scholarly journals Protective Effect of Aqueous Extract from the Leaves of Justicia tranquebariesis against Thioacetamide-Induced Oxidative Stress and Hepatic Fibrosis in Rats

Antioxidants ◽  
2018 ◽  
Vol 7 (7) ◽  
pp. 78 ◽  
Author(s):  
Kumeshini Sukalingam ◽  
Kumar Ganesan ◽  
Baojun Xu
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Hepatic Fibrosis ◽  
Aqueous Extract

scholarly journals Aqueous Extract of Cocoa Phenolic Compounds Protects Differentiated Neuroblastoma SH-SY5Y Cells from Oxidative Stress

Biomolecules ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1266
Author(s):  
Noelia Carballeda Sangiao ◽  
Susana Chamorro ◽  
Sonia de Pascual-Teresa ◽  
Luis Goya
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Phenolic Compounds ◽  
Protective Effect ◽  
Aqueous Extract ◽  
Antioxidant Properties ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Human Neuroblastoma ◽  
Antioxidant Defense Enzymes

Cocoa is a rich source of polyphenols, especially flavanols and procyanidin oligomers, with antioxidant properties, providing protection against oxidation and nitration. Cocoa phenolic compounds are usually extracted with methanol/ethanol solvents in order to obtain most of their bioactive compounds; however, aqueous extraction seems more representative of the physiological conditions. In this study, an aqueous extract of cocoa powder has been prepared and chemically characterized, and its potential protective effect against chemically-induced oxidative stress has been tested in differentiated human neuroblastoma SH-SY5Y cells. Neuronal-like cultured cells were pretreated with realistic concentrations of cocoa extract and its major monomeric flavanol component, epicatechin, and then submitted to oxidative stress induced by a potent pro-oxidant. After one hour, production of reactive oxygen species was evaluated by two different methods, flow cytometry and in situ fluorescence by a microplate reader. Simultaneously, reduced glutathione and antioxidant defense enzymes glutathione peroxidase and glutathione reductase were determined and the results used for a comparative analysis of both ROS (reactive oxygen species) methods and to test the chemo-protective effect of the bioactive products on neuronal-like cells. The results of this approach, never tested before, validate both analysis of ROS and indicate that concentrations of an aqueous extract of cocoa phenolics and epicatechin within a physiological range confer a significant protection against oxidative insult to neuronal-like cells in culture.

scholarly journals Protective effect of <em>Cyclolepis genistoides</em> aqueous extract against cellular oxidative stress

2020 ◽  
Author(s):  
Gabriela Salvador ◽  
Natalia Alza ◽  
Oriana Benzi Juncos ◽  
Ana Murray
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Aqueous Extract

Protective effect of Allium sativum (garlic) aqueous extract against lead-induced oxidative stress in the rat brain, liver, and kidney

2016 ◽  
Vol 24 (2) ◽  
pp. 1544-1552 ◽  
Author(s):  
V. Manoj Kumar ◽  
A. K. Henley ◽  
C. J. Nelson ◽  
O. Indumati ◽  
Y. Prabhakara Rao ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Rat Brain ◽  
Aqueous Extract ◽  
Allium Sativum ◽  
Liver And Kidney

scholarly journals The protective effect of the aqueous extract of parsley (Petroselinum sativum ) seeds on experimentally – induced oxidative stress in rats

2021 ◽  
Vol 25 (1) ◽  
pp. 154-172
Author(s):  
K. K. Khudiar ◽  
B. N. Abdullah ◽  
K. A. Al-Mzaien
Keyword(s):  
Oxidative Stress ◽  
Drinking Water ◽  
Protective Effect ◽  
Aqueous Extract ◽  
Plasma Cholesterol ◽  
Male Rats ◽  
Cholesterol Concentration ◽  
Control Group ◽  
Albino Rats ◽  
Group I

In this study, the potential protective effect of aqueous extract of parsley (Petroselinum sativum) seeds against hydrogen peroxide (H2O2) – induced oxidative stress in male rats was assessed. Three groups of male albino rats were randomly divided (n=7) and were handled for twenty-eight days as follows: rats in group I served as control; animals in group || were provided with drinking water containing 0.5% H2O2 and those in group III received orally 8 mg/100 gm B.W. of aqueous extract of parsley seeds plus 0.5% H2O2 in drinking water. After four weeks experimental period, a significant increase in lipid peroxidation products (MDA), and decrease in glutathione (GSH) concentrations were observed in plasma, kidney, liver and heart tissues of H2O2 treated animals as compared with the control group. These biomarkers (GSH and MDA) are interrelated and indicate the occurrence of oxidative stress. Plasma total cholesterol (TC) concentration was significantly increased in H2O2 treated rats. By administration of aqueous extract of parsley along with H2O2, plasma and tissue GSH levels were significantly increased while the elevation in MDA level was diminished in plasma and different tissues examined. A decrease in plasma cholesterol concentration was recorded in H2O2 and parsley treated group as compared with the control one and H2O2 treated groups. These results indicate that aqueous extract of parsley have hypocholesterolemic and antioxidant effect.

scholarly journals Protective effect of nutmeg aqueous extract against experimentally-induced hepatotoxicity and oxidative stress in rats

2013 ◽  
Vol 4 (4) ◽  
pp. 216 ◽  
Author(s):  
MohammedAbdul Kareem ◽  
AlthafHussain Shaik ◽  
EMaruthi Prasad ◽  
LakshmiDevi Kodidhela ◽  
SaayiKrushna Gadhamsetty
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Aqueous Extract ◽  
And Oxidative Stress ◽  
Experimentally Induced

scholarly journals Protective effect of Melissa officinalis aqueous extract against Mn-induced oxidative stress in chronically exposed mice

2012 ◽  
Vol 87 (1) ◽  
pp. 74-79 ◽  
Author(s):  
Eduarda N. Martins ◽  
Naira T.C. Pessano ◽  
Luiza Leal ◽  
Daniel H. Roos ◽  
Vanderlei Folmer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Aqueous Extract ◽  
Melissa Officinalis

Protective effect of aqueous extract of Allium sativum against zearalenone toxicity mediated by oxidative stress

2012 ◽  
Vol 64 (7-8) ◽  
pp. 689-695 ◽  
Author(s):  
S. Abid-Essefi ◽  
C. Zaied ◽  
C. Bouaziz ◽  
I. Ben Salem ◽  
R. Kaderi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Aqueous Extract ◽  
Allium Sativum

Attenuation of oxidative stress in hepatic and pancreatic tissues of STZ-induced diabetic rats treated with aqueous extract of Vochysia rufa

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
NM De Gouveia ◽  
IB Moraes ◽  
RMF Sousa ◽  
MB Neto ◽  
AV Mundim ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Aqueous Extract ◽  
Diabetic Rats

Antioxidant Activity and Protective Effect against Oxidative Stress on Hippocampal HT22 Cells of Tea Seed Oil

2018 ◽  
Vol 24 (1) ◽  
pp. 53-59
Author(s):  
Jong Min Kim ◽  
Seon Kyeong Park ◽  
Jin Yong Kang ◽  
Seong-kyeong Bae ◽  
Ga-Hee Jeong ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Protective Effect ◽  
Seed Oil ◽  
Ht22 Cells ◽  
Tea Seed Oil
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