scholarly journals Genetic Diversity and Genome-Wide Association Study of Major Ear Quantitative Traits Using High-Density SNPs in Maize

2018 ◽  
Vol 9 ◽  
Author(s):  
Xiao-Mei Zhu ◽  
Xiao-Yu Shao ◽  
Yu-He Pei ◽  
Xin-Mei Guo ◽  
Jun Li ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Association Study ◽  
Quantitative Traits ◽  
Genome Wide Association Study ◽  
High Density ◽  
Genome Wide Association ◽  
Genome Wide

scholarly journals Novel genes identified in a high-density genome wide association study for nicotine dependence

2006 ◽  
Vol 16 (1) ◽  
pp. 24-35 ◽  
Author(s):  
Laura Jean Bierut ◽  
Pamela A.F. Madden ◽  
Naomi Breslau ◽  
Eric O. Johnson ◽  
Dorothy Hatsukami ◽  
...  
Keyword(s):  
Association Study ◽  
Nicotine Dependence ◽  
Genome Wide Association Study ◽  
High Density ◽  
Genome Wide Association ◽  
Novel Genes ◽  
Genome Wide

scholarly journals Genetic Diversity and Genome Wide Association Study of β-Glucan Content in Tetraploid Wheat Grains

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0152590 ◽  
Author(s):  
Ilaria Marcotuli ◽  
Kelly Houston ◽  
Julian G. Schwerdt ◽  
Robbie Waugh ◽  
Geoffrey B. Fincher ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Tetraploid Wheat ◽  
Genome Wide Association ◽  
Wheat Grains ◽  
Genome Wide

scholarly journals Genotyping-by-sequencing and genome-wide association study reveal genetic diversity and loci controlling agronomic traits in triticale

2021 ◽  
Author(s):  
Dong Cao ◽  
Dongxia Wang ◽  
Shiming Li ◽  
Yun Li ◽  
Ming Hao ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Agronomic Traits ◽  
Genotyping By Sequencing ◽  
Genome Wide Association ◽  
Energy Crop ◽  
Hexaploid Triticale ◽  
Genome Wide ◽  
Genetic Mechanisms

Abstract Key message The genetic diversity and loci underlying agronomic traits were analysed by the reads coverage and genome-wide association study based genotyping-by-sequencing in a diverse population consisting of 199 accessions.Abstract Triticale (×Triticosecale Wittmack) is an economically important grain-forage and energy crop planted worldwide for its high biomass. Little is known about the genetic diversity and loci underlying agronomic traits in triticale. We performed genotyping-by-sequencing of 199 cultivars and mapped reads to the A, B, D, and R genomes for karyotype analysis. These cultivars could mostly be grouped into five types. Some chromosome abnormalities occurred with high frequency, such as 2D (2R) substitution, deletion of the long arm of chromosome 2D or the short arm of 5R, and translocation of the long arms of 7D/7A, the short arms of 6D/6A, or the long arms of 1D/1A. We chose only widely planted hexaploid triticale cultivars (153) for genome-wide association study. These cultivars could be divided into nine distinct groups, and the linkage disequilibrium decay was 25.4 kb in this population. We identified 253 significant marker-trait associations (MTAs) on 20 chromosomes, except 7R. Twenty-one reliable MTAs were identified repeatedly over two environments. We predicted 16 putative candidate genes involved in plant growth and development using the genome sequences of wheat and rye. These results provide a basis for understanding the genetic mechanisms of agronomic traits and will benefit the breeding of improved hexaploid triticale.

scholarly journals Genome-Wide Association Study Reveals Genetic Architecture of Septoria Tritici Blotch Resistance in a Historic Landrace Collection

2021 ◽  
Author(s):  
Anik Dutta ◽  
Daniel Croll ◽  
Bruce A. McDonald ◽  
Simon G. Krattinger
Keyword(s):  
Genetic Diversity ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Phenotypic Variability ◽  
Genome Wide Association ◽  
Septoria Tritici Blotch ◽  
Septoria Tritici ◽  
Genome Wide ◽  
A Genome ◽  
Wheat Landraces

Abstract Septoria tritici blotch (STB), caused by the fungus Zymoseptoria tritici, is a major constraint in global wheat production. The lack of genetic diversity in modern elite wheat cultivars largely hinders the improvement of STB resistance. Wheat landraces are reservoirs of untapped genetic diversity, which can be exploited to find novel STB resistance genes or alleles. Here, we characterized 188 Swiss wheat landraces for resistance to STB using four Swiss Z. tritici isolates. We used a genome-wide association study (GWAS) to identify genetic variants associated with the amount of lesion and pycnidia production by the fungus. The majority of the landraces were highly resistant for both traits to the isolate 1E4, indicating a gene-for-gene relationship, while higher phenotypic variability was observed against other isolates. GWAS detected a significant SNP on chromosome 3A that was associated with both traits in the isolate 1E4. The resistance response against 1E4 was likely controlled by the Stb6 gene. Sanger sequencing revealed that the majority of these ~100-year-old landraces carry the Stb6 resistance allele. This indicates the importance of this gene in Switzerland during the early 1900s for disease control in the field. Our study demonstrates the importance of characterizing historic landrace collections for STB resistance to provide valuable information on resistance variability and contributing alleles. This will help breeders in the future to make decisions on integrating such germplasms in STB resistance breeding.

scholarly journals Genetic Diversity and Genome-Wide Association Study of Seed Aspect Ratio Using a High-Density SNP Array in Peanut (Arachis hypogaea L.)

