scholarly journals Antimicrobial Activity and Spectral, Magnetic and Thermal Studies of Some Transition Metal Complexes of a Schiff Base Hydrazone Containing a Quinoline Moiety

Molecules ◽  
2007 ◽  
Vol 12 (5) ◽  
pp. 1080-1091 ◽  
Author(s):  
Nora Al-Sha’alan
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Quinoline Moiety

scholarly journals 1H NMR, Diffused Reflectance, Thermal Studies, ESR and Anti Microbial Activities of Schiff Base Derived from 5-Nitro Salicylaldehyde and p-Anisidine

2015 ◽  
Vol 48 ◽  
pp. 14-26
Author(s):  
Paresh S. More ◽  
Bipin H. Mehta
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Esr Spectroscopy ◽  
Thermal Studies ◽  
Microbial Activities ◽  
Tetrahedral Structure ◽  
H Nmr ◽  
Square Planar

Transition metal complexes of the type ML1 [Where M= Co(II),Ni(II),Cu(II) and Zn(II), L= Schiff base of 5 nitro-salicylaldehyde and p-anisidine were characterized by using 1H NMR, TGA, Diffused reflectance and ESR spectroscopy. On the basis of above studies Co(II), Ni(II) shows tetrahedral structure, Cu(II) and Zn(II) shows square planar structure.

scholarly journals Synthesis, Characterizations and Antimicrobial Activity of Metal Complexes of 2-(2-Furanylmethylaminocarbonyl)benzoic Acid

2011 ◽  
Vol 8 (1) ◽  
pp. 443-448 ◽  
Author(s):  
R. H. Patel ◽  
B. L. Hiran
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Transition Metal ◽  
Benzoic Acid ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Moments ◽  
Thermal Studies ◽  
Spectral Studies

The ligand, 2-(2-furanylmethylaminocarbonyl)benzoic acid (FMBA) and it’s transition metal complexes have been synthesized and characterized by elemental analysis, spectral studies, magnetic moments and thermal studies. The antifungal activity of all the samples was monitored against common fungi.

scholarly journals Synthesis, Characterization and Biological Activity of Transition Metal Complexes of [1-(2-bromo, 5-methoxy benzylidene) hydrazine] Ligand

2020 ◽  
Vol 10 (2) ◽  
pp. 2056-2062
Keyword(s):  
Antimicrobial Activity ◽  
Biological Activity ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Antimalarial Activity ◽  
Spectroscopic Methods ◽  
The Novel

A series of metal complexes was synthesized from the novel Schiff base [1-(2-bromo-5-methoxybenzylidene)-hydrazine] ligand. The ligand and metal complexes were well characterized by spectroscopic methods. The ligand was found to be monodentate. Stoichiometry of the ligand to metal ions was confirmed to be 4:1. Furthermore, the synthesized metal complexes were screened for antimicrobial, antitubercular, and antimalarial activities, which revealed that Cu (II) and Zn (II) showed excellent antimicrobial activity, Ni (II) was active against M. Tuberculosis, and Cd (II) showed excellent antimalarial activity.

scholarly journals SYNTHESIS, CHARACTERIZATION, IN VITRO ANTIMICROBIAL, ANTHELMINTIC AND DOCKING STUDIES OF NEW 2-[(E)-{[4-(1H-1,2,4-TRIAZOL-1 YLMETHYL)PHENYL]IMINO} METHYL]PHENOL, AND THEIR COMPLEXES WITH 3D METAL IONS

2016 ◽  
Vol 8 (9) ◽  
pp. 134
Author(s):  
Jithendra Kumara K.s. ◽  
Krishnamurthy G. ◽  
Sunil Kumar N.
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Research Work ◽  
Anthelmintic Activity ◽  
Triazole Ring ◽  
Diffusion Method

<p><strong>Objective: </strong>The main objectives of this research work is the synthesis and characterization of biologically potential triazole ring containing the Schiff base legend and their transition metal complexes, followed by screenings of their antimicrobial and anthelmintic activity the results of antimicrobial activity were compared with docking scores.</p><p><strong>Methods: </strong>The<strong> </strong>coordination complexes of Co(II), Cu(II), Fe(III) and Zn(II) with Schiff base derived ligand 4-(1<em>H</em>-1,2,4-triazol-1-ylmethyl) aniline and substituted aldehydes have been synthesized. The complexes are characterized by elemental analysis, conductivity measurements, electronic, IR, and <sup>1</sup>H NMR spectral data. The synthesized compounds were also screened <em>In vitro</em> antimicrobial activity was carried out according to diffusion method by using agar and potato dextrose agar at 100, 500 and 700 mg/ml concentrations in DMF.<strong> </strong>HEX 8.0<strong> </strong>programmers were used to perform the docking experiments on <em>nucleotide </em>of <em>S. typhi </em><em>at</em> as ligand [PDB: 3B6O].</p><p><strong>Results: </strong>Schiff base ligand and their transition metal complexes were studied for antimicrobial activity as well as docking. The results of both studies concluded that 4a, 4c and 4d compounds are more active in minimum inhibition concentration (30μg/ml) against <em>Staphylococcus aureus</em> (<em>S. aureus), Salmonella typhi (S. typlei)</em> bacteria and <em>Penicillium chrysogenum</em> (<em>P. Crysogenum) </em>fungi. The compounds showed highest docking score (-257.47,-275.61 and-280.17 respectively) with the secondary structure of the alpha-amylase with a nucleotide from <em>s. typhi</em> in the solid model. In the study of anthelmintic activity among these three compounds, 4d compound exhibits more activity compared with the standard.</p><strong>Conclusion: </strong>The compounds 4a, 4c and 4d were found to be more promising pharmacological activity this observation may promote a further development of this triazole group of compounds which may lead to better pharmacological profile than standard drugs. <p> </p>

Sign in / Sign up

Export Citation Format

Share Document