bibliometric Review

2019 ◽  
Vol 8 (8) ◽  
pp. 223 ◽  
Author(s):  
José-Antonio Marín-Marín ◽  
Jesús López-Belmonte ◽  
Juan-Miguel Fernández-Campoy ◽  
José-María Romero-Rodríguez
Keyword(s):  
Big Data ◽  
Learning Process ◽  
Subject Matter ◽  
Web Of Science ◽  
Scientific Production ◽  
Bibliometric Study ◽  
Future Research ◽  
Bibliometric Review ◽  
The Subject ◽  
Teaching Learning

The handling of a large amount of data to analyze certain behaviors is reaching a great popularity in the decade 2010–2020. This phenomenon has been called Big Data. In the field of education, the analysis of this large amount of data, generated to a greater extent by students, has begun to be introduced in order to improve the teaching–learning process. In this paper, it was proposed as an objective to analyze the scientific production on Big Data in education in the databases Web of Science (WOS), Scopus, ERIC, and PsycINFO. A bibliometric study was carried out on a sample of 1491 scientific documents. Among the results, the increase in publications in 2017 and the configuration of certain journals, countries and authors as references in the subject matter stand out. Finally, potential explanations for the study findings and suggestions for future research are discussed.

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