scholarly journals Effects of Dietary Supplementation with Combination of Tributyrin and Essential Oil on Gut Health and Microbiota of Weaned Piglets

Animals ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 180 ◽  
Author(s):  
Wen-Xin Zhang ◽  
Yu Zhang ◽  
Xiao-Wei Zhang ◽  
Zhao-Xi Deng ◽  
Jian-Xin Liu ◽  
...  
Keyword(s):  
Methyl Salicylate ◽  
Animal Health ◽  
Morphological Structure ◽  
Basal Diet ◽  
Gut Health ◽  
Feed Conversion ◽  
Weaned Piglets ◽  
Villus Height ◽  
Large White ◽  
The Difference

The aim of this study was to determine the effects of dietary inclusion of the combination of tributyrin with oregano or methyl salicylate as a substitute to antibiotics on gut health and microbiota of piglets. A total of 48 weaned crossbred piglets (Duroc × Large White × Landrace, 8.79 ± 0.97 kg, 21 ± 1 d) were randomly allocated to four experimental groups and fed for 4 weeks: the basal diet (Con); the control plus antibiotics (AB); the control plus oregano and tributyrin (OT); and the control plus methyl salicylate and tributyrin (MT). Although a numerical improvement on feed intake, weight gain and feed conversion ratio was observed in the OT and MT as well as the AB group, the difference was not significant (p > 0.05). The OT and MT groups were larger in villus height in the duodenum compared to the Con (p < 0.05), and were larger in relative abundance of Firmicutes/Bacaeroides in the intestine compared to Con and AB groups (p < 0.01). The amount of major different metabolites was 6, 8 and 8 for the AB, OT and MT groups when compared to the Con, respectively. In conclusion, as a substitute for antibiotics the inclusion of the combination of tributyrin with either oregano or methyl salicylate to the diet of weaned piglets improved the intestinal morphological structure and altered intestinal microbiota and metabolites, which were beneficial to the animal health.

scholarly journals Administration of Saccharomyces boulardii mafic-1701 improves feed conversion ratio, promotes antioxidant capacity, alleviates intestinal inflammation and modulates gut microbiota in weaned piglets

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wenxiu Zhang ◽  
Chengling Bao ◽  
Jian Wang ◽  
Jianjun Zang ◽  
Yunhe Cao
Keyword(s):  
Intestinal Inflammation ◽  
Animal Health ◽  
Dietary Treatment ◽  
Basal Diet ◽  
Saccharomyces Boulardii ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Feed Conversion ◽  
Weaned Piglets ◽  
Treatment Groups

Abstract Background Probiotics are used as a means to improve animal health and intestinal development. Saccharomyces boulardii is a well-known probiotic; however, few studies have examined the effects of S. boulardii on weaned piglet performance. Therefore, this 28-day study compared the effects of S. boulardii mafic-1701 and aureomycin in diets for weaned piglets on growth performance, antioxidant parameters, inflammation and intestinal microbiota. One hundred and eight piglets, weaned at 28 d of age (8.5 ± 1.1 kg), were randomly divided into the three dietary treatment groups with six pens and six piglets per pen (half male and half female). The dietary treatment groups were as follows: 1) basal diet (CON); 2) basal diet supplemented with 75 mg/kg aureomycin (ANT); 3) basal diet supplemented with 1 × 108 CFU/kg S. boulardii mafic-1701 (SB). Results Compared to CON group, SB group had higher feed efficiency (P < 0.05) in the last 14 d and lower diarrhea rate (P <  0.05) over the entire 28 d. Total superoxide dismutase in serum was markedly increased in SB group (P < 0.05). Moreover, compared with CON group, SB group decreased the levels of pro-inflammatory cytokines interleukin-6 (P <  0.01) and Tumor necrosis factor-α (P < 0.05) in jejunum. Supplementation of S. boulardii mafic-1701 increased the abundance of Ruminococcaceae_UCG_009 and Turicibacter (P < 0.05), whereas the abundance of unclassified_Clostridiaceae_4 was decreased (P < 0.05). Furthermore, S. boulardii mafic-1701 administration increased cecal concentration of microbial metabolites, isobutyrate and valerate (P < 0.05). Conclusions The improvement in feed conversion ratio, reduction in diarrhea rate in weaned piglets provided diets supplemented with S. boulardii mafic-1701 may be associated with enhanced antioxidant activity, anti-inflammatory responses and improved intestinal microbial ecology.

