scholarly journals A Meta-Analysis on the Impact of the Supplementation of Rumen-Protected Choline on the Metabolic Health and Performance of Dairy Cattle

Animals ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 566 ◽  
Author(s):  
Humer ◽  
Bruggeman ◽  
Zebeli

After parturition, cows undergo negative energy balance leading to fat mobilization, predisposing them to fatty liver syndrome and ketosis with major consequences for health and reproduction. Supplementation of rumen-protected choline (RPC) has attracted major research efforts during the last decade, assuming that choline improves liver function by increasing very low-density lipoprotein exportation from the liver, thereby improving metabolic profiles, milk production, and reproduction. However, the effects of RPC on production, health, and reproduction have been inconsistent. Therefore, the aim of this meta-analysis was to evaluate the effects of RPC supplementation, starting from d 20 (± 12.2) ante partum to d 53 (± 31.0) postpartum, on feed intake, milk production performance and metabolic profiles of dairy cows early postpartum. Data analyses from 27 published studies showed an increase in postpartal dry matter intake (from on average 19.1 to 19.9 kg/d; p < 0.01) and milk yield (from on average 31.8 to 32.9 kg/d; p = 0.03) in cows receiving RPC. Milk fat yield and milk protein yield were also increased (p ≤ 0.05), without changing milk protein and fat contents. However, no interactive effects between cow’s milk yield level and RPC-supplementation as well as no dose-dependent effects of RPC supplementation were observed. Supplementing the diet with RPC showed no effects on blood metabolites (non-esterified fatty acids, beta-hydroxybutyrate, glucose, and cholesterol), independent of the milk yield level of the cows. An effect on liver triacylglycerol contents, incidence of ketosis, and mastitis could not be confirmed across all studies included in this meta-analysis. Also, the positive effects of RPC supplementation on reproductive performance were not consistent findings. In conclusion, supplementing RPC in lactating dairy cows showed positive effects on dry matter intake which likely caused the improved milk yield. However, RPC supplementation did not improve the metabolic health status of the cows. As several factors might be related to the responses to RPC, further research is needed to explore the precise mechanisms of RPC action in lactating cows, especially with regards to feed intake improvement and its related metabolic health-promoting potential in early lactating dairy cows.

Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 104
Author(s):  
Shulin Liang ◽  
Chaoqun Wu ◽  
Wenchao Peng ◽  
Jian-Xin Liu ◽  
Hui-Zeng Sun

The objective of this study was to evaluate the feasibility of using the dry matter intake of first 2 h after feeding (DMI-2h), body weight (BW), and milk yield to estimate daily DMI in mid and late lactating dairy cows with fed ration three times per day. Our dataset included 2840 individual observations from 76 cows enrolled in two studies, of which 2259 observations served as development dataset (DDS) from 54 cows and 581 observations acted as the validation dataset (VDS) from 22 cows. The descriptive statistics of these variables were 26.0 ± 2.77 kg/day (mean ± standard deviation) of DMI, 14.9 ± 3.68 kg/day of DMI-2h, 35.0 ± 5.48 kg/day of milk yield, and 636 ± 82.6 kg/day of BW in DDS and 23.2 ± 4.72 kg/day of DMI, 12.6 ± 4.08 kg/day of DMI-2h, 30.4 ± 5.85 kg/day of milk yield, and 597 ± 63.7 kg/day of BW in VDS, respectively. A multiple regression analysis was conducted using the REG procedure of SAS to develop the forecasting models for DMI. The proposed prediction equation was: DMI (kg/day) = 8.499 + 0.2725 × DMI-2h (kg/day) + 0.2132 × Milk yield (kg/day) + 0.0095 × BW (kg/day) (R2 = 0.46, mean bias = 0 kg/day, RMSPE = 1.26 kg/day). Moreover, when compared with the prediction equation for DMI in Nutrient Requirements of Dairy Cattle (2001) using the independent dataset (VDS), our proposed model shows higher R2 (0.22 vs. 0.07) and smaller mean bias (−0.10 vs. 1.52 kg/day) and RMSPE (1.77 vs. 2.34 kg/day). Overall, we constructed a feasible forecasting model with better precision and accuracy in predicting daily DMI of dairy cows in mid and late lactation when fed ration three times per day.


Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3545
Author(s):  
Layla King ◽  
Janaka Wickramasinghe ◽  
Brooke Dooley ◽  
Carrie McCarthy ◽  
Emily Branstad ◽  
...  

The study objective was to determine the effects of rumen-protected methionine (Met) by microencapsulation (RPM) on amino acid (AA) supply to the udder, milk production, and manure nitrogen (N) losses of dairy cows. A corn and soybean-based diet deficient in metabolizable Met (~10 g/d) was supplemented with RPM providing 0, 11.0, 19.3, and 27.5 g/d of Met. Dry matter intake (DMI), milk production, plasma essential AA (EAA), mammary plasma flow (MPF), and fecal (FN) and urinary N (UN) outputs (g/d) were determined. The RPM increased linearly milk yield, milk protein yield, and energy corrected milk yield (p < 0.040) without affecting DMI. Milk protein yield increased by 50 g/d for the 19.3 vs. 0 g/d dose (p = 0.006) but the rate of increment decreased for 27.5 g/d dose. Plasma Met, and MPF increased linearly with RPM dose (p < 0.050). Apparent total tract digestibility of crude protein (p = 0.020) and FN (p = 0.081) decreased linearly with RPM. The UN did not change but total manure N decreased linearly with RPM (p = 0.054). The RPM (19.3 g/d) seemed to help cows overcome the metabolizable Met deficiency while mitigating manure N excretions to the environment.


2021 ◽  
Vol 12 (4) ◽  
pp. 491-497
Author(s):  
Diana Marcela Valencia E ◽  
Luis Alfonso Giraldo ◽  
Alejandra Marin ◽  
Yury Tatiana Granja Salcedo ◽  
Telma Teresinha Berchielli

1984 ◽  
Vol 115 (11) ◽  
pp. 278-278
Author(s):  
J. Mackinnon ◽  
R. McGuffey ◽  
H. Green

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 379-379
Author(s):  
Susanna Räisänen ◽  
Alexander N Hristov

Abstract The objective of this meta-analysis was to examine the effect of supplemental histidine (His) on dry matter intake (DMI), milk (MY) and energy-corrected milk (ECM) yields, and milk components in lactating dairy cows. A comprehensive meta-analysis was performed to data from 20 studies published in peer-reviewed journals between 1999 and 2021. In 12 of the studies His was supplemented to the diet as rumen-protected His and in the remaining experiments free His was infused into the abomasum (5 experiments), the jugular vein (2 experiments) or the duodenum (1 experiment) of the cows. The diets were based on corn silage in 60% and on grass silage in 40% of the studies. In studies where data were available (13 out of 20), metabolizable protein supply was estimated to be on average 98% (min = 85% and max = 110%) of NRC (2001) requirements. Computations were carried out using Comprehensive Meta-Analysis (V. 3.3.070). Histidine supplementation increased (P &lt; 0.001) plasma His concentration by 59%, compared with control. Dry matter intake and MY increased (P ≤ 0.002) by 0.22 and 0.36 kg/d, respectively, whereas ECM yield tended to increase (P = 0.07) by 0.14 kg/d with His supplemented diets vs. the control. Milk protein concentration was also increased (P = 0.004) by 0.20 %-units, whereas milk fat concentration tended to decrease (P = 0.10) by 0.11 %-units with His supplementation. Further, His increased milk protein and lactose yield (P ≤ 0.05) by 0.31 and 0.14 kg/d, respectively. Overall, based on the available data, His supplementation of lactating dairy cow rations enhanced DMI, MY and milk protein concentration and yield.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 294-294
Author(s):  
Laura A Smith ◽  
Allen Y Young ◽  
Chris Pratt ◽  
Kara J Thornton

