scholarly journals The Dose Response of Taurine on Aerobic and Strength Exercises: A Systematic Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Qi Chen ◽  
Zheng Li ◽  
Ricardo A. Pinho ◽  
Ramesh C. Gupta ◽  
Ukadike C. Ugbolue ◽  
...  

Taurine is a naturally occurring amino acid involved in various functions, including regulating ion channels, cell volume, and membrane stabilization. However, how this molecule orchestrates such functions is unknown, particularly the dose response in exercised muscles. Therefore, this review aimed to systematically review the dose response of taurine on both aerobic and strength exercise performance. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, relevant articles were sought on PubMed, Medline, Web of Science, and Google Scholar using related terms, including taurine, exercise performance, exercise, muscle, physical training, running, strength, endurance exercise, resistance exercise, aerobic exercise, and swimming. Ten articles were retrieved, reviewed, and subjected to systematic analysis. The following parameters were used to assess exercise performance in the selected studies: creatine kinase (CK), lactic acid dehydrogenase, carbohydrate, fat, glycerol, malondialdehyde, enzymatic antioxidants, blood pH, taurine level, and muscular strength. From the selected literature, we observed that taurine supplementation (2 g three times daily) with exercise can decrease DNA damage. Furthermore, 1 g of acute taurine administration before or after exercise can decrease lactate levels. However, acute administration of taurine (6 g) at a high dose before the start of exercise had no effect on reducing lactate level, but increased glycerol levels, suggesting that taurine could be an effective agent for prolonged activities, particularly at higher intensities. However, further studies are warranted to establish the role of taurine in fat metabolism during exercise. Finally, we observed that a low dose of taurine (0.05 g) before performing strength enhancing exercises can decrease muscular fatigue and increase enzymatic antioxidants.Systematic Review Registration:http://www.crd.york.ac.uk/PROSPERO, PROSPERO (CRD42021225243).

2018 ◽  
Vol 8 (4_suppl) ◽  
pp. 59S-67S ◽  
Author(s):  
Geoffrey Stricsek ◽  
Justin Iorio ◽  
Yusef Mosley ◽  
Srinivas Prasad ◽  
Joshua Heller ◽  
...  

Study Design: Systematic analysis and review. Objective: Evaluation of the presentation, etiology, management strategies (including both surgical and nonsurgical options), and neurological functional outcomes in patients with cervical spinal epidural abscess (SEA). Methods: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) criteria were used to create a framework based on which articles pertaining to cervical SEA were chosen for review following a search of the Ovid and PubMed databases using the search terms “epidural abscess” and “cervical.” Included studies needed to have at least 4 patients aged 18 years or older, and to have been published within the past 20 years. Results: Database searches yielded 521 potential articles in PubMed and 974 potential articles in Ovid. After review, 11 studies were ultimately identified for inclusion in this systematic review. Surgery appears to be a well-tolerated management strategy with limited complications for patients with cervical SEA. However, the quantity of data comparing medical and surgical treatment of cervical SEA is limited and the bulk of the data is derived from low quality studies. Conclusion: Data reporting was heterogeneous among studies making it difficult to draw discrete conclusions. Early surgical intervention may be appropriate in selected patients with cervical epidural abscess, but it is not clear what distinguishes these patients from those who are successfully managed nonoperatively.


2020 ◽  
Vol 32 (2) ◽  
pp. 913-933 ◽  
Author(s):  
Tanmay Sharma ◽  
Joseph Chen ◽  
Wan Yu Liu

Purpose Theoretical and empirical developments in academic literature have not been able to keep pace with the growing industry focus on eco-innovation and green hospitality practices. This paper aims to address this gap and provide an up-to-date review of research on eco-innovative practices in 13 leading hospitality journals over the past two decades, 1998-2018. Design/methodology/approach A systematic review that incorporates the preferred reporting items for systematic reviews and meta-analyses flow diagram is used to guide the data selection for this paper. The paper analyzes 403 studies published in 13 established hospitality journals to identify homogeneous research themes. Findings A unified conceptual framework is proposed by identifying seven research domains under eco-innovative practices. Even though research attention on green practices has increased in recent years, the development of conceptual frameworks, appropriate measurement scales and theoretical support for eco-innovative practices is warranted. Research limitations/implications Although the paper attempts to include as many environmentally related studies as possible, by being restricted to papers published only in 13 leading hospitality journals, it may not have drawn on all relevant eco-innovation studies in hospitality research. Originality/value To the knowledge of the authors, this is the first systematic analysis of hospitality research on eco-innovative practices that reviews such a large number (403) of studies spanning the past two decades (1998-2018). The most recent review by Kim et al. (2017) covered 146 green research studies published between 2000 and 2014; whereas, out of 403 studies reviewed in this study, 231 (57per cent) have been published between 2014 and 2018. This trend is indicative of the fast-evolving nature of sustainability research and the need for an up-to-date systematic review of recent literature in the field.


