scholarly journals Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 10 ◽  
Author(s):  
Qian-Wen Xie ◽  
Xiaolu Dai ◽  
Xinfeng Tang ◽  
Celia H. Y. Chan ◽  
Cecilia L. W. Chan
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Mental Disorders ◽  
Children And Adolescents ◽  
Meta Analysis

scholarly journals Are prenatal anxiety or depression symptoms associated with asthma or atopic diseases throughout the offspring’s childhood? An updated systematic review and meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shuguang Chen ◽  
Sheng Chen
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Mental Disorders ◽  
Childhood Asthma ◽  
Meta Analysis ◽  
Atopic Disease ◽  
Cochrane Library ◽  
Depression Symptoms ◽  
Atopic Diseases ◽  
Random Effects Models

Abstract Background Asthma is the most common respiratory disease among children, while atopic diseases such as atopic dermatitis affect about 20% of infants under 2 years of age. Studies suggested that these conditions might be related to prenatal depression or anxiety. This study aimed to explore the association between prenatal mental disorders and childhood asthma or atopic disease in a systematic review and meta-analysis. Methods PubMed, Embase, and the Cochrane Library were searched up to May 2020. The primary outcome was childhood asthma and childhood atopic dermatitis. Random-effects models were used because of high heterogeneity indicated by I2 > 50% and Q-test P < 0.10. Results A total of 598 studies were initially identified, but nine studies met the inclusion criteria. Prenatal mental disorder was associated with childhood asthma (n = 6 studies; ES = 1.146, 95%CI: 1.054–1.245, P = 0.001; I2 = 93.5%, Pheterogeneity < 0.001) whereas no significant association was found for childhood atopic dermatitis (n = 4 studies; ES = 1.211, 95%CI: 0.982–1.494, P = 0.073; I2 = 78.5%, Pheterogeneity < 0.001). Childhood asthma seems to be related more to depression (n = 1 study; ES = 1.170, 95%CI: 1.061–1.291, P = 0.002) and anxiety/depression (n = 4 studies; ES = 1.157, 95%CI: 1.050–1.275, P = 0.073; I2 = 95.3%, Pheterogeneity < 0.001). Conclusion This meta-analysis demonstrated that prenatal mental disorders increase the risk of childhood asthma. We limited the included samples to pregnant women to investigate the association between prenatal psychological factors and offspring’s physical health. Future studies should include large high-quality cohort studies to investigate the behavioral, environmental, and genetic causes for this association.

scholarly journals Does prenatal anxiety or depression symptoms are associated with asthma or atopic diseases throughout the offspring’s childhood? An updated systematic review and meta-analysis

2021 ◽  
Author(s):  
Shuguang Chen ◽  
Sheng Chen
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Mental Disorders ◽  
Childhood Asthma ◽  
Meta Analysis ◽  
Atopic Disease ◽  
Cochrane Library ◽  
Depression Symptoms ◽  
Atopic Diseases ◽  
Random Effects Models

Abstract BackgroundAsthma is the most common respiratory disease among children, while atopic diseases such as atopic dermatitis affect about 20% of infants under 2 years old. Recently, studies suggest that they may all be related to prenatal depression or anxiety, but further research and analysis are needed. This study aimed to explore the association between prenatal mental disorders and childhood asthma or atopic disease in a systematic review and meta-analysis of nine studies. MethodsPubMed, Embase, and Cochrane Library were searched up to May 2020. The primary outcome was childhood asthma and childhood atopic dermatitis. Random-effects models were used because of high heterogeneity indicated by I2 >50% and Q-test P<0.10. ResultsA total of 598 studies were initially identified, but nine studies met the inclusion criteria. Prenatal mental disorder was associated with childhood asthma (n=6 studies; ES=1.146, 95%CI: 1.054-1.245, P=0.001; I2=93.5%, Pheterogeneity<0.001) whereas no significant association was found for childhood atopic dermatitis (n=4 studies; ES=1.211, 95%CI: 0.982-1.494, P=0.073; I2=78.5%, Pheterogeneity<0.001). Childhood asthma seems to be related more to depression (n=1 study; ES=1.170, 95%CI: 1.061-1.291, P=0.002) and anxiety/depression (n=4 studies; ES=1.157, 95%CI: 1.050-1.275, P=0.073; I2=95.3%, Pheterogeneity<0.001). ConclusionThis meta-analysis demonstrated that prenatal mental disorders increase the risk of childhood asthma. We limited the included samples to pregnant women to investigate the association between prenatal psychological factors and offspring’s physical health. Future studies should include large high-quality cohort studies to investigate the behavioral, environmental, and genetic causes for this association.

scholarly journals The association of inadequate lip coverage and malocclusion with dental trauma in Brazilian children and adolescents – A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Walbert de Andrade Vieira ◽  
Vanessa Gallego Arias Pecorari ◽  
Paulo Henrique Gabriel ◽  
Júlio Vargas‐Neto ◽  
Eduardo César Almada Santos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Children And Adolescents ◽  
Meta Analysis ◽  
Dental Trauma ◽  
Brazilian Children
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