scholarly journals A Pilot Randomized Control Trial With the Probiotic Strain Lactobacillus rhamnosus GG (LGG) in ADHD: Children and Adolescents Report Better Health-Related Quality of Life

2020 ◽  
Vol 11 ◽  
Author(s):  
Hojka Gregoric Kumperscak ◽  
Alja Gricar ◽  
Ina Ülen ◽  
Dusanka Micetic-Turk
Keyword(s):  
Lactobacillus Rhamnosus ◽  
Probiotic Strain ◽  
Health Related Quality ◽  
Lactobacillus Rhamnosus Gg ◽  
Adhd Children ◽  
Related Quality ◽  
Health Related ◽  
Randomized Control ◽  
Pilot Randomized Control Trial

The Effect of Physical Training in Children With Asthma on Pulmonary Function, Aerobic Capacity and Health-Related Quality of Life: A Systematic Review of Randomized Control Trials

2012 ◽  
Vol 24 (3) ◽  
pp. 472-489 ◽  
Author(s):  
Alison Crosbie
Keyword(s):  
Quality Of Life ◽  
Pulmonary Function ◽  
Aerobic Capacity ◽  
Physical Training ◽  
Health Related Quality ◽  
Children With Asthma ◽  
Related Quality ◽  
Health Related ◽  
Randomized Control

ObjectiveAsthma is a leading cause of chronic illness in children, impacting heavily on their daily life and participation in physical activity. The purpose of this systematic review was to investigate the evidence for the use of physical therapy to improve pulmonary function and aerobic capacity in children with asthma. Furthermore, the review aims to update previous literature on the effect of exercise on health related quality of life.MethodsA search was conducted for randomized control trials (RCTs) using the electronic databases Medline, Embase, SPORTDiscus, AMED, CINAHL, and The Cochrane Central Register of Controlled Trials. Studies were included if the participants were asthmatic children aged 6–18 years participating in any mode of physical exercise. Studies were reviewed for study quality, participant details, exercise intervention details, and intervention outcomes.ResultsA total of 16 studies and 516 subjects met inclusion criteria for review. Severity of asthma ranged from mild to severe. No improvement in pulmonary function was observed. Physical training led to an increase in aerobic capacity as measured by VO2max (mL/kg/min).ConclusionsFindings suggest that physical training does not improve pulmonary function in children with asthma, but does increase aerobic capacity. The small number of studies investigating quality of life suggests that physical training does improve health related quality of life; however further well designed randomized control trials are needed to verify these findings.

Results on health-related quality of life and functionality of a patient-centered self-management program in hospitalized COPD: a randomized control trial

2019 ◽  
Vol 42 (25) ◽  
pp. 3687-3695 ◽  
Author(s):  
Laura Lopez-Lopez ◽  
Marie Carmen Valenza ◽  
Janet Rodriguez-Torres ◽  
Irene Torres-Sanchez ◽  
Maria Granados-Santiago ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomized Control Trial ◽  
Management Program ◽  
Self Management ◽  
Health Related Quality ◽  
Patient Centered ◽  
Related Quality ◽  
Health Related ◽  
Randomized Control

scholarly journals Effect of Lactobacillus rhamnosus LGG® and Bifidobacterium animalis ssp. lactis BB-12® on health-related quality of life in college students affected by upper respiratory infections

2012 ◽  
Vol 109 (11) ◽  
pp. 1999-2007 ◽  
Author(s):  
Tracey J. Smith ◽  
Diane Rigassio-Radler ◽  
Robert Denmark ◽  
Timothy Haley ◽  
Riva Touger-Decker
Keyword(s):  
College Students ◽  
Respiratory Infections ◽  
Lactobacillus Rhamnosus ◽  
Health Related Quality ◽  
Bifidobacterium Animalis ◽  
Related Quality ◽  
Health Related ◽  
Upper Respiratory ◽  
Apparently Healthy

College students are susceptible to upper respiratory infections (URI) due to inadequate sleep, stress and close living quarters. Certain probiotic strains modulate immune function and may improve health-related quality of life (HRQL) during URI. The present study recruited apparently healthy college students and assessed the effect of probiotics on HRQL outcomes (i.e. self-reported duration, symptom severity and functional impairment of URI) in those who developed URI. Missed school and work days due to URI were also considered. Subjects (n 231) were apparently healthy college students living on campus in residence halls at the Framingham State University (Framingham, MA, USA), and were randomised to receive placebo (n 117) or probiotic-containing powder (daily dose of minimum 1 billion colony-forming units of each Lactobacillus rhamnosus LGG® (LGG®) and Bifidobacterium animalis ssp. lactis BB-12® (BB-12®); n 114) for 12 weeks. Subjects completed The Wisconsin Upper Respiratory Symptom Survey-21 to assess HRQL during URI. The final analyses included 198 subjects (placebo, n 97 and probiotics, n 101). The median duration of URI was significantly shorter by 2 d and median severity score was significantly lower by 34 % with probiotics v. placebo (P< 0·001), indicating a higher HRQL during URI. Number of missed work days was not different between groups (P= 0·429); however, the probiotics group missed significantly fewer school days (mean difference = 0·2 d) compared to the placebo group (P= 0·002). LGG® and BB-12® may be beneficial among college students with URI for mitigating decrements in HRQL. More research is warranted regarding mechanisms of action associated with these findings and the cost–benefit of prophylactic supplementation.

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