scholarly journals The induction of stromule formation by a plant DNA-virus in epidermal leaf tissues suggests a novel intra- and intercellular macromolecular trafficking route

2012 ◽  
Vol 3 ◽  
Author(s):  
Björn Krenz ◽  
Holger Jeske ◽  
Tatjana Kleinow
Keyword(s):  
Dna Virus ◽  
Plant Dna ◽  
Macromolecular Trafficking ◽  
Leaf Tissues

scholarly journals A plant DNA virus replicates in the salivary glands of its insect vector via recruitment of host DNA synthesis machinery

2020 ◽  
Vol 117 (29) ◽  
pp. 16928-16937 ◽  
Author(s):  
Ya-Zhou He ◽  
Yu-Meng Wang ◽  
Tian-Yan Yin ◽  
Elvira Fiallo-Olivé ◽  
Yin-Quan Liu ◽  
...  
Keyword(s):  
Dna Synthesis ◽  
Salivary Glands ◽  
Large Family ◽  
Plant Viruses ◽  
Nuclear Antigen ◽  
Insect Vector ◽  
Dna Virus ◽  
Dna Viruses ◽  
Plant Dna ◽  
Leaf Curl

Whereas most of the arthropod-borne animal viruses replicate in their vectors, this is less common for plant viruses. So far, only some plant RNA viruses have been demonstrated to replicate in insect vectors and plant hosts. How plant viruses evolved to replicate in the animal kingdom remains largely unknown. Geminiviruses comprise a large family of plant-infecting, single-stranded DNA viruses that cause serious crop losses worldwide. Here, we report evidence and insight into the replication of the geminivirus tomato yellow leaf curl virus (TYLCV) in the whitefly (Bemisia tabaci) vector and that replication is mainly in the salivary glands. We found that TYLCV induces DNA synthesis machinery, proliferating cell nuclear antigen (PCNA) and DNA polymerase δ (Polδ), to establish a replication-competent environment in whiteflies. TYLCV replication-associated protein (Rep) interacts with whitefly PCNA, which recruits DNA Polδ for virus replication. In contrast, another geminivirus, papaya leaf curl China virus (PaLCuCNV), does not replicate in the whitefly vector. PaLCuCNV does not induce DNA-synthesis machinery, and the Rep does not interact with whitefly PCNA. Our findings reveal important mechanisms by which a plant DNA virus replicates across the kingdom barrier in an insect and may help to explain the global spread of this devastating pathogen.

Two proteins of a plant DNA virus coordinate nuclear and plasmodesmal transport

Cell ◽  
1994 ◽  
Vol 76 (5) ◽  
pp. 925-932 ◽  
Author(s):  
Amine O. Noueiry ◽  
William J. Lucas ◽  
Robert L. Gilbertson
Keyword(s):  
Dna Virus ◽  
Plant Dna

scholarly journals Suppression of RNA Silencing by a Plant DNA Virus Satellite Requires a Host Calmodulin-Like Protein to Repress RDR6 Expression

2014 ◽  
Vol 10 (2) ◽  
pp. e1003921 ◽  
Author(s):  
Fangfang Li ◽  
Changjun Huang ◽  
Zhenghe Li ◽  
Xueping Zhou
Keyword(s):  
Rna Silencing ◽  
Dna Virus ◽  
Plant Dna

scholarly journals Inhibition of DNA Replication of Human Papillomavirus by Artificial Zinc Finger Proteins

2006 ◽  
Vol 80 (11) ◽  
pp. 5405-5412 ◽  
Author(s):  
Takashi Mino ◽  
Takeaki Hatono ◽  
Naoki Matsumoto ◽  
Tomoaki Mori ◽  
Yusuke Mineta ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Dna Replication ◽  
Zinc Finger ◽  
Mammalian Cells ◽  
Replication Origin ◽  
Zinc Finger Protein ◽  
Dna Virus ◽  
Dna Viruses ◽  
Plant Dna ◽  
Hpv 18

ABSTRACT Recently, we demonstrated that plant DNA virus replication was inhibited in planta by using an artificial zinc finger protein (AZP) and created AZP-based transgenic plants resistant to DNA virus infection. Here we apply the AZP technology to the inhibition of replication of a mammalian DNA virus, human papillomavirus type 18 (HPV-18). Two AZPs, designated AZPHPV-1 and AZPHPV-2, were designed by using our nondegenerate recognition code table and were constructed to block binding of the HPV-18 E2 replication protein to the replication origin. Both of the newly designed AZPs had much higher affinities towards the replication origin than did the E2 protein, and they efficiently blocked E2 binding in vitro. In transient replication assays, both AZPs inhibited viral DNA replication, especially AZPHPV-2, which reduced the replication level to approximately 10%. We also demonstrated in transient replication assays, using plasmids with mutant replication origins, that AZPHPV-2 could precisely recognize the replication origin in mammalian cells. Thus, it was demonstrated that the AZP technology could be applied not only to plant DNA viruses but also to mammalian DNA viruses.

Plant DNA Virus Diseases

2004 ◽  
pp. 960-964 ◽  
Author(s):  
Robert L. Gilbertson ◽  
Maria R. Rojas
Keyword(s):  
Virus Diseases ◽  
Dna Virus ◽  
Plant Dna

Intergeneric transmission of a marine plant DNA virus

1992 ◽  
Vol 79 (1) ◽  
pp. 37-39 ◽  
Author(s):  
D. G. M�ller
Keyword(s):  
Dna Virus ◽  
Plant Dna ◽  
Marine Plant
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