scholarly journals Strength Training Volume to Increase Muscle Mass Responsiveness in Older Individuals: Weekly Sets Based Approach

2021 ◽  
Vol 12 ◽  
Author(s):  
Davi Alves de Santana ◽  
Alex Castro ◽  
Cláudia Regina Cavaglieri
Keyword(s):  
Strength Training ◽  
Muscle Mass ◽  
Training Volume ◽  
Older Individuals ◽  
Increase Muscle Mass

Supplementation with beta-hydroxy-beta-methylbutyrate impacts glucose homeostasis and increases liver size in trained mice

2020 ◽  
Vol 90 (1-2) ◽  
pp. 113-123
Author(s):  
Ines Schadock ◽  
Barbara G. Freitas ◽  
Irae L. Moreira ◽  
Joao A. Rincon ◽  
Marcio Nunes Correa ◽  
...  
Keyword(s):  
Strength Training ◽  
Muscle Mass ◽  
Glucose Homeostasis ◽  
Fasting Blood Glucose ◽  
Hepatic Metabolism ◽  
Mass Gain ◽  
Trained Group ◽  
Tissue Mass ◽  
Liver Size ◽  
Intensive Training

Abstract. β-hydroxy-β-methyl butyrate (HMB) is a bioactive metabolite derived from the amino acid leucine, usually applied for muscle mass increase during physical training, as well as for muscle mass maintenance in debilitating chronic diseases. The hypothesis of the present study is that HMB is a safe supplement for muscle mass gain by strength training. Based on this, the objective was to measure changes in body composition, glucose homeostasis and hepatic metabolism of HMB supplemented mice during strength training. Two of four groups of male mice (n = 6/group) underwent an 8-week training period session (climbing stairs) with or without HMB supplementation (190 mg/kgBW per day). We observed lower body mass gain (4.9 ± 0.43% versus 1.2 ± 0.43, p < 0.001) and increased liver mass (40.9 ± 0.9 mg/gBW versus 44.8 ± 1.3, p < 0.001) in the supplemented trained group compared with the non-supplemented groups. The supplemented trained group had an increase in relative adipose tissue mass (12.4 ± 0.63 mg/gBW versus 16.1 ± 0.88, P < 0.01) compared to the non-supplemented untrained group, and an increase in fasting blood glucose (111 ± 4.58 mg/dL versus 122 ± 3.70, P < 0.05) and insulin resistance (3.79 ± 0.19 % glucose decay/min versus 2.45 ± 0.28, P < 0.05) comparing with non-supplemented trained group. Adaptive heart hypertrophy was observed only in the non-supplemented trained group (4.82 ± 0.05 mg/gBW versus 5.12 ± 0.13, P < 0.05). There was a higher hepatic insulin-like growth factor-1 expression (P = 0.002) in supplemented untrained comparing with non-supplemented untrained group. Gene expression of gluconeogenesis regulatory factors was increased by training and reduced by HMB supplementation. These results confirm that HMB supplementation associated with intensive training protocol drives changes in glucose homeostasis and liver metabolism in mice.

Anodal transcranial direct current stimulation enhances strength training volume but not the force–velocity profile

2020 ◽  
Vol 120 (8) ◽  
pp. 1881-1891 ◽  
Author(s):  
Carlos Alix-Fages ◽  
Amador García-Ramos ◽  
Giancarlo Calderón-Nadal ◽  
David Colomer-Poveda ◽  
Salvador Romero-Arenas ◽  
...  
Keyword(s):  
Velocity Profile ◽  
Strength Training ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Training Volume ◽  
Direct Current Stimulation ◽  
Force Velocity

MO612THE ROLE OF MECHANICAL MUSCLE POWER IN PHYSICAL DYSFUNCTION: A MODEL FOR TAILORING RESISTANCE-BASED REHABILITATION IN CHRONIC KIDNEY DISEASE

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Thomas Wilkinson ◽  
Eleanor Gore ◽  
Jared Palmer ◽  
Luke Baker ◽  
Emma Watson ◽  
...  
Keyword(s):  
Activities Of Daily Living ◽  
Strength Training ◽  
Physical Function ◽  
Muscle Mass ◽  
Gait Speed ◽  
Daily Living ◽  
Muscle Power ◽  
Mechanical Power ◽  
Relative Power

