scholarly journals Swim Bladder Disorders in Koi Carp (Cyprinus carpio)

Animals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1974
Author(s):  
Rubina Sirri ◽  
Luciana Mandrioli ◽  
Samuele Zamparo ◽  
Francesca Errani ◽  
Enrico Volpe ◽  
...  
Keyword(s):  
Medical Intervention ◽  
Clinical Approach ◽  
Swim Bladder ◽  
Pharmacological Management ◽  
Koi Carp ◽  
Antimicrobial Susceptibility Pattern ◽  
Bladder Disorders ◽  
Fish Survival ◽  
Gross Examination

Swim bladder disorders and consequent buoyancy problems are encountered in ornamental fish, including koi carp. Nevertheless, beyond clinical and pharmacological management, they are largely underdiagnosed. In this study, nine koi carp showing abdominal swelling and abnormal swimming behavior were investigated. Clinical approach, varying from case to case, included ultrasonographic and X-ray investigations, bacteriological analysis of the collected fluid, antimicrobial susceptibility pattern, and possibly histological analysis. Diagnostic imaging, corroborating gross examination, documented swim bladder deformation/dislocation and serous fluid within the swim bladder chambers of most animals. Bacteria belonging to the Aeromonas hydrophila/caviae group and Shewanella xiamenensis were identified. S. xiamenensis strains showed a sensibility to all tested molecules except for one strain, which was resistant to tetracycline and cyprofloxacin. Antibiotic treatment succeeded in the full recovery of three cases in which S. xiamemensis infection was detected. Chronic aerocystitis was histologically documented where tissue was available. The swim bladder histopathological findings highlighted a chronic process that had compromised the quality of life of the animals. A multidisciplinary clinical–pathological and microbiological approach is highly suggested to recognize swim bladder conditions as early as possible, aiming to drive medical intervention and raising the chances of fish survival.

The Keloid Intervention Benefit Inventory 21: A New Assessment Tool for the Quality of Life of Patients with Auricular Keloids

2021 ◽  
Author(s):  
Daniel Häussler ◽  
Stefanie Hüttemann ◽  
Christel Weiß ◽  
Nicole Karoline Rotter ◽  
Haneen Sadick
Keyword(s):  
Quality Of Life ◽  
Internal Consistency ◽  
Social Impact ◽  
Assessment Tool ◽  
Clinical Symptoms ◽  
Physical Symptoms ◽  
Medical Intervention ◽  
Medical Interventions ◽  
Before And After

Abstract Purpose The assessment of the quality of life (QoL) of patients with chronic diseases before and after medical interventions has gained increasing importance in recent decades. Particularly for patients with visible keloid scars in the head and neck region, standardized measurement tools are either absent or have been shown to be insufficient. The aim of the present study was to create a new standardized questionnaire that is specific to auricular keloid patients and reflects their clinical symptoms and QoL. Methods The Keloid Intervention Benefit Inventory 21 (KIBI-21) questionnaire was developed in two stages. First, a group of experts identified a pool of 26 questions and modified and supplemented the items through a comparison with existing QoL assessments so that they related to keloid-specific clinical symptoms and the QoL of patients with auricular keloids before and after a medical intervention. This questionnaire was distributed to 27 outpatients who had undergone medical interventions for visible auricular keloids. Second, a sequential statistical analysis was conducted. This included a single-item assessment and reduction, analysis for internal consistency, construct validity, and divergence validity as well as a factor analysis. The analyses were performed for the entire questionnaire and for the items in the subcategories General Health, Physical Symptoms, Self-Esteem, and Social Impact. Results The final version of this newly validated and standardized KIBI questionnaire consisted of 21 items, of which each item was assigned to only one subscale. The questionnaire showed a Cronbach's α of 0.84 with a good internal consistency. In the item correlation validity, strong associations were found in all subscales, except for the Social Impact Subscale. Conclusion The keloid-specific QoL questionnaire KIBI-21 proved to be a reliable and reproducible instrument to assess the QoL and clinical symptoms in patients suffering from auricular keloids before and after a medical treatment.

scholarly journals Assessment of neuropsychiatric symptoms in dementia: Toward improving accuracy

2013 ◽  
Vol 7 (3) ◽  
pp. 244-251 ◽  
Author(s):  
Florindo Stella
Keyword(s):  
Rating Scale ◽  
High Reliability ◽  
Neuropsychiatric Symptoms ◽  
Clinical Approach ◽  
Behavioral Disturbances ◽  
Versatile Tool ◽  
Clinician Rating ◽  
Improving Accuracy ◽  
Elderly Caregivers