2021 ◽  
Vol 13 (16) ◽  
pp. 9047
Author(s):  
Emily John ◽  
Melor Md Yunus

The ubiquitous nature of social media (SM) makes it a very essential tool to use in the world of education, especially with the advent of the COVID-19 pandemic which has led to a paradigm shift in the approaches used in the teaching and learning of English language skills. This review focuses on the use of social media as a medium of instruction to aid the acquisition of speaking skills, which many learners find extremely challenging and inhibiting. Thus, this systematic review investigates the integration of social media in the teaching and learning of speaking skills. To ensure the systematic analysis of the selected articles, Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) 2020 guidelines were utilized. A total of 36 peer-reviewed journal articles from the year 2016 to 2021 were accessed from two databases: ERIC and Google Scholar. Prior to the start of the review, an inclusion and exclusion criteria selection process was conducted to ensure the focus of the review. Overall, the articles reviewed presented the claim that the integration of social media is seen as a positive inclusion for the teaching of speaking skills using various social media applications. Findings reveal that there are improvements in speaking skills, as well as confidence to speak and a decline in speaking anxiety. Teachers and educators can now make use of the various social media platforms such as Telegram, Facebook, WhatsApp, and others to provide learners with more practice that is not only restricted to the classroom but has moved beyond it.


2021 ◽  
Author(s):  
Kim Boesen ◽  
Karsten Juhl Jørgensen ◽  
Peter C Gøtzsche

Objective: To assess potential dose-response relationships of extended-release methylphenidate for ADHD in adults on efficacy outcomes. Study design and setting: Post-hoc analysis based on a systematic review of extended-release methylphenidate (https://doi.org/10.1002/14651858.CD012857). Using data from clinical trials comparing multiple fixed-dose methylphenidate groups with placebo, we conducted subgroup meta-analyses for available efficacy outcomes. Results and conclusion: Five trials used a fixed-dose design with multiple methylphenidate groups receiving different doses. All trials were pivotal industry sponsored studies conducted to obtain marketing authorisation. We analysed four efficacy outcomes: Self-rated ADHD symptoms (5 trials, 1807 participants), investigator-rated ADHD symptoms (5 trials, 1904 participants), quality of life (4 trials, 1158 participants), and peer-rated ADHD symptoms (2 trials, 879 participants). There were no dose-response relationships for any outcome.


2022 ◽  
Vol 14 (2) ◽  
pp. 769
Author(s):  
Abraham Camacho-Garza ◽  
Otilio A. Acevedo-Sandoval ◽  
Elena Ma. Otazo-Sánchez ◽  
Alma D. Roman-Gutiérrez ◽  
Francisco Prieto-García

Socio-environmental conflicts are situations that exemplify human rights transgressions caused by extractive activities. These are present in developing countries where extractivism, imperialism, and colonialism paradigms prevail. In the context of Mexico, criminalization, violence, and the absence of rule of law promote these conflicts, frequently aggravated by involvement with private interests. In the last 20 years, the relationship between human rights in the mining sector and its impact on the environment has been a critical research subject. This paper aims to carry out a systematic review to analyze human rights transgressions related to the mining industry’s impact in Mexico, and identify factors causing socio-environmental conflicts. The current study shows a systematic analysis based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology. This method contributed to the collection of references that describe conflicts due to human rights transgressions and environmental damage in mining areas in Mexico. Human rights transgressions caused by mining in a Mexican context demonstrate the inability of the state to stop the increase in socio-environmental conflicts and its lack of concern towards preventing damage to the environment.


