scholarly journals Providing Extrinsic Reward for Test Performance Undermines Long-Term Memory Acquisition

2016 ◽  
Vol 7 ◽  
Author(s):  
Christof Kuhbandner ◽  
Alp Aslan ◽  
Kathrin Emmerdinger ◽  
Kou Murayama
Keyword(s):  
Test Performance ◽  
Long Term Memory ◽  
Extrinsic Reward ◽  
Term Memory ◽  
Memory Acquisition

scholarly journals Neuronal reactivation during post-learning sleep consolidates long-term memory in Drosophila

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Ugur Dag ◽  
Zhengchang Lei ◽  
Jasmine Q Le ◽  
Allan Wong ◽  
Daniel Bushey ◽  
...  
Keyword(s):  
Memory Consolidation ◽  
Dopaminergic Neurons ◽  
Learning Experience ◽  
Long Term Memory ◽  
Term Memory ◽  
Long Term Storage ◽  
Memory Acquisition ◽  
Underlying Mechanisms ◽  
Term Storage

Animals consolidate some, but not all, learning experiences into long-term memory. Across the animal kingdom, sleep has been found to have a beneficial effect on the consolidation of recently formed memories into long-term storage. However, the underlying mechanisms of sleep dependent memory consolidation are poorly understood. Here, we show that consolidation of courtship long-term memory in Drosophila is mediated by reactivation during sleep of dopaminergic neurons that were earlier involved in memory acquisition. We identify specific fan-shaped body neurons that induce sleep after the learning experience and activate dopaminergic neurons for memory consolidation. Thus, we provide a direct link between sleep, neuronal reactivation of dopaminergic neurons, and memory consolidation.

scholarly journals Disconnection Syndrome and Verbal, Spatial and Tactile Amnesia following a Tumor of the Splenium of the Corpus Callosum

1990 ◽  
Vol 3 (2) ◽  
pp. 65-75
Author(s):  
Marina Scarpa ◽  
Paolo Sorgato
Keyword(s):  
Corpus Callosum ◽  
Test Performance ◽  
Short Term Memory ◽  
Long Term Memory ◽  
Term Memory ◽  
Disconnection Syndrome ◽  
Amnesic Syndrome ◽  
Topographical Disorientation ◽  
Tactile Memory

A patient with a severe amnesic syndrome following a glioma of the splenium of the corpus callosum is reported. The long-term memory deficit involved anterograde as well as retrograde events dating back to 40 years and causing topographical disorientation. Short-term memory test performance was in the normal range, with the exception of tactile memory which was severely impaired. The patient also showed disconnection symptoms, due to severing of occipito-parietal and parieto-temporal connections, while parieto-parietal connections were undamaged.

Long-Term Memory Performance in Adult ADHD

2016 ◽  
Vol 21 (4) ◽  
pp. 267-283 ◽  
Author(s):  
Timo Skodzik ◽  
Heinz Holling ◽  
Anya Pedersen
Keyword(s):  
Visual Memory ◽  
Adult Adhd ◽  
Memory Performance ◽  
Meta Analysis ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Tests ◽  
Memory Acquisition ◽  
Meta Analyses

Objective: Memory problems are a frequently reported symptom in adult ADHD, and it is well-documented that adults with ADHD perform poorly on long-term memory tests. However, the cause of this effect is still controversial. The present meta-analysis examined underlying mechanisms that may lead to long-term memory impairments in adult ADHD. Method: We performed separate meta-analyses of measures of memory acquisition and long-term memory using both verbal and visual memory tests. In addition, the influence of potential moderator variables was examined. Results: Adults with ADHD performed significantly worse than controls on verbal but not on visual long-term memory and memory acquisition subtests. The long-term memory deficit was strongly statistically related to the memory acquisition deficit. In contrast, no retrieval problems were observable. Conclusion: Our results suggest that memory deficits in adult ADHD reflect a learning deficit induced at the stage of encoding. Implications for clinical and research settings are presented.

