scholarly journals Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 620
Author(s):  
Dalia M. Kopustinskiene ◽  
Jurga Bernatoniene
Keyword(s):  
Alternative Medicine ◽  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Polyphenolic Compounds ◽  
Schisandra Chinensis ◽  
Aging Effects ◽  
Fruit Extract ◽  
Active Constituents ◽  
Pathological Conditions ◽  
Antioxidant Effects

Schisandra chinensis Turcz. (Baill.) fruits, their extracts, and bioactive compounds are used in alternative medicine as adaptogens and ergogens protecting against numerous neurological, cardiovascular, gastrointestinal, liver, and skin disorders. S. chinensis fruit extracts and their active compounds are potent antioxidants and mitoprotectors exerting anti-inflammatory, antiviral, anticancer, and anti-aging effects. S. chinensis polyphenolic compounds—flavonoids, phenolic acids and the major constituents dibenzocyclooctadiene lignans are responsible for the S. chinensis antioxidant activities. This review will focus on the direct and indirect antioxidant effects of S. chinensis fruit extract and its bioactive compounds in the cells during normal and pathological conditions.

scholarly journals Comparison of Bioactive Compounds and Antioxidant Activities of Maclura tricuspidata Fruit Extracts at Different Maturity Stages

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 567 ◽  
Author(s):  
Dae-Woon Kim ◽  
Won-Jae Lee ◽  
Yoseph Asmelash Gebru ◽  
Han-Seok Choi ◽  
Soo-Hwan Yeo ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Folk Medicine ◽  
Antioxidant Properties ◽  
Polyphenolic Compounds ◽  
Total Carotenoids ◽  
Food Material ◽  
Maturity Stages ◽  
Flight Mass Spectrometry ◽  
First Time

Abstract: Maclura tricuspidata fruit contains various bioactive compounds and has traditionally been used in folk medicine and as valuable food material in Korea. The composition and contents of bioactive compounds in the fruit can be influenced by its maturity stages. In this study, total phenol, total flavonoid, individual polyphenolic compounds, total carotenoids and antioxidant activities at four maturity stages of the fruit were determined. Polyphenolic compounds were analyzed using high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry (HPLC-QTOF-MS) and HPLC. Among 18 polyphenolic compounds identified in this study, five parishin derivatives (gastrodin, parishin A, B, C, E) were positively identified for the first time in this plant. These compounds were also validated and quantified using authentic standards. Parishin A was the most abundant component, followed by chlorogenic acid, gastrodin, eriodictyol glucoside, parishin C, parishin E and parishin B. The contents of all the polyphenolic compounds were higher at the immature and premature stages than at fully mature and overmature stages, while total carotenoid was found to be higher in the mature and overmature stages. Overall antioxidant activities by three different assays (DPPH, ABTS, FRAP) decreased as maturation progressed. Antioxidant properties of the fruit extract are suggested to be attributed to the polyphenols.

Antibacterial and antioxidant effects of Zanthoxylum armatum DC extracts

2021 ◽  
Vol 50 (1) ◽  
pp. 159-164
Author(s):  
Aqsa Irshad ◽  
Irfan Ullah ◽  
Muhammad Fiaz Khan
Keyword(s):  
Antioxidant Activity ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Inhibition Zone ◽  
Fruit Extract ◽  
Zanthoxylum Armatum ◽  
Good Antibacterial Activity ◽  
Maximum Inhibition ◽  
Hexane Extracts ◽  
Antioxidant Effects

Antibacterial and antioxidant activities of three different extracts (acetone, methanol, and n-hexane) of Zanthoxylum armatum fruits and leaves were investigated. The maximum inhibition zone was shown by methanolic leaf extract against K. pneumonia (20.51 ± 0.93). The minimum inhibition zone (12.01 ± 0.93) was exhibited by methanolic fruit extract against S. typhi. The highest antioxidant activity was recorded at 1000 ppm. Methanolic leaf extract was the most antioxidant (89.8%) among all the extracts, followed by methanolic fruit extract (88.6%). The methanolic and acetonic extracts showed good antibacterial activity as compared to n-hexane extracts and n-hexane was less antioxidant.

Flavones and Their Analogues as Bioactive Compounds – An Overview

2019 ◽  
Vol 16 (4) ◽  
pp. 377-391 ◽  
Author(s):  
B.S. Jayashree ◽  
H. Venkatachalam ◽  
Sanchari Basu Mallik
Keyword(s):  
Biological Activity ◽  
Free Radical ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Cost Effective ◽  
Free Radical Scavenging ◽  
Polyphenolic Compounds ◽  
Pharmacological Activities ◽  
Poor Solubility

Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacological activities. Even though, natural flavonoids are highly potent, owing to their poor solubility, they are less used. Therefore, attempts have been made to improve their stability, solubility, efficacy and kinetics by introducing various substituents on the flavone ring. For nearly the last two decades, flavones were synthesized in our laboratory by simple, convenient and cost-effective methods, with the knowledge of both synthetic and semi-synthetic chemistry. In this direction, it was considered worthwhile to present an overview on the synthesized flavonoids. This review creates a platform for highlighting various modifications done on the flavone system along with their biological activity.

scholarly journals Bioactive Compounds, Antioxidant Activity and Growth Behavior in Lettuce Cultivars Grown under Field and Greenhouse Conditions

Proceedings ◽  
2020 ◽  
Vol 70 (1) ◽  
pp. 52
Author(s):  
Melisa Lanza Volpe ◽  
Verónica C. Soto Vargas ◽  
Anabel Morón ◽  
Roxana E. González
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Growth Conditions ◽  
Growth Behavior ◽  
Total Phenolic ◽  
Spectrophotometric Methods ◽  
Leafy Greens ◽  
Growing Conditions ◽  
Field Production

Lettuce (Lactuca sativa L.) is one of the most important leafy greens worldwide. The nutritional value of its edible leaf depends on different factors including type and growing conditions. The aim was to determine the bioactive compounds content, antioxidant activity and growth behavior of twenty-two lettuce genotypes, cultivated under field and greenhouse conditions. Total phenolic compound, chlorophylls, carotenoids, anthocyanin contents and antioxidant activities were analyzed by spectrophotometric methods. Data were analyzed by analysis of variance (ANOVA). Significant differences between bioactive compounds, antioxidant activity and growth behavior were found among cultivars and morphological types, for both growth conditions. Carotenoid and chlorophyll content was higher in greenhouse conditions for all genotypes. In field production, butterhead and iceberg lettuces showed lower content of these bioactive compounds. The red-pigmented Falbala cultivar from field production showed the highest level of polyphenols and anthocyanin. Meanwhile, in greenhouse conditions, the oak leaf cultivar Grenadine displayed the highest concentration of these phenolic compounds. The iceberg type lettuce showed the lowest percentages of antioxidant activity in both environments. The results showed the effect of growing conditions and the high variability in lettuce bioactive compounds content and antioxidant activity among the different types.

scholarly journals New insights of phenolic compounds from optimized fruit extract of Ficus auriculata

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Shahinuzzaman ◽  
Parul Akhtar ◽  
N. Amin ◽  
Yunus Ahmed ◽  
Farah Hannan Anuar ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Fruit Extract ◽  
Optimum Extraction

AbstractIn this study, the extraction conditions extracted maximize amounts of phenolic and bioactive compounds from the fruit extract of Ficus auriculata by using optimized response surface methodology. The antioxidant capacity was evaluated through the assay of radical scavenging ability on DPPH and ABTS as well as reducing power assays on total phenolic content (TPC). For the extraction purpose, the ultrasonic assisted extraction technique was employed. A second-order polynomial model satisfactorily fitted to the experimental findings concerning antioxidant activity (R2 = 0.968, P < 0.0001) and total phenolic content (R2 = 0.961, P < 0.0001), indicating a significant correlation between the experimental and expected value. The highest DPPH radical scavenging activity was achieved 85.20 ± 0.96% at the optimum extraction parameters of 52.5% ethanol (v/v), 40.0 °C temperature, and 22 min extraction time. Alternatively, the highest yield of total phenolic content was found 31.65 ± 0.94 mg GAE/g DF at the optimum extraction conditions. From the LC–ESI–MS profiling of the optimized extract, 18 bioactive compounds were tentatively identified, which may regulate the antioxidant activity of fruits of F. auriculata.

scholarly journals Pharmacological and Antioxidant Activities of Rhus coriaria L. (Sumac)

Antioxidants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 73
Author(s):  
Halima Alsamri ◽  
Khawlah Athamneh ◽  
Gianfranco Pintus ◽  
Ali H. Eid ◽  
Rabah Iratni
Keyword(s):  
Cardiovascular Disease ◽  
Mediterranean Region ◽  
Molecular Mechanisms ◽  
Antioxidant Activities ◽  
Polyphenolic Compounds ◽  
Therapeutic Benefits ◽  
Anticancer Effects ◽  
Antioxidant Capacities ◽  
Rhus Coriaria ◽  
Flavoring Agent

Rhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in traditional medicine for the management and treatment of many ailments including hemorrhoids, wound healing, diarrhea, ulcer, and eye inflammation. This plant is rich in various classes of phytochemicals including flavonoids, tannins, polyphenolic compounds, organic acids, and many others. By virtue of its bioactive, Rhus coriaria possesses powerful antioxidant capacities that have ameliorative and therapeutic benefits for many common diseases including cardiovascular disease, diabetes, and cancer. This review describes the phytochemical properties of R. coriaria and then focuses on the potent antioxidant capacities of sumac. We then dissect the cellular and molecular mechanisms of sumac’s action in modulating many pathophysiological instigators. We show how accumulating evidence supports the antibacterial, antinociceptive, antidiabetic, cardioprotective, neuroprotective, and anticancer effects of this plant, especially that toxicity studies show that sumac is very safe to consume by humans and has little toxicity. Taken together, the findings we summarize here support the utilization of this plant as an attractive target for drug discovery.

