scholarly journals Both High Cognitive Load and Transcranial Direct Current Stimulation Over the Right Inferior Frontal Cortex Make Truth and Lie Responses More Similar

2020 ◽  
Vol 11 ◽  
Author(s):  
Nuria Sánchez ◽  
Jaume Masip ◽  
Carlos J. Gómez-Ariza
Keyword(s):  
Cognitive Load ◽  
Frontal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation ◽  
Inferior Frontal Cortex ◽  
The Right

Modulation of sustained fear by transcranial direct current stimulation (tDCS) of the right inferior frontal cortex (rIFC)

2018 ◽  
Vol 139 ◽  
pp. 173-177 ◽  
Author(s):  
Martin J. Herrmann ◽  
Bibiane S.E. Simons ◽  
Anna K. Horst ◽  
Stephanie Boehme ◽  
Thomas Straube ◽  
...  
Keyword(s):  
Frontal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation ◽  
Inferior Frontal Cortex ◽  
The Right

scholarly journals Neural changes after training with transcranial direct current stimulation to increase speech fluency in adults who stutter

2021 ◽  
Author(s):  
Jennifer Chesters ◽  
Riikka Möttönen ◽  
Kate E Watkins
Keyword(s):  
Frontal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Inter Quartile Range ◽  
Sham Stimulation ◽  
Direct Current Stimulation ◽  
Speech Fluency ◽  
Adult Men ◽  
Sentence Reading ◽  
Inferior Frontal Cortex

In a randomised controlled trial, we showed that a five-day intervention combining anodal transcranial direct current stimulation over the left inferior frontal cortex with temporary speech fluency enhancing techniques reduces stuttering. Speech fluency was unchanged by the fluency training alone, as predicted. Here, we report the neural changes associated with the intervention, measured using functional MRI during sentence reading before the training and one-week later. We obtained imaging data in 25 adult men who stutter (median age = 32 y, inter-quartile range = 11) at the pre-intervention baseline and again one-week post-intervention. A control group of 15 adult men who do not stutter (median age = 30 y, inter-quartile range = 10) and did not complete the intervention were scanned on one occasion. In a whole-brain analysis of perceptibly fluent sentence reading, we compared the change in task-evoked neural activity in the sub-group of men who stutter who had received active stimulation during the intervention (N=13) with those who had sham stimulation (N=12). We hypothesised that the combination of anodal stimulation over the left inferior frontal cortex and fluency-enhancing training would result in lasting change to the brain networks supporting fluent speech production. An additional region-of-interest analysis explored effects on basal ganglia nuclei, which are thought to have a key role in the casual mechanism of stuttering, and which we hypothesised would be engaged by the behavioural approach used during training (choral and metronome-timed speaking). One week after the intervention, the group who had received active transcranial stimulation showed increased activity in speech-related brain regions, relative to the group who had received sham stimulation. Cortically, these changes were evident in left inferior frontal cortex (pars opercularis and orbitalis), anterior insula, anterior superior temporal gyrus, anterior cingulate cortex, and supplementary motor area. Subcortically, activation increased in the caudate nuclei and putamen bilaterally, and in right globus pallidus and thalamus. Together these regions form cortico-striatal-thalamo-cortical loops involved in the planning and initiation and control of speech movements.Our findings reveal that the mechanism of action of the tDCS intervention involved increasing activity across the network involved in the production of fluent speech, indicating that tDCS can be used to promote neural plasticity to strengthen networks supporting natural fluency. This study advances the potential of using non-invasive brain stimulation to improve therapy efficacy for those people who stutter who choose to work on increasing fluency.

Interference effects of transcranial direct current stimulation over the right frontal cortex and adrenergic system on conditioned fear

2017 ◽  
Vol 234 (22) ◽  
pp. 3407-3416 ◽  
Author(s):  
Mohammad Nasehi ◽  
Reyhaneh Soltanpour ◽  
Mohaddeseh Ebrahimi-Ghiri ◽  
Shahram Zarrabian ◽  
Mohammad-Reza Zarrindast
Keyword(s):  
Frontal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Conditioned Fear ◽  
Adrenergic System ◽  
Interference Effects ◽  
Direct Current Stimulation ◽  
The Right

scholarly journals Transcranial direct current stimulation over left inferior frontal cortex improves speech fluency in adults who stutter

2018 ◽  
Author(s):  
Jennifer Chesters ◽  
Riikka Möttönen ◽  
Kate E. Watkins
Keyword(s):  
Frontal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Neurodevelopmental Disorder ◽  
Anodal Tdcs ◽  
Direct Current Stimulation ◽  
Speech Fluency ◽  
Fluency Intervention ◽  
Inferior Frontal Cortex ◽  
Adults Who Stutter

Stuttering is a neurodevelopmental disorder affecting 5% of children, and persisting in 1% of adults. Promoting lasting fluency improvement in adults who stutter is a particular challenge. Novel interventions to improve outcomes are required, therefore. Previous work in patients with acquired motor and language disorders reported enhanced benefits of behavioural therapies when paired with transcranial direct current stimulation (tDCS). Here, we report the results of the first trial investigating whether tDCS can improve speech fluency in adults who stutter. Thirty adult men who stutter completed a randomized, double-blind, controlled trial of anodal tDCS over left inferior frontal cortex. Fifteen men received 20 minutes of 1-mA tDCS on five consecutive days while speech fluency was temporarily induced using choral and metronome-timed speech. The other 15 men received the same speech fluency intervention with sham stimulation. We predicted that applying anodal tDCS to the left inferior frontal cortex during speech production with temporary fluency inducers would result in longer-lasting fluency improvements. Speech fluency during reading and conversation was assessed at baseline, before and after the stimulation on each day of the five-day intervention, and at 1 and 6 weeks after the end of the intervention. TDCS combined with speech fluency training significantly reduced the percentage of disfluent speech measured 1 week after the intervention compared with fluency intervention alone. At 6 weeks after the intervention, this improvement was maintained during reading but not during conversation. Outcome scores at both post-intervention time points on a clinical assessment tool (the Stuttering Severity Instrument – version 4) also showed significant improvement in the group receiving tDCS compared with the sham group, in whom fluency was unchanged from baseline. We conclude that tDCS combined with behavioural fluency intervention has the capacity to improve fluency in adults who stutter. tDCS thereby offers a potentially useful adjunct to future speech therapy interventions for this population, for whom therapy outcomes are currently limited.

Sign in / Sign up

Export Citation Format

Share Document