scholarly journals Dietary Supplementation With Bacillus subtilis Promotes Growth and Gut Health of Weaned Piglets

2021 ◽  
Vol 7 ◽  
Author(s):  
Zhilong Tian ◽  
Xiaodan Wang ◽  
Yehui Duan ◽  
Yue Zhao ◽  
Wenming Zhang ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Intestinal Morphology ◽  
Control Group ◽  
Gut Health ◽  
Weaned Piglets ◽  
Villus Height ◽  
Expression Of Genes ◽  
Group A

This study was conducted to investigate the effects of dietary supplementation with different types of Bacillus subtilis (B. subtilis) on the growth and gut health of weaned piglets. A total of 160 piglets were randomly assigned into four groups: control group (a basal diet), BS-A group (a basal diet supplemented with B. subtilis A at 1 × 106 CFU/g feed), BS-B group (a basal diet supplemented with B. subtilis B at 1 × 106 CFU/g feed), and BS-C group (a basal diet supplemented with B. subtilis C at 1 × 106 CFU/g feed). All groups had five replicates with eight piglets per replicate. On days 7, 21, and 42 of the trial, blood plasma and intestinal tissues and digesta samples were collected to determine plasma cytokine concentrations, intestinal morphology, gut microbiota community and metabolic activity, and the expression of genes related to gut physiology and metabolism. The results showed that dietary B. subtilis supplementation improved (P &lt; 0.05) the body weight and average daily gain (in BS-B and BS-C groups) of weaned piglets and decreased (P &lt; 0.05) the diarrhea rates (in BS-A, BS-B, and BS-C groups). In the intestinal morphology analysis, B. subtilis supplementation improved (P &lt; 0.05) the size of villus height and villus height to crypt depth ratio in the ileum of weaned piglets. Firmicutes, Bacteroidetes, and Tenericutes were the most dominant microflora in piglets' colon whatever the trial group and time of analysis. Dietary BS-C supplementation increased (P &lt; 0.05) the relative abundances of Anaerovibrio and Bulleidia and decreased (P &lt; 0.05) the relative abundances of Clostridium and Coprococcus compared with the control group. In addition, dietary B. subtilis supplementation increased (P &lt; 0.05) the indicators of intestinal health, including plasma levels of interleukin (IL)-2 and IL-10, as well as the colonic levels of short-chain fatty acids. Furthermore, dietary B. subtilis supplementation also up-regulated (P &lt; 0.05) the expression of genes involved in metabolic pathways related to intestinal microbiota maturation. In conclusion, these findings suggest that a diet containing BS-B or BS-C can efficiently promote growth performance, decrease diarrhea incidence, and ameliorate several indicators of intestinal health through the modulation of gut microbiota composition and metabolic activity in weaned piglets.

scholarly journals Administration of Saccharomyces boulardii mafic-1701 improves feed conversion ratio, promotes antioxidant capacity, alleviates intestinal inflammation and modulates gut microbiota in weaned piglets

2020 ◽  
Author(s):  
Wenxiu Zhang ◽  
Chengling Bao ◽  
Jian Wang ◽  
Jianjun Zang ◽  
Yunhe Cao
Keyword(s):  
Intestinal Inflammation ◽  
Inflammatory Responses ◽  
Animal Health ◽  
Basal Diet ◽  
Saccharomyces Boulardii ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Feed Conversion ◽  
Weaned Piglets ◽  
Weaned Piglet