ABSTRACT The issue of this article concerned the discussion about tools frequently used tools for assessing neuropsychiatric symptoms of patients with dementia, particularly Alzheimer's disease. The aims were to discuss the main tools for evaluating behavioral disturbances, and particularly the accuracy of the Neuropsychiatric Inventory - Clinician Rating Scale (NPI-C). The clinical approach to and diagnosis of neuropsychiatric syndromes in dementia require suitable accuracy. Advances in the recognition and early accurate diagnosis of psychopathological symptoms help guide appropriate pharmacological and non-pharmacological interventions. In addition, recommended standardized and validated measurements contribute to both scientific research and clinical practice. Emotional distress, caregiver burden, and cognitive impairment often experienced by elderly caregivers, may affect the quality of caregiver reports. The clinician rating approach helps attenuate these misinterpretations. In this scenario, the NPI-C is a promising and versatile tool for assessing neuropsychiatric syndromes in dementia, offering good accuracy and high reliability, mainly based on the diagnostic impression of the clinician. This tool can provide both strategies: a comprehensive assessment of neuropsychiatric symptoms in dementia or the investigation of specific psychopathological syndromes such as agitation, depression, anxiety, apathy, sleep disorders, and aberrant motor disorders, among others.

scholarly journals The Severity of Fatigue Among Bone Marrow Transplantation Patients

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 99s-99s
Author(s):  
O. Abdalrahman ◽  
E. Almashaikh ◽  
H. Aljarrah
Keyword(s):  
Quality Of Life ◽  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Cancer Patients ◽  
Subscale Score ◽  
Medical Intervention ◽  
Significant Difference ◽  
Fatigue Severity ◽  
Male Patients

Background: Fatigue interferes with the individual´s functioning and quality of life in cancer patients specifically, after chemotherapy and post–bone marrow transplantation (BMT), fatigue is not adequately addressed and prioritized among health care providers. Aim: The purpose of this study is to determine the severity and prevalence of fatigue among cancer patients post-BMT after receiving chemotherapy. Methods: A descriptive, cross-sectional and correlational design was used, Piper fatigue scale (PFS) Arabic version was used to measure participants' level of fatigue, the scale measures four dimensions of subjective fatigue: behavioral, affective, sensory, and cognitive. Patients above 18 years old, received chemotherapy and do BMT between Oct 2016 and Oct 2017, were included in this study. Results: 100 patient participated in this study, 52% (N: 52) diagnosed with leukemia, 32% (N: 32) lymphoma, and 16% (N: 16) hematology. Thirty-nine patients (39%) had no or mild fatigue level, they do not need medical intervention, 47% (N: 47) and 14% (N: 14) classified as moderate and sever level of fatigue respectively, equal to 61% of the total sample who need medical intervention. Overall fatigue severity categories; mild, moderate, and sever shows that there is significant difference in term of severity subscale in sensory and behavioral dimensions ( P = 0.03, 0.004) respectively, and the other subscale dimension did not significantly differ among patient ( P > 0.05), the highest mean subscale score occurred in the behavioral dimension (M = 4.8, SD = 2.37), while the lowest mean subscale score occurred in cognitive dimension, (M=2.59, SD=2.35). The overall score mean of the male patients regarding the fatigue severity was 45.18 (n=74), and for the female patients the mean was 57.03 (n=26), and the result shows that there was significant difference in the overall mean scores between male patients and female patients (t (98)= −2.2, P < 0.05). Conclusion: Fatigue-related to BMT is a serious and prevalent problem among patients with cancer. Fatigue may impair quality of life among this group of patients; further study may be conducted to assess the effect of fatigue on quality of life and activity of daily living. It is essential to include fatigue assessment as a priority for the BMT patients.

scholarly journals Prevalence and impact of allergic rhinitis in school going children

2021 ◽  
Vol 7 (5) ◽  
pp. 760
Author(s):  
Sucheta Gupta ◽  
Vinod Gupta ◽  
Akhil Gupta
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Negative Impact ◽  
Community Health Center ◽  
Medical Intervention ◽  
House Dust Mites ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Co Morbidity

<p><strong>Background:</strong> Allergic rhinitis (AR) is a chronic inflammatory disorder affecting the nasal mucosa. There is negative impact of AR on several aspects of day to day living and quality of life (QoL), which include: daily functioning, sleep, absenteeism, school productivity and academic performance. Almost 40% of children are being affected by AR.</p><p><strong>Method:</strong> An observational study was conducted on randomly selected 100 parents of school going children aging 2 to 15 years, attending OPD in community health center, Chenani, district Udhampur, J and K, for a period of one year from June 2018 to Nov 2018. Children having frequent episodes of allergic rhinitis were enquired about their history of sneezing, runner itchy nose and eyes, thick mucus, nasal blockage or breathless with associated symptoms were selected.</p><p><strong>Results:</strong> 81% of subjects had a worse problem during specific months of the year; and 67% had itchy-watery eyes. In 15% of subjects, AR impacted daily activities. A prevalence of 28% for nasal symptoms and 14% for allergic rhino-conjunctivitis was found. Study also showed significantly higher proportion of blockers (61%) than sneeze runners (39%). 56% children had one or more co morbidity, whereas 44% had ‘nil’ co-morbidities. The most common allergens were: pollens (grass, trees and weeds), house dust mites, pets, molds, fungi and food.</p><p><strong>Conclusions:</strong> AR adversely affects quality of life of patients and furthermore studies should be conducted for more clarity on the subject, besides a timely medical intervention and treatment could possibly avoid the rising morbidity associated with the disease.</p>