scholarly journals IN VITRO ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF HINGULESWARA RASABASED HERBOMINERAL FORMULATIONS

2018 ◽  
Vol 11 (14) ◽  
pp. 24
Author(s):  
Abhishek Chatterjee ◽  
Dileep Singh Baghel ◽  
Bimlesh Kumar ◽  
Saurabh Singh ◽  
Narendra Kumar Pandey ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Standard Drug ◽  
Three Samples ◽  
Anti Inflammatory ◽  
Dose Dependent ◽  
Antioxidant Effects ◽  
Made In ◽  
In Vitro Antioxidant Activity

Objective: The aims of the present investigation were to develop the herbal and/or herbomineral formulations of Hinguleswara rasa and to compare their anti-inflammatory and antioxidant activities, in vitro, with that of standard drug samples.Methods: This study was an interventional investigation in three samples: In the first sample, Hinguleswara rasa (HR1) was prepared as per methodology described in Rasatarangini using Shuddha Hingula (10 g), Shuddha Vatsanabha (10 g), and Pippali (10 g). In the second and third sample, respectively, Hinguleswara rasa was prepared by replacing Shuddha Hingula with Kajjali where Kajjali made from Hingulotha parada and Sodhita parada constitutes two varieties of Hinguleswara rasa, i.e. HR2 and HR3. In vitro antioxidant activity was studied using 2,2-diphenyl-1-picrylhydrazyl, and the absorbance was recorded at 517 nm. For evaluating the in vitro anti-inflammatory studies, the inhibition of albumin denaturation technique was performed.Results: The results showed that the formulation of Hinguleswara rasa has shown dose-dependent activity which was observed in 100 μg concentration. HR1, HR2, and HR3 showed 36.11, 17.22, and 16.11% radical scavenging activity.Conclusion: It could be concluded that the changes made in the formulations did not affect the in vitro anti-inflammatory and antioxidant effects of the herbomineral formulations.

Bioactive compounds and antioxidant activities of Brazilian hop ( Humulus lupulus L.) extracts

2019 ◽  
Vol 55 (1) ◽  
pp. 340-347 ◽  
Author(s):  
Aline da Rosa Almeida ◽  
Matheus Vinícius de Oliveira Brisol Maciel ◽  
Michelle Heck Machado ◽  
Giovana Carolina Bazzo ◽  
Rafael Dutra Armas ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Humulus Lupulus ◽  
Humulus Lupulus L

Bioactive Compounds, High Performance Liquid Chromatography Screening of Phenolic Compounds, and Antioxidant Potential Activity of Saffron (Crocus sativus L.)

2021 ◽  
Vol 15 (5) ◽  
pp. 700-704
Author(s):  
Mohammed Saeed Alkaltham ◽  
Khizar Hayat ◽  
Mohammed Asif Ahmed ◽  
Ahmad Mohammad Salamatullah ◽  
Rokayya Sami ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Bioactive Compounds ◽  
High Performance ◽  
Antioxidant Activities ◽  
Reducing Power ◽  
Saudi Arabian ◽  
Crocus Sativus ◽  
Potential Activity ◽  
Different Origins ◽  
Crocus Sativus L

Saffron (Crocus sativus L) has been widely used for many therapeutic purposes such as a pain reliever, inflammation cure due to the highly bioactive compounds, and antioxidant activities. The effect of boiling time (5, 10, and 15 min) was investigated on the bioactive compounds of saffron samples from different origins (Spain, Saudi Arabia, and Afghanistan). Depending on the origin of the saffron sample, the extraction time showed a different effect on their total polyphenol content (TPC). The highest TPC was noted in saffron from Spain boiled for 10 min (45.01 mg GAE/g DW), followed by the sample from Saudi Arabia (44.03 mg GAE/g DW) and Afghanistan (43.54 mg GAE/g DW) boiled for 15 min, respectively. The Spanish saffron extracted for 10 min significantly (p < 0.05) exhibited the highest total flavonoid content (TFC) (12.26 mg CE/g DW), while the Saudi saffron extracted for 5 min (6.06 mg CE/g DW) showed the lowest range among all the samples. There were no significant differences among the reducing power of Saudi Arabian saffron extracted for 10 min, and Spanish saffron extracted for 5 and 15 min, respectively. The reducing power of saffron samples echoed the results of the TPC and TFC. 1,2-DHB (dihydroxy benzene), chlorogenic acid, caffeic acid are increased upon the increase of boiling time in Saudi Arabian saffron samples. In a word, 10 min and 15 min boiling times achieved the best extraction for Spanish saffron followed by Saudi and Afghani saffron samples, respectively.

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