scholarly journals Urinalysis in Great Dane Puppies from Birth to 28 Days of Age

Animals ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 636 ◽  
Author(s):  
Monica Melandri ◽  
Maria Cristina Veronesi ◽  
Salvatore Alonge
Keyword(s):  
Specific Gravity ◽  
Neonatal Period ◽  
Clinical Tool ◽  
First Line ◽  
Dipstick Test ◽  
Non Invasive ◽  
Age Related ◽  
Concentrate Urine ◽  
Dipstick Urinalysis ◽  
Age Related Changes

Urinalysis, a common test in infants, could represent a suitable non-invasive clinical tool in puppies. In dog neonates, urine is easily collected by stimulating the somato-vesccal reflex. Information on urine characteristics during the neonatal period is missing. Beside instrumental laboratory analyses, the dipstick was proven useful for rapid urinalysis to evaluate specific gravity (SG), pH, leukocytes, nitrites, glucose, proteins, ketones, urobilinogen, bilirubin, and blood. The present study aimed to describe urinalysis features by the dipstick test and refractometer along the neonatal period. Urine samples (n = 624) were collected by manual stimulation from 48 healthy Great Danes, daily from birth to seven days, then twice a week until 28 days, to assess age-related changes (ANOVA, p < 0.05) and the possible effects of gender and litter (T-test, p < 0.05). The SG and pH significantly changed during the neonatal period. Other parameters did not vary significantly in relation to age. No significant differences were observed either among litters or between genders. The present study confirmed that canine kidneys are able to concentrate urine from the second week of age when the urinary SG started to be similar to adults, while pH still increased towards the typical values of adults at 28 days. Significant glucosuria and proteinuria were never detected. Dipstick urinalysis represents a useful first-line complementary tool in newborns clinical examination, providing information about systemic homeostasis.

Presbyacusis and the Auditory Brainstem Response

2002 ◽  
Vol 45 (6) ◽  
pp. 1249-1261 ◽  
Author(s):  
Flint A. Boettcher
Keyword(s):  
Hearing Loss ◽  
Auditory System ◽  
Auditory Brainstem Response ◽  
Animal Studies ◽  
Auditory Brainstem ◽  
Clinical Tool ◽  
Age Related ◽  
Brainstem Response ◽  
Auditory Functions ◽  
Age Related Changes

Age-related hearing loss (ARHL or presbyacusis) is an increasingly common form of sensorineural hearing loss (SNHL) as a result of changing demographics, and the auditory brainstem response (ABR) is a common experimental and clinical tool in audiology and neurology. Some of the changes that occur in the aging auditory system may significantly influence the interpretation of the ABR in comparison to the ABRs of younger adults. The approach of this review will be to integrate physiological and histopathological data from human and animal studies to provide a better understanding of the array of age-related changes in the ABR and to determine how age-related changes in the auditory system may influence how the ABR should be interpreted in presbyacusis. Data will be described in terms of thresholds, latencies, and amplitudes, as well as more complex auditory functions such as masking and temporal processing. Included in the review of data will be an attempt to differentiate between age-related effects that may strictly be due to threshold elevation from those that may be due to the aging process.

Non-invasive assessment of the age related changes in stiffness of major branches of the human arteries

1987 ◽  
Vol 21 (9) ◽  
pp. 678-687 ◽  
Author(s):  
T. KAWASAKI ◽  
S. SASAYAMA ◽  
S.-I. YAGI ◽  
T. ASAKAWA ◽  
T. HIRAI
Keyword(s):  
Non Invasive ◽  
Age Related ◽  
Human Arteries ◽  
Age Related Changes

Echocardiographic Findings and Cardiovascular Profile of the Very Old Indian Population

2020 ◽  
Vol 16 (2) ◽  
Author(s):  
Pramod Kumara ◽  
Rishav Bansal ◽  
Rakesh Yadav ◽  
Sada Nand Dwivedi ◽  
Prashun Chatterjee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Cardiovascular Diseases ◽  
Very Old ◽  
Old Adults ◽  
Non Invasive ◽  
Age Related ◽  
Echocardiographic Assessment ◽  
Age Related Changes

Background : Age-related changes in the cardiovascular system are significant, increasing the risk of cardiovascular diseases (CVDs) in older adults. CVDs are currently the leading cause of mortality among older Indian adults, yet very few studies are presently available evaluating the older adults for CVDs and risk factors. We aim to assess the very old adults for the prevalence of CVDs and risk factors using non-invasive assessment tools. Methodology : This hospital-based cross-sectional study included 200 adults aged 75 years and above, visiting a tertiary care hospital in India. They underwent routine clinical evaluation, a comprehensive geriatric assessment and detailed cardiovascular evaluation using non-invasive tools like echocardiography and blood investigations. Results : The overall prevalence of CVDs in this population was 76%. Among the cardiovascular risk factors, hyperhomocysteinemia was present in 83.5%, hypertension in 59.5%, dyslipidemia in 41.5%, sedentary lifestyle in 35%, and obesity in 30.5%, and Diabetes Mellitus in 24.5%. In echocardiographic assessment, valvular dysfunction was present in 33% of the population, though moderate to severe valvular disease was seen in 6.5%. Left ventricular diastolic dysfunction was seen in 81%, systolic dysfunction in 10% and pulmonary hypertension in 5% of the subjects. Conclusion : The very old adults had significant age-related changes in echocardiographic assessment, along with the high prevalence of cardiovascular diseases and risk factors. These findings should encourage physicians to screen the very old adults for cardiovascular risk factors and diseases, for their early identification and effective management.

Experience in applying new methodological approach to photodynamic therapy in cosmetology

2019 ◽  
Vol 2 (26) ◽  
pp. 25-28
Author(s):  
N. V. Bochkova ◽  
L. S. Kholupova ◽  
D. O. Yurchenko
Keyword(s):  
Photodynamic Therapy ◽  
Methodological Approach ◽  
Non Invasive ◽  
Age Related ◽  
Scientific Justification ◽  
Aesthetic Results ◽  
Aging Mechanisms ◽  
Internal And External Factors ◽  
Active Substances ◽  
Age Related Changes

Age-related changes in the skin are combined and are associated with both internal and external factors. The study of aging mechanisms contributes to the development and scientific justification of the application of various methods of correction of involutive changes. A special place is occupied by the development of non-invasive methods of exposure, as well as their combination to achieve the best result and increase safety. Electroporation is actively used in cosmetology for the introduction of various active substances into the epidermis and, in some cases, into the dermis. The use of this method in combination with photodynamic therapy allows to achieve excellent aesthetic results and increases patient compliance.

scholarly journals Aged neutrophils contribute to the first line of defense in the acute inflammatory response

Blood ◽  
2016 ◽  
Vol 128 (19) ◽  
pp. 2327-2337 ◽  
Author(s):  
Bernd Uhl ◽  
Yannick Vadlau ◽  
Gabriele Zuchtriegel ◽  
Katharina Nekolla ◽  
Kariem Sharaf ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
First Responders ◽  
Acute Inflammatory Response ◽  
First Line ◽  
Inflammatory Reactions ◽  
Age Related ◽  
Key Points ◽  
Age Related Changes

Key Points Aged neutrophils exhibit a distinct, highly reactive phenotype that depends on age-related changes in their molecular repertoire. This specific phenotype of aged neutrophils enables them to serve as “first responders” in inflammatory reactions.

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