scholarly journals Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

2020 ◽  
Vol 11 ◽  
Author(s):  
Jeffrey J. Lochhead ◽  
Junzhi Yang ◽  
Patrick T. Ronaldson ◽  
Thomas P. Davis
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Tight Junction ◽  
Structure Function ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Central Nervous System Disorders ◽  
Blood Brain

Glucocorticoid signalling and resistance at the blood–brain barrier in central nervous system disorders

2012 ◽  
Vol 56 (5-6) ◽  
pp. 355
Author(s):  
Christoph Kleinschnitz ◽  
Kinga Blecharz ◽  
Timo Kahles ◽  
Tobias Schwarz ◽  
Peter Kraft ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Central Nervous System Disorders ◽  
Blood Brain

scholarly journals Central nervous system delivery of molecules across the blood-brain barrier

2021 ◽  
pp. 104952
Author(s):  
Fabien Gosselet ◽  
Rodrigo Azevedo Loiola ◽  
Anna Roig ◽  
Anna Rosell ◽  
Maxime Culot
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Blood Brain

Understanding the Physiology of the Blood-Brain Barrier: In Vitro Models

Physiology ◽  
1998 ◽  
Vol 13 (6) ◽  
pp. 287-293 ◽  
Author(s):  
Gerald A. Grant ◽  
N. Joan Abbott ◽  
Damir Janigro
Keyword(s):  
Central Nervous System ◽  
Tissue Culture ◽  
Nervous System ◽  
Blood Brain Barrier ◽  
In Vitro Models ◽  
Brain Barrier ◽  
Blood Brain ◽  
Brain Tissue Culture ◽  
The Brain

Endothelial cells exposed to inductive central nervous system factors differentiate into a blood-brain barrier phenotype. The blood-brain barrier frequently obstructs the passage of chemotherapeutics into the brain. Tissue culture systems have been developed to reproduce key properties of the intact blood-brain barrier and to allow for testing of mechanisms of transendothelial drug permeation.

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