Genes ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 2
Author(s):  
Kunyan Zou ◽  
Ki-Seung Kim ◽  
Kipoong Kim ◽  
Dongwoo Kang ◽  
Yu-Hyeon Park ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Aspect Ratio ◽  
Association Study ◽  
Arachis Hypogaea ◽  
Genome Wide Association Study ◽  
Snp Array ◽  
The United States ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Arachis Hypogaea L

Peanut (Arachis hypogaea L.) is one of the important oil crops of the world. In this study, we aimed to evaluate the genetic diversity of 384 peanut germplasms including 100 Korean germplasms and 284 core collections from the United States Department of Agriculture (USDA) using an Axiom_Arachis array with 58K single-nucleotide polymorphisms (SNPs). We evaluated the evolutionary relationships among 384 peanut germplasms using a genome-wide association study (GWAS) of seed aspect ratio data processed by ImageJ software. In total, 14,030 filtered polymorphic SNPs were identified from the peanut 58K SNP array. We identified five SNPs with significant associations to seed aspect ratio on chromosomes Aradu.A09, Aradu.A10, Araip.B08, and Araip.B09. AX-177640219 on chromosome Araip.B08 was the most significantly associated marker in GAPIT and Regularization method. Phosphoenolpyruvate carboxylase (PEPC) was found among the eleven genes within a linkage disequilibrium (LD) of the significant SNPs on Araip.B08 and could have a strong causal effect in determining seed aspect ratio. The results of the present study provide information and methods that are useful for further genetic and genomic studies as well as molecular breeding programs in peanuts.

scholarly journals Genome-Wide Association Study of Seed Folate Content in Common Bean

2021 ◽  
Vol 12 ◽  
Author(s):  
C. Joe Martin ◽  
Davoud Torkamaneh ◽  
Muhammad Arif ◽  
Karl Peter Pauls
Keyword(s):  
Genetic Diversity ◽  
Molecular Markers ◽  
Association Study ◽  
Common Bean ◽  
Genome Wide Association Study ◽  
Folate Deficiency ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome ◽  
Essential Components

Plant-derived folates (Vitamin B9) are essential components of the human diet. They provide one-carbon units that are required for the synthesis of nucleic acids and proteins, and folate deficiency is associated with numerous adverse health conditions. The development of high-folate cultivars of common bean (Phaseolus vulgaris L.) and other staple crops is an important tool to combat folate deficiency. A population of 96 P. vulgaris accessions, representing major North American market classes, was grown in 2 years in Ontario, Canada. The population was genotyped for 5,361 molecular markers with an Illumina Infinium platform. Total folate was extracted from mature seeds using the tri-enzyme extraction method and quantified based on a microbiological assay with Lactobacillus rhamnosus. Significant genetic diversity for folate content was observed among the population in both years of study, and folate content had a range 113–222 μg per 100 g of seeds. Quantitative trait loci (QTL) for seed folate content were identified based on a genome-wide association study (GWAS). Six QTL were identified on Chr. 4, 6, 8, and 11, with three in each year of field trials. Both QTL on Chr. 11 occurred in genomic regions that were syntenic to seed folate QTL detected in previous work with P. vulgaris, Z. mays, and O. sativa. Candidate genes were identified for these QTL that might be targets for the development of molecular markers for selecting P. vulgaris cultivars with improved seed folate content. This work reports the largest survey of genetic diversity for seed folate content in P. vulgaris and identified several genotypes, including SCN4, Bat 93, OAC Redstar, and Pompadour 1014, that would be useful for breeding beans with higher than average folate levels.

A genome wide association study between CNVs and quantitative traits in Brown Swiss cattle

2017 ◽  
Vol 202 ◽  
pp. 7-12 ◽  
Author(s):  
R.T.M.M. Prinsen ◽  
A. Rossoni ◽  
B. Gredler ◽  
A. Bieber ◽  
A. Bagnato ◽  
...  
Keyword(s):  
Association Study ◽  
Quantitative Traits ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Brown Swiss ◽  
Genome Wide ◽  
A Genome ◽  
Brown Swiss Cattle
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