Applying Social Aspects in Home Telecare Design to Improve the Safety of Users and Quality of Service

2016 ◽  
pp. 1048-1072
Author(s):  
Lawrence Chidzambwa
Keyword(s):  
Quality Of Life ◽  
Patient Safety ◽  
Life Quality ◽  
Cost Effective ◽  
Medical Intervention ◽  
Social Dimension ◽  
Social Aspects ◽  
The Social ◽  
Solution Design

Telecare enables remote and cost-effective home treatment of patients, improving the safety and quality of life of frail individuals. However, despite increased availability of telecare devices, many are not fully used and often ignored due to poor social perception and experience. The research suggests the social aspects of quality and safety related to user experience have not been considered. This can lead to misuse or non-use of telecare devices, reducing patient safety and quality of life. This chapter explores the implications for the lack of social considerations in telecare and develops a series of models and methodologies to integrate the social dimension with the traditional medical intervention focus. By applying semiotics and normative behavioural theory, the authors show how a Normative Home Telecare Framework can improve telecare solution design and ensure take up and use of the devices and increase patient safety and life quality.

Urgent Syndromes at the End of Life

2019 ◽  
pp. 344-355
Author(s):  
Quinten Robertson ◽  
Kelli Gershon
Keyword(s):  
End Of Life ◽  
Superior Vena ◽  
Life Stage ◽  
Vena Cava ◽  
Cord Compression ◽  
Medical Intervention ◽  
Her Family ◽  
Disease Trajectory ◽  
Appropriate Education

During the end-of-life stage, patients can experience a variety of urgent syndromes that can be treated effectively to reduce pain and improve quality of life. Conditions such as superior vena cava obstruction, pleural effusion, hemoptysis, spinal cord compression, hypercalcemia, and pathological fractures often result from progression across the disease trajectory and are particularly common among patients with advanced cancers. Nursing and medical caregivers must be familiar with these conditions, recognize them when they occur, and provide appropriate education and support for the patient and his or her family in addition to effective medical intervention. Awareness of urgent syndromes that may occur at end of life can help caregivers to provide more effectual palliative care that diminishes distress and suffering for the patient and their family.

scholarly journals Matching with Text Data: An Experimental Evaluation of Methods for Matching Documents and of Measuring Match Quality

2020 ◽  
Vol 28 (4) ◽  
pp. 445-468 ◽  
Author(s):  
Reagan Mozer ◽  
Luke Miratrix ◽  
Aaron Russell Kaufman ◽  
L. Jason Anastasopoulos
Keyword(s):  
Propensity Scores ◽  
Human Subjects ◽  
Medical Intervention ◽  
Exact Matching ◽  
Match Quality ◽  
Text Documents ◽  
Text Data ◽  
News Sources ◽  
Text Matching

Matching for causal inference is a well-studied problem, but standard methods fail when the units to match are text documents: the high-dimensional and rich nature of the data renders exact matching infeasible, causes propensity scores to produce incomparable matches, and makes assessing match quality difficult. In this paper, we characterize a framework for matching text documents that decomposes existing methods into (1) the choice of text representation and (2) the choice of distance metric. We investigate how different choices within this framework affect both the quantity and quality of matches identified through a systematic multifactor evaluation experiment using human subjects. Altogether, we evaluate over 100 unique text-matching methods along with 5 comparison methods taken from the literature. Our experimental results identify methods that generate matches with higher subjective match quality than current state-of-the-art techniques. We enhance the precision of these results by developing a predictive model to estimate the match quality of pairs of text documents as a function of our various distance scores. This model, which we find successfully mimics human judgment, also allows for approximate and unsupervised evaluation of new procedures in our context. We then employ the identified best method to illustrate the utility of text matching in two applications. First, we engage with a substantive debate in the study of media bias by using text matching to control for topic selection when comparing news articles from thirteen news sources. We then show how conditioning on text data leads to more precise causal inferences in an observational study examining the effects of a medical intervention.

