scholarly journals Support Vector Machine Analysis of Functional Magnetic Resonance Imaging of Interoception Does Not Reliably Predict Individual Outcomes of Cognitive Behavioral Therapy in Panic Disorder with Agoraphobia

2017 ◽  
Vol 8 ◽  
Author(s):  
Benedikt Sundermann ◽  
Jens Bode ◽  
Ulrike Lueken ◽  
Dorte Westphal ◽  
Alexander L. Gerlach ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Support Vector Machine ◽  
Magnetic Resonance ◽  
Panic Disorder ◽  
Behavioral Therapy ◽  
Support Vector ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Individual Outcomes ◽  
Machine Analysis

scholarly journals Multilevel Clustering-Evolutionary Random Support Vector Machine Cluster Algorithm-Based Blood Oxygenation Level-Dependent Functional Magnetic Resonance Imaging Images in Analysis of Therapeutic Effects on Cerebral Ischemic Stroke

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zhili Zhang ◽  
Guo Cheng ◽  
Guifang Liu ◽  
Gaixia Li
Keyword(s):  
Magnetic Resonance Imaging ◽  
Support Vector Machine ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Motor Area ◽  
Support Vector ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Activation Rate ◽  
Sensory Motor

The study aimed to explore the relationship between cerebral ischemic stroke (CIS) and the patient’s limb movement through the blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI) based on multilevel clustering-evolutionary random support vector machine cluster (MCRSVMC). Specifically, 20 CIS patients were defined as the experimental group; another 20 healthy volunteers were defined as the control group. All subjects performed finger movement and verb association task. The performance of support vector machine (SVM) and MCRSVMC algorithm was compared and applied to functional magnetic resonance imaging (fMRI) of blood oxygen level in all subjects. The results showed that the average accuracy of MCRSVMC algorithm was significantly higher than that of support vector machine (86.75%, 65.84%; P < 0.05 ). The sensitivity of MCRSVMC algorithm was significantly higher than that of support vector machine (92.52%, 75.41%; P < 0.05 ). In addition, the specificity of MCRSVMC algorithm was significantly higher than that of support vector machine (86.39%, 68.24%; P < 0.05 ). When CIS patients performed finger exercise, the sensory motor areas on both sides were significantly activated, and the activated sensory motor areas on both sides were significantly bigger than the ipsilateral area. The activation rate of the left-sensory motor area (L-SM1) was 87.5%, the activation rate of the right-sensory motor area (R-SM1) was 25%, the activation rate of the left-side auxiliary motor area (L-SMA) was 62.5%, and the activation rate of the right-side auxiliary motor area (R-SMA) was 37.5%. In conclusion, the MCRSVMC algorithm proposed in this study is highly efficient and stable. BOLD-fMRI diagnosis of motor function in CIS patients is mainly related to compensation around the lesion, which occurs on the healthy side after recovery.

scholarly journals Applying 3DPCANet and Functional Magnetic Resonance Imaging to Aided Diagnosis of Alzheimer’s Disease

2021 ◽  
Author(s):  
Yu Wang ◽  
Hongfei Jia ◽  
Yifan Duan ◽  
Hongbing Xiao
Keyword(s):  
Magnetic Resonance Imaging ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Brain Regions ◽  
Support Vector ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Public Data

Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease, which changes the structure of brain regions by some hidden causes. In this paper for assisting doctors to make correct judgments, an improved 3DPCANet method is proposed to classify AD by combining the mean (mALFF) of the whole brain. The main idea includes that firstly, the functional magnetic resonance imaging (fMRI) data is pre-processed, and mALFF is calculated to get the corresponding matrix. Then the features of mALFF images are extracted via the improved 3DPCANet network. Finally, AD patients with different stages are classified using support vector machine (SVM). Experiments results based on public data from the Alzheimer’s disease neuroimaging initiative (ADNI) show that the proposed approach has better performance compared with state-of-the-art methods. The accuracies of AD vs. significant memory concern (SMC), SMC vs. late mild cognitive impairment (LMCI), and normal control (NC) vs. SMC reach respectively 92.42%, 91.80%, and 89.50%, which testifies the feasibility and effectiveness of the proposed method.

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