scholarly journals Molecular Cloning and Functional Analysis of Squalene Synthase 2(SQS2) in Salvia miltiorrhiza Bunge

2016 ◽  
Vol 7 ◽  
Author(s):  
Qixian Rong ◽  
Dan Jiang ◽  
Yijun Chen ◽  
Ye Shen ◽  
Qingjun Yuan ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Molecular Cloning ◽  
Salvia Miltiorrhiza ◽  
Squalene Synthase ◽  
Salvia Miltiorrhiza Bunge

scholarly journals Molecular Cloning and Functional Analysis of the Promoter of the Human Squalene Synthase Gene

1995 ◽  
Vol 270 (37) ◽  
pp. 21958-21965 ◽  
Author(s):  
Guimin Guan ◽  
Guojian Jiang ◽  
Rebecca L. Koch ◽  
Ishaiahu Shechter
Keyword(s):  
Functional Analysis ◽  
Molecular Cloning ◽  
Squalene Synthase ◽  
Human Squalene Synthase

Growth Characteristics and Functional Analysis of Salvia miltiorrhiza Bunge by Artificial Light Sources

2020 ◽  
Vol 28 (3) ◽  
pp. 200-208
Author(s):  
Hye Lim Choi ◽  
Ji Won Seo ◽  
Myeong Ha Hwang ◽  
Hwa Il Lee ◽  
Myong Jo Kim ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Salvia Miltiorrhiza ◽  
Growth Characteristics ◽  
Artificial Light ◽  
Light Sources ◽  
Salvia Miltiorrhiza Bunge

Molecular cloning and functional analysis of squalene synthase (SS) in Panax notoginseng

2017 ◽  
Vol 95 ◽  
pp. 658-666 ◽  
Author(s):  
Dan Jiang ◽  
Qixian Rong ◽  
Yijun Chen ◽  
Qingjun Yuan ◽  
Ye Shen ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Molecular Cloning ◽  
Panax Notoginseng ◽  
Squalene Synthase

Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

2020 ◽  
Vol 20 (28) ◽  
pp. 2520-2534
Author(s):  
He Huang ◽  
Chuanjun Song ◽  
Junbiao Chang
Keyword(s):  
Biological Activity ◽  
Herbal Medicine ◽  
Chemical Synthesis ◽  
Bioactive Compounds ◽  
Chinese Herbal Medicine ◽  
Salvia Miltiorrhiza ◽  
Salvia Miltiorrhiza Bunge ◽  
Chinese Herbal ◽  
Patent Review

: Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

scholarly journals Network Biology Approach to Identify the Active Ingredients, Potential Targets, and Signaling Pathways in Phellinus Baumii and Salvia Miltiorrhiza Bunge on Vascular Health (P15-025-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yeni Lim ◽  
Oran Kwon
Keyword(s):  
Clinical Trial ◽  
Signaling Pathways ◽  
Platelet Activation ◽  
Vascular Dysfunction ◽  
Salvia Miltiorrhiza ◽  
Network Biology ◽  
Vascular Health ◽  
Salvia Miltiorrhiza Bunge ◽  
Phellinus Baumii ◽  
Target Molecules

Abstract Objectives Increasing attention has been paid to a range of botanical food supplement that help to maintain vascular health. Multiple components in botanical foods are expected to be working in concert with various targets. In a previous our animal study, Phellinus baumii and Salvia miltiorrhiza Bunge (PS) ameliorated endothelial and vascular dysfunction in a platelet activation rat model. This study aimed to provide the components, target molecules, phenotypes, signaling pathways, and investigate the mechanism of PS on vascular health. Methods Network biology analysis was based on the data from two clinical trials. The first clinical trial was performed in healthy subjects using high-fat-induced vascular dysfunction model. The second clinical trial was performed in healthy smokers. Differential markers obtained from clinical data, Affymetrix microarray, metabolomics, together with ingredient of PS, were mapped onto the network platform termed the context-oriented directed associations. A network of “component-target-phenotype-pathway” was constructed. Results The resulting vascular health network demonstrates that the components of PS are linked various target molecules for adhesion molecule production, platelet activation, endothelial inflammation, vascular dilation, and mitochondrial metabolism and detoxification, implicated with various metabolic pathways. Conclusions Using network biology methods, this study revealed the components and their target molecules, phenotypes, signaling pathways and provided wider information to support the synergistic mechanisms of PS on vascular health. Funding Sources This research was funded by the Bio & Medical Technology Development Program of the National Research Foundation funded by the Ministry of Science & ICT and the BK21PLUS of the National Research Foundation.

Molecular cloning and functional analysis of GbRVd, a gene in Gossypium barbadense that plays an important role in conferring resistance to Verticillium wilt

Gene ◽  
2016 ◽  
Vol 575 (2) ◽  
pp. 687-694 ◽  
Author(s):  
Jun Yang ◽  
Qing Ma ◽  
Yan Zhang ◽  
Xingfen Wang ◽  
Guiyin Zhang ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Molecular Cloning ◽  
Verticillium Wilt ◽  
Gossypium Barbadense
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