scholarly journals Vitamin D Deficiency During Pregnancy and Autism Spectrum Disorders Development

2020 ◽  
Vol 10 ◽  
Author(s):  
Nicola Principi ◽  
Susanna Esposito
Keyword(s):  
Vitamin D ◽  
Autism Spectrum Disorders ◽  
Vitamin D Deficiency ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals Calcium and Vitamin D Supplement Prescribing Practices among Providers Caring for Children with Autism Spectrum Disorders: Are We Addressing Bone Health?

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Shylaja Srinivasan ◽  
Julia O’Rourke ◽  
Sara Bersche Golas ◽  
Ann Neumeyer ◽  
Madhusmita Misra
Keyword(s):  
Vitamin D ◽  
Autism Spectrum Disorders ◽  
Children With Autism ◽  
Complementary Therapy ◽  
Autism Spectrum ◽  
Prescribing Practices ◽  
Mineral Density ◽  
Children With Asd ◽  
Spectrum Disorders ◽  
Vitamin D Supplement

Children with autism spectrum disorders (ASD) have several risk factors for low bone mineral density. The gluten-free, casein-free (GFCF) diet is a complementary therapy sometimes used in ASD that raises concerns for the adequacy of calcium and vitamin D intake. This study evaluated the prescribing practices of calcium and vitamin D supplements and the practice of checking 25-hydroxy vitamin D (25(OH)D) levels by providers in 100 children with ASD, 50 of whom were on the GFCF diet. Fifty-two percent and 46% of children on the GFCF diet were on some form of vitamin D and calcium supplements, respectively, compared to 18% and 14% of those not on this diet. Twenty-four percent of children in the GFCF group had a documented 25(OH)D level compared to none in the non-GFCF group. The data highlight a gap in calcium and vitamin D supplement prescribing practices among providers caring for children with ASD as well as a gap in the practice of checking 25(OH)D levels.

Pregnancy and Cord Vitamin D Status and Symptoms of Autism Spectrum Disorders in Toddlers: An Odense Child Cohort Study

2017 ◽  
Vol 41 (S1) ◽  
pp. S127-S127
Author(s):  
S.S.B. Clausen ◽  
H.T. Christesen ◽  
C. Dalgård ◽  
S. Lykkedegn ◽  
P. Munk-Jørgensen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Autism Spectrum Disorders ◽  
Early Pregnancy ◽  
Child Behavior Checklist ◽  
A Priori ◽  
Late Pregnancy ◽  
Autism Spectrum ◽  
Vitamin D Supplementation ◽  
Child Gender ◽  
Spectrum Disorders

IntroductionVitamin D deficiency is widespread globally in pregnant women and is suggested to contribute to offspring risk of symptoms of autism spectrum disorders (ASD), but findings are inconsistent.ObjectivesTo investigate whether low prenatal 25OHD exposure and 25OHD status in early life increase risk of early symptoms of ASD.AimsTo investigate early signs of ASD.MethodsFrom the prospective birth cohort, Odense child cohort (n = 2.549), Denmark, we included singletons with their mothers with available serum concentrations of 25OHD at early pregnancy (n = 1.231), late pregnancy (n = 1.361), and birth (n = 2.082). ASD symptoms were rated by parents on the pervasive developmental problem (PDP) scale of the Child behavior checklist for ages 1½-5 (CBCL 1½-5). Associations between 25OHD and PDP score were analyzed by multiple linear and logistic regression models. A priori included covariates were gestational age, child gender, birth weight, season of birth, parity, parental psychiatric diagnoses, maternal age, smoking habits, alcohol consumption, education level, vitamin D supplementation, and pre-gestational BMI.ResultsMeans (SD) of 25OHD for early pregnancy, late pregnancy, and cord were 65.5 (21.5), 78.7 (27.0), and 47.0 (21.7) nmol/L, respectively. PDP data were obtained at a mean (SD) of 2.7 (0.6) years of age. Data from the regression analyses are pending.ConclusionsIn this well-off cohort with relatively high levels of cord 25OHD, power calculations allows us to detect a true change of 0.02 PDP scores per 10 nmol/L change in 25OHD. Further studies will clarify whether early PDP scores track later ASD diagnosis.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Vitamin d status in TUNISIAN children with autism spectrum disorders

2019 ◽  
Vol 493 ◽  
pp. S619-S620
Author(s):  
M. Chtourou ◽  
M. Naifar ◽  
S. Grayaa ◽  
I. Hajkacem ◽  
D. Ben Touhemi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Autism Spectrum Disorders ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Vitamin D Status ◽  
Spectrum Disorders

scholarly journals Maternal vitamin D deficiency and the risk of autism spectrum disorders: population-based study

BJPsych Open ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 170-172 ◽  
Author(s):  
Cecilia Magnusson ◽  
Kyriaki Kosidou ◽  
Christina Dalman ◽  
Michael Lundberg ◽  
Brian K. Lee ◽  
...  
Keyword(s):  
Vitamin D ◽  
Intellectual Disability ◽  
Vitamin D Deficiency ◽  
Population Based ◽  
Autism Spectrum ◽  
Population Based Study ◽  
Maternal Vitamin ◽  
Increase Risk ◽  
Spectrum Disorders ◽  
The Relationship

BackgroundMaternal vitamin D deficiency may increase risk of autism spectrum disorder (ASD), but direct evidence is lacking.AimsTo clarify the relationship between maternal vitamin D deficiency and offspring risk of ASD with and without intellectual disability.MethodUsing a register-based total population study (N=509 639), we calculated adjusted odds ratios (aORs) and 95% confidence intervals (CIS) of ASD with and without intellectual disability in relation to lifetime diagnoses of maternal vitamin D deficiency. Although rare, such deficiency was associated with offspring risk of ASD with, but not without, intellectual disability (aORs 2.51, 95% CI 1.22–5.16 and 1.28, 0.68–2.42). Relationships were stronger in non-immigrant children.ConclusionsIf reflecting associations for prenatal hypovitaminosis, these findings imply gestational vitamin D substitution as a means of ASD prevention.

Vitamin D Levels during Pregnancy in Relation to Autism Spectrum Disorders (ASD) in Offspring; the Early Markers for Autism (EMA) Study in California

2018 ◽  
Vol 2017 (1) ◽  
pp. 376
Author(s):  
Gayle C. Windham ◽  
Meredith C. Anderson ◽  
Darryl Eyles ◽  
Kristen Lyall ◽  
Karen L. Jones ◽  
...  
Keyword(s):  
Vitamin D ◽  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Vitamin D Levels ◽  
Early Markers ◽  
Spectrum Disorders
Sign in / Sign up

Export Citation Format

Share Document