scholarly journals Decreased Size of Mammary Tumors Caused by Preoperative Treatment with Aglepristone in Female Domestic Dogs (Canis familiaris) Do Not Influence the Density of the Benign Neoplastic Tissue Measured Using Shear Wave Elastography Technique

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 527 ◽  
Author(s):  
Barbara Pieczewska ◽  
Kamila Glińska-Suchocka ◽  
Wojciech Niżański ◽  
Michał Dzięcioł
Keyword(s):  
Shear Wave ◽  
Tumor Size ◽  
Histopathological Examination ◽  
Shear Wave Elastography ◽  
Mammary Tumors ◽  
Needle Aspiration ◽  
Surgical Removal ◽  
Preoperative Treatment ◽  
Neoplastic Tissue ◽  
Before And After

Shear wave elastography (SWE) can be useful to discriminate between malignant and benign mammary tumors. In dogs with elevated progesterone levels compared to the baseline and fast-growing tumors, treatment with the use of aglepristone allows for tumor size reduction, which facilitates surgery. This study aimed to evaluate the influence of the preoperative treatment of benign mammary tumors (BMTs), performed with the use of aglepristone, on the density of the tumor tissue measured by SWE. Twelve female dogs with diagnosed BMTs and increased levels of progesterone were treated with aglepristone (Alizine, Virbac, France) at 10 mg/kg s.c. (Subcutaneous injection). twice, with a 24 h interval. The density of the tumor was evaluated by SWE before and after the treatment. The type of tumor was evaluated by fine needle aspiration cytology before treatment, and a histopathological examination was made after surgical removal, performed after the aglepristone treatment. In all the cases, a significant reduction in the mammary tumor’s size was observed following treatment, with no influence on the density of the tumor’s tissue measured by SWE. Similar studies on malignant mammary tumors are warranted to verify if in these cases, density will also be a constant parameter that is not dependent on the tumor size.

scholarly journals Shear wave elastography in hepatitis C patients before and after antiviral therapy

2017 ◽  
Vol 9 (1) ◽  
pp. 64 ◽  
Author(s):  
Toshikuni Suda ◽  
Osamu Okawa ◽  
Rion Masaoka ◽  
Yoshinori Gyotoku ◽  
Naohiko Tokutomi ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Antiviral Therapy ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Before And After

Effect of Rest Duration Between Static Stretching on Passive Stiffness of Medial Gastrocnemius Muscle In Vivo

2020 ◽  
Vol 29 (5) ◽  
pp. 578-582
Author(s):  
Masatoshi Nakamura ◽  
Shigeru Sato ◽  
Ryosuke Kiyono ◽  
Nobushige Takahashi ◽  
Tomoichi Yoshida
Keyword(s):  
Elastic Modulus ◽  
Shear Wave ◽  
Repeated Measures ◽  
Shear Wave Elastography ◽  
Muscle Stiffness ◽  
Medial Gastrocnemius ◽  
Static Stretching ◽  
Shear Elastic Modulus ◽  
Before And After

Context: In clinical and sports settings, static stretching (SS) is usually performed to increase range of motion (ROM) and decrease passive muscle stiffness. Recently, the shear elastic modulus was measured by ultrasonic shear wave elastography as an index of muscle stiffness. Previous studies reported that the shear elastic modulus measured by ultrasound shear wave elastography decreased after SS, and the effects of SS on shear elastic modulus were likely affected by rest duration between sets of SS. Objective: To investigate the acute effects of SS with different rest durations on ROM and shear elastic modulus of gastrocnemius and to clarify whether the rest duration between sets of SS decreases the shear elastic modulus. Design: A randomized, repeated-measures experimental design. Setting: University laboratory. Participants: Sixteen healthy males volunteered to participate in the study (age 21.3 [0.8] y; height 171.8 [5.1] cm; weight 63.1 [4.5] kg). Main Outcome Measures: Each participant underwent 3 different rest interval durations during SS (ie, long rest duration: 90 s; normal rest duration: 30 s; and short rest duration: 10 s). This SS technique was repeated 10 times, thus lasting a total of 300 seconds with different rest durations in each protocol. The dorsiflexion ROM and shear elastic modulus were measured before and after SS. Results: Our results revealed that dorsiflexion ROM and shear elastic modulus were changed after 300-second SS; however, no effects of the rest duration between sets of SS were observed. Conclusions: In terms of decreasing the shear elastic modulus, clinicians and coaches should not focus on the rest duration when SS intervention is performed.

scholarly journals Shear wave elastography of lumbar annulus fibrosus in adolescent idiopathic scoliosis before and after surgical intervention

2019 ◽  
Vol 30 (4) ◽  
pp. 1980-1985
Author(s):  
Claudio Vergari ◽  
Lucas Chanteux ◽  
Raphael Pietton ◽  
Tristan Langlais ◽  
Raphael Vialle ◽  
...  
Keyword(s):  
Adolescent Idiopathic Scoliosis ◽  
Idiopathic Scoliosis ◽  
Shear Wave ◽  
Annulus Fibrosus ◽  
Surgical Intervention ◽  
Shear Wave Elastography ◽  
Before And After

scholarly journals Comparing the Sensitivity and Specificity of Two-Dimensional Shear Wave Elastography and Fine Needle Aspiration in Determining Malignant Thyroid Nodules