5-HT4 receptor binding in hippocampus or prefrontal cortex is not associated with long-term memory test performance

NeuroImage ◽  
2010 ◽  
Vol 52 ◽  
pp. S59
Author(s):  
M.T. Haahr ◽  
K. Madsen ◽  
L. Marner ◽  
A. Gade ◽  
E.L. Mortensen ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Receptor Binding ◽  
Test Performance ◽  
Memory Test ◽  
Long Term Memory ◽  
Term Memory

scholarly journals Methamphetamine Inhibits Long-Term Memory Acquisition and Synaptic Plasticity by Evoking Endoplasmic Reticulum Stress

2021 ◽  
Vol 14 ◽  
Author(s):  
Guang Chen ◽  
Xiaoning Wei ◽  
Xiang Xu ◽  
Gang Yu ◽  
Zheng Yong ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Synaptic Plasticity ◽  
Er Stress ◽  
Memory Loss ◽  
Translation Initiation Factor ◽  
Long Term Memory ◽  
Term Memory ◽  
Expression Levels ◽  
Memory Acquisition

Methamphetamine (MA), an illicit drug abused worldwide, leads to cognitive impairment and memory loss. However, the detailed mechanisms of MA-induced neurologic impairment are still unclear. The present study aimed to investigate the mechanisms of MA-induced inhibition of memory acquisition from the perspective of endoplasmic reticulum (ER) stress. ER stress, caused by the accumulation of wrongly folded proteins in the ER, is important for new protein synthesis, which further influence the formation of long-term memory. A subacute MA poisoning model of mice was established and several behavioral experiments were performed, including elevated plus maze, Morris water maze, electro-stimulus Y-maze, and novel object recognition tasks. The present results suggested that 4 days exposure to MA induced significant memory loss. Whereas, this damage to memory formation could be protected when mice were pre-treated with ER stress inhibitor, tauroursodeoxycholic acid (TUDCA). The results of Western blotting showed that subacute exposure to MA increased the expression levels of ER stress marker proteins, such as binding immunoglobulin protein, phosphorylated eukaryotic translation initiation factor 2α, cyclic AMP-dependent transcription factor (ATF)-4, ATF-6, and CCAAT-enhancer binding protein homologous protein. Meanwhile, the enhanced expression levels of these proteins were reversed by TUDCA, indicating that MA administration induced memory loss by evoking ER stress in the hippocampus. We also found that MA inhibited the induction of long-term potentiation (LTP) in the hippocampus. Nevertheless, LTP could be induced when mice were pre-treated with TUDCA. In conclusion, MA inhibited long-term memory acquisition and synaptic plasticity via ER stress.

scholarly journals Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats

2019 ◽  
Vol 41 (1) ◽  
pp. 45014
Author(s):  
Luís Flávio Souza de Oliveira ◽  
Miriam Staudt ◽  
Michel Mansur Machado ◽  
Alexandre Meneghello Fuentefria
Keyword(s):  
Anabolic Androgenic Steroids ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Acquisition ◽  
Androgenic Steroids

scholarly journals The Influence of Poststudy Action Congruency on Memory Consolidation

2020 ◽  
Vol 67 (4) ◽  
pp. 211-223
Author(s):  
René Zeelenberg ◽  
Sebastiaan Remmers ◽  
Florence Blaauwgeers ◽  
Diane Pecher
Keyword(s):  
Memory Consolidation ◽  
Test Performance ◽  
Initial Study ◽  
Memory Test ◽  
Long Term Memory ◽  
Term Memory ◽  
Motor Actions ◽  
Better Than

Abstract. The actions associated with objects are thought to be automatically activated when processing object names. Recent studies, however, have failed to find evidence for a role of the motor system in long-term memory for objects. One exception is a study by van Dam et al. (2013) in which participants studied object names associated with pressing (e.g., doorbell) or twisting (e.g., jar), followed by pressing or twisting actions in a seemingly unrelated task. In the final memory test, performance for action congruent words was better than for action incongruent words. We aimed to generalize these findings. In Experiments 1 and 2, we found no effect of action congruency on repetition priming in lexical decision and man-made/natural decision. In Experiment 3, the action congruency manipulation was administered immediately after initial study or a day later, just prior to the recognition memory test. We found no effects of action congruency and timing of the action. Finally, Experiment 4 was a direct replication of Experiment 1 of van Dam et al. (2013) . Again, we failed to find an effect of poststudy action congruency. Thus, we obtained no evidence for the view that motor actions play a role in long-term memory for objects.

More than working memory rides on long-term memory

2003 ◽  
Vol 26 (6) ◽  
pp. 737-737 ◽  
Author(s):  
Joaquín M. Fuster
Keyword(s):  
Working Memory ◽  
Cognitive Functions ◽  
Single Unit ◽  
Neural Mechanism ◽  
Long Term Memory ◽  
Term Memory ◽  
Target Article ◽  
Memory Acquisition

Single-unit data from the cortex of monkeys performing working-memory tasks support the main point of the target article. Those data, however, also indicate that the activation of long-term memory is essential to the processing of all cognitive functions. The activation of cortical long-term memory networks is a key neural mechanism in attention (working memory is a form thereof), perception, memory acquisition and retrieval, intelligence, and language.

Sign in / Sign up

Export Citation Format

Share Document