scholarly journals Tissue Oxygenation in Response to Different Relative Levels of Blood-Flow Restricted Exercise

2019 ◽  
Vol 10 ◽  
Author(s):  
Joana F. Reis ◽  
Pedro Fatela ◽  
Goncalo V. Mendonca ◽  
Joao R. Vaz ◽  
Maria J. Valamatos ◽  
...  
Keyword(s):  
Blood Flow ◽  
Tissue Oxygenation ◽  
Blood Flow Restricted Exercise

A614 BLOOD FLOW TO SPLANCHNIC ORGANS AND TISSUE OXYGENATION OF LIVER AND PANCREAS DURING ENFLURANE INDUCED HYPOTENSION

1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA
Author(s):  
B. Vollmar ◽  
T. Kerner ◽  
M. Vierl ◽  
P. F. Conzen ◽  
H. Habazettl ◽  
...  
Keyword(s):  
Blood Flow ◽  
Tissue Oxygenation ◽  
Induced Hypotension ◽  
Liver And Pancreas

scholarly journals Blood flow restricted exercise for athletes: A review of available evidence

2016 ◽  
Vol 19 (5) ◽  
pp. 360-367 ◽  
Author(s):  
Brendan R. Scott ◽  
Jeremy P. Loenneke ◽  
Katie M. Slattery ◽  
Ben J. Dascombe
Keyword(s):  
Blood Flow ◽  
Blood Flow Restricted Exercise

scholarly journals Increased tissue oxygenation explains the attenuation of hyperemia upon repetitive pneumatic compression of the lower leg

2017 ◽  
Vol 123 (6) ◽  
pp. 1451-1460 ◽  
Author(s):  
Alessandro Messere ◽  
Gianluca Ceravolo ◽  
Walter Franco ◽  
Daniela Maffiodo ◽  
Carlo Ferraresi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Blood Volume ◽  
Near Infrared ◽  
Tissue Oxygenation ◽  
Femoral Vein ◽  
Lower Leg ◽  
Local Circulation ◽  
Doppler Measurement ◽  
Key Factor ◽  
Interstimulus Intervals

The rapid hyperemia evoked by muscle compression is short lived and was recently shown to undergo a rapid decrease even in spite of continuing mechanical stimulation. The present study aims at investigating the mechanisms underlying this attenuation, which include local metabolic mechanisms, desensitization of mechanosensitive pathways, and reduced efficacy of the muscle pump. In 10 healthy subjects, short sequences of mechanical compressions ( n = 3–6; 150 mmHg) of the lower leg were delivered at different interstimulus intervals (ranging from 20 to 160 s) through a customized pneumatic device. Hemodynamic monitoring included near-infrared spectroscopy, detecting tissue oxygenation and blood volume in calf muscles, and simultaneous echo-Doppler measurement of arterial (superficial femoral artery) and venous (femoral vein) blood flow. The results indicate that 1) a long-lasting (>100 s) increase in local tissue oxygenation follows compression-induced hyperemia, 2) compression-induced hyperemia exhibits different patterns of attenuation depending on the interstimulus interval, 3) the amplitude of the hyperemia is not correlated with the amount of blood volume displaced by the compression, and 4) the extent of attenuation negatively correlates with tissue oxygenation ( r = −0,78, P < 0.05). Increased tissue oxygenation appears to be the key factor for the attenuation of hyperemia upon repetitive compressive stimulation. Tissue oxygenation monitoring is suggested as a useful integration in medical treatments aimed at improving local circulation by repetitive tissue compression. NEW & NOTEWORTHY This study shows that 1) the hyperemia induced by muscle compression produces a long-lasting increase in tissue oxygenation, 2) the hyperemia produced by subsequent muscle compressions exhibits different patterns of attenuation at different interstimulus intervals, and 3) the extent of attenuation of the compression-induced hyperemia is proportional to the level of oxygenation achieved in the tissue. The results support the concept that tissue oxygenation is a key variable in blood flow regulation.

Abstract 9839: Beta Blockers Improve Renal Tissue Oxygenation in Hypertensive Patients Suspected of Renal Artery Stenosis

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Michael E Hall ◽  
Michael V Rocco ◽  
Timothy M Morgan ◽  
Craig A Hamilton ◽  
Jennifer H Jordan ◽  
...  
Keyword(s):  
Blood Flow ◽  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Beta Blocker ◽  
Tissue Oxygenation ◽  
Beta Blockers ◽  
Renal Tissue ◽  
Artery Stenosis ◽  
Blocker Therapy ◽  
Hypertensive Patients

Background: Chronic renal hypoxia influences the progression of chronic kidney disease (CKD). Blood oxygen level dependent (BOLD) magnetic resonance (MR) is a noninvasive tool for assessment of renal tissue oxygenation. Beta blockers reduce cardiovascular mortality in patients with CKD and systolic heart failure, however the mechanisms of this benefit remain unclear. We sought to determine the association between beta blocker use, renal cortical and medullary oxygenation, and renal blood flow in hypertensive patients suspected of renal artery stenosis. Hypothesis: Chronic receipt of beta blockers will be associated with improved renal tissue oxygenation as assessed by BOLD MR. Methods: We measured renal cortical and medullary oxygenation using BOLD MR and renal artery blood flow using MR phase contrast techniques in 38 participants suspected of renal artery stenosis. Results: Chronic beta blocker therapy was associated with improved renal cortical (p=0.0007) and medullary (p=0.03) oxygenation (Figure). Receipt of angiotensin converting enzyme inhibitors or angiotensin receptor blockers was associated with reduced medullary oxygenation (p=0.01). In a multivariable model including gender, hemoglobin, diabetes, loop diuretic use, and mineralocorticoid use, chronic receipt of beta blockers was the only significant predictor of renal tissue oxygenation (β= 8.4, p=0.008). Conclusions: Beta blocker therapy was associated with improved renal oxygenation independent of renal blood flow suggesting may these findings may be related to reduced renal oxygen consumption. In addition to their known benefits to reduce cardiovascular mortality in patients with renal disease, beta blockers may reduce or prevent progression of renal dysfunction in patients with hypertension, diabetes, and renovascular disease. These observations may have important implications for treatment of patients with CKD.

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