Abstract Background: Probiotics for are used as a means to improve animal health and intestinal development. Saccharomyces boulardii (S. boulardii) is a well-known probiotic, however, few studies have examined the effects of S. boulardii on weaned piglet performance. Therefore, this 28-day study compared the effects of S. boulardii mafic-1701 and aureomycin in weaned piglet diets on growth performance, antioxidant parameters, inflammation and intestinal microbiota. One hundred and eight weaned piglets were randomly divided into three dietary treatment groups: (1) basal diet (CON); (2) basal diet supplemented with 75 mg/kg aureomycin (ANT); (3) basal diet supplemented with 1 × 108 CFU/kg S. boulardii mafic-1701 (SB). Results: Compared to CON group, SB group improved feed efficiency over the entire 28 days (P < 0.01) and decreased the rate of diarrhea during the first two weeks (P < 0.05). Total superoxide dismutase concentration was markedly increased in SB group (P < 0.05). Moreover, compared with CON group, SB group decreased the level of pro-inflammatory cytokines interleukin-6 (P < 0.01) and tumor necrosis factor (P < 0.05) in jejunum. Supplementation with S boulardii mafic-1701 increased abundance of Bacillus and Ruminococcaceae (P < 0.05), whereas abundance of Clostridiaceae was decreased (P < 0.05). Furthermore, S boulardii mafic-1701 administration increased cecal concentration of microbial metabolites, isobutyrate and valerate (P < 0.05). Conclusion: The improvement in feed conversion ratio, reduction in diarrhea rate during the first two weeks in weaned piglets provided diets supplemented with S. boulardii mafic-1701 may be associated with enhanced antioxidant activity, anti-inflammatory responses and intestinal microbial ecology.

scholarly journals Administration of Saccharomyces boulardii mafic-1701 improves feed conversion ratio, promotes antioxidant capacity, alleviates intestinal inflammation and modulates gut microbiota in weaned piglets

2020 ◽  
Author(s):  
Wenxiu Zhang ◽  
Chengling Bao ◽  
Jian Wang ◽  
Jianjun Zang ◽  
Yunhe Cao
Keyword(s):  
Intestinal Inflammation ◽  
Inflammatory Responses ◽  
Animal Health ◽  
Dietary Treatment ◽  
Basal Diet ◽  
Saccharomyces Boulardii ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Feed Conversion ◽  
Weaned Piglets

Abstract Background: Probiotics are used as a means to improve animal health and intestinal development. Saccharomyces boulardii ( S. boulardii ) is a well-known probiotic, however, few studies have examined the effects of S. boulardii on weaned pig let performance. Therefore, this 28-day study compared the effects of S. boulardii mafic-1701 and aureomycin in weaned piglet diets on growth performance, antioxidant parameters, inflammation and intestinal microbiota. One hundred and eight weaned piglets were randomly divided into three dietary treatment groups: (1) basal diet (CON); (2) basal diet supplemented with 75 mg/kg aureomycin (ANT); (3) basal diet supplemented with 1 × 10 8 CFU/kg S. boulardii mafic-1701 (SB). Results: Compared to CON group, SB group had higher feed efficiency ( P < 0.01) and lower diarrhea rate ( P < 0.05) over the entire 28 days. Total superoxide dismutase concentration in serum was markedly increased in SB group ( P < 0.05). Moreover, compared with CON group, SB group decreased the level of pro-inflammatory cytokines interleukin-6 ( P < 0.01) and tumor necrosis factor ( P < 0.05) in jejunum. Supplementation with S. boulardii mafic-1701 increased abundance of Bacillus and Ruminococcaceae_UCG_009 ( P < 0.05), whereas abundance of unclassified _Clostridiaceae_4 was decreased ( P < 0.05). Furthermore, S. boulardii mafic-1701 administration increased cecal concentration of microbial metabolites , isobutyrate and valerate ( P < 0.05). Conclusions: The improvement in feed conversion ratio, reduction in diarrhea rate in weaned piglets provided diets supplemented with S. boulardii mafic-1701 may be associated with enhanced antioxidant activity, anti-inflammatory responses and improved intestinal microbial ecology.

