scholarly journals Lifetime and Momentary Psychotic Experiences in Adult Males and Females With an Autism Spectrum Disorder

2020 ◽  
Vol 11 ◽  
Author(s):  
Kim van der Linden ◽  
Claudia Simons ◽  
Thérèse van Amelsvoort ◽  
Machteld Marcelis
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Adult Males ◽  
Psychotic Experiences ◽  
Males And Females

scholarly journals A Genetic Multimutation Model of Autism Spectrum Disorder Fits Disparate Twin Concordance Data from the USA and Canada

2015 ◽  
Vol 2015 ◽  
pp. 1-10
Author(s):  
Ivan Kramer ◽  
Paul H. Lipkin ◽  
Alison R. Marvin ◽  
Paul A. Law
Keyword(s):  
Autism Spectrum Disorder ◽  
Age Of Onset ◽  
Autism Spectrum ◽  
Concordance Rate ◽  
Spectrum Disorder ◽  
Critical Test ◽  
The Usa ◽  
Males And Females ◽  
Kennedy Krieger Institute ◽  
Genetic Hypothesis

Whether autism spectrum disorder (ASD) is caused by genetics, environmental factors, or a combination of both is still being debated today. To help resolve this issue, a genetic multimutation model of ASD development was applied to a wide variety of age-of-onset data from the USA and Canada, and the model is shown to fit all the data. Included in this analysis is new, updated data from the Interactive Autism Network (IAN) of the Kennedy Krieger Institute in Baltimore, Maryland. We find that the age-of-onset distribution for males and females is identical, suggesting that ASD may be an autosomal disorder. The ASD monozygote concordance rate in twin data predicted by the genetic multimutation model is shown to be compatible with the observed rates. If ASD is caused entirely by genetics, then the ASD concordance rate of a cohort of monozygote twins should approach 100% as the youngest pair of twins in the cohort passes 10 years of age, a prediction that constitutes a critical test of the genetic hypothesis. Thus, by measuring the ASD concordance rate as a cohort of monozygote twins age, the hypothesis that this disorder is caused entirely by genetic mutations can be tested.

scholarly journals Sex differences in employment and supports for adults with autism spectrum disorder

Autism ◽  
2019 ◽  
Vol 23 (7) ◽  
pp. 1711-1719 ◽  
Author(s):  
Julie Lounds Taylor ◽  
Leann Smith DaWalt ◽  
Alison R Marvin ◽  
J Kiely Law ◽  
Paul Lipkin
Keyword(s):  
Autism Spectrum Disorder ◽  
Sex Differences ◽  
Family Support ◽  
The United States ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Internet Survey ◽  
Adults With Autism ◽  
Males And Females ◽  
Course Outcomes

This study explored sex differences in employment, reasons for unemployment, benefits, and supports among a large, international sample of adults with autism spectrum disorder. The sample included 443 adults with autism spectrum disorder (60% female; 74% residing in the United States) who consented to be part of an autism research registry and completed an Internet survey. Outcome variables included current employment status, number of hours working, number of jobs in the past 5 years, reasons for unemployment, as well as the number of benefits received and the amount of financial support currently being received from families of origin. Using multiple regression models, we found that males and females were working at similar rates. Females were more likely than males to say that their unemployment was a result of choosing to withdraw from the labor market. Similar percentages of males and females reported receiving some form of benefits or family support, but of those receiving benefits/family support, males received more than females. These results are consistent with other studies finding subtle, but potentially important sex differences in life-course outcomes of individuals with autism spectrum disorder.

scholarly journals Cortisol profiles differentiated in adolescents and young adult males with fragile X syndrome versus autism spectrum disorder

2017 ◽  
Vol 60 (1) ◽  
pp. 78-89 ◽  
Author(s):  
Sara M. Matherly ◽  
Jessica Klusek ◽  
Angela J. Thurman ◽  
Andrea McDuffie ◽  
Leonard Abbeduto ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Young Adult ◽  
Fragile X Syndrome ◽  
Fragile X ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Adult Males ◽  
Young Adult Males
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