scholarly journals Chronic Low-Level Vagus Nerve Stimulation Improves Long-Term Survival in Salt-Sensitive Hypertensive Rats

2019 ◽  
Vol 10 ◽  
Author(s):  
Elizabeth M. Annoni ◽  
Dusty Van Helden ◽  
Yugene Guo ◽  
Brett Levac ◽  
Imad Libbus ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Hypertensive Rats ◽  
Term Survival ◽  
Long Term Survival ◽  
Low Level

Long Term Effects of Low Frequency (10 Hz) Vagus Nerve Stimulation on EEG and Heart Rate Variability in Crohn's Disease: A Case Report

2014 ◽  
Vol 7 (6) ◽  
pp. 914-916 ◽  
Author(s):  
Didier Clarençon ◽  
Sonia Pellissier ◽  
Valérie Sinniger ◽  
Astrid Kibleur ◽  
Dominique Hoffman ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Crohn’S Disease ◽  
Case Report ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Low Frequency ◽  
Long Term Effects

Vagus nerve stimulation for drug-resistant epilepsy

2019 ◽  
Vol 20 (3) ◽  
pp. 189-198 ◽  
Author(s):  
Laura Pérez-Carbonell ◽  
Howard Faulkner ◽  
Sean Higgins ◽  
Michalis Koutroumanidis ◽  
Guy Leschziner
Keyword(s):  
Vagus Nerve ◽  
Seizure Frequency ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Therapeutic Option ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy ◽  
Randomised Controlled

Vagus nerve stimulation (VNS) is a neuromodulatory therapeutic option for drug-resistant epilepsy. In randomised controlled trials, VNS implantation has resulted in over 50% reduction in seizure frequency in 26%–40% of patients within 1 year. Long-term uncontrolled studies suggest better responses to VNS over time; however, the assessment of other potential predictive factors has led to contradictory results. Although initially designed for managing focal seizures, its use has been extended to other forms of drug-resistant epilepsy. In this review, we discuss the evidence supporting the use of VNS, its impact on seizure frequency and quality of life, and common adverse effects of this therapy. We also include practical guidance for the approach to and the management of patients with VNS in situ.

Long-term survival in a patient with low-level inflammatory markers and liver metastasis, converted resectable by TACE

Immunotherapy ◽  
2017 ◽  
Vol 9 (13) ◽  
pp. 1067-1069
Author(s):  
Malkhaz Mizandari ◽  
Natela Paksashvili ◽  
Nino Kikodze ◽  
Tamta Azrumelashvili ◽  
Ia Pantsulaia ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Inflammatory Markers ◽  
Term Survival ◽  
Long Term Survival ◽  
Low Level

Long term effect of vagus nerve stimulation in pediatric intractable epilepsy: an extended follow-up

2016 ◽  
Vol 32 (4) ◽  
pp. 641-646 ◽  
Author(s):  
Ayse Serdaroglu ◽  
Ebru Arhan ◽  
Gökhan Kurt ◽  
Atilla Erdem ◽  
Tugba Hirfanoglu ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Intractable Epilepsy ◽  
Term Effect ◽  
Long Term Effect

Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Stroke: One-Year Follow-up

2020 ◽  
Vol 34 (7) ◽  
pp. 609-615
Author(s):  
Jesse Dawson ◽  
Navzer D. Engineer ◽  
Cecília N. Prudente ◽  
David Pierce ◽  
Gerard Francisco ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Vagus Nerve ◽  
Upper Limb ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Exercise Program ◽  
Home Exercise ◽  
Home Exercise Program

Background. Vagus nerve stimulation (VNS) paired with rehabilitation may improve upper-limb impairment and function after ischemic stroke. Objective. To report 1-year safety, feasibility, adherence, and outcome data from a home exercise program paired with VNS using long-term follow-up data from a randomized double-blind study of rehabilitation therapy paired with Active VNS (n = 8) or Control VNS (n = 9). Methods. All people were implanted with a VNS device and underwent 6 weeks in clinic therapy with Control or Active VNS followed by home exercises through day 90. Thereafter, participants and investigators were unblinded. The Control VNS group then received 6 weeks in-clinic Active VNS (Cross-VNS group). All participants then performed an individualized home exercise program with self-administered Active VNS. Data from this phase are reported here. Outcome measures were Fugl-Meyer Assessment—Upper Extremity (FMA-UE), Wolf Motor Function Test (Functional and Time), Box and Block Test, Nine-Hole Peg Test, Stroke Impact Scale, and Motor Activity Log. Results. There were no VNS treatment–related serious adverse events during the long-term therapy. Two participants discontinued prior to receiving the full crossover VNS. On average, participants performed 200 ± 63 home therapy sessions, representing device use on 57.4% of home exercise days available for each participant. Pooled analysis revealed that 1 year after randomization, the FMA-UE score increased by 9.2 points (95% CI = 4.7 to 13.7; P = .001; n = 15). Other functional measures were also improved at 1 year. Conclusions. VNS combined with rehabilitation is feasible, with good long-term adherence, and may improve arm function after ischemic stroke.

scholarly journals Long-Term Performance of Vagus Nerve Stimulation Lead: Low Rate of Complications and Failures

2019 ◽  
Vol 25 (8) ◽  
pp. S177-S178
Author(s):  
Imad Libbus ◽  
Scott R. Stubbs ◽  
Scott Mindrebo ◽  
Bruce H. KenKnight ◽  
Lorenzo A. DiCarlo
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Long Term Performance ◽  
Term Performance ◽  
Low Rate

scholarly journals Long-term results with vagus nerve stimulation in children with pharmacoresistant epilepsy

Seizure ◽  
2006 ◽  
Vol 15 (7) ◽  
pp. 491-503 ◽  
Author(s):  
Andreas V. Alexopoulos ◽  
Prakash Kotagal ◽  
Tobias Loddenkemper ◽  
Jeffrey Hammel ◽  
William E. Bingaman
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Long Term Results ◽  
Pharmacoresistant Epilepsy

Long-term vagus nerve stimulation in the treatment of Lennox–Gastaut syndrome

2009 ◽  
Vol 16 (2) ◽  
pp. 321-324 ◽  
Author(s):  
Konstantin Kostov ◽  
Hrisimir Kostov ◽  
Erik Taubøll
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation
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