Abstract Background and Aims Individuals living with CKD are characterised by adverse changes in physical function. Knowledge of the factors that mediate impairments in physical functioning is crucial for developing effective interventions that preserve mobility and future independence. Mechanical muscle power describes the rate of performing work and is the product of muscular force and velocity of contraction. Muscle power has been shown to have stronger associations with functional limitations and mortality than sarcopenia in older adults. In CKD, the role of mechanical muscle power is poorly understood and is overlooked as a target in many rehabilitation programmes, often at the expense of muscle mass or strength. The aims of this study were to 1) explore the prevalence of low absolute mechanical power, low relative mechanical power, and low specific mechanical power in CKD; and 2) investigate the association of mechanical power with the ability to complete activities of daily living and physical performance. Method Mechanical muscle power (relative, allometric, specific) was calculated using the sit-to-stand-5 (STS5) test as per previously validated equations. Legs lean mass was derived from regional analyses conducted using bioelectrical impedance analysis (BIA). Physical performance was assessed using two objective tests: usual gait speed and the ‘time-up-and-go’ (TUAG) test. Self-reported activities of daily living (ADLs) were assessed via the Duke Activity Status Index (DASI). Balance and postural stability (postural sway and velocity) was assessed using a FysioMeter. Sex-specific tertiles were used to determine low, medium and high levels of relative STS power and its main components. Results 102 participants with non-dialysis CKD were included (mean age: 62.0 (±14.1) years, n=49 males (48%), mean eGFR: 38.0 (±21.5) ml.min.1.73m2). The mean estimated relative power was 3.1 (±1.5) W.kg in females and 3.3 (±1.3) W.kg in males. Low relative power was found in 35/102 (34%) patients. Relative power was a significant independent predictor of self-reported ADLs (via the DASI) (B=.413, P=.004), and performance on the TUAG (B=-.719, P&lt;.001) and gait speed (B=.404, P=.003) tests. Skeletal muscle mass was not associated with the DASI or any of the objective function tests Conclusion Patients presenting with low muscle power would benefit from participation in appropriate interventions designed to improve the physiological components accounting for low relative muscle power. Assessment of power can be used to tailor renal rehabilitation programmes as shown in Figure 1. Incorporation of power-based training, a novel type of strength training, designed by manipulating traditional strength training variables and primarily movement velocity and training intensity may present the best strategy for improving physical function in CKD.

G.P.3.11 Novel myostatin inhibitors increase muscle mass in wild-type and mdx mice

2007 ◽  
Vol 17 (9-10) ◽  
pp. 785 ◽  
Author(s):  
J. Lachey ◽  
A. Pullen ◽  
R. Pearsall ◽  
J. Seehra
Keyword(s):  
Muscle Mass ◽  
Mdx Mice ◽  
Wild Type ◽  
Increase Muscle Mass

scholarly journals What Is the Optimal Strength Training Load to Improve Swimming Performance? A Randomized Trial of Male Competitive Swimmers

2021 ◽  
Vol 18 (22) ◽  
pp. 11770
Author(s):  
Sofiene Amara ◽  
Emmet Crowley ◽  
Senda Sammoud ◽  
Yassine Negra ◽  
Raouf Hammami ◽  
...  
Keyword(s):  
Resistance Training ◽  
Strength Training ◽  
Bench Press ◽  
Swimming Performance ◽  
Training Volume ◽  
Front Crawl ◽  
Leg Extension ◽  
Low Resistance ◽  
Volume Load ◽  
Competitive Swimmers

