scholarly journals Quantitative proteomics reveals the effect of protein glycosylation in soybean root under flooding stress

2014 ◽  
Vol 5 ◽  
Author(s):  
Ghazala Mustafa ◽  
Setsuko Komatsu
Keyword(s):  
Quantitative Proteomics ◽  
Protein Glycosylation ◽  
Soybean Root ◽  
Flooding Stress

Proteomic analysis reveals the effects of melatonin on soybean root tips under flooding stress

2021 ◽  
Vol 232 ◽  
pp. 104064
Author(s):  
Xin Wang ◽  
Fang Li ◽  
Zhenyuan Chen ◽  
Bingxian Yang ◽  
Setsuko Komatsu ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Root Tips ◽  
Soybean Root ◽  
Flooding Stress

Phosphoproteomics Reveals the Effect of Ethylene in Soybean Root under Flooding Stress

2014 ◽  
Vol 13 (12) ◽  
pp. 5618-5634 ◽  
Author(s):  
Xiaojian Yin ◽  
Katsumi Sakata ◽  
Setsuko Komatsu
Keyword(s):  
Soybean Root ◽  
Flooding Stress

scholarly journals N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity

2020 ◽  
Vol 21 (15) ◽  
pp. 5522 ◽  
Author(s):  
Martina Pirro ◽  
Yassene Mohammed ◽  
Sandra J. van Vliet ◽  
Yoann Rombouts ◽  
Agnese Sciacca ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Lines ◽  
Quantitative Proteomics ◽  
Transcriptional Factor ◽  
Protein Glycosylation ◽  
Promising Tool ◽  
Colorectal Cancer Cell Lines ◽  
Advanced Stages ◽  
Type C ◽  
The Impact

Colorectal cancer (CRC) is the second-leading cause of cancer death worldwide due in part to a high proportion of patients diagnosed at advanced stages of the disease. For this reason, many efforts have been made towards new approaches for early detection and prognosis. Cancer-associated aberrant glycosylation, especially the Tn and STn antigens, can be detected using the macrophage galactose-type C-type lectin (MGL/CLEC10A/CD301), which has been shown to be a promising tool for CRC prognosis. We had recently identified the major MGL-binding glycoproteins in two high-MGL-binding CRC cells lines, HCT116 and HT29. However, we failed to detect the presence of O-linked Tn and STn glycans on most CRC glycoproteins recognized by MGL. We therefore investigated here the impact of N-linked and O-linked glycans carried by these proteins for the binding to MGL. In addition, we performed quantitative proteomics to study the major differences in proteins involved in glycosylation in these cells. Our results showed that N-glycans have a significant, previously underestimated, importance in MGL binding to CRC cell lines. Finally, we highlighted both common and cell-specific processes associated with a high-MGL-binding phenotype, such as differential levels of enzymes involved in protein glycosylation, and a transcriptional factor (CDX-2) involved in their regulation.

Proteomic and Metabolomic Analyses of Soybean Root Tips Under Flooding Stress

2014 ◽  
Vol 21 (9) ◽  
pp. 865-884 ◽  
Author(s):  
Setsuko Komatsu ◽  
Takuji Nakamura ◽  
Yurie Sugimoto ◽  
Kazunori Sakamoto
Keyword(s):  
Root Tips ◽  
Soybean Root ◽  
Flooding Stress
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