2019 ◽  
Vol 8 (1) ◽  
pp. 30
Author(s):  
SayyidAmir Tabatabaei ◽  
Maryam Farghadani ◽  
Roozbeh Barikbin ◽  
Armindokht Shahsanai ◽  
Maryam Riahinezhad ◽  
...  
Keyword(s):  
Shear Wave ◽  
Sensitivity And Specificity ◽  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Shear Wave Elastography ◽  
Needle Aspiration ◽  
Two Dimensional ◽  
Fine Needle

scholarly journals Diagnostic Performance of a Combination of Shear Wave Elastography and B-Mode Ultrasonography in Differentiating Benign From Malignant Thyroid Nodules

2020 ◽  
Vol 13 (2) ◽  
pp. 186-193
Author(s):  
Eung Koo Yeon ◽  
Yu-Mee Sohn ◽  
Mirinae Seo ◽  
Eui-Jong Kim ◽  
Young-Gyu Eun ◽  
...  
Keyword(s):  
Shear Wave ◽  
Predictive Value ◽  
Diagnostic Performance ◽  
Thyroid Nodules ◽  
Multivariate Logistic Regression Analysis ◽  
Shear Wave Elastography ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
The Difference ◽  
Us Findings

Objectives. This study was conducted to compare clinicopathologic and radiologic factors between benign and malignant thyroid nodules and to evaluate the diagnostic performance of shear wave elastography (SWE) combined with B-mode ultrasonography (US) in differentiating malignant from benign thyroid nodules.Methods. This retrospective study included 92 consecutive patients with 95 thyroid nodules examined on B-mode US and SWE before US-guided fine-needle aspiration biopsy or surgical excision. B-mode US findings (composition, echogenicity, margin, shape, and calcification) and SWE elasticity parameters (maximum [E<sub>max</sub>], mean, minimum, and nodule-to-normal parenchymal ratio of elasticity) were reviewed and compared between benign and malignant thyroid nodules. The diagnostic performance of B-mode US and SWE for predicting malignant thyroid nodules was analyzed. The optimal cutoff values of elasticity parameters for identifying malignancy were determined. Diagnostic performance was compared between B-mode US only, SWE only, and the combination of B-mode US with SWE.Results. On multivariate logistic regression analysis, age (odds ratio [OR], 0.90; <i>P</i>=0.028), a taller-than-wide shape (OR, 11.3; <i>P</i>=0.040), the presence of calcifications (OR, 15.0; <i>P</i>=0.021), and E<sub>max</sub> (OR, 1.22; <i>P</i>=0.021) were independent predictors of malignancy in thyroid nodules. The combined use of B-mode US findings and SWE yielded improvements in sensitivity, the positive predictive value, the negative predictive value, and accuracy compared with the use of B-mode US findings only, but with no statistical significance.Conclusion. When SWE was combined with B-mode US, the diagnostic performance was better than when only B-mode US was used, although the difference was not statistically significant.

scholarly journals Evaluation of Functional Recovery Following Achilles Tendon Ruptures by Shear Wave Elastography: A Before-and-After Study

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Donglin Bian ◽  
Xuemei Wang ◽  
Kun Huang ◽  
Zhen Zhang
Keyword(s):  
Achilles Tendon ◽  
Shear Wave ◽  
Functional Recovery ◽  
Shear Wave Elastography ◽  
Postoperative Recovery ◽  
Postoperative Function ◽  
Time Points ◽  
Before And After ◽  
Tendon Ruptures ◽  
The Mean

Background: Sonoelastography is extensively used for clinical diagnosis. Different types of elastography can be used to assess the elastic properties (stiffness) of tissues. For quantitative analyses, shear wave elastography (SWE) has been applied as a non-invasive method in the past decade. Today, SWE is widely used for diagnosing diseases. However, a limited number of studies have investigated musculoskeletal injuries and neoplastic diseases. Objectives: This study aimed to evaluate the postoperative functional recovery of Achilles tendon ruptures by SWE to determine the Achilles tendon function and provide reliable evidence for clinicians. Methods: SWE was used to measure elasticity in 67 patients with Achilles tendon ruptures. In the postoperative stage, 17 patients were lost to follow-up. The remaining 50 patients with Achilles tendon ruptures were examined. Each patient was followed-up for one, three, and six months postoperatively. The 0° flexion of the ankle joint was considered as the standard position. The mean elasticity (Emean) of the Achilles tendon was measured and recorded at different time points before and after surgery. Besides, the thickness and width of the Achilles tendon were measured at the corresponding time points. Results: The mean elasticity (Emean) of normal and ruptured Achilles tendons was 447.4 ± 59.57 and 63.84 ± 45.18 kPa, respectively in 50 patients with ruptured Achilles tendons before surgery. On the other hand, the Emean values of ruptured Achilles tendons in one-, three-, and six-month follow-ups were 110.3 ± 35.60, 183.4 ± 46.08, and 279.1 ± 48.18 kPa in 50 patients, respectively. Regarding the Emean, the difference between the five time points was significant (F = 418.5, P < 0.01). With prolongation of postoperative recovery, the Emean of the Achilles tendon gradually increased; the Emean value significantly increased at six months after surgery. Conclusions: The quantitative analysis of the postoperative function of Achilles tendon, based on the Emean value obtained by SWE, can be helpful in guiding clinicians to objectively examine the prognosis of patients.

