scholarly journals Adaptive Computerized Working Memory Training in Patients With Mild Cognitive Impairment. A Randomized Double-Blind Active Controlled Trial

2019 ◽  
Vol 10 ◽  
Author(s):  
Marianne M. Flak ◽  
Haakon R. Hol ◽  
Susanne S. Hernes ◽  
Linda Chang ◽  
Andreas Engvig ◽  
...  
Keyword(s):  
Working Memory ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Controlled Trial ◽  
Working Memory Training ◽  
Memory Training ◽  
Double Blind

scholarly journals Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training

2016 ◽  
Vol 28 (10) ◽  
pp. 1471-1483 ◽  
Author(s):  
Joni Holmes ◽  
Elizabeth M. Byrne ◽  
Susan E. Gathercole ◽  
Michael P. Ewbank
Keyword(s):  
Working Memory ◽  
Cognitive Abilities ◽  
Controlled Trial ◽  
Random Noise ◽  
Working Memory Training ◽  
Memory Training ◽  
Double Blind ◽  
Transcranial Random Noise Stimulation ◽  
Therapeutic Value ◽  
First Time

Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults completed 10 sessions of Cogmed Working Memory Training with either active tRNS or sham stimulation applied bilaterally to dorsolateral pFC. Training was associated with gains on both the training tasks and on untrained tests of working memory that shared overlapping processes with the training tasks, but not with improvements on working memory tasks with distinct processing demands or tests of other cognitive abilities (e.g., IQ, maths). There was no evidence that tRNS increased the magnitude or transfer of these gains. Thus, combining tRNS with Cogmed Working Memory Training provides no additional therapeutic value.

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