scholarly journals Risk Factors for Primary Clostridium difficile Infection; Results From the Observational Study of Risk Factors for Clostridium difficile Infection in Hospitalized Patients With Infective Diarrhea (ORCHID)

2020 ◽  
Vol 8 ◽  
Author(s):  
Kerrie Davies ◽  
Jody Lawrence ◽  
Claire Berry ◽  
Georgina Davis ◽  
Holly Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Observational Study ◽  
Clostridium Difficile Infection ◽  
Hospitalized Patients

scholarly journals Risk factors and outcomes of Clostridium difficile infection in hospitalized patients

2019 ◽  
Vol 42 (2) ◽  
pp. 99-106 ◽  
Author(s):  
Hao-Yuan Lee ◽  
Hsuan-Ling Hsiao ◽  
Chin-Yuan Chia ◽  
Chun-Wen Cheng ◽  
Tzu-Cheng Tsai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Hospitalized Patients

scholarly journals Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia

2016 ◽  
Vol 73 (1) ◽  
pp. 45-53 ◽  
Author(s):  
James D. Chalmers ◽  
Ahsan R. Akram ◽  
Aran Singanayagam ◽  
Mark H. Wilcox ◽  
Adam T. Hill
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Community Acquired Pneumonia ◽  
Hospitalized Patients

scholarly journals Clinical characterization and risk factors of Clostridium difficile infection in elderly patients in a Chinese hospital

2015 ◽  
Vol 9 (04) ◽  
pp. 381-387 ◽  
Author(s):  
Zhang Lihua ◽  
Dong Danfeng ◽  
Jiang Cen ◽  
Wang Xuefeng ◽  
Peng Yibing
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Elderly Patients ◽  
Clinical Features ◽  
Clostridium Difficile Infection ◽  
Gastrointestinal Disease ◽  
Statistical Tests ◽  
The Elderly ◽  
Hospitalized Patients ◽  
Elderly Hospitalized Patients

Introduction: Clostridium difficile is a common cause of nosocomial diarrhea, especially in elderly patients. This study aimed to analyze the clinical features and assess the risk factors associated with Clostridium difficile infection (CDI) in elderly hospitalized patients. Methodology: A retrospective case-control study was conducted among elderly hospitalized patients (> 60 years of age) in a Chinese tertiary hospital between 2010 and 2013. Fifty-two CDI patients and 150 randomly selected non-CDI patients were included in the study. Clinical features of CDI and non-CDI patients were compared by appropriate statistical tests. Logistic regression analyses were performed on a series of factors to determine the risk factors for CDI among the elderly hospitalized patients. Results: The elderly CDI patients showed higher leukocyte counts, lower serum albumin levels, longer duration of hospital stay, and higher mortality compared to the non-CDI patients. The proportion of patients admitted to the intensive care unit or exposed to gastric acid suppressants was also significantly different (p < 0.05) between the two groups. Multivariate analysis indicated that serum creatinine (OR 1.004; 95% CI 1.001–1.008), surgical intervention (OR 6.132; 95% CI 2.594–14.493), the number of comorbidities (OR 2.573; 95% CI 1.353–4.892), gastrointestinal disease (OR 4.670; 95% CI 2.002–10.895), and antibiotic use (OR 6.718; 95% CI 2.846–15.859) were independently associated with CDI. Conclusions: This study revealed several risk factors for CDI among elderly hospitalized patients. These findings will increase the knowledge concerning this disease and provide information regarding the control and prevention of CDI in the elderly.

Risk factors associated with Clostridium difficile infection severity in hospitalized patients

2014 ◽  
Vol 42 (6) ◽  
pp. 689-690 ◽  
Author(s):  
Mamoon A. Aldeyab ◽  
Susan Cliffe ◽  
Michael Scott ◽  
Peter Flanagan ◽  
Mary Kearney ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Hospitalized Patients ◽  
Factors Associated

scholarly journals Toxic megacolon complicating a Clostridium difficile infection in a pregnant woman

2010 ◽  
Vol 59 (1) ◽  
pp. 124-126 ◽  
Author(s):  
Alberto Candiotto ◽  
Irene Pascoli ◽  
Alessandra Gritti ◽  
Enrico Busato ◽  
Giuseppe Dal Pozzo
Keyword(s):  
Risk Factors ◽  
Pregnant Woman ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Toxic Megacolon ◽  
Antibiotic Use ◽  
Hospitalized Patients ◽  
Second Trimester ◽  
Traditional Risk Factors

Clostridium difficile infection (CDI) in non-hospitalized patients has been reported with increased frequency, whereas an association between CDI and pregnancy has not been highlighted. We report a case of toxic megacolon complicating a severe CDI during the second trimester of pregnancy in a patient without traditional risk factors, such as antibiotic use, immunodeficiency, and prolonged and recent hospitalization.

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