scholarly journals 3D Compressed Convolutional Neural Network Differentiates Neuromyelitis Optical Spectrum Disorders From Multiple Sclerosis Using Automated White Matter Hyperintensities Segmentations

2020 ◽  
Vol 11 ◽  
Author(s):  
Zhuo Wang ◽  
Zhezhou Yu ◽  
Yao Wang ◽  
Huimao Zhang ◽  
Yishan Luo ◽  
...  

BackgroundMagnetic resonance imaging (MRI) has a wide range of applications in medical imaging. Recently, studies based on deep learning algorithms have demonstrated powerful processing capabilities for medical imaging data. Previous studies have mostly focused on common diseases that usually have large scales of datasets and centralized the lesions in the brain. In this paper, we used deep learning models to process MRI images to differentiate the rare neuromyelitis optical spectrum disorder (NMOSD) from multiple sclerosis (MS) automatically, which are characterized by scattered and overlapping lesions.MethodsWe proposed a novel model structure to capture 3D MRI images’ essential information and converted them into lower dimensions. To empirically prove the efficiency of our model, firstly, we used a conventional 3-dimensional (3D) model to classify the T2-weighted fluid-attenuated inversion recovery (T2-FLAIR) images and proved that the traditional 3D convolutional neural network (CNN) models lack the learning capacity to distinguish between NMOSD and MS. Then, we compressed the 3D T2-FLAIR images by a two-view compression block to apply two different depths (18 and 34 layers) of 2D models for disease diagnosis and also applied transfer learning by pre-training our model on ImageNet dataset.ResultsWe found that our models possess superior performance when our models were pre-trained on ImageNet dataset, in which the models’ average accuracies of 34 layers model and 18 layers model were 0.75 and 0.725, sensitivities were 0.707 and 0.708, and specificities were 0.759 and 0.719, respectively. Meanwhile, the traditional 3D CNN models lacked the learning capacity to distinguish between NMOSD and MS.ConclusionThe novel CNN model we proposed could automatically differentiate the rare NMOSD from MS, especially, our model showed better performance than traditional3D CNN models. It indicated that our 3D compressed CNN models are applicable in handling diseases with small-scale datasets and possess overlapping and scattered lesions.

2021 ◽  
Vol 9 (7) ◽  
pp. 755
Author(s):  
Kangkang Jin ◽  
Jian Xu ◽  
Zichen Wang ◽  
Can Lu ◽  
Long Fan ◽  
...  

Warm current has a strong impact on the melting of sea ice, so clarifying the current features plays a very important role in the Arctic sea ice coverage forecasting study field. Currently, Arctic acoustic tomography is the only feasible method for the large-range current measurement under the Arctic sea ice. Furthermore, affected by the high latitudes Coriolis force, small-scale variability greatly affects the accuracy of Arctic acoustic tomography. However, small-scale variability could not be measured by empirical parameters and resolved by Regularized Least Squares (RLS) in the inverse problem of Arctic acoustic tomography. In this paper, the convolutional neural network (CNN) is proposed to enhance the prediction accuracy in the Arctic, and especially, Gaussian noise is added to reflect the disturbance of the Arctic environment. First, we use the finite element method to build the background ocean model. Then, the deep learning CNN method constructs the non-linear mapping relationship between the acoustic data and the corresponding flow velocity. Finally, the simulation result shows that the deep learning convolutional neural network method being applied to Arctic acoustic tomography could achieve 45.87% accurate improvement than the common RLS method in the current inversion.


2019 ◽  
Author(s):  
Léon-Charles Tranchevent ◽  
Francisco Azuaje ◽  
Jagath C. Rajapakse

AbstractThe availability of high-throughput omics datasets from large patient cohorts has allowed the development of methods that aim at predicting patient clinical outcomes, such as survival and disease recurrence. Such methods are also important to better understand the biological mechanisms underlying disease etiology and development, as well as treatment responses. Recently, different predictive models, relying on distinct algorithms (including Support Vector Machines and Random Forests) have been investigated. In this context, deep learning strategies are of special interest due to their demonstrated superior performance over a wide range of problems and datasets. One of the main challenges of such strategies is the “small n large p” problem. Indeed, omics datasets typically consist of small numbers of samples and large numbers of features relative to typical deep learning datasets. Neural networks usually tackle this problem through feature selection or by including additional constraints during the learning process.We propose to tackle this problem with a novel strategy that relies on a graph-based method for feature extraction, coupled with a deep neural network for clinical outcome prediction. The omics data are first represented as graphs whose nodes represent patients, and edges represent correlations between the patients’ omics profiles. Topological features, such as centralities, are then extracted from these graphs for every node. Lastly, these features are used as input to train and test various classifiers.We apply this strategy to four neuroblastoma datasets and observe that models based on neural networks are more accurate than state of the art models (DNN: 85%-87%, SVM/RF: 75%-82%). We explore how different parameters and configurations are selected in order to overcome the effects of the small data problem as well as the curse of dimensionality. Our results indicate that the deep neural networks capture complex features in the data that help predicting patient clinical outcomes.


