scholarly journals Changes to the Human Serum Proteome in Response to High Intensity Interval Exercise: A Sequential Top-Down Proteomic Analysis

2019 ◽  
Vol 10 ◽  
Author(s):  
Nigel Kurgan ◽  
Nour Noaman ◽  
Melissa R. Pergande ◽  
Stephanie M. Cologna ◽  
Jens R. Coorssen ◽  
...  
Keyword(s):  
Human Serum ◽  
High Intensity ◽  
Proteomic Analysis ◽  
Top Down ◽  
Interval Exercise ◽  
Serum Proteome ◽  
High Intensity Interval

Effects of L-citrulline supplementation on nitric oxide and antioxidant markers after high-intensity interval exercise in young men: a randomized controlled trial

2021 ◽  
pp. 1-23
Author(s):  
Kosar Valaei ◽  
Javad Mehrabani ◽  
Alexei Wong
Keyword(s):  
Nitric Oxide ◽  
High Intensity ◽  
Controlled Trial ◽  
Young Men ◽  
No Production ◽  
Double Blind ◽  
Interval Exercise ◽  
Damage Indices ◽  
High Intensity Interval ◽  
Antioxidant Markers

Abstract L-citrulline (L-Cit) is a nonessential amino acid that stimulates nitric oxide (NO) production and improves exercise performance by reducing muscle damage indices; however, the direct benefits of L-Cit on antioxidant markers are unclear. The aim of this study was to examine antioxidant responses to high-intensity interval exercise following acute L-Cit supplementation. Nine young men (21 ± 1 years) participated in a double-blind crossover study in which they received 12 g of L-Cit and placebo (PL) an hour prior to high-intensity interval exercise on two occasions, separated by a seven-day washout period. Blood samples were obtained before (PRE), immediately after (IP), 10 (10P), and 30 min after exercise (30P) from the cubital vein using standard procedures. Serum concentrations of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), and NO metabolites (NOx) were measured. The exercise protocol significantly elevated SOD (p = 0.01) and GPx (p = 0.048) from PRE to 10P in the L-Cit group with greater changes than the PL group. CAT concentrations increased IP (p = 0.014) and remained elevated at 10P (p = 0.03) and 30P (p = 0.015) in both the L-Cit and PL conditions. NOx concentrations increased IP (p = 0.05) in the L-Cit group with greater changes than PL group in PRE to IP, PRE to 10P, and PRE to 30P (p < 0.05). Our data indicate that L-Cit supplementation (single 12 g dose pre-exercise) induces improvements in antioxidant markers following a session of high-intensity interval exercise in young men.

A Single Session of Low-Volume High-Intensity Interval Exercise Reduces Ambulatory Blood Pressure in Normotensive Men

2017 ◽  
Vol 31 (8) ◽  
pp. 2263-2269 ◽  
Author(s):  
Teresa C.B. Dantas ◽  
Luiz F. Farias Junior ◽  
Danniel T. Frazão ◽  
Paulo H.M. Silva ◽  
Altieres E. Sousa Junior ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ambulatory Blood Pressure ◽  
High Intensity ◽  
Single Session ◽  
Interval Exercise ◽  
Low Volume ◽  
High Intensity Interval

Acute affective responses to high-intensity interval exercise: Implications on the use of different stimulus-recovery amplitudes

2021 ◽  
pp. 1-11
Author(s):  
Bruno Ribeiro Ramalho Oliveira ◽  
Tony Meireles Santos ◽  
Renato de Carvalho Guerreiro ◽  
Igor D’Amorim ◽  
Eduardo Lattari ◽  
...  
Keyword(s):  
High Intensity ◽  
Affective Responses ◽  
Interval Exercise ◽  
High Intensity Interval

scholarly journals Acute high-intensity interval exercise induces greater levels of serum brain-derived neurotrophic factor in obese individuals

2018 ◽  
Vol 243 (14) ◽  
pp. 1153-1160 ◽  
Author(s):  
Alexandra L Rodriguez ◽  
Michael Whitehurst ◽  
Brandon G Fico ◽  
Katelyn M Dodge ◽  
Peter J Ferrandi ◽  
...  
Keyword(s):  
Blood Lactate ◽  
High Intensity ◽  
Normal Weight ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Bdnf Expression ◽  
Interval Exercise ◽  
Obese Population ◽  
Obese Subjects ◽  
High Intensity Interval

