scholarly journals Significance of Atrial and Brain Natriuretic Peptide Measurements in Fetuses With Heart Failure

2021 ◽  
Vol 12 ◽  
Author(s):  
Takekazu Miyoshi ◽  
Hiroshi Hosoda ◽  
Naoto Minamino
Keyword(s):  
Heart Failure ◽  
Brain Natriuretic Peptide ◽  
Amniotic Fluid ◽  
Congenital Heart Defect ◽  
Umbilical Cord Blood ◽  
Congenital Heart ◽  
Fetal Heart ◽  
Diagnostic Biomarker ◽  
Heart Defect ◽  
Fetal Heart Failure

Fetal heart failure is mainly caused by congenital heart defect and arrhythmia. It is difficult to appropriately diagnose the severity of fetal heart failure simply by ultrasonography because the development of a fetal heart in fetoplacental circulation and how well the fetal myocardium can adapt to postnatal cardiopulmonary circulation are challenging to assess. In adult cardiology, natriuretic peptides (NPs) are the most useful biomarker of heart failure; however, studies investigating NP levels in the fetuses and amniotic fluid are quite limited. Furthermore, little is known about their production and metabolism. This review summarized the most relevant findings on NP levels in the umbilical cord blood and amniotic fluid. The findings can then extend their use as a diagnostic biomarker of heart failure in fetuses with congenital heart defect and/or arrhythmia.

scholarly journals Atrial Fibrillation-Induced Cardiac Shock: First Manifestation of a Congenitally Corrected Transposition of the Great Arteries in a 45-Year-Old Man

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
M. Graf ◽  
M. Zaczkiewicz ◽  
J. Torzewski ◽  
O. Zimmermann
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Heart Failure ◽  
Congenital Heart Defect ◽  
Congenital Heart ◽  
Prior History ◽  
Heart Defect ◽  
Cardiac Shock ◽  
Congenitally Corrected Transposition ◽  
Corrected Transposition

Background.The congenitally corrected transposition of the great arteries (L-TGA) is a very rare congenital heart defect, which often remains undetected for several decades of life.Case Presentation.We report on a 45-year-old man without prior history of heart disease, presenting with cardiac shock related to a first episode of tachycardic atrial fibrillation. The diagnostic work-up identified a L-TGA as the underlying cause for acute heart failure.Discussion.L-TGA is a very rare congenital heart defect, which is characterized by an atrioventricular as well as a ventriculoarterial discordance. By this means, the physiological sequence of pulmonary and systemic circulation is still maintained. On the basis of an ongoing strain of the right ventricle, which has to carry the burden of the systemic blood pressure, after more than four decades without symptoms, acute heart failure was triggered by a tachycardic atrial fibrillation.

scholarly journals Maternal biomarkers for fetal heart failure in fetuses with congenital heart defects or arrhythmias

2019 ◽  
Vol 220 (1) ◽  
pp. 104.e1-104.e15 ◽  
Author(s):  
Takekazu Miyoshi ◽  
Hiroshi Hosoda ◽  
Michikazu Nakai ◽  
Kunihiro Nishimura ◽  
Mikiya Miyazato ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Fetal Heart ◽  
Heart Defects ◽  
Fetal Heart Failure

scholarly journals VP23.09: Oxidative stress biomarkers in amniotic fluid in fetuses with isolated congenital heart defect

2021 ◽  
Vol 58 (S1) ◽  
pp. 196-197
Author(s):  
J. Arraez Brito ◽  
O. Gómez ◽  
M.C. Escobar‐Diaz ◽  
E. Marimon ◽  
J. Martinez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Amniotic Fluid ◽  
Congenital Heart Defect ◽  
Congenital Heart ◽  
Oxidative Stress Biomarkers ◽  
Stress Biomarkers ◽  
Heart Defect

Novel pathological findings of placenta with fetal heart failure associated with congenital heart disease

Placenta ◽  
2015 ◽  
Vol 36 (10) ◽  
pp. A8
Author(s):  
Takekazu Miyoshi ◽  
Taka-aki Matsuyama ◽  
Atsushi Daimon ◽  
Chi-ichiro Kuwazuru ◽  
Masami Sawada ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Fetal Heart ◽  
Pathological Findings ◽  
Fetal Heart Failure

scholarly journals Fetal echocardiography - 25-year experience in Serbia

2019 ◽  
Vol 147 (1-2) ◽  
pp. 70-73
Author(s):  
Svetlana Vrzic-Petronijevic ◽  
Milos Petronijevic ◽  
Vojislav Parezanovic ◽  
Jelena Stamenkovic-Dukanac ◽  
Zorica Jestrovic ◽  
...  
Keyword(s):  
Congenital Heart Defect ◽  
Congenital Heart ◽  
Fetal Heart ◽  
Heart Diseases ◽  
Fetal Echocardiography ◽  
Heart Defects ◽  
Pathological Finding ◽  
Congenital Heart Diseases ◽  
Heart Defect ◽  
Specificity And Sensitivity

Introduction/Objective. Congenital heart diseases are the most common congenital anomalies. The objective of the study was to determine reliability, specificity, and sensitivity of fetal echocardiography in detection of congenital heart diseases in a referral center for fetal echocardiography. Methods. We analyzed 14,500 fetal echocardiography exams (FEC) between 1991 and 2014, performed in two tertiary centers. Results. The average maternal age at the time of diagnosis was 32 years. The mean gestational age at the time of diagnosis was 25.9 weeks. The most common indications for FEC were suspicious abnormal cardiac findings in obstetrical screening sonography (50.6%). Among 9,055 examined fetuses, pathological finding on the fetal heart was found in 638 cases. The most common congenital heart diseases were structural anomalies of the fetal heart in 81%, of which 13.3% were fetuses with hypoplastic left heart syndrome and 11.2% with ventricular septal defect. Of all fetuses with diagnosed congenital heart defect, 46.2% were born alive and had good postnatal prognosis, while 2.7% died in utero, and 10.6% died in the early neonatal period. Pregnancy was terminated in 40.4% of fetuses with severe congenital heart defect. Sensitivity of the diagnostic procedure in our study was 95.9%, and specificity was 99.9%. Conclusion. Our study proves that FEC is a reliable, informative diagnostic tool in detecting congenital heart defects with high specificity and sensitivity. With multidisciplinary approach, it provides an optimal time window for improving perinatal outcome.

scholarly journals An unrecognized combined congenital heart defect - Bicuspid aortic valve and ventricular septal defect as a cause of acute heart failure in adulthood

Cor et Vasa ◽  
2018 ◽  
Vol 60 (5) ◽  
pp. e512-e517 ◽  
Author(s):  
Kristýna Bayerová ◽  
Gabriela Dostálová ◽  
Zuzana Hlubocká ◽  
Tomáš Paleček ◽  
Jaroslav Hlubocký ◽  
...  
Keyword(s):  
Heart Failure ◽  
Aortic Valve ◽  
Ventricular Septal Defect ◽  
Acute Heart Failure ◽  
Bicuspid Aortic Valve ◽  
Congenital Heart Defect ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Defect

scholarly journals Hypertension and Heart Failure as Predictors of Mortality in an Adult Congenital Heart Defect Population

2021 ◽  
Vol 16 (4) ◽  
pp. 333-355
Author(s):  
Cheryl Raskind-Hood ◽  
Kashaine A. Gray ◽  
Jayne Morgan ◽  
Wendy M. Book
Keyword(s):  
Heart Failure ◽  
Congenital Heart Defect ◽  
Congenital Heart ◽  
Predictors Of Mortality ◽  
Heart Defect ◽  
Adult Congenital
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