scholarly journals Just Swap Out of Negative Vibes? Rumination and Inhibition Deficits in Major Depressive Disorder: Data from Event-Related Potentials Studies

2016 ◽  
Vol 7 ◽  
Author(s):  
Aurore Monnart ◽  
Charles Kornreich ◽  
Paul Verbanck ◽  
Salvatore Campanella
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Event Related Potentials ◽  
Major Depressive ◽  
Related Potentials

The effect of erroneous responses on response monitoring in patients with major depressive disorder: A study with event-related potentials

2004 ◽  
Vol 41 (6) ◽  
pp. 833-840 ◽  
Author(s):  
Martin Ruchsow ◽  
Barbel Herrnberger ◽  
Christiane Wiesend ◽  
Georg Gron ◽  
Manfred Spitzer ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Event Related Potentials ◽  
Response Monitoring ◽  
Major Depressive ◽  
Related Potentials

Error processing in major depressive disorder: Evidence from event-related potentials

2006 ◽  
Vol 40 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Martin Ruchsow ◽  
Bärbel Herrnberger ◽  
Petra Beschoner ◽  
Georg Grön ◽  
Manfred Spitzer ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Event Related Potentials ◽  
Error Processing ◽  
Major Depressive ◽  
Related Potentials

scholarly journals Mismatch Negativity and Loudness Dependence of Auditory Evoked Potentials among Patients with Major Depressive Disorder, Bipolar II Disorder, and Bipolar I Disorder

2020 ◽  
Vol 10 (11) ◽  
pp. 789
Author(s):  
Yang Rae Kim ◽  
Young-Min Park
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Evoked Potentials ◽  
Mismatch Negativity ◽  
Auditory Evoked Potentials ◽  
Type I ◽  
Major Depressive ◽  
Serotonergic Activity ◽  
Related Potentials ◽  
Loudness Dependence

Mismatch negativity (MMN) and loudness dependence of auditory evoked potentials (LDAEP), which are event-related potentials, have been investigated as biomarkers. MMN indicates the pre-attentive function, while LDAEP may be an index of central serotonergic activity. This study aimed to test whether MMN and LDAEP are useful biological markers for distinguishing patients with bipolar disorder (BD) and major depressive disorder (MDD), as well as the relationship between MMN and LDAEP. Fifty-five patients with major depressive episodes, aged 20 to 65 years, who had MDD (n = 17), BD type II (BIID) (n = 27), and BD type I (BID) (n = 11), were included based on medical records. Patients with MDD had a higher MMN amplitude than those with BID. In addition, the MMN amplitude in F4 positively correlated with the Korean version of mood disorder questionnaire scores (r = 0.37, p = 0.014), while the MMN amplitude in F3 correlated negatively with LDAEP (r = −0.30, p = 0.024). The odds ratios for the BID group and some variables were compared with those for the MDD group using multinomial logistic regression analysis. As a result, a significant reduction of MMN amplitude was found under BID diagnosis compared to MDD diagnosis (p = 0.015). This study supported the hypothesis that MMN amplitude differed according to MDD, BIID, and BID, and there was a relationship between MMN amplitude and LDAEP. These findings also suggested that BID patients had a reduced automatic and pre-attentive processing associated with serotonergic activity or N-methyl-D-aspartate receptor.

MMN-Indexed Auditory Change Detection in Major Depressive Disorder

2020 ◽  
Vol 51 (6) ◽  
pp. 365-372 ◽  
Author(s):  
Jenna N. Bissonnette ◽  
Ashley M. Francis ◽  
Krista M. Hull ◽  
Jennifer Leckey ◽  
Laura Pimer ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Auditory Cortex ◽  
Change Detection ◽  
Community Dwelling ◽  
Major Depressive ◽  
Severity Scores ◽  
Wide Range ◽  
Related Potentials ◽  
Auditory Change Detection

In major depressive disorder (MDD), event-related potentials that are involved in auditory cortex function (i.e. N100 and P300) often have greater latencies and decreased amplitudes. The auditory mismatch negativity (MMN) is thought to be produced by generators in the auditory cortex, as well as the frontal lobes. Reports on differences in MMN in those with MDD have been varied. It was hypothesized that the wide range of results in the literature may be due to the use of different deviant types in eliciting the MMN. To attempt and explain these inconsistencies, the current study employed a multifeature MMN paradigm with 5 deviant tone types in community-dwelling participants with a diagnosis of MDD. We found those with MDD had higher MMN amplitudes following tones that deviated in intensity and location, but no difference in MMNs elicted by the other deivants (relative to unaffected controls). Location MMN deviants were negatively correlated with depression severity scores (i.e. larger MMN with greater severity). We also found longer MMN latencies following the pitch deviant. These results suggest the early auditory change detection process is altered in MDD, but only following certain types of auditory stimuli. Potential explanations for these findings, including high levels of anxiety and the influence of tryptophan are explored. Equally, the current report highlights the importance of using various deviant types when examining the MMN in clinical populations.

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