Cervical Expanding Hematomas in Dogs: Five Cases

2002 ◽  
Vol 38 (6) ◽  
pp. 533-540 ◽  
Author(s):  
A. J. Deneuche ◽  
V. T. Viateau ◽  
L. Boulouha
Keyword(s):  
Histopathological Examination ◽  
Needle Aspiration ◽  
Surgical Removal ◽  
Coagulation Disorder ◽  
En Bloc ◽  
Chronic Expanding Hematoma ◽  
Coagulation Tests ◽  
Previous Trauma ◽  
Postoperative Drainage ◽  
Veterinary School

Five puppies were presented to the Alfort National Veterinary School for a rapidly expanding, well-demarcated, subcutaneous cervical mass of a few days’ duration. In all cases, previous trauma was reported. Fine-needle aspiration of the mass in each case revealed a serosanguineous fluid containing mainly erythrocytes, with a total protein concentration ranging from 3.5 to 5.2 g/dL. Coagulation tests failed to reveal any coagulation disorder. En-bloc surgical removal of the fluid-filled mass associated with short-term postoperative drainage was curative in all cases. Histopathological examination of the mass revealed encapsulated hematoma. The disease resembles chronic expanding hematoma in humans.

scholarly journals Feasibility of Using Shear Wave Elastography to Quantify Achilles Tendinopathy Stiffness Before and After Rehabilitation

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 337-338
Author(s):  
Robert A. Whitehurst ◽  
Shane L. Koppenhaver ◽  
Stephanie R. Albin ◽  
Matt T. Hartshorne ◽  
Darren W. Hearn ◽  
...  
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Achilles Tendinopathy ◽  
Before And After

scholarly journals Electrical Remodeling of Ventricular Repolarization Abnormality after Treatment in Pheochromocytoma: U Wave Finding in a Retrospective Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Giuseppe Di Stolfo ◽  
Sandra Mastroianno ◽  
Angela Maggio ◽  
Giovanni De Luca ◽  
Domenico R. Potenza ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Retrospective Analysis ◽  
Tumor Size ◽  
Systemic Blood Pressure ◽  
Ventricular Repolarization ◽  
P Wave ◽  
Surgical Removal ◽  
Pr Interval ◽  
Before And After ◽  
Qrs Duration

Background. Pheochromocytoma is a rare neuroendocrine tumor, clinically characterized by high blood pressure, palpitations, and headache. It is often associated with abnormalities of the ventricular repolarization phase; the dispersion of ventricular repolarization is the basis for ventricular arrhythmias (torsion de point, ventricular tachycardia or ventricular fibrillation). Objectives. Analysis of abnormal ventricular repolarization focused on the presence and amount of U wave in patients affected by pheochromocytoma and its modification after surgery. Materials and Methods. We reviewed pathology records of 722 patients admitted for adrenal nodule or suspected chromaffin-cell tumor and identified 39 patients affected by pheochromocytoma. Metanephrine, normetanephrine, and 3-methoxytyramine have been assessed by determining concentrations in 24-hour urine collection. Standard 12-lead electrocardiogram records have been reviewed with analysis of heart rate, P wave, PR interval, QRS duration, QTc, and U wave. Then we selected and compared 22 patients of 39 affected by pheochromocytoma, with both clinical and electrocardiographic data before and after surgery. Results. In our cohort of 39 patients affected by pheochromocytoma, we found U wave in ECG, before treatment, in 82.8 percent of patients, while only 37.0 percent after treatment (p<0.001) and we observed a statistically significant correlation between this wave and the urinary metanephrine. After surgery, in the selected 22 patients, we observed a clear significant reduction in systemic blood pressure, fasting glucose, metanephrine, normetanephrine, and 3-methoxytyramine. We found a significant reduction of U wave presence and leads involved in these patients after surgery (90.9% versus 9%). We observed a linear correlation between the amount of U waves in 12-lead electrocardiogram and metanephrine (r2=0.333, p=0.015), 3-methoxytyramine levels (r2=0.458, p=0.006), and tumor size (r2=0.429, p=0.003). Conclusions. In our retrospective analysis, patients affected by pheochromocytoma presented U wave in electrocardiogram. The presence and amount of U wave were associated with the metanephrine levels and the tumor size with significant reduction after surgical removal.

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