2020 ◽  
Author(s):  
Hao Gu ◽  
Guangwei Qing ◽  
Yu Wang ◽  
Sheng Hong ◽  
Guan Gui ◽  
...  

<div>Drones-aided ubiquitous applications play more and more important roles in our daily life. Accurate recognition of drones is required in aviation management due to their potential risks and even disasters.</div><div>Radio frequency (RF) fingerprinting-based recognition technology based on deep learning is considered as one of the effective approaches to extract hidden abstract features from RF data of drones. Existing deep learning-based methods are either a high computational burden or low accuracy.</div><div>In this paper, we propose a deep complex-valued convolutional neural network (DC-CNN) method based on RF fingerprinting for recognizing different drones.</div><div>Compared with existing recognition methods, the DC-CNN method has the advantages of high recognition accuracy, fast running time and small network complexity.</div><div>Nine algorithm models and two datasets are used to represent the superior performance of our system.</div><div>Experimental results show that our proposed DC-CNN can achieve recognition accuracy of 99.5\% and 74.1\% respectively on 4 and 8 classes of RF drone datasets.</div>


Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3608
Author(s):  
Chiao-Sheng Wang ◽  
I-Hsi Kao ◽  
Jau-Woei Perng

The early diagnosis of a motor is important. Many researchers have used deep learning to diagnose motor applications. This paper proposes a one-dimensional convolutional neural network for the diagnosis of permanent magnet synchronous motors. The one-dimensional convolutional neural network model is weakly supervised and consists of multiple convolutional feature-extraction modules. Through the analysis of the torque and current signals of the motors, the motors can be diagnosed under a wide range of speeds, variable loads, and eccentricity effects. The advantage of the proposed method is that the feature-extraction modules can extract multiscale features from complex conditions. The number of training parameters was reduced so as to solve the overfitting problem. Furthermore, the class feature map was proposed to automatically determine the frequency component that contributes to the classification using the weak learning method. The experimental results reveal that the proposed model can effectively diagnose three different motor states—healthy state, demagnetization fault state, and bearing fault state. In addition, the model can detect eccentric effects. By combining the current and torque features, the classification accuracy of the proposed model is up to 98.85%, which is higher than that of classical machine-learning methods such as the k-nearest neighbor and support vector machine.


2019 ◽  
Vol 12 (S8) ◽  
Author(s):  
Léon-Charles Tranchevent ◽  
Francisco Azuaje ◽  
Jagath C. Rajapakse

Abstract Background The availability of high-throughput omics datasets from large patient cohorts has allowed the development of methods that aim at predicting patient clinical outcomes, such as survival and disease recurrence. Such methods are also important to better understand the biological mechanisms underlying disease etiology and development, as well as treatment responses. Recently, different predictive models, relying on distinct algorithms (including Support Vector Machines and Random Forests) have been investigated. In this context, deep learning strategies are of special interest due to their demonstrated superior performance over a wide range of problems and datasets. One of the main challenges of such strategies is the “small n large p” problem. Indeed, omics datasets typically consist of small numbers of samples and large numbers of features relative to typical deep learning datasets. Neural networks usually tackle this problem through feature selection or by including additional constraints during the learning process. Methods We propose to tackle this problem with a novel strategy that relies on a graph-based method for feature extraction, coupled with a deep neural network for clinical outcome prediction. The omics data are first represented as graphs whose nodes represent patients, and edges represent correlations between the patients’ omics profiles. Topological features, such as centralities, are then extracted from these graphs for every node. Lastly, these features are used as input to train and test various classifiers. Results We apply this strategy to four neuroblastoma datasets and observe that models based on neural networks are more accurate than state of the art models (DNN: 85%-87%, SVM/RF: 75%-82%). We explore how different parameters and configurations are selected in order to overcome the effects of the small data problem as well as the curse of dimensionality. Conclusions Our results indicate that the deep neural networks capture complex features in the data that help predicting patient clinical outcomes.