2020 ◽  
Vol 74 (5) ◽  
pp. 481-487 ◽  
Author(s):  
Sabrina Schlesinger ◽  
Manuela Neuenschwander ◽  
Aurélie Ballon ◽  
Ute Nöthlings ◽  
Janett Barbaresko

IntroductionLifestyle factors in combination have been hypothesised to be associated with the prevention of type 2 diabetes (T2D) and mortality among individuals with T2D. The aim was to conduct a systematic review and meta-analysis to quantify the association between lifestyle indices and incident T2D as well as mortality in individuals with T2D.MethodsPubMed and Web of Science were searched up to September 2019. We included prospective cohort studies investigating at least three lifestyle factors in association with T2D, or all-cause mortality in individuals with diabetes. We conducted pairwise and dose-response meta-analyses to calculate summary relative risks (SRR) by using random effects model.ResultsIn total, 19 studies were included. Adhering to a healthy lifestyle (mostly favourable diet, physical activity, non-smoking, moderate alcohol intake and normal weight) was associated with a reduced SRR of 78% for T2D (SRR: 0.22; 95% CI: 0.16 to 0.32; n=14) and 57% for mortality (SRR: 0.43; 95% CI: 0.31 to 0.58; n=5) compared with low adherence to a healthy lifestyle. In dose-response analyses, the adherence to every additional healthy lifestyle factor was associated with a reduced relative risk of 32% (95% CI: 28% to 36%) for T2D and 21% (95% CI: 15% to 26%) for mortality.ConclusionsOur findings underline the importance of the joint adherence to healthy lifestyle factors to prevent T2D and improve survival among individuals with diabetes. Adherence to every additional health lifestyle factor play a role in the T2D prevention and progression.PROSPERO registration numberCRD42018091409.


2022 ◽  
Vol 43 ◽  
pp. 101236
Author(s):  
Chunying Fu ◽  
Wenting Hao ◽  
Nipun Shrestha ◽  
Salim S. Virani ◽  
Shiva Raj Mishra ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4359
Author(s):  
Juan Mielgo-Ayuso ◽  
Laura Pietrantonio ◽  
Aitor Viribay ◽  
Julio Calleja-González ◽  
Jerónimo González-Bernal ◽  
...  

l-Carnitine (l-C) and any of its forms (glycine-propionyl l-Carnitine (GPL-C) or l-Carnitine l-tartrate (l-CLT)) has been frequently recommended as a supplement to improve sports performance due to, among others, its role in fat metabolism and in maintaining the mitochondrial acetyl-CoA/CoA ratio. The main aim of the present systematic review was to determine the effects of oral l-C supplementation on moderate- (50–79% V˙O2 max) and high-intensity (≥80% V˙O2 max) exercise performance and to show the effective doses and ideal timing of its intake. A structured search was performed according to the PRISMA® statement and the PICOS guidelines in the Web of Science (WOS) and Scopus databases, including selected data obtained up to 24 October 2021. The search included studies where l-C or glycine-propionyl l-Carnitine (GPL-C) supplementation was compared with a placebo in an identical situation and tested its effects on high and/or low–moderate performance. The trials that used the supplementation of l-C together with additional supplements were eliminated. There were no applied filters on physical fitness level, race, or age of the participants. The methodological quality of studies was evaluated by the McMaster Critical Review Form. Of the 220 articles obtained, 11 were finally included in this systematic review. Six studies used l-C, while three studies used l-CLT, and two others combined the molecule propionyl l-Carnitine (PL-C) with GPL-C. Five studies analyzed chronic supplementation (4–24 weeks) and six studies used an acute administration (<7 days). The administration doses in this chronic supplementation varied from 1 to 3 g/day; in acute supplementation, oral l-C supplementation doses ranged from 3 to 4 g. On the one hand, the effects of oral l-C supplementation on high-intensity exercise performance variables were analyzed in nine studies. Four of them measured the effects of chronic supplementation (lower rating of perceived exertion (RPE) after 30 min at 80% V˙O2 max on cycle ergometer and higher work capacity in “all-out” tests, peak power in a Wingate test, and the number of repetitions and volume lifted in leg press exercises), and five studies analyzed the effects of acute supplementation (lower RPE after graded exercise test on the treadmill until exhaustion and higher peak and average power in the Wingate cycle ergometer test). On the other hand, the effects of l-C supplementation on moderate exercise performance variables were observed in six studies. Out of those, three measured the effect of an acute supplementation, and three described the effect of a chronic supplementation, but no significant improvements on performance were found. In summary, l-C supplementation with 3 to 4 g ingested between 60 and 90 min before testing or 2 to 2.72 g/day for 9 to 24 weeks improved high-intensity exercise performance. However, chronic or acute l-C or GPL-C supplementation did not present improvements on moderate exercise performance.


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