scholarly journals OsDIRP1, a Putative RING E3 Ligase, Plays an Opposite Role in Drought and Cold Stress Responses as a Negative and Positive Factor, Respectively, in Rice (Oryza sativa L.)

2018 ◽  
Vol 9 ◽  
Author(s):  
Li Hua Cui ◽  
Hye Jo Min ◽  
Mi Young Byun ◽  
Hyeong Geun Oh ◽  
Woo Taek Kim
2012 ◽  
Vol 366 (1-2) ◽  
pp. 647-658 ◽  
Author(s):  
Yufeng Song ◽  
Jin Cui ◽  
Hongxiao Zhang ◽  
Guiping Wang ◽  
Fang-Jie Zhao ◽  
...  

Science ◽  
2019 ◽  
Vol 365 (6448) ◽  
pp. eaaw4912 ◽  
Author(s):  
Richard T. Timms ◽  
Zhiqian Zhang ◽  
David Y. Rhee ◽  
J. Wade Harper ◽  
Itay Koren ◽  
...  

The N-terminal residue influences protein stability through N-degron pathways. We used stability profiling of the human N-terminome to uncover multiple additional features of N-degron pathways. In addition to uncovering extended specificities of UBR E3 ligases, we characterized two related Cullin-RING E3 ligase complexes, Cul2ZYG11B and Cul2ZER1, that act redundantly to target N-terminal glycine. N-terminal glycine degrons are depleted at native N-termini but strongly enriched at caspase cleavage sites, suggesting roles for the substrate adaptors ZYG11B and ZER1 in protein degradation during apoptosis. Furthermore, ZYG11B and ZER1 were found to participate in the quality control of N-myristoylated proteins, in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation. Thus, an additional N-degron pathway specific for glycine regulates the stability of metazoan proteomes.


2019 ◽  
Vol 367 ◽  
pp. 599-606 ◽  
Author(s):  
Sudhakar Srivastava ◽  
V.S. Pathare ◽  
Suvarna Sounderajan ◽  
P. Suprasanna

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Ryan J. Lumpkin ◽  
Richard W. Baker ◽  
Andres E. Leschziner ◽  
Elizabeth A. Komives

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