Effects of dietary probiotics on growth performance, faecal microbiota and serum profiles in weaned piglets

2014 ◽  
Vol 54 (5) ◽  
pp. 616 ◽  
Author(s):  
Xiaoli Dong ◽  
Naifeng Zhang ◽  
Meng Zhou ◽  
Yan Tu ◽  
Kaidong Deng ◽  
...  
Keyword(s):  
Growth Performance ◽  
Early Stage ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Feed Conversion ◽  
Faecal Microbiota ◽  
Weaned Piglets ◽  
Serum Globulin ◽  
Large White ◽  
E Coli

This study was conducted to evaluate the effects of dietary supplementation with probiotics on growth performance, faecal microbiota, and serum profiles in weaned piglets. Large White × Landrace piglets (n = 144) weaned at 35–37 days of age were selected and divided into four groups, and the piglets from each group were assigned randomly to six pens (replicates) with six animals each. Each group was fed one of four diets for 5 weeks: a basal diet without antibiotics and probiotics (control), or the basal diet supplemented with Lactobacillus plantarum GF103, Bacillus subtilis B27, or a mixture of L. plantarum GF103 and B. subtilis B27. During the first 2 weeks of the supplementation, the piglets supplemented with probiotics had lower (P < 0.05) average daily feed intake than control piglets. The feed conversion ratio was improved (P < 0.05) in probiotic-supplemented groups compared with that of control. The population of E. coli in faeces of the piglets supplemented with L. plantarum GF103 was lower (P < 0.05) than that of control piglets. On day 14, dietary supplementation of the combination of L. plantarum GF103 and B. subtilis B27 increased (P < 0.05) the serum concentrations of total protein, globulin, and creatinine, but decreased (P < 0.05) the ratio of serum albumin to serum globulin, compared with the basal diet. On day 14, dietary supplementation with probiotics increased (P < 0.05) the serum IgM concentration compared with the basal diet. Supplementation of B. subtilis B27 or the combination of L. plantarum GF103 and B. subtilis B27 increased (P < 0.05) the serum IgA concentration at the end of the trial. These results suggest that dietary probiotics improved growth performance and enhanced immune responses at the early stage of the post-weaning period in piglets.

scholarly journals Administration of Saccharomyces boulardii mafic-1701 improves feed conversion ratio, promotes antioxidant capacity, alleviates intestinal inflammation and modulates gut microbiota in weaned piglets

2020 ◽  
Author(s):  
Wenxiu Zhang ◽  
Chengling Bao ◽  
Jian Wang ◽  
Jianjun Zang ◽  
Yunhe Cao
Keyword(s):  
Intestinal Inflammation ◽  
Animal Health ◽  
Dietary Treatment ◽  
Basal Diet ◽  
Saccharomyces Boulardii ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Feed Conversion ◽  
Weaned Piglets ◽  
Treatment Groups

Abstract Background: Probiotics are used as a means to improve animal health and intestinal development. Saccharomyces boulardii is a well-known probiotic; however, few studies have examined the effects of S. boulardii on weaned piglet performance. Therefore, this 28-day study compared the effects of S. boulardii mafic-1701 and aureomycin in diets for weaned piglets on growth performance, antioxidant parameters, inflammation and intestinal microbiota. One hundred and eight piglets, weaned at 28 d of age (8.5 ± 1.1 kg), were randomly divided into the three dietary treatment groups with six pens and six piglets per pen (half male and half female). The dietary treatment groups were as follows: (1) basal diet (CON); (2) basal diet supplemented with 75 mg/kg aureomycin (ANT); (3) basal diet supplemented with 1 × 108 CFU/kg S. boulardii mafic-1701 (SB).Results: Compared to CON group, SB group had higher feed efficiency (P < 0.05) in the last 14 days and lower diarrhea rate (P < 0.05) over the entire 28 days. Total superoxide dismutase in serum was markedly increased in SB group (P < 0.05). Moreover, compared with CON group, SB group decreased the levels of pro-inflammatory cytokines interleukin-6 (P < 0.01) and Tumor necrosis factor-α (P < 0.05) in jejunum. Supplementation of S. boulardii mafic-1701 increased the abundance of Ruminococcaceae_UCG_009 and Turicibacter (P < 0.05), whereas the abundance of unclassified_Clostridiaceae_4 was decreased (P < 0.05). Furthermore, S. boulardii mafic-1701 administration increased cecal concentration of microbial metabolites, isobutyrate and valerate (P < 0.05).Conclusions: The improvement in feed conversion ratio, reduction in diarrhea rate in weaned piglets provided diets supplemented with S. boulardii mafic-1701 may be associated with enhanced antioxidant activity, anti-inflammatory responses and improved intestinal microbial ecology.