Obesity may attenuate the expression of brain-derived neurotrophic factor (BDNF), thereby increasing the risk of cognitive dysfunction. High-intensity interval exercise (HIIE) has been shown to be as or more effective than continuous moderate-intensity exercise (CME) in promoting the expression of BDNF in normal-weight individuals. Therefore, the primary purpose of this study was to examine whether or not acute HIIE could be utilized as a practical model to explore the BDNF response in obese versus normal-weight subjects when compared to acute CME. The potential relationship of exercise-induced BDNF with blood lactate and cortisol was also examined. Twelve male subjects (six obese and six normal-weight) participated in a counterbalanced and caloric equated experiment: HIIE (30 min, 4 intervals of 4 min at 80%–90% of VO2max with 3 min of active recovery at 50–60% VO2max) and CME (38 min at 50%–60% VO2max). Blood samples were collected prior to, immediately following exercise, and 1 h into recovery for measurements of serum BDNF, blood lactate, and plasma cortisol. Our results showed that the BDNF response to acute HIIE was greater than CME in obese subjects when compared to normal-weight subjects. Similarly, although acute HIIE induced greater blood lactate and plasma cortisol levels than CME, obese subjects produced less blood lactate, but no difference in cortisol than normal-weight subjects. These findings suggest that acute HIIE may be a more effective protocol to upregulate BDNF expression in an obese population, independent of increased lactate and cortisol levels. Impact statement High-intensity interval exercise (HIIE) has been shown to be a time-efficient exercise strategy that provides similar or superior physiological benefits as traditional continuous moderate-intensity exercise (CME). Our previous study demonstrated an equivalent elevation on the BDNF response in both obese and normal-weight individuals following 30 min of acute CME. To discover a time-efficient exercise strategy to improve brain health in an obese population, the present study found that obese individuals elicit a greater level of BDNF following acute HIIE versus CME than normal-weight individuals. These findings indicate that acute HIIE may be an effective strategy to upregulate BDNF expression in obese individuals.

Effect Of Obesity On Leukocyte Activation In Response To 1 Bout of High-Intensity Interval Exercise In Children

2015 ◽  
Vol 47 ◽  
pp. 892
Author(s):  
Abraham S. Chiu ◽  
Peter Horvath ◽  
Goutham Ganesan ◽  
Robert V. Warren ◽  
Frank Zaldivar ◽  
...  
Keyword(s):  
High Intensity ◽  
Leukocyte Activation ◽  
Interval Exercise ◽  
High Intensity Interval

scholarly journals Post-exercise hypotension in response to high-intensity interval exercise: Potential mechanisms

2021 ◽  
Vol 40 (10) ◽  
pp. 797-799
Author(s):  
Raphael José Perrier-Melo ◽  
Antônio Henrique Germano-Soares ◽  
Aline Freitas Brito ◽  
Iago Vilela Dantas ◽  
Manoel da Cunha Costa
Keyword(s):  
High Intensity ◽  
Post Exercise ◽  
Interval Exercise ◽  
High Intensity Interval ◽  
Post Exercise Hypotension

scholarly journals Effects of Pyruvate Supplementation on High-intensity Interval Exercise Induced Metabolic Acidosis and Repeated Sprint Exercise Performance of College Soccer Athletes

2021 ◽  
Author(s):  
yanping yang ◽  
Junqiang Qiu ◽  
Mengyue Wang ◽  
Lin Feng ◽  
Dan Luo ◽  
...  
Keyword(s):  
Metabolic Acidosis ◽  
High Intensity ◽  
Energy Contribution ◽  
Sprint Exercise ◽  
Interval Exercise ◽  
Repeated Sprint ◽  
Blood Ph ◽  
High Intensity Interval ◽  
The Impact ◽  
Oxidative System

Abstract Background: The effects of pyruvate on metabolic acidosis and oxidative metabolism had been studied. The ability to attenuate acidosis and improve oxidative system contribution are critical to the performance of team sport athletes during perform multiple high-intensity exercise over a limited period of time. This study aimed to investigate the impact of pyruvate supplementation on energy metabolism and metabolic acidosis during high-intensity interval exercise (HIIE), as well as to evaluate its role on repeated sprint exercise (RSE) performance.Methods: 14 well-trained male college soccer athletes (age: 20 ± 2 years, body fat: 13.11 ± 3.50 %) were studied in a randomized, double-blind, cross-over study. The participants ingested either 0.1g/kg/d of pyruvate or a placebo for 1-week. Metabolic acidosis was induced by HIIE after the supplement period, and RSE ability in the acidosis state was assessed. Venous blood pH, bicarbonate (HCO3-) and base excess (BE) were measured at baseline, pre-HIIE, post-HIIE, pre-RSE and post-RSE. Finger-stick blood lactate were collected at baseline, immediately after each bout of HIIE and 3, 5, 7, 10 min after HIIE. The energy systems contribution during HIIE were estimated. Results: Blood pH, HCO3- and BE were significantly lower than baseline after HIIE (p < 0.01) in both pyruvate group (PYR) and placebo group (PLA). Compared to PLA, the blood pH, HCO3- and BE were significantly improved in PYR at pre-HIIE (p < 0.01), post-HIIE (p < 0.01) and pre-RSE (p < 0.01). Furthermore, blood BE remained higher in PYR than PLA till end of RSE (p < 0.05). The contribution of oxidative system in the fourth bout of HIIE was higher in PYR than PLA (p < 0.05). In PLA, the ratio of total anaerobic energy contribution during HIIE was higher than that of aerobic (oxidative) (p < 0.01), but not in PYR (p > 0.05). Relative peak power (RPP) of first, fifth sprint, relative average power (RAP) of fifth sprint, the average of RPP and RAP during RSE were significantly improved in PYR compared with PLA (p < 0.05). While no significant changes in the PD% of each bout (p > 0.05) or average PD% (p > 0.05) were observed between the two groups. Conclusion: Pyruvate supplementation for 1-week enhances oxidative system energy contribution and buffers metabolic acidosis during HIIE, and improves RSE performance in acidosis.

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