2020 ◽  
Vol 6 (12) ◽  
pp. 132
Author(s):  
Mathé T. Zeegers ◽  
Daniël M. Pelt ◽  
Tristan van Leeuwen ◽  
Robert van Liere ◽  
Kees Joost Batenburg

An important challenge in hyperspectral imaging tasks is to cope with the large number of spectral bins. Common spectral data reduction methods do not take prior knowledge about the task into account. Consequently, sparsely occurring features that may be essential for the imaging task may not be preserved in the data reduction step. Convolutional neural network (CNN) approaches are capable of learning the specific features relevant to the particular imaging task, but applying them directly to the spectral input data is constrained by the computational efficiency. We propose a novel supervised deep learning approach for combining data reduction and image analysis in an end-to-end architecture. In our approach, the neural network component that performs the reduction is trained such that image features most relevant for the task are preserved in the reduction step. Results for two convolutional neural network architectures and two types of generated datasets show that the proposed Data Reduction CNN (DRCNN) approach can produce more accurate results than existing popular data reduction methods, and can be used in a wide range of problem settings. The integration of knowledge about the task allows for more image compression and higher accuracies compared to standard data reduction methods.


2021 ◽  
Vol 13 (13) ◽  
pp. 2450
Author(s):  
Aaron E. Maxwell ◽  
Timothy A. Warner ◽  
Luis Andrés Guillén

Convolutional neural network (CNN)-based deep learning (DL) is a powerful, recently developed image classification approach. With origins in the computer vision and image processing communities, the accuracy assessment methods developed for CNN-based DL use a wide range of metrics that may be unfamiliar to the remote sensing (RS) community. To explore the differences between traditional RS and DL RS methods, we surveyed a random selection of 100 papers from the RS DL literature. The results show that RS DL studies have largely abandoned traditional RS accuracy assessment terminology, though some of the accuracy measures typically used in DL papers, most notably precision and recall, have direct equivalents in traditional RS terminology. Some of the DL accuracy terms have multiple names, or are equivalent to another measure. In our sample, DL studies only rarely reported a complete confusion matrix, and when they did so, it was even more rare that the confusion matrix estimated population properties. On the other hand, some DL studies are increasingly paying attention to the role of class prevalence in designing accuracy assessment approaches. DL studies that evaluate the decision boundary threshold over a range of values tend to use the precision-recall (P-R) curve, the associated area under the curve (AUC) measures of average precision (AP) and mean average precision (mAP), rather than the traditional receiver operating characteristic (ROC) curve and its AUC. DL studies are also notable for testing the generalization of their models on entirely new datasets, including data from new areas, new acquisition times, or even new sensors.


2021 ◽  
Vol 11 (12) ◽  
pp. 3117-3122
Author(s):  
A. Sasidhar ◽  
M. S. Thanabal

Deep learning plays a key role in medical image processing. One of the applications of deep learning models in this domain is bone fracture detection from X-ray images. Convolutional neural network and its variants are used in wide range of medical image processing applications. MURA Dataset is commonly used in various studies that detect bone fractures and this work also uses that dataset, in specific the Humerus bone radiograph images. The humerus dataset in the MURA dataset contains both images with fracture and without fracture. The image with fracture includes images with metals which are removed in this work. Experimental analysis was made with two variants of convolutional neural network, DenseNet169 Model and the VGG Model. In case of the DenseNet169 model, a model with the pre trained weights of ImageNet and one without it is experimented. Results obtained with these variants of CNN are comparedand it shows that DenseNet169 model that uses pre-trained weights of ImageNet model performs better than the other two models.


2020 ◽  
Author(s):  
Hao Gu ◽  
Guangwei Qing ◽  
Yu Wang ◽  
Sheng Hong ◽  
Guan Gui ◽  
...  

<div>Drones-aided ubiquitous applications play more and more important roles in our daily life. Accurate recognition of drones is required in aviation management due to their potential risks and even disasters.</div><div>Radio frequency (RF) fingerprinting-based recognition technology based on deep learning is considered as one of the effective approaches to extract hidden abstract features from RF data of drones. Existing deep learning-based methods are either a high computational burden or low accuracy.</div><div>In this paper, we propose a deep complex-valued convolutional neural network (DC-CNN) method based on RF fingerprinting for recognizing different drones.</div><div>Compared with existing recognition methods, the DC-CNN method has the advantages of high recognition accuracy, fast running time and small network complexity.</div><div>Nine algorithm models and two datasets are used to represent the superior performance of our system.</div><div>Experimental results show that our proposed DC-CNN can achieve recognition accuracy of 99.5\% and 74.1\% respectively on 4 and 8 classes of RF drone datasets.</div>


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