scholarly journals Live Yeast or Live Yeast Combined with Zinc Oxide Enhanced Growth Performance, Antioxidative Capacity, Immunoglobulins and Gut Health in Nursery Pigs

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1626
Author(s):  
Shenfei Long ◽  
Tengfei He ◽  
Sung Woo Kim ◽  
Qinghui Shang ◽  
Tadele Kiros ◽  
...  
Keyword(s):  
Average Daily Gain ◽  
Basal Diet ◽  
Conversion Ratio ◽  
Gut Health ◽  
Total Volatile ◽  
Feed Conversion ◽  
Nursery Pigs ◽  
Serum Iga ◽  
Daily Gain ◽  
Live Yeast

This study aimed to investigate the effects of dietary LY or LY combined with ZnO supplementation on performance and gut health in nursery pigs. 192 Duroc × Landrace × Yorkshire piglets (weaned on d 32 of the age with 9.2 ± 1.7 kg BW) were allocated into four treatments with eight replicate pens, six piglets per pen. The treatments included a basal diet as control (CTR), an antibiotic plus ZnO diet (CTC-ZnO, basal diet + 75 mg/kg of chlortetracycline + ZnO (2000 mg/kg from d 1 to 14, 160 mg/kg from d 15 to 28)), a LY diet (LY, basal diet + 2 g/kg LY), and a LY plus ZnO diet (LY-ZnO, basal diet + 1 g/kg LY + ZnO). The results showed that pigs fed LY or LY-ZnO had increased (p < 0.05) average daily gain, serum IgA, IgG, superoxide dismutase, fecal butyric acid, and total volatile fatty acid concentrations, as well as decreased (p < 0.05) feed conversion ratio and diarrhea rate compared with CTR. In conclusion, pigs fed diets with LY or LY combined with ZnO had similar improvement to the use of antibiotics and ZnO in performance, antioxidant status, immunoglobulins, and gut health in nursery pigs.

scholarly journals PSVIII-18 Dietary supplementation with trihexanoin enhances intestinal function of weaned piglets

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 302-303
Author(s):  
Tao Wu
Keyword(s):  
Fat Metabolism ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Intestinal Morphology ◽  
Mucosal Barrier ◽  
Mrna Levels ◽  
Intestinal Function ◽  
Weaned Piglets ◽  
Villus Height ◽  
And Function

Abstract Trihexanoin is a short-chain triglyceride (SCT). Many studies have reported that SCTs play important roles in the maintenance of intestinal epithelial structure and function. The present work was to investigate the effects of trihexanoin on growth performance, carbohydrate and fat metabolism, as well as intestinal morphology and function in weaned piglets. Twenty weaned piglets (21 ± 2 d) were randomly allocated to one of two treatment groups: the control group (basal diet supplemented with 0.5% soya oil); the TH group (basal diet supplemented with 0.5% trihexanoin). Dietary trihexanoin supplementation significantly reduced diarrhea rate (P &lt; 0.05); increased the concentrations of LDL, HDL and total protein, decreased cholesterol concentrations (CHOL) and glutamyl transpeptidase (GGT) activity in plasma (P &lt; 0.05); increased villus height, surface area, and the ratio of villus height to crypt depth (P &lt; 0.05); altered the mRNA levels and abundances of proteins related to glycogen and fat metabolism (gene LIPE, LPL, PPARG, ACACA, FASN, SLC27A2, INSR, PCK1 and ASS1), mucosal barrier function (protein claudin-1, and occludin), antioxidant capacity (protein HSP70 and gene Nrf2, NOX2 and GSTO2) and water transport capacity (protein AQP3 and gene AQP8 and AQP10) (P &lt; 0.05); altered the gene abundance of intestinal bacteria (Enterobacteriaceae, Enterococcus, Clostridium, Lactobacillus and Bifidobacterium) (P &lt; 0.05). In conclusion, dietary supplementation of trihexanoin improved the intestinal function and health of weaned piglets by regulating nutrient metabolism, improving intestinal function of mucosal barrier, transport, absorption and antioxidant, and altering the community of microbiota.