Abstract Alfalfa is a commonly grown forage in the Intermountain west and is often included in lactating dairy cow rations. This study investigated the effects of including novel alfalfa products: ProLEAF MAX™ (PLM), an alfalfa leaf pellet; and ProFiber Plus™ (PFP), alfalfa stems, in the diet of lactating dairy cows on dry matter intake, milk yield, and milk components. Holstein cows were housed in a freestall barn and milked in a free-flow automatic milking system. All cows were fed each treatment for 21-days, then switched to the next treatment utilizing a crossover experimental design. The five treatments were: control (CON, typical diet including alfalfa hay; n = 65); low-quality alfalfa hay (LQ+PLM, a diet that replaced alfalfa hay with low-quality alfalfa hay and PLM; n = 62); PLM+PFP (a diet that replaced alfalfa hay with PLM and PFP; n = 65); PLM (a diet that replaced alfalfa hay with PLM; n = 62); and PFP (a diet that replaced alfalfa hay with PFP; n = 60). Cows were group fed a partial mixed ration balanced for 40.8 kg milk, 3.9% milk fat and 3.3% milk protein. Individual milk yield and milk components were recorded daily by the automatic milking system. Dry matter intake was also recorded daily. When fed the PFP diet, cows had decreased (P &lt; 0.01) dry matter intake compared to the other diets. Milk yield was increased (P &lt; 0.01) when cows received the PLM diet when compared to the other diets. When fed the PFP and PLM+PFP diets, milk fat was increased (P &lt; 0.01) when compared to the other diets. Milk protein was decreased (P &lt; 0.01) when cows were fed the PFP diet when compared to the other diets. These data indicate that inclusion of fractionated alfalfa products in the diet of lactating dairy cows has the potential to increase milk yield and milk components.


Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 373 ◽  
Author(s):  
Ignacio E. Beltrán ◽  
Omar Al-Marashdeh ◽  
Ana R. Burgos ◽  
Pablo Gregorini ◽  
Oscar A. Balocchi ◽  
...  

The aim of this study was to evaluate the effects of the order of grass silage (GS) and maize silage (MS) supplementation on milk yield, grazing behavior and nitrogen (N) partitioning of lactating dairy cows during autumn. Thirty-six Holstein-Friesian dairy cows were randomly assigned to one of three treatments, and cows remained on these treatments for a 62 days period: (1) MIX; cows supplemented with 3 kg of dry matter (DM) of silage containing 1.5 kg DM of MS and 1.5 kg DM of GS in both the morning and afternoon; (2) GS-MS; cows supplemented with 3 kg DM of GS in the morning and 3 kg DM of MS in the afternoon; (3) MS-GS; cows supplemented with 3 kg DM of MS in the morning and 3 kg DM of GS in the afternoon. All cows received a pasture allowance of 17 kg DM/cow/d and 3 kg DM of concentrate. Grazing time and pasture intake were unaffected by treatment; however, milk production was greater for MS-GS, while milk protein was greater for GS-MS. Urinary N excretion was greater for MS-GS than MIX. In conclusion, MS-GS resulted in high milk yield but also high urinary N excretion, while MIX resulted in low urinary N excretion but also decreased milk yield.


1989 ◽  
Vol 69 (1) ◽  
pp. 195-203 ◽  
Author(s):  
P. H. ROBINSON ◽  
J. J. KENNELLY

Three dairy cows with large rumen cannulae were fed totally mixed diets twice daily. Diets contained 49% whole crop oat silage, 38.5% high-moisture barley (HMB), and 12.5% protein-mineral-vitamin supplement on a dry matter (DM) basis. HMB had been ammoniated at target levels of 0, 0.65, 1.30, and 1.95 g per 100 g HMB DM. Actual levels achieved were 0, 0.63, 1.30, and 1.95 g ammonia per 100 g. Apparent digestibility of organic matter (OM), neutral detergent (ND) fiber, starch, and N were not significantly influenced by level of ammoniation of HMB, although there was a trend for increased N digestion. Total rumen pool sizes of wet ingesta and DM were not influenced by ammoniation levels of HMB, although proportion of ND fiber in rumen OM declined as level of ammoniation of HMB increased. Milk yield and production of milk protein and lactose increased as level of ammoniation of HMB increased. Data are interpreted to suggest that rumen digestion of dietary nonfiber components declined as level of ammoniation of HMB increased, although digestion of ND fiber was not influenced. These results support the hypothesis that ammoniation of HMB shifted the site of digestion of a portion of the dietary nonfiber component from the rumen to the intestine without influencing rumen microbial pool sizes or degradative activity. Greater energetic efficiency of intestinal digestion of dietary nonfiber components, as level of ammoniation of HMB increased, may have contributed to the increased milk yield. Key words: Barley (high-moisture), ammoniation, dairy cows, digestion


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