scholarly journals How to evaluate Quality of Life

2019 ◽  
Vol 89 (1) ◽  
Author(s):  
Silvia Porcu ◽  
Antonella Mandas
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Technological Progress ◽  
Objective Evaluation ◽  
Medical Intervention ◽  
Social Health ◽  
Clinical Parameters ◽  
Medical Terminology ◽  
High Prevalence

In medical terminology, it has become more and more common the use of the expression “Quality of Life” (QoL) to define a series of aspects that go beyond the traditional, clinical and “objective” evaluation of the medical intervention. The attention to QoL comes from the need to find tools that are able to reveal important aspects of the life of the patient that cannot be measured by a laboratory exam and/or a radiological procedure. The QoL is measured through multidimensional questionnaires on, at the very least, the domains of physical, psychological and social health. The improvement of the health care standards and the technological progress in medical matters have brought about an increase in the average age of the population, and as a consequence, an increase of the chronic and degenerative disease, which can negatively influence the patient’s quality of life. Amongst these pathologies, heart failure (HF) has a high prevalence in patients who are at least 70 years old, and it’s the cause of frequent and repeated hospitalizations. The estimate of the QoL becomes then a very important piece of the puzzle to figure out, as important as the clinical parameters, to allow the patient to become an integral part of the physician’s decisions and to reach more quickly and with better results the therapeutic objectives.

scholarly journals Sacroiliac Pain: A Clinical Approach for the Neurosurgeon

2017 ◽  
Vol 08 (04) ◽  
pp. 622-627 ◽  
Author(s):  
Luis Rafael Moscote-Salazar ◽  
Hernando Raphael Alvis-Miranda ◽  
Andrei Fernandes Joaquim ◽  
Jessica Amaya-Quintero ◽  
Huber S. Padilla-Zambrano ◽  
...  
Keyword(s):  
Public Health Problem ◽  
Diagnostic Techniques ◽  
Unknown Etiology ◽  
Clinical Approach ◽  
Clinical Criteria ◽  
Positive Data ◽  
Health Related ◽  
Important Amount ◽  
Rule Out

ABSTRACTPain originating from sacroiliac joint may also cause pain in the lumbar and gluteal region in 15% of the population. The clinical manifestation represents a public health problem due to the great implications on the quality of life and health-related costs. However, this is a diagnosis that is usually ignored in the general clinical practice; probably because of the unknown etiology, making harder to rule out the potential etiologies of this pathology, or maybe because the clinical criteria that support this pathology are unknown. By describing several diagnostic techniques, many authors have studied the prevalence of this pathology, finding more positive data than expected; coming to the conclusion that even though there is no diagnostic gold standard yet, an important amount of cases might be detected by properly applying several tests at the physical examination. Thus, it is necessary to have knowledge of the physiopathology and clinical presentation so that diagnosis can be made to those patients that manifest this problem. We present a clinical approach for the neurosurgeon.

scholarly journals Podocyturia: What is in a name?

2015 ◽  
Vol 3 (2) ◽  
pp. 51-56 ◽  
Author(s):  
Hernán Trimarchi
Keyword(s):  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Outer Space ◽  
Clinical Approach ◽  
Metabolic Disturbances ◽  
Differentiated Cells ◽  
Surrounding Matrix ◽  
Normal Environment ◽  
New Situation

Abstract The podocyte is a highly differentiated cell located in the outer space of the glomerular basement membrane that deals with many different functions. This phylogenetically preserved cell that is responsible for the virtually absence of proteins in the urine lacks of the capacity to divide under normal conditions. When podocytes receive molecular insults, which normally occur during stress conditions as glomerulonephritis, hyperfiltration or metabolic disturbances, they adapt to the new situation by contracting their actin fibers. This adaptive behavior puts at risk the quality of the plasmatic filtration due to the denudation of the glomerular basement membrane, the potential mesangial inflammation and the appearance of proteinuria; podocytes run the risk of detachment from the basement membrane due to a decrease in the adherence to the surrounding matrix after contraction, a process called foot processes effacement. Podocytes change their shape and under constant mechanical stress they finally detach, rendering the glomerular basement membrane unprotected unless other contiguous podocytes are capable of covering the surface. However, these still anchored podocytes are generally also under the same stress situation and follow the same pathway. Podocyturia refers to the presence of these differentiated cells in the urinary sediment. Noteworthy, the podocytes that are encountered in the urine are viable despite the glomerular hostile environment and the urinary acidity. Podocyturia can precede proteinuria and can aggravate it. Therefore, in diseases that can threaten the glomerular normal environment, the presence and the quantification of urinary podocytes can be of remarkable relevance, as it can herald or accompany the appearance of proteinuria, and could offer another view to the interpretation and clinical approach and outcome of proteinuria. However, its identification needs a wide-spread training among biochemists and technicians, as well as commercially available kits.

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