Further observations on the effects of growth checks in pigs of 50 lb. live-weight and over

1962 ◽  
Vol 4 (2) ◽  
pp. 195-202 ◽  
Author(s):  
I. A. M. Lucas ◽  
R. M. Livingstone ◽  
I. McDonald
Keyword(s):  
Live Weight ◽  
Carcass Composition ◽  
Sudden Increase ◽  
Feed Conversion ◽  
Severe Restriction ◽  
Minimum Thickness ◽  
Large White ◽  
Eye Muscle ◽  
The Difference ◽  
Gut Fill

Forty-eight individually-fed Large White pigs, initially 10 weeks of age, were used to test the effects of growth checks induced by severe restriction of feed intake. The checks were imposed at 50 lb. or 100 lb. live-weight and lasted for 5 weeks, during which live-weight gains averaged only 1·6 lb. and 4·1 lb. per pig, respectively. The daily feed allowances of the unchecked controls and of other pigs while not on check were according to a fixed scale based on live-weight. All pigs were slaughtered as their individual weights reached 200 lb. and a number of measurements were made on the carcasses.Excluding the period of the check, efficiency of feed conversion and rate of gain were better for pigs checked at 50 lb. than for the controls. The difference in age at a given weight caused by the check was narrowed by about 6 days at the end of the experiment. Indications of a similar compensation in growth of pigs checked at 100 lb. were mostly explained by the rapid growth of these pigs before 100 lb. and by the sudden increase i n their weight at the end of the check period which was probably due to increased gut fill.A check at 50 lb. or 100 lb. did not affect either the specific gravity of the carcass, which was taken as an indication of the overall proportion of lean to fat, the area of ‘eye’ muscle, the depth of backfat over the shoulder, the thickness of streak or the Danish ‘slight of lean’ measurement, but the check at 50 lb. increased the thickness of fat at position (1) over the ‘eye’ muscle. Both checks increased the minimum thickness of back fat in females but not in castrates and reduced the average rump fat in castrates but not in females. It was concluded that the checks did not affect carcass composition although they probably caused changes in the distribution of the backfat.

Effect of xylanase supplementation of wheat-based liquid diets, for weaner pigs, steeped for 1 or 24 h before feeding

2013 ◽  
Vol 53 (6) ◽  
pp. 540 ◽  
Author(s):  
Katie A. l'Anson ◽  
Mingan Choct ◽  
Peter H. Brooks
Keyword(s):  
Feed Intake ◽  
Control Diet ◽  
Basal Diet ◽  
Feed Conversion ◽  
Large White ◽  
Available Lysine ◽  
Daily Gain ◽  
Positive Effect ◽  
Weaner Pigs ◽  
Entire Male

Seventy-two individually housed, entire male (Large White × Landrace) weaner pigs (28 days; 7.4 ± 0.4 kg) were used in a 26-day feeding trial. The pigs were allocated to one of six treatments in a 3 by 2 factorial design. The factors were (1) steeping duration of liquid feed [0 (dry control diet), 1 or 24 h], and (2) enzyme supplementation (0 or 300 ppm xylanase). The basal diet was wheat-based (65%) and was formulated to be marginally adequate for pigs of this age, containing 14.5 MJ digestible energy (DE)/kg and 0.85 g available lysine/MJ DE. Feeding pigs liquid diets steeped for 1 h increased feed intake (61 g/day; s.e.d. 17; P < 0.05) and daily gain (70 g/day; s.e.d. 17; P < 0.05) and improved feed conversion ratio (1.16 versus 1.22; s.e.d. 0.03; P < 0.05) compared with pigs fed dry diets. Performance was not further improved by steeping for 24 h. The addition of xylanase to the diets had no positive effect on any of the performance measures and was associated with a significant (40 g/day; s.e.d. 14; P < 0.05) reduction in feed intake. These results provide no support for supplementing liquid diets for weaner pig diets with xylanase.

Sign in / Sign up

Export Citation Format

Share Document