scholarly journals Gelatinases Cleave Dentin Sialoprotein Intracellularly

2020 ◽  
Vol 11 ◽  
Author(s):  
Xiaohui Gou ◽  
Yifan Xue ◽  
Huiwen Zheng ◽  
Guobin Yang ◽  
Shuo Chen ◽  
...  
Keyword(s):  
Dentin Sialoprotein

scholarly journals The Efficiency of Dentin Sialoprotein-Phosphophoryn Processing Is Affected by Mutations Both Flanking and Distant from the Cleavage Site

2013 ◽  
Vol 288 (8) ◽  
pp. 6024-6033 ◽  
Author(s):  
Robert T. Yang ◽  
Glendale L. Lim ◽  
Zhihong Dong ◽  
Arthur M. Lee ◽  
Colin T. Yee ◽  
...  
Keyword(s):  
Cleavage Site ◽  
Dentin Sialoprotein

Immunolocalization of osteopontin, osteocalcin, and dentin sialoprotein during dental root formation and early cementogenesis in the rat

2009 ◽  
Vol 9 (6) ◽  
pp. 833-841 ◽  
Author(s):  
Antonius L.J.J. Bronckers ◽  
Mary C. Farach-Carson ◽  
Erwin Van Waveren ◽  
William T. Butler
Keyword(s):  
Root Formation ◽  
Dentin Sialoprotein

scholarly journals N-terminal Dentin Sialoprotein fragment induces type I collagen production and upregulates dentinogenesis marker expression in osteoblasts

2016 ◽  
Vol 6 ◽  
pp. 190-196 ◽  
Author(s):  
Haytham Jaha ◽  
Dina Husein ◽  
Yoshio Ohyama ◽  
Dongliang Xu ◽  
Shigeki Suzuki ◽  
...  
Keyword(s):  
Type I Collagen ◽  
Type I ◽  
Collagen Production ◽  
Marker Expression ◽  
Dentin Sialoprotein

scholarly journals Laminin α2 Is Essential for Odontoblast Differentiation Regulating Dentin Sialoprotein Expression

2003 ◽  
Vol 279 (11) ◽  
pp. 10286-10292 ◽  
Author(s):  
Kenji Yuasa ◽  
Satoshi Fukumoto ◽  
Yoko Kamasaki ◽  
Aya Yamada ◽  
Emiko Fukumoto ◽  
...  
Keyword(s):  
Odontoblast Differentiation ◽  
Dentin Sialoprotein ◽  
Laminin Α2

scholarly journals Characterization of porcine dentin sialoprotein (DSP) and dentin sialophosphoprotein (DSPP) cDNA clones

2003 ◽  
Vol 111 (1) ◽  
pp. 60-67 ◽  
Author(s):  
Yasuo Yamakoshi ◽  
Jan C.-C. Hu ◽  
Shengxi Liu ◽  
Chuhua Zhang ◽  
Shinichiro Oida ◽  
...  
Keyword(s):  
Cdna Clones ◽  
Dentin Sialophosphoprotein ◽  
Dentin Sialoprotein

Expression of Dentin Sialoprotein (DSP) and Other Molecular Determinants by a New Cell Line from Dental Papillae, MDPC-23

1998 ◽  
Vol 37 (3-4) ◽  
pp. 251-261 ◽  
Author(s):  
Z. L. Sun ◽  
D. N. Fang ◽  
X. Y. Wu ◽  
H. H. Ritchie ◽  
C. Bègue-Kirn ◽  
...  
Keyword(s):  
Cell Line ◽  
New Cell Line ◽  
Molecular Determinants ◽  
Dentin Sialoprotein

The Expression of Dentin Sialophosphoprotein Gene in Bone

2002 ◽  
Vol 81 (6) ◽  
pp. 392-394 ◽  
Author(s):  
C. Qin ◽  
J.C. Brunn ◽  
E. Cadena ◽  
A. Ridall ◽  
H. Tsujigiwa ◽  
...  
Keyword(s):  
Specific Protein ◽  
Regulatory Mechanisms ◽  
Long Bone ◽  
Mrna Transcript ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Dentin Sialophosphoprotein ◽  
Dentin Phosphoprotein ◽  
Polymerase Chain ◽  
Dentin Sialoprotein

Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein (DSPP). DSP, DPP, and DSPP have been considered to be tooth-specific. To test for the expression of the dspp gene in bone, we performed Western immunoblots and reverse-transcription polymerase chain-reaction (RT-PCR). With Western immunoblots, we detected DSP in the Gdm/EDTA extracts of rat long bone, at a level of about 1/400 of that in dentin. Using RT-PCR, we detected DSPP mRNA in mouse calvaria. Similar to Western immunoblots, the results of RT-PCR indicated that the dspp gene is expressed at a lower level in bone than in dentin and odontoblasts. Analysis of the data shows that DSPP is not a tooth-specific protein, and that dramatically different regulatory mechanisms governing DSPP expression are involved in the bone and dentin.

N-acetyl Cysteine (NAC)-assisted Detoxification of PMMA Resin

2008 ◽  
Vol 87 (4) ◽  
pp. 372-377 ◽  
Author(s):  
M. Yamada ◽  
N. Kojima ◽  
A. Paranjpe ◽  
W. Att ◽  
H. Aita ◽  
...  
Keyword(s):  
Dental Pulp ◽  
Significant Degree ◽  
Cell Phenotype ◽  
Dependent Manner ◽  
Dental Pulp Cells ◽  
Concentration Dependent Manner ◽  
Pulp Cells ◽  
Acetyl Cysteine ◽  
Dentin Sialoprotein ◽  
Pmma Resin

Despite its proven cytotoxicity, poly-methyl methacrylate (PMMA) resin is one of the most frequently and extensively used materials in dental practice. This study hypothesized that an anti-oxidant amino acid, N-acetyl cysteine (NAC), has the potential to detoxify this material. Ten percent of the rat dental pulp cells were viable when cultured on the PMMA resin for 24 hours, while over 70% of the cells were viable on the NAC-added resin. Nearly all suppressed alkaline phosphatase activity, matrix mineralizing capability, and odontoblastic gene expression, such as dentin sialoprotein, on the untreated control resin was recovered by NAC in a concentration-dependent manner. A Ca/P ratio of 1.65 was found in the extracellular matrix of cultures on NAC-added resin, while that in the untreated resin culture was 0.70. The addition of NAC to PMMA resin significantly ameliorated its cytotoxicity to the dental pulp cells and restored their odontoblast-like cell phenotype to a biologically significant degree.

scholarly journals Identification and Characterization of the Carboxyl-terminal Region of Rat Dentin Sialoprotein

2000 ◽  
Vol 276 (2) ◽  
pp. 904-909 ◽  
Author(s):  
Chunlin Qin ◽  
Richard G. Cook ◽  
Ralph S. Orkiszewski ◽  
William T. Butler
Keyword(s):  
Terminal Region ◽  
Carboxyl Terminal ◽  
Dentin Sialoprotein ◽  
Identification And Characterization
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