scholarly journals A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs

Animals ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3094
Author(s):  
Pagona Gouletsou ◽  
Nikitas Prassinos ◽  
Lysimachos Papazoglou ◽  
Polychronis Kostoulas ◽  
Apostolos Galatos
Keyword(s):  
Comparative Evaluation ◽  
Controlled Trial ◽  
Healing Process ◽  
Histological Evaluation ◽  
Beagle Dogs ◽  
Suture Materials ◽  
Experimental Animals ◽  
Clinical Appearance ◽  
Cosmetic Appearance ◽  
Poliglecaprone 25

The objective of this work was the comparative evaluation of the healing process after employing 4/0 poliglecaprone 25 and 4/0 polyglytone 6211 in a continuous intradermal suture pattern. Ten Beagle dogs were used, in which skin incisions were created surgically and subsequently were sutured by means of continuous intradermal pattern using polyglytone 6211 or poliglecaprone 25 suture. Cosmetic, clinical, and histologic scores were evaluated. The cosmetic appearance of the wounds was blindly evaluated on days 7, 14, 28, 180, 360, 730, and 1095. On the same days, tissue biopsy was performed for histological evaluation. Clinical evaluation was performed initially daily, then weekly, monthly, and finally yearly, till day 1095. The clinical appearance of the intradermal pattern with both sutures was initially very good, deteriorated in the second post-operative month and thereafter improved. The cosmetic, clinical, and histological differences between the two suture materials were minimal and statistically insignificant. Polyglytone 6211 is sufficient for use in intradermal suturing in dogs. However, its earlier absorption compared to poliglecaprone 25 did not have any beneficial effect on cutaneous wound healing and scar appearance in the experimental animals.

scholarly journals The effects of luteolin nanoparticles on the healing of extracted tooth socket in rabbits.

2019 ◽  
Vol S (1) ◽  
pp. 15-18
Author(s):  
Maha T. Al-Saffar ◽  
◽  
Amer A. Taqa ◽  
Keyword(s):  
Tooth Extraction ◽  
Healing Process ◽  
Histological Evaluation ◽  
Maxillary Incisor ◽  
Control Group ◽  
Experimental Animals ◽  
Tooth Socket ◽  
Socket Healing ◽  
Hematoxylin And Eosin ◽  
Luteolin Treatment

Objective: To evaluate the effects of luteolin nanoparticles on the process tooth socket healing in rabbits. Design: This study comprised five rabbits randomly assigned to control animal and experimental animals. Immediately after the extraction of an upper maxillary incisor, the alveolar sockets of experimental animals were treated with topical luteolin while alveolar sockets of the control group remained without treatment. The animals were sacrificed by decapitation with deep anesthesia seven days post tooth extraction. The tooth sockets were sectioned and stained with hematoxylin and eosin stains. Results: Histological evaluation revealed that luteolin treatment induced earlier healing of extracted tooth sockets. Conclusion: These findings suggest that luteolin accelerates the healing process in tooth sockets of rabbits.

Histological evaluation of extraction sites grafted with Bio-Oss Collagen: Randomized controlled trial

2021 ◽  
Vol 237 ◽  
pp. 151722
Author(s):  
Christiane Keil ◽  
Barbara Gollmer ◽  
Ines Zeidler-Rentzsch ◽  
Tomasz Gredes ◽  
Friedhelm Heinemann
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Histological Evaluation ◽  
Randomized Controlled

scholarly journals Initial Tests on Selected Serological Reactions in Rabbits Burnt with Napalm and Subjected to Hyperbaric Oxygenation

2015 ◽  
Vol 50 (1) ◽  
pp. 41-45
Author(s):  
Kazimierz Ulewicz ◽  
Przemysław Michniewski ◽  
Brunon Kierznikowicz ◽  
Bogdan Łokucijewski ◽  
Jan Stencel
Keyword(s):  
Hyperbaric Oxygenation ◽  
Healing Process ◽  
Control Group ◽  
Complement Activity ◽  
Experimental Animals ◽  
Burn Wounds ◽  
Immunological Reactions

Abstract Hyperbaric oxygenation therapy has found its application in the treatment of various types of burns. The presented work describes the use of this method in treating napalm burns in experimental animals. The researchers took particular interest in the immunological reactions occurring in animals, as well as the effect of the said therapy on the healing process. Two groups of rabbits, previously anaesthetised with Evipan and immunised with S. typhi phage F7 microorganisms, were burnt with the use of napalm. The tested group was subjected to a series of treatment sessions with 100% oxygen at the pressure of 2 atm, whereas the control group did not undergo such treatment. Six repeated tests on complement activity with 50% haemolysis method and heamagglutination reaction quantification with antigens O and H S.typhi phage F7 were carried out on all of the researched animals. Moreover, for the purpose of control of the healing process, a number of histopathological exams on the burn wounds were conducted in both groups of rabbits. The research showed an increase in complement activity in all tested animals; however, in the tested group it occurred later. Histopathological tests confirmed a more advanced healing process in the group subjected to hyperbaric oxygenation.

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