This study aimed to compare the effectiveness of high, moderate, and low resistance training volume-load of maximum strength training on muscle strength and swimming performance in competitive swimmers. Thirty-three male swimmers were randomly allocated to high (age = 16.5 ± 0.30 years), moderate (age = 16.1 ± 0.32 years) and a low resistance training volume-load group (age = 15.9 ± 0.31). This study was carried out in mid-season (January to March). Pre and post strength (e.g., repetition maximum [1RM] leg extension and bench press tests), swimming (25, 50 m front-crawl), start (speed, time, distance) and turn (time of turn) performance tests were conducted. Our findings revealed a large main effect of time for 1RM bench press: d = 1.38; 1RM leg extension: d = 1.55, and for 25 (d = 1.12), and 50 m (d = 1.97) front-crawl, similarly for start and turn performance (d = 1.28–1.46). However, no significant Group × Time interactions were shown in all strength swimming performances, start and turn tests (p > 0.05). In conclusion, low training loads have been shown to elicit the same results as moderate, and high training loads protocol. Therefore, this study shows evidence that the addition of low training volume-loads as a regular part of a maximal strength training regime will elicit improvements in strength and swimming performance.

Free leucine supplementation during an 8-week resistance training program does not increase muscle mass and strength in untrained young adult subjects

Amino Acids ◽  
2017 ◽  
Vol 49 (7) ◽  
pp. 1255-1262 ◽  
Author(s):  
Andreo Fernando Aguiar ◽  
Alan Pablo Grala ◽  
Rubens Alexandre da Silva ◽  
Lúcio Flávio Soares-Caldeira ◽  
Francis Lopes Pacagnelli ◽  
...  
Keyword(s):  
Young Adult ◽  
Resistance Training ◽  
Training Program ◽  
Muscle Mass ◽  
Leucine Supplementation ◽  
Resistance Training Program ◽  
Increase Muscle Mass

scholarly journals Use of alfacalcidol in osteoporotic patients with low muscle mass might increase muscle mass: An investigation using a patient database

2014 ◽  
Vol 14 ◽  
pp. 122-128 ◽  
Author(s):  
Sadayuki Ito ◽  
Atsushi Harada ◽  
Takehiro Kasai ◽  
Yoshihito Sakai ◽  
Marie Takemura ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Increase Muscle Mass ◽  
Patient Database

Regional Differences in the Diagnosis of Sarcopenia in Older People in Brazil

2021 ◽  
Vol 7 (4) ◽  
Author(s):  
Menezes JM ◽  
◽  
Paes AT ◽  
Frisoli-Junior A ◽  
◽  
...  
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Older Individuals ◽  
International Consensus ◽  
Cross Sectional ◽  
Cutoff Values ◽  
Elderly Outpatients ◽  
Consensus Values ◽  
Aging Muscle ◽  
Sectional Analysis

Introduction: Sarcopenia is a prevalent condition, and that is strongly associated with morbimortality outcomes. The optimal way to diagnose sarcopenia is currently a matter of debate. Despite evidence suggesting differences in body composition and physical performance of individuals from different regions, the diagnosis of sarcopenia in Brazil is still conducted using cutoff values established by international consensus. Therefore, the objective of this study was to establish cutoff values for appendicular muscle mass and muscle strength in a population of elderly outpatients with cardiovascular diseases from the city of São Paulo, using this data to compare populations with sarcopenia diagnosed in Brazil with individuals diagnosed using the European consensus values. Materials and Methods: This was a cross-sectional analysis including 502 older individuals from the SARCOS-Brazil study. All subjects underwent densitometry to assess muscle mass and measure strength using a manual dynamometer. The cutoff values for the SARCOS-Brazil criteria were obtained from the 25th percentile of each variable. Results and Discussion: There was no difference in the prevalence of muscle weakness using the two methods (180 patients, 35.9% of the sample). However, a difference was observed concerning low muscle mass. According to the European criteria, a total of 215 older individuals (42.8%) had low muscle mass and 123 (24.5%) according to the SARCOS-Brazil criteria. The prevalence of sarcopenia was 20.3% according to European criteria versus 13.7% according to the SARCOS-Brazil criteria. The kappa coefficient was 0.79. Conclusion: This study suggests that weakness and muscle mass can, in isolation, predict variables related to past vulnerability outcomes, as well as highlights the possibility of using regional cutoff values for the diagnosis of sarcopenia. Keywords: Sarcopenia; Aging; Muscle mass; Muscle strength

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